Faculty

Institution

Unit

Venue

Davin Jensen

Medical College of Wisconsin

Affiliations

Biochemistry Department

NoneDavin Jensen is currently serving as a Biochemistry faculty at Medical College of Wisconsin.

Honors

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Experiences

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Education

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Davin Jensen

Medical College of Wisconsin

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biochemistry molecular biology structural biology protein science protein structure nuclear magnetic resonance structural molecular biology pharmacology biomolecular engineering biomolecular structure drug discovery receptors chemical biology molecular structure nuclear magnetic resonance spectroscopy c-terminal transmembrane domain protein-detected nmr spectroscopy tumor biology enzyme inhibition receptor (biochemistry) tumor suppressors structural genomics protein nmr protein purification protein expression enzymes structural chemistry pharmacological research leukemia thyroid oncogenes cancer cells cancer letter thrombosis vascular biology molecular diagnostics g protein-coupled receptor mechanisms of action plant biochemistry surfactant solutions protein mass spectrometry protein refolding signaling pathways receptor tyrosine kinases antibiotic resistance chemical analysis endocrine-related cancers tumoral pathology malignant disease cancer treatment structural bioinformatics computational genomics mitochondrial function principal component analysis chemical measurement gene evolution allelic variant mutagenesis structure determination x-ray crystallography protein phosphatases start proteins abscisic acid receptors gate-latch-lock mechanism hormone signalling selective activation aba receptors structural basis tryptophan lock simple scaffold aba receptor agonist robust mass spectrometry solution structure recombinant chemokines

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in Ehmt1. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Young-In ChiSalomão D. JorgeDavin R. JensenBrian C. SmithBrian F. VolkmanAngela J. MathisonGwen LomberkMichael T. ZimmermannRaul Urrutia

kleefstra syndrome variantsdomain-specific interpretationgenomicsstructural genomicsmolecular biologycomputational genomics

Beyond Structural Bioinformatics for Genomics With Dynamics Characterization of an Expanded Kras Mutational Landscape. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Brian D. RatnasingheNeshatul HaqueJessica B. WagenknechtDavin R. JensenGuadalupe V. EsparzaElise N. LeverenceThiago Milech De AssuncaoAngela J. MathisonGwen LomberkBrian C. SmithBrian F. VolkmanRaul UrrutiaMichael T. Zimmermann

dynamics characterizationkras mutational landscapegenomicsstructural bioinformaticsmolecular biology

De Novo Design of Small Beta Barrel Proteins. Proceedings of the National Academy of Sciences (2023)

David E. KimDavin R. JensenDavid FeldmanDoug TischerAyesha SaleemCameron M. ChowXinting LiLauren CarterLukas MillesHannah NguyenAlex KangAsim K. BeraFrancis C. PetersonBrian F. VolkmanSergey OvchinnikovDavid Baker

protein scienceprotein designprotein engineeringbiomolecular engineeringstructural biology

Fragment-Based Drug Discovery of Small Molecule Ligands for the Human Chemokine Ccl28. SLAS DISCOVERY (2023)

Angela L. ZhouDavin R. JensenFrancis C. PetersonMonica A. ThomasRoman R. SchlimgenMichael B. DwinellBrian C. SmithBrian F. Volkman

drug discoveryfragment-based drug discoverysmall molecule ligandspharmacology

Fragment-Based Screening by Protein-Detected Nmr Spectroscopy. Methods in enzymology on CD-ROM/Methods in enzymology (2023)

Paul J. KerberRaymundo NuñezDavin R. JensenAngela L. ZhouFrancis C. PetersonR. Blake HillBrian F. VolkmanBrian C. Smith

protein-detected nmr spectroscopybiochemistrynuclear magnetic resonance spectroscopynuclear magnetic resonancefragment-based screening

Overlapping and Distinct Functions of an Extended Repertoire of Kras Mutations. Research Square (Research Square) (2023)

Michael ZimmermannAngela MathisonXuan LiElise LeverenceDavin JensenGuadalupe EsparzaThiago Milech De AssuncaoBrian SmithBrian VolkmanGwen LomberkRaul Urrutia

genetic recombinationmutagenesisextended repertoireallelic variantkras mutationstranscription (biology)molecular biologyevolutionary biologygeneticsdistinct functionsmolecular evolutiongene expressiongene evolutiongenetic variation

Selective and Cell-Active Pbrm1 Bromodomain Inhibitors Discovered Through Nmr Fragment Screening. Journal of Medicinal Chemistry (2022)

Shifali ShishodiaRaymundo NuñezBrayden P. StrohmierKarina L. BurschChristopher J. GoetzMichael D. OlpDavin R. JensenTyler G. FenskeSandra C. Ordonez-RubianoMaya E. BlauMallory K. RoachFrancis C. PetersonBrian F. VolkmanEmily C. DykhuizenBrian C. Smith

nmr fragment screeningmedicinal chemistrymedicinepharmacologydrug discoverynuclear magnetic resonance

The Dimeric Form of Cxcl12 Binds to Atypical Chemokine Receptor 1. Science Signaling (2021)

