Faculty

Institution

Unit

Venue

Elisar J. Barbar

Professor

Oregon State University

Affiliations

College of Science

Department of Biochemistry and Biophysics

Elisar J. Barbar is currently serving as a College Of Science Professor at Oregon State University.

Honors

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Experiences

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Education

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Elisar J. Barbar

Oregon State University

Professor

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molecular biology protein science structural biology biophysics biochemistry protein structure biomolecular structure structural molecular biology genetics protein folding protein assembly gene expression molecular structure biological chemistry membrane biology molecular cell biology biomolecular interactions nuclear magnetic resonance molecular and cellular biology multi-protein assembly enzymes protein function virus research molecular regulation protein nmr dynein intermediate chain viral genetics rna biology mammalian biology protein chemistry molecular physiology enzyme inhibition viral structural protein dynein light chain general virology biochemical sciences protein misfolding cytoplasmic dynein nucleic acids molecular virology virus-host interactions genome biology redox biology transcription regulation molecular recognition protein phosphorylation intermediate chain avian biology molecular complexes supramolecular assemblies protein genetics protein synthesis nmr characterization molecular diversity pharmaceutical chemistry molecular evidence biological function gene regulation biochemical interaction integrative biology sequence assembly gene recognition cell-matrix interactions cellular enzymology rrna elements preribosome maturation assembly factors multivalent binding disordered transcription factor dynamic structure bioconjugation diverse protein networks nicotiana tabacum kxtqt-motif peptides common site light chain nuclear magnetic resonance spectroscopy protein complexes

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2025 - Improving Parameter Inference for Isothermal Titration Calorimetry Using Bayesian Analysis on Multiple Datasets. Biophysical Journal (2025)

multivariate calibrationcalorimetric methodisothermal titration calorimetrystatistical inferencebiostatisticsbayesian analysisthermodynamicsthermodynamic modellingdata scienceparameter inferencemultiple datasetsstatistical models

Dynamic Interactions of Dimeric Hub Proteins Underlie Their Diverse Functions and Structures: A Comparative Analysis of 14-3-3 and Lc8. Journal of Biological Chemistry (2025)

biological macromoleculesprotein assemblyprotein functionprotein structure predictionprotein structurebiomolecular structuredimeric hub proteinscomparative analysisdiverse functionsmolecular biologystructural molecular biologystructural bioinformaticsbiochemistrystructural biologyprotein sciencemulti-protein assemblyprotein folding

Nmr Approaches to Identify Transient Structure and Interactions of Intrinsically Disordered Dynein Intermediate Chain. (2025)

molecular biophysicsbiophysicssingle molecule biophysicsprotein structuremolecular structureprotein nmrconformational studiestransient structuremolecular biologybiomolecular structurenuclear magnetic resonancenmr approachesbiochemistry

Successful Prediction of Lc8 Binding to Intrinsically Disordered Proteins Sheds Light on Alphafold’s Black Box. Frontiers in Molecular Biosciences (2025)

protein assemblyproteomicsprotein functionprotein structure predictionprotein modelingblack boxprotein misfoldingprotein structurebiomolecular structuremolecular biologystructural molecular biologybiochemistrystructural biologyprotein sciencealphafold ’protein foldingsuccessful prediction

The Bpti Story: From the Slow Exchange Core to Intrinsically Disordered Proteins. International Journal of Peptide Research and Therapeutics (2025)

slow exchange corebiophysicsprotein chemistryprotein assemblyprotein misfoldingprotein structurebpti storybiomolecular structureintrinsically disordered proteinsmolecular biologystructural molecular biologystructural biologyprotein scienceprotein foldingbiochemistry

Walking the Tightrope: Balancing Opposing Cooperativities as an Operating Principle in Dynein Assembly. bioRxiv (Cold Spring Harbor Laboratory) (2025)

physicssymmetryquantum theoryquantum sciencecondensed matter physicsquantum mechanicscondensed matternegative cooperativitypolybivalent complexmathematical physicsquantum mechanical propertiesquantum materialspartial bound statemathematics

