Faculty

Institution

Unit

Venue

Shahriar Mobashery

University of Notre Dame

Affiliations

College of Science

Chemistry and Biochemistry

NoneShahriar Mobashery is currently serving as a Chemistry And Biochemistry faculty at University of Notre Dame.

Honors

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Experiences

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Education

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Shahriar Mobashery

University of Notre Dame

You can click a keyword to filter the displayed items

pharmacology biochemistry microbiology enzymes molecular biology medicinal chemistry clinical microbiology protein science enzyme inhibition drug discovery structural biology protein structure applied microbiology antimicrobial resistance antibiotic resistance drug resistance biological chemistry bacteriology chemical biology structural molecular biology protein chemistry molecular microbiology enzyme catalysis pharmaceutical chemistry biomolecular structure medicinal research antimicrobial agents biological inorganic chemistry b-lactam antibiotics matrix biology pseudomonas aeruginosa pharmacotherapy structure-function enzyme kinetics bacterial cell wall biochemical sciences structural chemistry molecular structure protein function antimicrobial chemotherapy microbial genetics medical microbiology metalloproteins biological macromolecules biocatalysis antimicrobial susceptibility matrix metalloproteinases molecular science protein x-ray crystallography cell wall anti-cancer agents clinical pharmacology functional modification pharmaceutical sciences escherichia coli cell-matrix interactions drug targeting antimicrobial compounds microbial physiology methicillin-resistant staphylococcus aureus tumor targeting antibacterial agents x-ray structure structural basis structure-activity relationship active site inhibitory activity novel therapies penicillin-binding proteins induced resistance molecular catalysis catalyst activation staphylococcus aureus aminoglycoside antibiotics b-lactam resistance gram-negative bacteria carbapenem antibiotics

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bacterial Peptidoglycan as a Living Polymer. Current Opinion in Chemical Biology (2024)

Amr M El-ArabyJed F FisherShahriar Mobashery

bacterial peptidoglycanliving polymerbiochemistrychemical biologybiopolymers

Characterization of Vlde (Spr1875), a Pneumococcal Two-State L, D -Endopeptidase With a Four-Zinc Cluster in the Active Site. ACS Catalysis (2024)

Vega Miguel-RuanoIván AcebrónMijoon LeeAntonio J. Martín-GalianoCeline FretonUxía P. de JoséBalajee RamachandranFederico GagoMorten KjosDusan HesekChristophe GrangeasseLeiv Sigve HåvarsteinDaniel StraumeShahriar MobasheryJuan A. Hermoso

pathogenic bacteriamicrobiologyintermediate hosttransition metal chemistryenzyme catalysisbiochemistryactive sitemolecular biologycatalysisbacteriastructural molecular biologyenzymesprotein sciencefour-zinc cluster

Lytic Transglycosylase Slt of Pseudomonas Aeruginosa as a Periplasmic Hub Protein. Protein Science (2024)

Luis F. Avila‐CobianStefania De BenedettiHidekazu HoshinoVan T. NguyenAmr M. El‐ArabySafaa SaderDaniel D. HuSara L. ColeChoon KimJed F. FisherMatthew M. ChampionShahriar Mobashery

microbiologyperiplasmic hub proteinbiochemistrymolecular biologyenzymesprotein science

Restoring Susceptibility to β-Lactam Antibiotics in Methicillin-Resistant Staphylococcus Aureus. Nature Chemical Biology (2024)

Van T. NguyenBiruk T. BirhanuVega Miguel-RuanoChoon KimMayte BatuecasJingdong YangAmr M. El-ArabyEva Jiménez-FaracoValerie A. SchroederAlejandra AlbaNeha RanaSafaa SaderCaitlyn A. ThomasRhona FeltzerMijoon LeeJed F. FisherJuan A. HermosoMayland ChangShahriar Mobashery

pathogenic bacteriainfection controldrug resistanceantimicrobial resistanceantimicrobial susceptibilityclinical microbiologyantibioticsantimicrobial agentsb-lactam antibioticsmicrobiologyantibiotic resistanceantimicrobial stewardshipklebsiella pneumoniaeinfectious diseasesantimicrobial resistance geneschemical biologyhospital infectionsapplied microbiologypublic healthmethicillin-resistant staphylococcus aureus

