Faculty

Institution

Unit

Venue

Michael A. Marletta

Professor of Chemistry; Professor of Molecular and Cell Biology; CH and Annie Li Chair in the Molecular Biology of Diseases

University of California, Berkeley

Affiliations

College of Letters & Science

Biological Sciences

College of Chemistry

Department of Chemistry

Biological Sciences

Molecular and Cell Biology

Michael A. Marletta is currently serving as a Biological Sciences Professor of Chemistry; Professor of Molecular and Cell Biology; CH and Annie Li Chair in the Molecular Biology of Diseases at University of California, Berkeley.

Honors

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Experiences

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Education

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Michael A. Marletta

University of California, Berkeley

Professor of Chemistry; Professor of Molecular and Cell Biology; CH and Annie Li Chair in the Molecular Biology of Diseases

You can click a keyword to filter the displayed items

biochemistry enzymes molecular biology pharmacology protein science redox biology biological chemistry membrane biology structural biology enzyme inhibition chemical biology soluble guanylate cyclase medicinal chemistry biological inorganic chemistry immunology enzyme catalysis nitric oxide biochemical sciences cell signaling signal transduction protein structure heme signaling nitrosative stress structural molecular biology reactive nitrogen species biocatalysis nitric oxide synthase free radical biology medicinal research molecular science molecular physiology molecular microbiology mammalian biology protein chemistry molecular regulation structure-function enzyme kinetics transition metal chemistry host-guest chemistry heme trafficking redox signaling polysaccharides respiratory medicine cellular biochemistry coordination chemistry microbial physiology heme homeostasis biomolecular structure redox chemistry molecular substrates heme transport functional modification polysaccharide monooxygenases neurochemistry molecular catalysis protein synthesis plant biochemistry electron transfer signaling pathways host response metalloproteins protein expression heme domain cytokines cellular enzymology endothelial dysfunction host-microbe interactions murine macrophages carbon monoxide selective inhibition h-nox family h-nox domain macrophage oxidation bovine lung cellulose degradation fungal polysaccharide monooxygenases structural basis

Notable Scholarly Works

Notable Federal Grants

Collaborators

Characterization of an No-Activated Homodimeric Soluble Guanylate Cyclase From a Choanoflagellate. Biochemistry (2025)

enzymesbiological chemistryenzyme catalysisbiochemistry

Electron Transfer in Polysaccharide Monooxygenase Catalysis. Proceedings of the National Academy of Sciences (2024)

Richard I. SaylerWilliam C. ThomasAlexander J. RoseMichael A. Marletta

catalysiselectron transferenzymesbiocatalysispolysaccharidesmolecular biologyenzyme catalysispolysaccharide monooxygenase catalysisbiochemistry

Molecular Aspects of Sgc Activation and Stimulator Function. (2024)

Michael MarlettaKimberly HoughtonWilliam ThomasYang Wu

immunologysgc activationcell signalingmolecular neurobiologymolecular biologystimulator functiontumor biologyneuroscience

Second-Sphere Histidine Catalytic Function in a Fungal Polysaccharide Monooxygenase. Biochemistry (2024)

Allison E. BatkaWilliam C. ThomasDan A. TudoricaRichard I. SaylerMichael A. Marletta

fungal polysaccharide monooxygenasecatalysisprotein structurebiomolecular engineeringenzymesbiocatalysismolecular biologyenzyme catalysisprotein sciencebiochemistrybiosynthesis

Allosteric Activation of Choanoflagellate Soluble Guanylate Cyclases. Acta Crystallographica Section A Foundations and Advances (2023)

William C. ThomasYang WuMichael A. Marletta

geneticsallosteric activationenzymesmolecular biologystructural molecular biologystructural chemistrystructural biologyprotein sciencex-ray crystallographycrystallographybiochemistry

Characterization of a Unique Polysaccharide Monooxygenase From the Plant Pathogen Magnaporthe Oryzae. Proceedings of the National Academy of Sciences (2023)

Alejandra Martinez-D’AltoXia YanTyler C. DetomasiRichard I. SaylerWilliam C. ThomasNicholas J. TalbotMichael A. Marletta

pathogensmolecular plant pathologyplant-pathogen interactionscarbohydrate chemistryplant biotechnologymolecular scienceplant biochemistrygeneticsenzymespolysaccharidesplant diseasemolecular biologyhost-guest chemistryplant pathologyhorticulture researchplant genomicsbiochemistrybiosynthesis

Proteases Influence Colony Aggregation Behavior in Vibrio Cholerae. Journal of Biological Chemistry (2023)

Tyler C. DetomasiAllison E. BatkaJulie S. ValastyanMolly A. HydornCharles S. CraikBonnie L. BasslerMichael A. Marletta

immunologyhost responseclinical microbiologymicrobial ecologyvirologyinfectious diseasesmicrobiologyvibrio cholerae

Role of the Coiled-Coil Domain in Allosteric Activity Regulation in Soluble Guanylate Cyclase. Biochemistry (2023)

Elizabeth C. WittenbornWilliam C. ThomasKimberly A. HoughtonErika S. WirachmanYang WuMichael A. Marletta

enzymessoluble guanylate cyclaseallosteric activity regulationcoiled-coil domainbiochemistry

