Faculty

Institution

Unit

Venue

Anne-Frances Miller

Professor of Chemistry and of Biochemistry

University of Kentucky

Affiliations

College of Arts & Sciences

Chemistry

Anne-frances Miller is currently serving as a Chemistry Professor of Chemistry and of Biochemistry at University of Kentucky.

Honors

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Experiences

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Education

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Anne-Frances Miller

University of Kentucky

Professor of Chemistry and of Biochemistry

You can click a keyword to filter the displayed items

biochemistry biophysics molecular biology enzymes protein science redox biology structural biology chemistry chemical biology biological chemistry transition metal chemistry free radical biology oxidative stress structural molecular biology biological inorganic chemistry inorganic chemistry nuclear magnetic resonance biophysical chemistry membrane biology protein chemistry redox chemistry enzyme inhibition protein nmr reactive oxygen species biomolecular structure chemical sciences structural chemistry nuclear magnetic resonance spectroscopy bioelectrochemistry coordination chemistry molecular structure biochemical sciences redox signaling enzyme catalysis electron bifurcation quantum chemistry catalyst activation enzyme specificity electronic structure microbial physiology solid-state nmr spectroscopy biomolecular interactions fe-superoxide dismutase superoxide dismutase atomic spectroscopy magnetic resonance magnetic resonance spectroscopy biocatalysis superoxide dismutases two-electron reduction quantitative structure-activity relationships solid-state nmr electron transfer flavoproteins inhibitory activity reactive nitrogen species structure-function enzyme kinetics hydrogen bond spectroscopic methods surface reactivity spectra-structure correlation protein purification mutagenesis biomolecular analysis protein evolution flavin-based electron bifurcation manganese superoxide dismutase mn-superoxide dismutase nitroaromatic compounds computational studies second-sphere contributions functional modification selective toxicity molecular basis cellular enzymology superoxide reductases ancient enzymes

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 4374 How Redox Tuning by the Protein Enables Life to Use Flavins to Circumvent Iron Scarcity or Toxicity, as Exemplified by an All-Flavin Electron Bifurcating Enzyme. Journal of Biological Chemistry (2026)

redox biologyredox chemistryenzymesmolecular biologybiological chemistrybiochemistry

Cyclometalated Gold(III)‐Mediated Cysteine Arylation: A Bioorthogonal Platform for Covalent Targeting of Intrinsically Disordered Proteins. Angewandte Chemie International Edition (2025)

future medicinal chemistrychemical biologychemistrybiochemistrybio-orthogonal chemistry

Electrochemical Observation and Ph Dependence of All Three Expected Redox Couples in an Extremophilic Bifurcating Electron Transfer Flavoprotein With Fused Subunits. JACS Au (2025)

electrochemistryredox chemistrybiochemistryredox biology

A Single Hydrogen Bond That Tunes Flavin Redox Reactivity and Activates It for Modification. Chemical Science (2024)

Debarati DasAnne-Frances Miller

flavin redox reactivitychemical scienceschemistrysingle hydrogen bondhydrogen bond

Extended Conformations of Bifurcating Electron Transfer Flavoprotein Constitute Up to Half the Population, Possibly Mediating Conformational Change. Chemical Science (2024)

Sharique A. KhanAlan HicksWellington C. LeiteJames ByrnesBiswajit GoraiMaria-Andrea MroginskiHugh O'NeillAnne-Frances Miller

electron transfer flavoproteinprotein structureconformational studiesmolecular biologychemical sciencesconformational changebiochemistry

Sedimentation of Large, Soluble Proteins Up to 140 Kda for 1H-Detected Mas Nmr and 13C Dnp Nmr – Practical Aspects. Journal of Biomolecular NMR (2024)

Dallas BellFlorian LindemannLisa GerlandHanna AucharovaAlexander KleinDaniel FriedrichMatthias HillerKristof GroheTobias MeierBarth van RossumAnne DiehlJon HughesLeonard J. MuellerRasmus LinserAnne-Frances MillerHartmut Oschkinat

biological macromoleculesprotein structureprotein nmrmass spectrometrybiochemistrypractical aspectsprotein purificationbiomolecular structureprotein scienceprotein mass spectrometrymembrane biologynuclear magnetic resonance spectroscopymembrane proteinsnuclear magnetic resonancebiomolecular analysisbiophysicsmolecular structurebiomolecular engineeringstructural molecular biology

Structure, Dynamics, and Redox Reactivity of an All-Purpose Flavodoxin. Journal of Biological Chemistry (2024)

Sharique KhanAhmadullah AnsariMonica BrachiDebarati DasWassim El HousseiniShelley MinteerAnne-Frances Miller

all-purpose flavodoxinredox chemistrymolecular biologybiological chemistrystructural biologyredox reactivitybiochemistry

19F Nmr Reveals Dynamics Not Evident in Crystal Structure of Long-Chain Flavodoxin. Biophysical Journal (2023)

Sharique KhanAnne-Frances MillerAhmadullah Ansari

biophysical chemistrybiophysicslong-chain flavodoxinprotein structureprotein nmrnuclear magnetic resonance

Abstract 1566: Role of Histidine290 in Tuning the Redox Activity of Electron Transfer-Fad in Electron Transfer Flavoprotein of Acidaminococcus Fermentans. Journal of Biological Chemistry (2023)

