Faculty

Institution

Unit

Venue

Yusuke Okuno

Assistant Professor of Chemistry

Washington University in St. Louis

Affiliations

Arts & Sciences

Chemistry

Yusuke Okuno is currently serving as an Arts & Sciences Assistant Professor of Chemistry at Washington University In St. Louis.

Honors

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Experiences

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Education

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Yusuke Okuno

Washington University in St. Louis

Assistant Professor of Chemistry

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biophysics protein science nuclear magnetic resonance molecular biology magnetic resonance structural biology biochemistry physical chemistry biophysical chemistry protein chemistry neuroscience protein structure structural molecular biology dynamic nuclear polarization single molecule biophysics quantitative interpretation gene expression dna repair membrane biology molecular science molecular liquids single-molecule detection electron paramagnetic resonance spin phenomenon relaxation process spin dynamics protein-cosolute interactions nucleic acids molecular physiology biomedical imaging biological macromolecules nanoparticle research transition metal chemistry membrane science electroanalytical chemistry interface science quantum chemistry photomedicine rna biology oligonucleotides molecular neurobiology molecular regulation host-guest chemistry emulation technique molecular recognition human sciences biomolecular analysis transcriptomics technology molecular characterization electron spectroscopy interfacial studies molecule-based magnet novel interface protein nmr nuclear magnetic resonance spectroscopy diffusion process experimental biophysics electrochemical interfaces molecular electrochemistry molecular kinetics magnetic resonance spectroscopy chemical probes solution nmr sensitivity enhancement dna binding tyrosine phosphorylation dnak molecular chaperone heterogeneous binding photo-cidnp sensitizer low micromolar concentration basic principles mismatch repair d-loop recombination intermediate solvent paramagnetic relaxation submicromolar concentration kinetic trapping biomolecular structure solution-state nmr protein hydration

Notable Scholarly Works

Notable Federal Grants

Collaborators

Quantitative Interpretation of Transverse Spin Relaxation by Translational Diffusion in Liquids. The Journal of Physical Chemistry B (2025)

physicsbiophysicsrelaxation processmagnetic resonancediffusion processspin phenomenonfluid dynamicsspin dynamicsquantitative interpretationtranslational diffusioncondensed matter physicsdiffusiontransverse spin relaxationmolecular liquidscomplex fluids

Solvent Pre and Effective Near Surface Electrostatics: Theory, Methods, and Biological Insights. (2025)

biophysicsmolecular electrochemistryinterface sciencesurface scienceinterface (matter)solvent premolecular liquidselectroanalytical chemistrychemistrybiological insightselectrochemical interfaces

Quantitative Interpretation of Transverse Spin Relaxation by Translational Diffusion in Liquids Under Arbitrary Potentials. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Yusuke Okuno

arbitrary potentialsbiophysicsquantitative interpretationtranslational diffusioncondensed matter physicsdiffusiontransverse spin relaxation

Theory and Applications of Nitroxide-Based Paramagnetic Cosolutes for Probing Intermolecular and Electrostatic Interactions on Protein Surfaces. Journal of the American Chemical Society (2022)

Yusuke OkunoCharles D. SchwietersZhilin YangG. Marius Clore

protein structuremolecule-based magnetelectrostatic interactionsmembrane scienceprotein surfacesbiochemistrybiophysical chemistrysingle molecule biophysicschemical biologyinterfacial studiesstructural biologyprotein scienceprotein chemistrynitroxide-based paramagnetic cosolutestransition metal chemistrybiophysicssurface sciencenanoparticle researchmolecular biologystructural molecular biologynovel interface

Atomic View of Cosolute-Induced Protein Denaturation Probed by Nmr Solvent Paramagnetic Relaxation Enhancement. Proceedings of the National Academy of Sciences (2021)

Yusuke OkunoJanghyun YooCharles D. SchwietersRobert B. BestHoi Sung ChungG. Marius Clore

biophysical chemistrybiophysicsmolecular biophysicsmagnetic resonanceprotein chemistryprotein structureprotein nmrnuclear magnetic resonance spectroscopymolecular biologystructural molecular biologynuclear magnetic resonanceprotein scienceprotein foldingcosolute-induced protein denaturationbiochemistry

Quantitative Interpretation of Solvent Paramagnetic Relaxation for Probing Protein–Cosolute Interactions. Journal of the American Chemical Society (2020)

Yusuke OkunoAttila SzaboG. Marius Clore

biophysical chemistrybiophysicsmolecular biophysicsmagnetic resonanceprotein chemistrysingle molecule biophysicsquantitative interpretationprotein structuremolecular modellingchemical biologyprotein-cosolute interactionsmolecular biologystructural molecular biologysolvent paramagnetic relaxationprotein sciencebiochemistry

Submillisecond Freezing Permits Cryoprotectant‐Free Epr Double Electron−Electron Resonance Spectroscopy. ChemPhysChem (2020)

Thomas SchmidtJaekyun JeonYusuke OkunoSai C. ChiliveriG. Marius Clore

physical chemistryspectroscopyelectron paramagnetic resonancechemistryelectron spectroscopy

