Faculty

Institution

Unit

Venue

Julien Roche

Associate Professor

Iowa State University

Affiliations

College of Liberal Arts and Sciences

Biochemistry, Biophysics, and Molecular Biology

College of Agriculture and Life Sciences

Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology

Julien Roche is currently serving as a Biochemistry, Biophysics, And Molecular Biology Associate Professor at Iowa State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Julien Roche

Iowa State University

Associate Professor

You can click a keyword to filter the displayed items

protein science biophysics molecular biology protein structure structural biology protein folding biochemistry structural molecular biology protein nmr nuclear magnetic resonance biomolecular structure biophysical chemistry hiv molecular biophysics protein chemistry nuclear magnetic resonance spectroscopy antiviral research single molecule biophysics enzymes high-pressure nmr biomolecular engineering virus research protein assembly protein refolding molecular structure biophysical review protein modeling conformational studies general virology peptide science peptides magnetic resonance structure-function enzyme kinetics molecular virology rna biology membrane transport computational biophysics nmr spectroscopy biological macromolecules clinical microbiology raman spectroscopy genome biology high hydrostatic pressure antiviral drug development magnetic resonance spectroscopy viral structural protein residual stress viral genetics internal cavities high pressure disordered proteins membrane proximal regions genome-wide discovery mammalian biology supramolecular assemblies peptide engineering peptide synthesis peptide library supramolecular chemistry protein mass spectrometry antiviral therapy viral oncology virus-host interactions structural bioinformatics solid-state nmr spectroscopy protein x-ray crystallography structural plasticity pressure unfolding bulk water resemble random coil rdc measurements notch receptor volume change exposed surface area pressure-induced unfolding pressure denaturation protein evolution systems biology protein misfolding

Notable Scholarly Works

Notable Federal Grants

Collaborators

Elife Assessment: Differential Conformational Dynamics in Two Type-a Rna-Binding Domains Drive the Double-Stranded Rna Recognition and Binding. (2024)

Julien Roche

differential conformational dynamicstype-a rna-binding domainsmolecular biologydouble-stranded rna recognition

Elife Assessment: One N-Glycan Regulates Natural Killer Cell Antibody-Dependent Cell-Mediated Cytotoxicity and Modulates Fc γ Receptor Iiia/Cd16A Structure. (2024)

Julien Roche

immunologyg protein-coupled receptorreceptorscell signalingmolecular immunologymolecular biologyimmune responsescell biology

Elife Assessment: Unanticipated Mechanisms of Covalent Inhibitor and Synthetic Ligand Cobinding to Pparγ. (2024)

Julien Roche

pharmacologymechanisms of actionunanticipated mechanismssynthetic ligandcovalent inhibitor

Elucidation of the Mechanisms of Inter-Domain Coupling in the Monomeric State of Enzyme I by High-Pressure Nmr. Journal of Molecular Biology (2024)

Sergey L. SedinkinJulien RocheVincenzo Venditti

biophysicshigh-pressure nmrmonomeric stateenzymesmolecular biologystructural biologynuclear magnetic resonanceprotein scienceinter-domain couplingbiochemistry

Placing a Full Protein Library Under Pressure. Physics (2024)

Julien Roche

physicsbiophysicsprotein scienceprotein structurefull proteinprotein modeling

Thermodynamic Coupling of the Tandem Rrm Domains of Hnrnp A1 Underlie Its Pleiotropic Rna Binding Functions. Science Advances (2024)

Jeffrey D. LevengoodDavit PotoyanSrinivasa PenumutchuAbhishek KumarQianzi ZhouYiqing WangAlexandar L. HansenSebla KutluayJulien RocheBlanton S. Tolbert

biophysicstandem rrm domainsthermodynamic couplingprotein structurescience advancemolecular biologyrna biologybiochemistry