A Moonlighting Function of a Chitin Polysaccharide Monooxygenase, Cwr-1, in Allorecognition in Neurospora Crassa. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Tyler C. DetomasiAdriana M. Rico-RamírezRichard I. SaylerA. Pedro GonçalvesMichael A. MarlettaN. Louise Glass

medical mycologymoonlighting functionapplied phycologyprotein sciencefungal ecologybiologyplant physiologyenzymesmolecular biologychitin polysaccharide monooxygenaseplant biochemistryindustrial mycologybotanybiochemistry

A Moonlighting Function of a Chitin Polysaccharide Monooxygenase, Cwr-1, in Neurospora Crassa Allorecognition. eLife (2022)

Tyler C DetomasiAdriana M Rico-RamírezRichard I SaylerA Pedro GonçalvesMichael A MarlettaN Louise Glass

immunologymoonlighting functionpharmacologyneurospora crassa allorecognitionenzymesmolecular biologychitin polysaccharide monooxygenasealgal researchbotany

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Michael A. Marletta

Professor of Chemistry; Professor of Molecular and Cell Biology; CH and Annie Li Chair in the Molecular Biology of Diseases

University of California, Berkeley

Affiliations

College of Letters & Science

Biological Sciences

College of Chemistry

Department of Chemistry

Biological Sciences

Molecular and Cell Biology

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Michael A. Marletta

University of California, Berkeley

Professor of Chemistry; Professor of Molecular and Cell Biology; CH and Annie Li Chair in the Molecular Biology of Diseases

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Characterization of an No-Activated Homodimeric Soluble Guanylate Cyclase From a Choanoflagellate. Biochemistry (2025)

enzymesbiological chemistryenzyme catalysisbiochemistry

Electron Transfer in Polysaccharide Monooxygenase Catalysis. Proceedings of the National Academy of Sciences (2024)

Richard I. SaylerWilliam C. ThomasAlexander J. RoseMichael A. Marletta

catalysiselectron transferenzymesbiocatalysispolysaccharidesmolecular biologyenzyme catalysispolysaccharide monooxygenase catalysisbiochemistry

Molecular Aspects of Sgc Activation and Stimulator Function. (2024)

Michael MarlettaKimberly HoughtonWilliam ThomasYang Wu

immunologysgc activationcell signalingmolecular neurobiologymolecular biologystimulator functiontumor biologyneuroscience

Second-Sphere Histidine Catalytic Function in a Fungal Polysaccharide Monooxygenase. Biochemistry (2024)

Allison E. BatkaWilliam C. ThomasDan A. TudoricaRichard I. SaylerMichael A. Marletta

fungal polysaccharide monooxygenasecatalysisprotein structurebiomolecular engineeringenzymesbiocatalysismolecular biologyenzyme catalysisprotein sciencebiochemistrybiosynthesis

Allosteric Activation of Choanoflagellate Soluble Guanylate Cyclases. Acta Crystallographica Section A Foundations and Advances (2023)

William C. ThomasYang WuMichael A. Marletta

geneticsallosteric activationenzymesmolecular biologystructural molecular biologystructural chemistrystructural biologyprotein sciencex-ray crystallographycrystallographybiochemistry

Characterization of a Unique Polysaccharide Monooxygenase From the Plant Pathogen Magnaporthe Oryzae. Proceedings of the National Academy of Sciences (2023)

Alejandra Martinez-D’AltoXia YanTyler C. DetomasiRichard I. SaylerWilliam C. ThomasNicholas J. TalbotMichael A. Marletta

Proteases Influence Colony Aggregation Behavior in Vibrio Cholerae. Journal of Biological Chemistry (2023)

Tyler C. DetomasiAllison E. BatkaJulie S. ValastyanMolly A. HydornCharles S. CraikBonnie L. BasslerMichael A. Marletta

immunologyhost responseclinical microbiologymicrobial ecologyvirologyinfectious diseasesmicrobiologyvibrio cholerae

Role of the Coiled-Coil Domain in Allosteric Activity Regulation in Soluble Guanylate Cyclase. Biochemistry (2023)

Elizabeth C. WittenbornWilliam C. ThomasKimberly A. HoughtonErika S. WirachmanYang WuMichael A. Marletta

enzymessoluble guanylate cyclaseallosteric activity regulationcoiled-coil domainbiochemistry

A Moonlighting Function of a Chitin Polysaccharide Monooxygenase, Cwr-1, in Allorecognition in Neurospora Crassa. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Tyler C. DetomasiAdriana M. Rico-RamírezRichard I. SaylerA. Pedro GonçalvesMichael A. MarlettaN. Louise Glass

A Moonlighting Function of a Chitin Polysaccharide Monooxygenase, Cwr-1, in Neurospora Crassa Allorecognition. eLife (2022)

Tyler C DetomasiAdriana M Rico-RamírezRichard I SaylerA Pedro GonçalvesMichael A MarlettaN Louise Glass

immunologymoonlighting functionpharmacologyneurospora crassa allorecognitionenzymesmolecular biologychitin polysaccharide monooxygenasealgal researchbotany

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10 / page

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