Faculty

Institution

Unit

Venue

Linda Jen-Jacobson

Professor Emerita

University of Pittsburgh

Affiliations

Kenneth P. Dietrich School of Arts and Sciences

Biological Sciences

Dental Medicine

Department of Diagnostic Sciences

Linda Jen-jacobson is currently serving as a Biological Sciences Professor Emerita at University of Pittsburgh.

Honors

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Experiences

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Education

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Linda Jen-Jacobson

University of Pittsburgh

Professor Emerita

You can click a keyword to filter the displayed items

molecular biology genetics biophysics structural biology biochemistry protein science molecular genetics molecular biophysics ecori endonuclease dna repair genome biology bioinformatics nucleic acids protein structure genomics biomolecular structure structural molecular biology proteomics molecular science molecular structure redox biology protein synthesis experimental biophysics biological chemistry molecular ecology transition metal chemistry coordination chemistry biomolecular interactions molecular recognition rna biology structural bioinformatics sequence analysis mutagenesis oligonucleotides protein genetics bacteriology chiral phosphorothioates site-specific protein translational initiation escherichia coli plo biology enzyme inhibition scientometrics theoretical biology inhibitory activity enzyme catalysis enzyme specificity biocatalysis biological inorganic chemistry supramolecular chemistry lab-on-a-chip biochemical genetics sequence alignment genome analysis epigenomics nematology protein modeling dna analysis key site molecular substrates gene structure animal genetics gene function polymerization kinetics genome instability energetic basis eco ri endonuclease dna interaction crystalline complex thermodynamic strategies single-molecule imaging concentration-dependent exchange single-stranded dna transition state specific binding ecorv endonuclease protein nmr nuclear magnetic resonance spectroscopy protein-dna complexes nuclear magnetic resonance protein folding biomolecular analysis

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cu2+-Based Distance Measurements by Pulsed Epr Provide Distance Constraints for Dna Backbone Conformations in Solution. Nucleic Acids Research (2020)

Shreya GhoshMatthew J LawlessHanna J BrubakerKevin SingewaldMichael R KurpiewskiLinda Jen-JacobsonSunil Saxena

biophysicspulsed eprgeneticsnucleic acidsbioinformaticsdna backbone conformationsdistance constraintsgenome biologymolecular biologystructural biology

Backbone Assignments and Ilv Methyl Assignments for Ecorv Bound to 16-Mer Double Stranded Dna (Gcaaagatatctttcg) Without Lu3+. Journal of Back and Musculoskeletal Rehabilitation (2018)

Kaustubh SinhaSahil SanganiGordon RuleLinda Jen-Jacobson

geneticsmusculoskeletal scienceorthopaedic surgerymusculoskeletal researchecorv boundrehabilitationilv methyl assignmentsbackbone assignmentsstructural biology

Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein–Dna Complex. Biochemistry (2016)

Kaustubh SinhaSahil S. SanganiAndrew D. KehrGordon S. RuleLinda Jen-Jacobson

redox biologybiochemistrymolecular biologytransition metal chemistrymetal ion bindingstructural biology

Restriction Cascade Exponential Amplification (Rcea) Assay With an Attomolar Detection Limit: A Novel, Highly Specific, Isothermal Alternative to Qpcr. Scientific Reports (2015)

Andrey L. GhindilisMaria W. SmithHolly M. SimonIhab A. SeoudiNina S. YazvenkoIain A. MurrayXiaoqing FuKenneth SmithLinda Jen-JacobsonShuang-yong Xu

molecular biologymolecular diagnosticshealth sciencesattomolar detection limit

Complex Temperature Dependent Equilibria Dictate Dna Polymerase Exchange Processes During Synthesis. Biophysical Journal (2014)

Michael A. TrakselisRobert J. BauerHsiang-Kai LinLinda Jen-Jacobson

biophysicsmolecular biophysicssystems biologymembrane biologymolecular biologyexperimental biophysicsbiophysical chemistrymolecular physiology

Concentration-Dependent Exchange of Replication Protein a on Single-Stranded Dna Revealed by Single-Molecule Imaging. PLoS ONE (2014)

Bryan GibbLing F. YeStephanie C. GergoudisYoungHo KwonHengyao NiuPatrick SungEric C. Greene

biophysicsgeneticssingle-stranded dnaplo biologyproteomicsmolecular biologysingle-molecule imagingconcentration-dependent exchange

Insights Into Copper Coordination in the Ecori–Dna Complex by Esr Spectroscopy. Molecular Physics (2014)

Ming JiLikun TanLinda Jen-JacobsonSunil Saxena

biophysicscopper coordinationinorganic chemistryecori-dna complexmolecular biologyesr spectroscopy

Divide and Conquer is Always Best: Sensitivity of Methyl Correlation Experiments. Journal of Biomolecular NMR (2013)

Kaustubh SinhaLinda Jen-JacobsonGordon S. Rule

surface sciencemethyl correlation experimentsbiomolecular engineeringbiochemistrymolecular biology

Sensitive Cu 2+ –Cu 2+ Distance Measurements in a Protein–Dna Complex by Double-Quantum Coherence Esr. The Journal of Physical Chemistry B (2013)

Sharon RuthsteinMing JiPreeti MehtaLinda Jen-JacobsonSunil Saxena

biophysicsbiochemistryphysical chemistrydouble-quantum coherence esrbiophysical chemistry