Debarati DasAnne-Frances Miller

medicinal chemistrymolecular biophysicspharmacologyenzyme inhibitionmicrobial physiologyelectron transfer flavoproteinredox biologychemical biologyenzymesmolecular biologybiological chemistryredox activityelectron transfer-fadbioelectrochemistrybiochemical sciencesmembrane biologyacidaminococcus fermentansbiochemistry

Abstract 1942: Interactions That Shape the Complementary Reactivities of Flavins in Bifurcating Electron Transferring Flavoproteins. Journal of Biological Chemistry (2023)

Anne-Frances MillerNishya Mohamed RaseekMaría Gozález-ViegasDebarati DasMaria-Andrea Mroginski

biophysicscomplementary reactivitiesproteinlipid interactionelectron transferring flavoproteinschemical biologymolecular biologybiological chemistryprotein sciencebiochemistry

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Anne-Frances Miller

Professor of Chemistry and of Biochemistry

University of Kentucky

Affiliations

College of Arts & Sciences

Chemistry

Anne-frances Miller is currently serving as a Chemistry Professor of Chemistry and of Biochemistry at University of Kentucky.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Anne-Frances Miller

University of Kentucky

Professor of Chemistry and of Biochemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

redox biologyredox chemistryenzymesmolecular biologybiological chemistrybiochemistry

Cyclometalated Gold(III)‐Mediated Cysteine Arylation: A Bioorthogonal Platform for Covalent Targeting of Intrinsically Disordered Proteins. Angewandte Chemie International Edition (2025)

future medicinal chemistrychemical biologychemistrybiochemistrybio-orthogonal chemistry

Electrochemical Observation and Ph Dependence of All Three Expected Redox Couples in an Extremophilic Bifurcating Electron Transfer Flavoprotein With Fused Subunits. JACS Au (2025)

electrochemistryredox chemistrybiochemistryredox biology

A Single Hydrogen Bond That Tunes Flavin Redox Reactivity and Activates It for Modification. Chemical Science (2024)

Debarati DasAnne-Frances Miller

flavin redox reactivitychemical scienceschemistrysingle hydrogen bondhydrogen bond

Extended Conformations of Bifurcating Electron Transfer Flavoprotein Constitute Up to Half the Population, Possibly Mediating Conformational Change. Chemical Science (2024)

Sharique A. KhanAlan HicksWellington C. LeiteJames ByrnesBiswajit GoraiMaria-Andrea MroginskiHugh O'NeillAnne-Frances Miller

electron transfer flavoproteinprotein structureconformational studiesmolecular biologychemical sciencesconformational changebiochemistry

Sedimentation of Large, Soluble Proteins Up to 140 Kda for 1H-Detected Mas Nmr and 13C Dnp Nmr – Practical Aspects. Journal of Biomolecular NMR (2024)

Structure, Dynamics, and Redox Reactivity of an All-Purpose Flavodoxin. Journal of Biological Chemistry (2024)

Sharique KhanAhmadullah AnsariMonica BrachiDebarati DasWassim El HousseiniShelley MinteerAnne-Frances Miller

all-purpose flavodoxinredox chemistrymolecular biologybiological chemistrystructural biologyredox reactivitybiochemistry

19F Nmr Reveals Dynamics Not Evident in Crystal Structure of Long-Chain Flavodoxin. Biophysical Journal (2023)

Sharique KhanAnne-Frances MillerAhmadullah Ansari

biophysical chemistrybiophysicslong-chain flavodoxinprotein structureprotein nmrnuclear magnetic resonance

Abstract 1566: Role of Histidine290 in Tuning the Redox Activity of Electron Transfer-Fad in Electron Transfer Flavoprotein of Acidaminococcus Fermentans. Journal of Biological Chemistry (2023)

Debarati DasAnne-Frances Miller

Abstract 1942: Interactions That Shape the Complementary Reactivities of Flavins in Bifurcating Electron Transferring Flavoproteins. Journal of Biological Chemistry (2023)

Anne-Frances MillerNishya Mohamed RaseekMaría Gozález-ViegasDebarati DasMaria-Andrea Mroginski

biophysicscomplementary reactivitiesproteinlipid interactionelectron transferring flavoproteinschemical biologymolecular biologybiological chemistryprotein sciencebiochemistry

1
2
3
4
5
11
10 / page

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Similar Faculty Members

Rajeev Prabhakar

Institution

University of Miami

biochemistry

enzymes

Kyle M. Lancaster

Institution

Cornell University

small-molecule activation

coordination chemistry

Leonard Mueller

Institution

University of California, Riverside

physical chemistry

protein structure

Thomas Pochapsky

Institution

Brandeis University

biomolecular structure

protein structure

James Cowan

Institution

Ohio State University

metallodrug discovery

transition metal chemistry

John Enemark

Institution

University of Arizona

biomolecular engineering

enzyme

Yisong Alex Guo

Institution

Carnegie Mellon University

structural chemistry

particle physics

Carsten Krebs

Institution

Pennsylvania State University

enzyme catalysis

energy research

Randy Larsen

Institution

University of South Florida

biomimetic chemistry

biomolecular engineering

Martin L. Kirk

Institution

University of New Mexico

chemical biology

general chemistry