Faculty

Institution

Unit

Venue

Wayne Hubbell

University of California, Los Angeles

Affiliations

the College

Molecular Biology Institute (mbi)

NoneWayne Hubbell is currently serving as a Molecular Biology Institute (Mbi) faculty at University of California, Los Angeles.

Honors

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Experiences

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Education

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Wayne Hubbell

University of California, Los Angeles

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protein science structural biology biophysics molecular biology protein structure biochemistry neuroscience membrane biology molecular biophysics enzymes structural molecular biology biomolecular structure protein chemistry conformational studies site-directed spin labeling biophysical chemistry experimental biophysics membranes protein engineering lactose permease membrane science biological chemistry biochemical sciences protein function spin-labeled proteins magnetic resonance molecular physiology single molecule biophysics molecular science mammalian biology biomolecular interactions proteinlipid interaction molecular structure structural chemistry avian biology protein nmr lipid science vision research escherichia coli medicinal research redox biology receptor (biochemistry) biological inorganic chemistry membrane transport protein transport g protein-coupled receptor surface reactivity functional modification structure-function enzyme kinetics electroanalytical chemistry protein assembly structural bioinformatics electron paramagnetic resonance molecular substrates conformational changes structural features spin dynamics bacteriology human sciences molecular docking membrane permeation photoreceptor cells antibody engineering microbial physiology light-dependent changes physiological temperatures nitroxide motion helix vii bovine rhodopsin transducin activation sulfhydryl groups saturation recovery epr conformational dynamics protein phosphorylation spin phenomenon spin-labeled side chains

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Pressure-Jump Epr System to Monitor Millisecond Conformational Exchange Rates of Spin-Labeled Proteins. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Julian D. GrosskopfJason W. SidabrasChristian AltenbachJim R. AndersonRichard R. MettRobert A. StrangewayJames S. HydeWayne L. HubbellMichael T. Lerch

biophysicspressure-jump epr systemmolecular biologystructural biologyprotein sciencespin-labeled proteins

A Pressure‐Jump Epr System to Monitor Millisecond Conformational Exchange Rates of Spin‐Labeled Proteins. Protein Science (2024)

Julian D. GrosskopfJason W. SidabrasChristian AltenbachJim R. AndersonRichard R. MettRobert A. StrangewayJames S. HydeWayne L. HubbellMichael T. Lerch

protein structureprotein sciencebiophysicsspin-labeled proteins

Ligand Efficacy Modulates Conformational Dynamics of the µ-Opioid Receptor. Nature (2024)

Jiawei ZhaoMatthias ElgetiEvan S. O’BrienCecília P. SárAmal EI DaibaniJie HengXiaoou SunElizabeth WhiteTao CheWayne L. HubbellBrian K. KobilkaChunlai Chen

immunologyreceptorspharmacologyligand efficacyneuropharmacologyu-opioid receptorprotein scienceneuroscienceconformational dynamics

A Highly Ordered Nitroxide Side Chain for Distance Mapping and Monitoring Slow Structural Fluctuations in Proteins. Applied Magnetic Resonance (2023)

Mengzhen ChenTamás KálaiDuilio CascioMichael D. BridgesJulian P. WhiteleggeMatthias ElgetiWayne L. Hubbell

biophysicsprotein structurestructural biologyapplied physicsprotein scienceneurosciencedistance mapping

Conformational Dynamics of the μ-Opioid Receptor Determine Ligand Intrinsic Efficacy. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Jiawei ZhaoMatthias ElgetiEvan S. O’BrienCecília P. SárAmal EI DaibaniJie HengXiaoou SunTao CheWayne L. HubbellBrian K. KobilkaChunlai Chen

biophysicspharmacologyneuropharmacologystructural biologyneuroscienceconformational dynamics

Conformational Flexibility of Hiv-1 Envelope Glycoproteins Modulates Transmitted / Founder Sensitivity to Broadly Neutralizing Antibodies. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Durgadevi ParthasarathyKarunakar Reddy PothulaKim-Marie A. DamSneha RatnapriyaHéctor Cervera BenetRuth ParsonsXiao HuangSalam SammourKatarzyna JanowskaMiranda HarrisSamuel SaccoJoseph SodroskiMichael D. BridgesWayne L. HubbellPriyamvada AcharyaAlon Herschhorn

clinical microbiologygeneral virologyviral pathogenesisantibody engineeringvaccinationinfectious diseaseshivantiviral researchvirus-host interactionsantiviral responsesimmune responsesmicrobial pathogenesisconformational flexibilityhuman retrovirusimmunologyvirus researchvirologymolecular biologymedicinal researchneutralizing antibodies

Membrane Potential Accelerates Sugar Uptake by Stabilizing the Outward Facing Conformation of the Na/Glucose Symporter Vsglt. Nature Communications (2023)

Farha KhanMatthias ElgetiSamuel GrandfieldAviv PazFiona B. NaughtonFrank V. MarcolineThorsten AlthoffNatalia ErmolovaErnest M. WrightWayne L. HubbellMichael GrabeJeff Abramson

physiologypharmacologycellular physiologysugar uptakemembranesmembrane scienceprotein sciencesurface reactivitymembrane biologymembrane potentialcell biology

Conformational Diversity and Contraction of the Denatured State Ensemble of a Helical Membrane Protein. Biophysical Journal (2022)