Abstract 1750: The C. Elegans Pvd Dendrite Branching Receptor Hpo-30 Regulates Actin Polymerization Through Two Distinct Mechanisms. Journal of Biological Chemistry (2023)

Daniel KramerHeidy Narvaez-OrtizRebecca ShiKang ShenJulien RocheBrad Nolen

functional modificationreceptorsgene expressionsignaling pathwaysbiomolecular interactionsdistinct mechanismscell signalinggeneticsmolecular regulationreceptor (biochemistry)molecular biologybiological chemistrysignal transductionprotein sciencemembrane biologymolecular physiologybiochemistry

Conformational Landscape of the Transcription Factor Atf4 is Dominated by Disordered-Mediated Inter-Domain Coupling. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Urval PatelSteven SiangDavit PotoyanJulien Roche

systems biologygeneticstranscription factorsdisordered-mediated inter-domain couplingmolecular biologyconformational landscapeprotein science

Evidence of Disrupted-in Schizophrenia 1 (Disc1) as an Arsenic Binding Protein and Implications Regarding Its Role as a Translational Activator. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Muneaki WatanabeTung Mei KhuGrant WarrenJuyoung ShinCharles E. StewartJulien Roche

schizophreniaarsenic binding proteingeneticspsychiatrytranslational activatorneuroscience

The Intrinsically Disordered Cytoplasmic Tail of a Dendrite Branching Receptor Uses Two Distinct Mechanisms to Regulate the Actin Cytoskeleton. eLife (2023)

Daniel A KramerHeidy Y Narvaez-OrtizUrval PatelRebecca ShiKang ShenBrad J NolenJulien RocheBaoyu Chen

actin cytoskeletondistinct mechanismsgeneticsdisordered cytoplasmic taildendrite branching receptormembrane biologystructural biologyprotein scienceneuroscienceneuroanatomycell biology

1
2
3
4
5
6
7
10 / page

Julien Roche

Associate Professor

Iowa State University

Affiliations

College of Liberal Arts and Sciences

Biochemistry, Biophysics, and Molecular Biology

College of Agriculture and Life Sciences

Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology

Julien Roche is currently serving as a Biochemistry, Biophysics, And Molecular Biology Associate Professor at Iowa State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Julien Roche

Iowa State University

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Elife Assessment: Differential Conformational Dynamics in Two Type-a Rna-Binding Domains Drive the Double-Stranded Rna Recognition and Binding. (2024)

Julien Roche

differential conformational dynamicstype-a rna-binding domainsmolecular biologydouble-stranded rna recognition

Elife Assessment: One N-Glycan Regulates Natural Killer Cell Antibody-Dependent Cell-Mediated Cytotoxicity and Modulates Fc γ Receptor Iiia/Cd16A Structure. (2024)

Julien Roche

immunologyg protein-coupled receptorreceptorscell signalingmolecular immunologymolecular biologyimmune responsescell biology

Elife Assessment: Unanticipated Mechanisms of Covalent Inhibitor and Synthetic Ligand Cobinding to Pparγ. (2024)

Julien Roche

pharmacologymechanisms of actionunanticipated mechanismssynthetic ligandcovalent inhibitor

Elucidation of the Mechanisms of Inter-Domain Coupling in the Monomeric State of Enzyme I by High-Pressure Nmr. Journal of Molecular Biology (2024)

Sergey L. SedinkinJulien RocheVincenzo Venditti

biophysicshigh-pressure nmrmonomeric stateenzymesmolecular biologystructural biologynuclear magnetic resonanceprotein scienceinter-domain couplingbiochemistry

Placing a Full Protein Library Under Pressure. Physics (2024)

Julien Roche

physicsbiophysicsprotein scienceprotein structurefull proteinprotein modeling

Thermodynamic Coupling of the Tandem Rrm Domains of Hnrnp A1 Underlie Its Pleiotropic Rna Binding Functions. Science Advances (2024)