Structural Characterization of Lytic Transglycosylase Mltd of Pseudomonas Aeruginosa, a Target for the Natural Product Bulgecin A. International Journal of Biological Macromolecules (2024)

Vega Miguel-RuanoRhona FeltzerMaría T. BatuecasBalajee RamachandranAmr M. El-ArabyLuis F. Avila-CobianStefania De BenedettiShahriar MobasheryJuan A. Hermoso

microbial physiologymicrobiologybiomolecular structurenatural product bulgecinstructural biologystructural characterizationpseudomonas aeruginosaprotein structuremicrobial geneticsbiochemistrymolecular biologystructural molecular biologylytic transglycosylase mltdbiological macromoleculesenzymesprotein science

A Dual-Action Antibiotic That Kills Clostridioides Difficile Vegetative Cells and Inhibits Spore Germination. Proceedings of the National Academy of Sciences (2023)

Jeshina JanardhananChoon KimYuanyuan QianJingdong YangJayda E. MeiselDerong DingEnrico SperiValerie A. SchroederWilliam R. WolterAllen G. OliverShahriar MobasheryMayland Chang

pharmacologyinfection controlepidemiologyclinical microbiologyapplied microbiologytreatment and preventionbacteriaveterinary medicinepublic healthhost-guest chemistryantibiotics

Amber‐Codon Suppression for Spatial Localization and in Vivo Photoaffinity Capture of the Interactome of the Pseudomonas Aeruginosa Rare Lipoprotein a Lytic Transglycosylase. Protein Science (2023)

Luis F. Avila‐CobianHidekazu HoshinoMark E. HorsmanVan T. NguyenYuanyuan QianRhona FeltzerChoon KimDaniel D. HuMatthew M. ChampionJed F. FisherShahriar Mobashery

liver physiologyhost specificityspatial localizationbiochemistrybiomolecular interactionsprotein sciencemembrane biologyproteomicsmolecular microbiologymolecular physiologypharmacologystructural biologyprotein structureredox biologyamber-codon suppressionenzymesprotein chemistrymicrobial physiologyenzyme inhibitionmolecular biologylytic transglycosylase

A Potent and Narrow-Spectrum Antibacterial Against Clostridioides Difficile Infection. Journal of Medicinal Chemistry (2023)

Yuanyuan QianBiruk T. BirhanuJingdong YangDerong DingJeshina JanardhananShahriar MobasheryMayland Chang

medicinal chemistrypharmacologyinfection controlmedicineinfectious diseasesantibacterial agentsnarrow-spectrum antibacterialveterinary medicineclinical microbiology

Application of 2D-Itc to the Elucidation of the Enzymatic Mechanism of N -Acetylmuramic Acid/ N -Acetylglucosamine Kinase (Amgk) From Pseudomonas Aeruginosa. Biochemistry (2023)

Amr M. El-ArabyRhona FeltzerChoon KimShahriar Mobashery

geneticspharmacologymedicinal chemistrygene expressiondrug discoveryprotein engineeringbiological chemistryenzyme catalysisenzymatic modificationenzyme inhibitionbiochemistryredox biologyenzymatic mechanismprotein synthesisenzymesprotein scienceprotein chemistry

Catalytic Process of Anhydro-N-Acetylmuramic Acid Kinase From Pseudomonas Aeruginosa. Journal of Biological Chemistry (2023)

Amr M. El-ArabyEva Jiménez-FaracoRhona FeltzerJose M. Martin-GarciaBhaskara Rao KarriBalajee RamachandranChoon KimJed F. FisherJuan A. HermosoShahriar Mobashery

anhydro-n-acetylmuramic acid kinasemicrobiologybiological chemistryenzyme catalysisbiocatalysisapplied microbiologypseudomonas aeruginosabiochemistrymolecular biologycatalysisbiotechnologymolecular catalysisenzymesprotein chemistry