Laser- and Cryogenic Probe-Assisted Nmr Enables Hypersensitive Analysis of Biomolecules at Submicromolar Concentration. Proceedings of the National Academy of Sciences (2019)

Yusuke OkunoMiranda F. MechaHanming YangLingchao ZhuCharles G. FrySilvia Cavagnero

biological macromoleculessubmicromolar concentrationhuman sciencessingle-molecule detectionmolecular sciencestructural biologyprotein sciencenanotechnologymembrane biologymolecular characterizationbiomedical imagingnuclear magnetic resonancemolecular physiologybiomolecular analysistranscriptomics technologybiophysicsbiomedical engineeringbiomolecular engineeringbiological imaging

Kinetic Trapping of Folded Proteins Relative to Aggregates Under Physiologically Relevant Conditions. The Journal of Physical Chemistry B (2018)

Angela E. VarelaJonathan F. LangYufan WuMatthew D. DalphinAndrew J. StanglYusuke OkunoSilvia Cavagnero

physiologybiophysicsphysical chemistryfolded proteinsstructural biologyprotein sciencekinetic trappingprotein folding

Laser-Assisted Nmr in the Presence of a Cryogenic Probe Enables Multidimensional Data Collection on Amino Acids and Proteins at Unprecedented Sensitivity. Biophysical Journal (2018)

Miranda MechaYusuke OkunoHanming YangSilvia Cavagnero

biophysical chemistrybiophysicsproteomicsmolecular biophysicscryogenic probeexperimental biophysicslaser-assisted nmrbiomolecular engineeringmolecular biologymultidimensional data collectionstructural biologynuclear magnetic resonanceprotein scienceamino acids

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Yusuke Okuno

Assistant Professor of Chemistry

Washington University in St. Louis

Affiliations

Arts & Sciences

Chemistry

Yusuke Okuno is currently serving as an Arts & Sciences Assistant Professor of Chemistry at Washington University In St. Louis.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Yusuke Okuno

Washington University in St. Louis

Assistant Professor of Chemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Quantitative Interpretation of Transverse Spin Relaxation by Translational Diffusion in Liquids. The Journal of Physical Chemistry B (2025)

Solvent Pre and Effective Near Surface Electrostatics: Theory, Methods, and Biological Insights. (2025)

biophysicsmolecular electrochemistryinterface sciencesurface scienceinterface (matter)solvent premolecular liquidselectroanalytical chemistrychemistrybiological insightselectrochemical interfaces

Quantitative Interpretation of Transverse Spin Relaxation by Translational Diffusion in Liquids Under Arbitrary Potentials. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Yusuke Okuno

arbitrary potentialsbiophysicsquantitative interpretationtranslational diffusioncondensed matter physicsdiffusiontransverse spin relaxation

Theory and Applications of Nitroxide-Based Paramagnetic Cosolutes for Probing Intermolecular and Electrostatic Interactions on Protein Surfaces. Journal of the American Chemical Society (2022)

Yusuke OkunoCharles D. SchwietersZhilin YangG. Marius Clore

Atomic View of Cosolute-Induced Protein Denaturation Probed by Nmr Solvent Paramagnetic Relaxation Enhancement. Proceedings of the National Academy of Sciences (2021)

Yusuke OkunoJanghyun YooCharles D. SchwietersRobert B. BestHoi Sung ChungG. Marius Clore

Quantitative Interpretation of Solvent Paramagnetic Relaxation for Probing Protein–Cosolute Interactions. Journal of the American Chemical Society (2020)

Yusuke OkunoAttila SzaboG. Marius Clore

Submillisecond Freezing Permits Cryoprotectant‐Free Epr Double Electron−Electron Resonance Spectroscopy. ChemPhysChem (2020)

Thomas SchmidtJaekyun JeonYusuke OkunoSai C. ChiliveriG. Marius Clore

physical chemistryspectroscopyelectron paramagnetic resonancechemistryelectron spectroscopy

Laser- and Cryogenic Probe-Assisted Nmr Enables Hypersensitive Analysis of Biomolecules at Submicromolar Concentration. Proceedings of the National Academy of Sciences (2019)

Yusuke OkunoMiranda F. MechaHanming YangLingchao ZhuCharles G. FrySilvia Cavagnero

Kinetic Trapping of Folded Proteins Relative to Aggregates Under Physiologically Relevant Conditions. The Journal of Physical Chemistry B (2018)

Angela E. VarelaJonathan F. LangYufan WuMatthew D. DalphinAndrew J. StanglYusuke OkunoSilvia Cavagnero

physiologybiophysicsphysical chemistryfolded proteinsstructural biologyprotein sciencekinetic trappingprotein folding

Laser-Assisted Nmr in the Presence of a Cryogenic Probe Enables Multidimensional Data Collection on Amino Acids and Proteins at Unprecedented Sensitivity. Biophysical Journal (2018)

Miranda MechaYusuke OkunoHanming YangSilvia Cavagnero

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3
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Iowa State University

biomolecular structure

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biomolecular structure

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