Faculty

Institution

Unit

Venue

Jiyong Hong

Professor Associate Professor

Duke University

Affiliations

Trinity College of Arts & Sciences

Chemistry

Duke University School of Medicine

Molecular Cancer Biology

Pharmacology

Jiyong Hong is currently serving as a Chemistry Professor Associate Professor at Duke University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jiyong Hong

Duke University

Professor Associate Professor

You can click a keyword to filter the displayed items

pharmacology chemistry organic synthesis medicinal chemistry drug discovery organic chemistry medicine enzyme inhibition chemical synthesis immunology medicinal research stereoselective synthesis oncology pharmaceutical chemistry cancer biology tumor biology synthetic biology total synthesis protein science natural product synthesis natural product research synthetic chemistry clinical chemistry pharmacotherapy structural chemistry transition metal chemistry nucleic acids functional modification pharmaceutical sciences biological evaluation absolute configuration applied microbiology molecular cancer drug targeting drug development cancer treatment lead identification cancer cells structural molecular biology cancer care bone research mammalian biology heterocyclic in vivo systems immunosuppression clinical pharmacology antibiotic resistance antimicrobial chemotherapy largazole analogues structural basis formal synthesis stereoselective formal synthesis synthetic efforts mitochondrial function metabolic remodeling cancer immunosurveillance immunoediting microbial physiology lipid analysis proteinlipid interaction lipid peroxidation lipoprotein metabolism experimental pharmacology host specificity cancer genomics cancer management cancer genetics x-ray fluorescence cd8 t cells cd8 til histone deacetylase inhibitor molecular target mutagenic translesion synthesis broad-spectrum therapy natural product diversity oxidative macrolactonization

Notable Scholarly Works

Notable Federal Grants

Collaborators

Identification of 4,5,6,7-Tetrabromo-1 H -Benzotriazole (Tbb) as a Small Molecule Mesh1 Inhibitor That Suppresses Ferroptosis. bioRxiv (Cold Spring Harbor Laboratory) (2026)

enzyme inhibitionbiochemistrymechanisms of actionsmall molecules

Mesh1-Mediated Coenzyme a Degradation Drives Ferroptosis Sensitivity and Muscle Pathology. Journal of Clinical Investigation (2026)

musculoskeletal disordersmuscular dystrophiesbiochemistryskeletal muscle

Subunit Selective Modulation of Gaba a Receptors Using Pharmacogenetically Tethered Neurosteroids. bioRxiv (Cold Spring Harbor Laboratory) (2026)

receptorsneuropharmacologyneuronsneuroscienceneurotransmitterspharmacologyneuropsychopharmacology

Abstract 4343799: Genetically Informed Drug Targeting of Ryanodine Receptor Type 2 Identifies New Precision Therapeutic Candidates for Catecholaminergic Polymorphic Ventricular Tachycardia. Circulation (2025)

cardiomyopathyreceptorscirculatory physiologycardiologycardiovascular physiologymechanisms of actionelectrophysiologypharmacologyphysiologymolecular pharmacologycardiovascular pharmacologypharmacotherapycardiovascular researchmolecular physiologycardiac muscle

Asymmetric Synthesis of the Trpv1 Modulator Amg8562 via Lipase-Catalyzed Kinetic Resolution. ACS Omega (2025)

chemical biologybiochemistryenzyme catalysisbiochemical sciences

Asymmetric Total Synthesis of 4,9,10-Trihydroxyguaia-11(13)En-12,6-Olide and Discovery of Its Anticancer Activity Against Atypical Teratoid Rhabdoid Tumor. ACS Central Science (2025)

chemical synthesisorganic synthesispharmacologynatural product researchdrug discoverynatural product synthesis

Asymmetric Total Synthesis of Daucane-Type Sesquiterpenoids (+)-Ferutinin and (+)-Kuhistanicaol G. Organic Letters (2025)

organic chemistrychemical synthesisnatural productsbioactive compoundsmedicinal chemistryphytochemical analysissynthetic chemistryorganic synthesispharmacologynatural product biosynthesisnatural product researchnatural product synthesis

Author Response for"Rev1 Inhibition Enhances Trinucleotide Repeat Mutagenesis". (2025)

mutagenesis (molecular biology technique)geneticsnucleic acidsgenome instabilitymutagenesisdna repairmolecular biology

From Obscurity to Opportunity: Lpxh Emerges as a Promising Antibiotic Target in the Battle Against Gram-Negative Pathogens. ACS Infectious Diseases (2025)

pathogenic bacteriamicrobiologyantibiotic resistanceantimicrobial agentsinfectious diseasesantimicrobial chemotherapyantimicrobial susceptibilityclinical microbiologyantibioticsantimicrobial resistance