Jeffrey D. LevengoodDavit PotoyanSrinivasa PenumutchuAbhishek KumarQianzi ZhouYiqing WangAlexandar L. HansenSebla KutluayJulien RocheBlanton S. Tolbert

biophysicstandem rrm domainsthermodynamic couplingprotein structurescience advancemolecular biologyrna biologybiochemistry

Abstract 1750: The C. Elegans Pvd Dendrite Branching Receptor Hpo-30 Regulates Actin Polymerization Through Two Distinct Mechanisms. Journal of Biological Chemistry (2023)

Daniel KramerHeidy Narvaez-OrtizRebecca ShiKang ShenJulien RocheBrad Nolen

Conformational Landscape of the Transcription Factor Atf4 is Dominated by Disordered-Mediated Inter-Domain Coupling. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Urval PatelSteven SiangDavit PotoyanJulien Roche

systems biologygeneticstranscription factorsdisordered-mediated inter-domain couplingmolecular biologyconformational landscapeprotein science

Evidence of Disrupted-in Schizophrenia 1 (Disc1) as an Arsenic Binding Protein and Implications Regarding Its Role as a Translational Activator. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Muneaki WatanabeTung Mei KhuGrant WarrenJuyoung ShinCharles E. StewartJulien Roche

schizophreniaarsenic binding proteingeneticspsychiatrytranslational activatorneuroscience

The Intrinsically Disordered Cytoplasmic Tail of a Dendrite Branching Receptor Uses Two Distinct Mechanisms to Regulate the Actin Cytoskeleton. eLife (2023)

Daniel A KramerHeidy Y Narvaez-OrtizUrval PatelRebecca ShiKang ShenBrad J NolenJulien RocheBaoyu Chen

actin cytoskeletondistinct mechanismsgeneticsdisordered cytoplasmic taildendrite branching receptormembrane biologystructural biologyprotein scienceneuroscienceneuroanatomycell biology

1
2
3
4
5
6
7
10 / page

Similar Faculty Members

Elisar J. Barbar

Institution

Oregon State University

molecular biology

nuclear magnetic resonance spectroscopy

Mahmoud Moradi

Institution

University of Arkansas

computational molecular biophysics

nonequilibrium statistical mechanics

Alex Holehouse

Institution

Washington University in St. Louis

self-assembly

protein phase separation

Matthias Buck

Institution

Case Western Reserve University

protein-membrane interactions

molecular pathway

Chunyu Wang

Institution

Rensselaer Polytechnic Institute

drug target

cancer research

Prem Chapagain

Institution

Florida International University

molecular docking

protein structural dynamics

Daniel Zuckerman

Institution

Oregon State University

biosystems

theoretical biology

Elizabeth Komives

Institution

University of California, San Diego

protein modeling

biomolecular structure

Diwakar Shukla

Institution

University of Illinois Urbana-Champaign

molecular design

molecular science

Wayne Hubbell

Institution

University of California, Los Angeles

protein science

structural biology

Similar Faculty Members

Elisar J. Barbar

Institution

Oregon State University

molecular biology

nuclear magnetic resonance spectroscopy

Mahmoud Moradi

Institution

University of Arkansas

computational molecular biophysics

nonequilibrium statistical mechanics

Alex Holehouse

Institution

Washington University in St. Louis

self-assembly

protein phase separation

Matthias Buck

Institution

Case Western Reserve University

protein-membrane interactions

molecular pathway

Chunyu Wang

Institution

Rensselaer Polytechnic Institute

drug target

cancer research

Prem Chapagain

Institution

Florida International University

molecular docking

protein structural dynamics

Daniel Zuckerman

Institution

Oregon State University

biosystems

theoretical biology

Elizabeth Komives

Institution

University of California, San Diego

protein modeling

biomolecular structure

Diwakar Shukla

Institution

University of Illinois Urbana-Champaign

molecular design

molecular science

Wayne Hubbell

Institution

University of California, Los Angeles

protein science

structural biology