Julia C. GutjahrKyler S. CrawfordDavin R. JensenPrachi NaikFrancis C. PetersonGuerric P. B. SamsonDaniel F. LeglerJohan DucheneChristopher T. VeldkampAntal RotBrian F. Volkman

receptor tyrosine kinasesprotein sciencecell signalingimmunologysignaling pathwaysbiochemistryreceptor (biochemistry)molecular biologysignal transductiongene expressionreceptorsdimeric form

Development of a Molecular Probe Targeting Mitochondrial Fission Protein Fis1. The FASEB Journal (2018)

John M. EgnerDavin R. JensenMichael D. OlpBrian F. VolkmanFrancis C. PetersonBrian C. SmithMichael E. WidlanskyR. Blake Hill

biophysicsbiochemistrymitochondrial functionmolecular biologymolecular probestructural biology

Front Cover: Development and Validation of 2D Difference Intensity Analysis for Chemical Library Screening by Protein‐Detected Nmr Spectroscopy (Chembiochem 5/2018). ChemBioChem (2018)

John M. EgnerDavin R. JensenMichael D. OlpNolan W. KennedyBrian F. VolkmanFrancis C. PetersonBrian C. SmithR. Blake Hill

principal component analysisprotein-detected nmr spectroscopychemical library screeningprotein sciencechemical measurementanalytical chemistrybiochemistrynuclear magnetic resonance spectroscopychemical biologymolecular diagnosticschemistryprotein nmrdifference intensity analysisnuclear magnetic resonancebiomolecular engineering

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Davin Jensen

Medical College of Wisconsin

Affiliations

Biochemistry Department

NoneDavin Jensen is currently serving as a Biochemistry faculty at Medical College of Wisconsin.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Davin Jensen

Medical College of Wisconsin

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in Ehmt1. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Young-In ChiSalomão D. JorgeDavin R. JensenBrian C. SmithBrian F. VolkmanAngela J. MathisonGwen LomberkMichael T. ZimmermannRaul Urrutia

kleefstra syndrome variantsdomain-specific interpretationgenomicsstructural genomicsmolecular biologycomputational genomics

Beyond Structural Bioinformatics for Genomics With Dynamics Characterization of an Expanded Kras Mutational Landscape. bioRxiv (Cold Spring Harbor Laboratory) (2023)

dynamics characterizationkras mutational landscapegenomicsstructural bioinformaticsmolecular biology

De Novo Design of Small Beta Barrel Proteins. Proceedings of the National Academy of Sciences (2023)

protein scienceprotein designprotein engineeringbiomolecular engineeringstructural biology

Fragment-Based Drug Discovery of Small Molecule Ligands for the Human Chemokine Ccl28. SLAS DISCOVERY (2023)

Angela L. ZhouDavin R. JensenFrancis C. PetersonMonica A. ThomasRoman R. SchlimgenMichael B. DwinellBrian C. SmithBrian F. Volkman

drug discoveryfragment-based drug discoverysmall molecule ligandspharmacology

Fragment-Based Screening by Protein-Detected Nmr Spectroscopy. Methods in enzymology on CD-ROM/Methods in enzymology (2023)

Paul J. KerberRaymundo NuñezDavin R. JensenAngela L. ZhouFrancis C. PetersonR. Blake HillBrian F. VolkmanBrian C. Smith

protein-detected nmr spectroscopybiochemistrynuclear magnetic resonance spectroscopynuclear magnetic resonancefragment-based screening

Overlapping and Distinct Functions of an Extended Repertoire of Kras Mutations. Research Square (Research Square) (2023)

Michael ZimmermannAngela MathisonXuan LiElise LeverenceDavin JensenGuadalupe EsparzaThiago Milech De AssuncaoBrian SmithBrian VolkmanGwen LomberkRaul Urrutia

Selective and Cell-Active Pbrm1 Bromodomain Inhibitors Discovered Through Nmr Fragment Screening. Journal of Medicinal Chemistry (2022)

nmr fragment screeningmedicinal chemistrymedicinepharmacologydrug discoverynuclear magnetic resonance

The Dimeric Form of Cxcl12 Binds to Atypical Chemokine Receptor 1. Science Signaling (2021)

Julia C. GutjahrKyler S. CrawfordDavin R. JensenPrachi NaikFrancis C. PetersonGuerric P. B. SamsonDaniel F. LeglerJohan DucheneChristopher T. VeldkampAntal RotBrian F. Volkman

receptor tyrosine kinasesprotein sciencecell signalingimmunologysignaling pathwaysbiochemistryreceptor (biochemistry)molecular biologysignal transductiongene expressionreceptorsdimeric form

Development of a Molecular Probe Targeting Mitochondrial Fission Protein Fis1. The FASEB Journal (2018)

John M. EgnerDavin R. JensenMichael D. OlpBrian F. VolkmanFrancis C. PetersonBrian C. SmithMichael E. WidlanskyR. Blake Hill

biophysicsbiochemistrymitochondrial functionmolecular biologymolecular probestructural biology

Front Cover: Development and Validation of 2D Difference Intensity Analysis for Chemical Library Screening by Protein‐Detected Nmr Spectroscopy (Chembiochem 5/2018). ChemBioChem (2018)

John M. EgnerDavin R. JensenMichael D. OlpNolan W. KennedyBrian F. VolkmanFrancis C. PetersonBrian C. SmithR. Blake Hill

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