Mechanisms of Rev1-Dependent Trinucleotide Repeat Instability (P12-5.029). Neurology (2025)

neurodegenerative diseasesgenome instabilityneurogeneticsmolecular neurodegenerationdna repairneurology

1
2
3
4
5
11
10 / page

Jiyong Hong

Professor Associate Professor

Duke University

Affiliations

Trinity College of Arts & Sciences

Chemistry

Duke University School of Medicine

Molecular Cancer Biology

Pharmacology

Jiyong Hong is currently serving as a Chemistry Professor Associate Professor at Duke University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jiyong Hong

Duke University

Professor Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Identification of 4,5,6,7-Tetrabromo-1 H -Benzotriazole (Tbb) as a Small Molecule Mesh1 Inhibitor That Suppresses Ferroptosis. bioRxiv (Cold Spring Harbor Laboratory) (2026)

enzyme inhibitionbiochemistrymechanisms of actionsmall molecules

Mesh1-Mediated Coenzyme a Degradation Drives Ferroptosis Sensitivity and Muscle Pathology. Journal of Clinical Investigation (2026)

musculoskeletal disordersmuscular dystrophiesbiochemistryskeletal muscle

Subunit Selective Modulation of Gaba a Receptors Using Pharmacogenetically Tethered Neurosteroids. bioRxiv (Cold Spring Harbor Laboratory) (2026)

receptorsneuropharmacologyneuronsneuroscienceneurotransmitterspharmacologyneuropsychopharmacology

Asymmetric Synthesis of the Trpv1 Modulator Amg8562 via Lipase-Catalyzed Kinetic Resolution. ACS Omega (2025)

chemical biologybiochemistryenzyme catalysisbiochemical sciences

Asymmetric Total Synthesis of 4,9,10-Trihydroxyguaia-11(13)En-12,6-Olide and Discovery of Its Anticancer Activity Against Atypical Teratoid Rhabdoid Tumor. ACS Central Science (2025)

chemical synthesisorganic synthesispharmacologynatural product researchdrug discoverynatural product synthesis

Asymmetric Total Synthesis of Daucane-Type Sesquiterpenoids (+)-Ferutinin and (+)-Kuhistanicaol G. Organic Letters (2025)

Author Response for"Rev1 Inhibition Enhances Trinucleotide Repeat Mutagenesis". (2025)

mutagenesis (molecular biology technique)geneticsnucleic acidsgenome instabilitymutagenesisdna repairmolecular biology

From Obscurity to Opportunity: Lpxh Emerges as a Promising Antibiotic Target in the Battle Against Gram-Negative Pathogens. ACS Infectious Diseases (2025)

Mechanisms of Rev1-Dependent Trinucleotide Repeat Instability (P12-5.029). Neurology (2025)

neurodegenerative diseasesgenome instabilityneurogeneticsmolecular neurodegenerationdna repairneurology

1
2
3
4
5
11
10 / page

Similar Faculty Members

Jeffrey D. Winkler

Institution

University of Pennsylvania

organic synthesis

chemistry

Dennis Wright

Institution

University of Connecticut

future medicinal chemistry

complex natural products

Daniel Romo

Institution

Baylor University

organic synthesis

chemistry

Michael Jung

Institution

University of California, Los Angeles

organic chemistry

synthetic organic chemistry

Jetze Tepe

Institution

University of Virginia

pharmacology

organic synthesis

Umesh Desai

Institution

Virginia Commonwealth University

pathology

microbial infection

Richard B. Silverman

Institution

Northwestern University

pharmacology

medicinal chemistry

John Porco

Institution

Boston University

complex synthesis

complex chemical libraries

Charles E. McKenna

Institution

University of Southern California

future medicinal chemistry

medicinal chemistry

Hendrik Luesch

Institution

University of Florida

marine cyanobacteria

natural product biosynthesis

Similar Faculty Members

Jeffrey D. Winkler

Institution

University of Pennsylvania

organic synthesis

chemistry

Dennis Wright

Institution

University of Connecticut

future medicinal chemistry

complex natural products

Daniel Romo

Institution

Baylor University

organic synthesis

chemistry

Michael Jung

Institution

University of California, Los Angeles

organic chemistry

synthetic organic chemistry

Jetze Tepe

Institution

University of Virginia

pharmacology

organic synthesis

Umesh Desai

Institution

Virginia Commonwealth University

pathology

microbial infection

Richard B. Silverman

Institution

Northwestern University

pharmacology

medicinal chemistry

John Porco

Institution

Boston University

complex synthesis

complex chemical libraries

Charles E. McKenna

Institution

University of Southern California

future medicinal chemistry

medicinal chemistry

Hendrik Luesch

Institution

University of Florida

marine cyanobacteria

natural product biosynthesis