Thermodynamic and Structural Basis for Relaxation of Specificity in Protein–Dna Recognition. Journal of Molecular Biology (2013)

Paul J. SapienzaTianyi NiuMichael R. KurpiewskiArabela GrigorescuLinda Jen-Jacobson

biophysicsprotein sciencebiochemistrystructural basismolecular biologyprotein-dna recognitionstructural biology

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Linda Jen-Jacobson

Professor Emerita

University of Pittsburgh

Affiliations

Kenneth P. Dietrich School of Arts and Sciences

Biological Sciences

Dental Medicine

Department of Diagnostic Sciences

Linda Jen-jacobson is currently serving as a Biological Sciences Professor Emerita at University of Pittsburgh.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Linda Jen-Jacobson

University of Pittsburgh

Professor Emerita

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cu2+-Based Distance Measurements by Pulsed Epr Provide Distance Constraints for Dna Backbone Conformations in Solution. Nucleic Acids Research (2020)

Shreya GhoshMatthew J LawlessHanna J BrubakerKevin SingewaldMichael R KurpiewskiLinda Jen-JacobsonSunil Saxena

biophysicspulsed eprgeneticsnucleic acidsbioinformaticsdna backbone conformationsdistance constraintsgenome biologymolecular biologystructural biology

Backbone Assignments and Ilv Methyl Assignments for Ecorv Bound to 16-Mer Double Stranded Dna (Gcaaagatatctttcg) Without Lu3+. Journal of Back and Musculoskeletal Rehabilitation (2018)

Kaustubh SinhaSahil SanganiGordon RuleLinda Jen-Jacobson

geneticsmusculoskeletal scienceorthopaedic surgerymusculoskeletal researchecorv boundrehabilitationilv methyl assignmentsbackbone assignmentsstructural biology

Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein–Dna Complex. Biochemistry (2016)

Kaustubh SinhaSahil S. SanganiAndrew D. KehrGordon S. RuleLinda Jen-Jacobson

redox biologybiochemistrymolecular biologytransition metal chemistrymetal ion bindingstructural biology

Restriction Cascade Exponential Amplification (Rcea) Assay With an Attomolar Detection Limit: A Novel, Highly Specific, Isothermal Alternative to Qpcr. Scientific Reports (2015)

Andrey L. GhindilisMaria W. SmithHolly M. SimonIhab A. SeoudiNina S. YazvenkoIain A. MurrayXiaoqing FuKenneth SmithLinda Jen-JacobsonShuang-yong Xu

molecular biologymolecular diagnosticshealth sciencesattomolar detection limit

Complex Temperature Dependent Equilibria Dictate Dna Polymerase Exchange Processes During Synthesis. Biophysical Journal (2014)

Michael A. TrakselisRobert J. BauerHsiang-Kai LinLinda Jen-Jacobson

biophysicsmolecular biophysicssystems biologymembrane biologymolecular biologyexperimental biophysicsbiophysical chemistrymolecular physiology

Concentration-Dependent Exchange of Replication Protein a on Single-Stranded Dna Revealed by Single-Molecule Imaging. PLoS ONE (2014)

Bryan GibbLing F. YeStephanie C. GergoudisYoungHo KwonHengyao NiuPatrick SungEric C. Greene

biophysicsgeneticssingle-stranded dnaplo biologyproteomicsmolecular biologysingle-molecule imagingconcentration-dependent exchange

Insights Into Copper Coordination in the Ecori–Dna Complex by Esr Spectroscopy. Molecular Physics (2014)

Ming JiLikun TanLinda Jen-JacobsonSunil Saxena

biophysicscopper coordinationinorganic chemistryecori-dna complexmolecular biologyesr spectroscopy

Divide and Conquer is Always Best: Sensitivity of Methyl Correlation Experiments. Journal of Biomolecular NMR (2013)

Kaustubh SinhaLinda Jen-JacobsonGordon S. Rule

surface sciencemethyl correlation experimentsbiomolecular engineeringbiochemistrymolecular biology

Sensitive Cu 2+ –Cu 2+ Distance Measurements in a Protein–Dna Complex by Double-Quantum Coherence Esr. The Journal of Physical Chemistry B (2013)

Sharon RuthsteinMing JiPreeti MehtaLinda Jen-JacobsonSunil Saxena

biophysicsbiochemistryphysical chemistrydouble-quantum coherence esrbiophysical chemistry

Thermodynamic and Structural Basis for Relaxation of Specificity in Protein–Dna Recognition. Journal of Molecular Biology (2013)

Paul J. SapienzaTianyi NiuMichael R. KurpiewskiArabela GrigorescuLinda Jen-Jacobson

biophysicsprotein sciencebiochemistrystructural basismolecular biologyprotein-dna recognitionstructural biology

1
2
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5
6
10 / page

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Institution

University of Southern California

nucleic acid chemistry

crispr

Albert M Bobst

Institution

University of Cincinnati

molecular biology

electron paramagnetic resonance

Junji Iwahara

Institution

University of Texas Medical Branch

protein structure

biomolecular structure

Arthur Pardi

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University of Colorado Boulder

molecular informatics

molecular biophysics

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Michael A. Kennedy

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nmr spectroscopy

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Oregon State University

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Werner Braun

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Haribabu Arthanari

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nuclear magnetic resonance

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