Weak Motifs, Strong Complex: Kank1 Uses Cooperative Multivalency With the Hub-Protein Lc8 to Bridge Cytoskeletal Complexes. bioRxiv (Cold Spring Harbor Laboratory) (2025)

biological macromoleculesprotein functioncell signalingweak motifscell biologybiomolecular interactionscytoskeletonmolecular cell biologybiomolecular structureprotein sciencemolecular and cellular biologyprotein designsystems biologystrong complexcooperative multivalencymolecular biologystructural molecular biologysignal transductionmulti-protein assembly

Investigating Cooperativity in the Lc8 Protein Hub via Molecular Dynamics Simulations. Biophysical Journal (2024)

Shelby D. SantosElisar J. BarbarDaniel M. Zuckerman

computational biophysicsmolecular dynamics simulationsmolecular biophysicsbiophysicssystems biology

Lc8 Enhances 53Bp1 Foci Through Heterogeneous Bridging of 53Bp1 Oligomers. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jesse HoweDouglas WalkerKyle TenglerMaya SonpatkiPatrick N ReardonJustin W.C. LeungElisar J Barbar

biophysicsprotein assemblyself-assemblyheterogeneous bridgingmolecular biologyprotein sciencelarge scale structurebiochemistry

Phosphorylation in the Ser/Arg-Rich Region of the Nucleocapsid of Sars-Cov-2 Regulates Phase Separation by Inhibiting Self-Association of a Distant Helix. Journal of Biological Chemistry (2024)

Hannah StuwePatrick N. ReardonZhen YuSahana ShahKaitlyn HughesElisar J. Barbar

virus researchgene expressionsars-cov-2geneticsmolecular and cellular biologyviral geneticsprotein phosphorylationdistant helixmolecular biologybiological chemistrycell and molecular biologystructural molecular biologystructural biologyviral structural proteinprotein sciencemolecular physiologybiochemistry

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Elisar J. Barbar

Professor

Oregon State University

Affiliations

College of Science

Department of Biochemistry and Biophysics

Elisar J. Barbar is currently serving as a College Of Science Professor at Oregon State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Elisar J. Barbar

Oregon State University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2025 - Improving Parameter Inference for Isothermal Titration Calorimetry Using Bayesian Analysis on Multiple Datasets. Biophysical Journal (2025)

Dynamic Interactions of Dimeric Hub Proteins Underlie Their Diverse Functions and Structures: A Comparative Analysis of 14-3-3 and Lc8. Journal of Biological Chemistry (2025)

Nmr Approaches to Identify Transient Structure and Interactions of Intrinsically Disordered Dynein Intermediate Chain. (2025)

Successful Prediction of Lc8 Binding to Intrinsically Disordered Proteins Sheds Light on Alphafold’s Black Box. Frontiers in Molecular Biosciences (2025)

The Bpti Story: From the Slow Exchange Core to Intrinsically Disordered Proteins. International Journal of Peptide Research and Therapeutics (2025)

Walking the Tightrope: Balancing Opposing Cooperativities as an Operating Principle in Dynein Assembly. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Weak Motifs, Strong Complex: Kank1 Uses Cooperative Multivalency With the Hub-Protein Lc8 to Bridge Cytoskeletal Complexes. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Investigating Cooperativity in the Lc8 Protein Hub via Molecular Dynamics Simulations. Biophysical Journal (2024)

Shelby D. SantosElisar J. BarbarDaniel M. Zuckerman

computational biophysicsmolecular dynamics simulationsmolecular biophysicsbiophysicssystems biology

Lc8 Enhances 53Bp1 Foci Through Heterogeneous Bridging of 53Bp1 Oligomers. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jesse HoweDouglas WalkerKyle TenglerMaya SonpatkiPatrick N ReardonJustin W.C. LeungElisar J Barbar

biophysicsprotein assemblyself-assemblyheterogeneous bridgingmolecular biologyprotein sciencelarge scale structurebiochemistry

Phosphorylation in the Ser/Arg-Rich Region of the Nucleocapsid of Sars-Cov-2 Regulates Phase Separation by Inhibiting Self-Association of a Distant Helix. Journal of Biological Chemistry (2024)

Hannah StuwePatrick N. ReardonZhen YuSahana ShahKaitlyn HughesElisar J. Barbar

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self-assembly

protein phase separation

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