Tobin R. SosnickKristen A. GaffneyRuiqiong GuoMichael D. BridgesDaoyang ChenFathima Shaima MuhammedNazaarMiyeon KimZhongyu YangAnthony L. SchilmillerNabil F. FarukXiangda PengA.D. JonesLiangliang SunWayne L. HubbellHeedeok Hong

biophysicsconformational diversitydenatured state ensemblemembrane proteinshelical membrane protein

Neutralizing Antibodies Induced in Immunized Macaques Recognize the Cd4-Binding Site on an Occluded-Open Hiv-1 Envelope Trimer. Nature Communications (2022)

Zhi YangKim-Marie A. DamMichael D. BridgesMagnus A. G. HoffmannAndrew T. DeLaitschHarry B. GristickAmelia EscolanoRajeev GautamMalcolm A. MartinMichel C. NussenzweigWayne L. HubbellPamela J. Bjorkman

immunologyhivvirus researchimmunochemistryvirologyantibody engineeringimmunized macaquesinfectious diseasesviral diagnostics

Deer Analysis of Gpcr Conformational Heterogeneity. Biomolecules (2021)

Matthias ElgetiWayne L. Hubbell

materials sciencebiophysicsconformational studiesmolecular biologydeer analysisstructural biologygpcr conformational heterogeneity

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Wayne Hubbell

University of California, Los Angeles

Affiliations

the College

Molecular Biology Institute (mbi)

NoneWayne Hubbell is currently serving as a Molecular Biology Institute (Mbi) faculty at University of California, Los Angeles.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Wayne Hubbell

University of California, Los Angeles

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Pressure-Jump Epr System to Monitor Millisecond Conformational Exchange Rates of Spin-Labeled Proteins. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Julian D. GrosskopfJason W. SidabrasChristian AltenbachJim R. AndersonRichard R. MettRobert A. StrangewayJames S. HydeWayne L. HubbellMichael T. Lerch

biophysicspressure-jump epr systemmolecular biologystructural biologyprotein sciencespin-labeled proteins

A Pressure‐Jump Epr System to Monitor Millisecond Conformational Exchange Rates of Spin‐Labeled Proteins. Protein Science (2024)

Julian D. GrosskopfJason W. SidabrasChristian AltenbachJim R. AndersonRichard R. MettRobert A. StrangewayJames S. HydeWayne L. HubbellMichael T. Lerch

protein structureprotein sciencebiophysicsspin-labeled proteins

Ligand Efficacy Modulates Conformational Dynamics of the µ-Opioid Receptor. Nature (2024)

Jiawei ZhaoMatthias ElgetiEvan S. O’BrienCecília P. SárAmal EI DaibaniJie HengXiaoou SunElizabeth WhiteTao CheWayne L. HubbellBrian K. KobilkaChunlai Chen

immunologyreceptorspharmacologyligand efficacyneuropharmacologyu-opioid receptorprotein scienceneuroscienceconformational dynamics

A Highly Ordered Nitroxide Side Chain for Distance Mapping and Monitoring Slow Structural Fluctuations in Proteins. Applied Magnetic Resonance (2023)

Mengzhen ChenTamás KálaiDuilio CascioMichael D. BridgesJulian P. WhiteleggeMatthias ElgetiWayne L. Hubbell

biophysicsprotein structurestructural biologyapplied physicsprotein scienceneurosciencedistance mapping

Conformational Dynamics of the μ-Opioid Receptor Determine Ligand Intrinsic Efficacy. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Jiawei ZhaoMatthias ElgetiEvan S. O’BrienCecília P. SárAmal EI DaibaniJie HengXiaoou SunTao CheWayne L. HubbellBrian K. KobilkaChunlai Chen

biophysicspharmacologyneuropharmacologystructural biologyneuroscienceconformational dynamics

Conformational Flexibility of Hiv-1 Envelope Glycoproteins Modulates Transmitted / Founder Sensitivity to Broadly Neutralizing Antibodies. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Membrane Potential Accelerates Sugar Uptake by Stabilizing the Outward Facing Conformation of the Na/Glucose Symporter Vsglt. Nature Communications (2023)

Farha KhanMatthias ElgetiSamuel GrandfieldAviv PazFiona B. NaughtonFrank V. MarcolineThorsten AlthoffNatalia ErmolovaErnest M. WrightWayne L. HubbellMichael GrabeJeff Abramson

physiologypharmacologycellular physiologysugar uptakemembranesmembrane scienceprotein sciencesurface reactivitymembrane biologymembrane potentialcell biology

Conformational Diversity and Contraction of the Denatured State Ensemble of a Helical Membrane Protein. Biophysical Journal (2022)

biophysicsconformational diversitydenatured state ensemblemembrane proteinshelical membrane protein

Neutralizing Antibodies Induced in Immunized Macaques Recognize the Cd4-Binding Site on an Occluded-Open Hiv-1 Envelope Trimer. Nature Communications (2022)

Zhi YangKim-Marie A. DamMichael D. BridgesMagnus A. G. HoffmannAndrew T. DeLaitschHarry B. GristickAmelia EscolanoRajeev GautamMalcolm A. MartinMichel C. NussenzweigWayne L. HubbellPamela J. Bjorkman

immunologyhivvirus researchimmunochemistryvirologyantibody engineeringimmunized macaquesinfectious diseasesviral diagnostics

Deer Analysis of Gpcr Conformational Heterogeneity. Biomolecules (2021)

Matthias ElgetiWayne L. Hubbell

materials sciencebiophysicsconformational studiesmolecular biologydeer analysisstructural biologygpcr conformational heterogeneity

1
2
3
4
5
30
10 / page

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