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Shahriar Mobashery

University of Notre Dame

Affiliations

College of Science

Chemistry and Biochemistry

NoneShahriar Mobashery is currently serving as a Chemistry And Biochemistry faculty at University of Notre Dame.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Shahriar Mobashery

University of Notre Dame

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bacterial Peptidoglycan as a Living Polymer. Current Opinion in Chemical Biology (2024)

Amr M El-ArabyJed F FisherShahriar Mobashery

bacterial peptidoglycanliving polymerbiochemistrychemical biologybiopolymers

Characterization of Vlde (Spr1875), a Pneumococcal Two-State L, D -Endopeptidase With a Four-Zinc Cluster in the Active Site. ACS Catalysis (2024)

Lytic Transglycosylase Slt of Pseudomonas Aeruginosa as a Periplasmic Hub Protein. Protein Science (2024)

Luis F. Avila‐CobianStefania De BenedettiHidekazu HoshinoVan T. NguyenAmr M. El‐ArabySafaa SaderDaniel D. HuSara L. ColeChoon KimJed F. FisherMatthew M. ChampionShahriar Mobashery

microbiologyperiplasmic hub proteinbiochemistrymolecular biologyenzymesprotein science

Restoring Susceptibility to β-Lactam Antibiotics in Methicillin-Resistant Staphylococcus Aureus. Nature Chemical Biology (2024)

Structural Characterization of Lytic Transglycosylase Mltd of Pseudomonas Aeruginosa, a Target for the Natural Product Bulgecin A. International Journal of Biological Macromolecules (2024)

Vega Miguel-RuanoRhona FeltzerMaría T. BatuecasBalajee RamachandranAmr M. El-ArabyLuis F. Avila-CobianStefania De BenedettiShahriar MobasheryJuan A. Hermoso

A Dual-Action Antibiotic That Kills Clostridioides Difficile Vegetative Cells and Inhibits Spore Germination. Proceedings of the National Academy of Sciences (2023)

Jeshina JanardhananChoon KimYuanyuan QianJingdong YangJayda E. MeiselDerong DingEnrico SperiValerie A. SchroederWilliam R. WolterAllen G. OliverShahriar MobasheryMayland Chang

pharmacologyinfection controlepidemiologyclinical microbiologyapplied microbiologytreatment and preventionbacteriaveterinary medicinepublic healthhost-guest chemistryantibiotics

Luis F. Avila‐CobianHidekazu HoshinoMark E. HorsmanVan T. NguyenYuanyuan QianRhona FeltzerChoon KimDaniel D. HuMatthew M. ChampionJed F. FisherShahriar Mobashery

A Potent and Narrow-Spectrum Antibacterial Against Clostridioides Difficile Infection. Journal of Medicinal Chemistry (2023)

Yuanyuan QianBiruk T. BirhanuJingdong YangDerong DingJeshina JanardhananShahriar MobasheryMayland Chang

medicinal chemistrypharmacologyinfection controlmedicineinfectious diseasesantibacterial agentsnarrow-spectrum antibacterialveterinary medicineclinical microbiology

Application of 2D-Itc to the Elucidation of the Enzymatic Mechanism of N -Acetylmuramic Acid/ N -Acetylglucosamine Kinase (Amgk) From Pseudomonas Aeruginosa. Biochemistry (2023)

Amr M. El-ArabyRhona FeltzerChoon KimShahriar Mobashery

Catalytic Process of Anhydro-N-Acetylmuramic Acid Kinase From Pseudomonas Aeruginosa. Journal of Biological Chemistry (2023)

Amr M. El-ArabyEva Jiménez-FaracoRhona FeltzerJose M. Martin-GarciaBhaskara Rao KarriBalajee RamachandranChoon KimJed F. FisherJuan A. HermosoShahriar Mobashery

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