Faculty

Institution

Unit

Venue

Gregory DeKoster

Research Instructor

Washington University in St. Louis

Affiliations

School of Medicine

Department of Biochemistry and Molecular Biophysics

Gregory Dekoster is currently serving as a Biochemistry And Molecular Biophysics Research Instructor at Washington University In St. Louis.

Honors

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Experiences

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Education

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Gregory DeKoster

Washington University in St. Louis

Research Instructor

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biochemistry biophysics protein science pharmacology molecular biology structural biology nuclear magnetic resonance protein structure medicinal chemistry structural molecular biology conformational studies protein nmr microbial pathogenesis membrane biology biological chemistry liver physiology biomolecular structure protein chemistry protein synthesis nmr structure bile salts protein-ligand interactions nanotechnology machine learning redox biology clinical lipidology enzyme inhibition food chemistry structural chemistry clinical microbiology thrombosis biochemical sciences peptides drug development emerging infectious diseases host-parasite relationships biomolecular interactions in-situ conversion molecular substrates path dependence protein function molecular microbiology proteinlipid interaction functional modification gastrointestinal pharmacology carbohydrate-protein interactions virulence factors protein structure prediction nuclear magnetic resonance spectroscopy protein assembly protein x-ray crystallography biophysical modeling rna biology organometallic catalysis experimental biophysics gene regulation asymmetric structures plasmodium vivax structural basis dbp engagement single hydroxyl group site selectivity lipid-bound forms structural homology fungal virulence factor nmr probes small molecule effector ternary complex ligand binding molecular characterization molecular science molecular biophysics biophysical chemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

Apolipoprotein E4 Has Extensive Conformational Heterogeneity in Lipid-Free and Lipid-Bound Forms. Proceedings of the National Academy of Sciences (2023)

Melissa D. Stuchell-BreretonMaxwell I. ZimmermanJustin J. MillerUpasana L. MallimadugulaJ. Jeremías InciccoDebjit RoyLouis G. SmithJasmine CubukBerevan BabanGregory T. DeKosterCarl FriedenGregory R. BowmanAndrea Soranno

neurologyproteomicsconformational studiesprotein scienceepigeneticsneurosciencemembrane biologymolecular biologyprotein structurelipid-bound formsstructural biology

Single-Molecule Spectroscopy of Apolipoprotein E Reveals a Complex Conformational Ensemble. Biophysical Journal (2023)

Melissa D. Stuchell-BreretonMaxwell I. ZimmermanJustin J. MillerUpasana L. MallimadugulaJuan J. InciccoDebjit RoyLouis G. SmithJasmine CubukBerevan BabanGregory T. DeKosterCarl FriedenGregory R. BowmanAndrea Soranno

biophysicsconformational studiesprotein sciencecell biologymolecular biophysicsmolecular biologyprotein structuresingle-molecule spectroscopystructural biology

Single-Molecule Fluorescence Spectroscopy of Apolipoprotein E. Biophysical Journal (2022)

Melissa D. Stuchell-BreretonMaxwell I. ZimmermanUpasana L. MallimadugulaJ. Jeremias InciccoDebjit RoyBerevan BabanGregory T. DeKosterGregory BowmanCarl FriedenAndrea Soranno

biophysicsprotein sciencebiophysical chemistrybiochemistryfluorescence spectroscopymolecular biophysicsexperimental biophysicssingle-molecule fluorescence spectroscopymolecular biologyfluorescence

19 F Nmr Reveals the Conformational Properties of Free Thrombin and Its Zymogen Precursor Prethrombin-2. J Biol Chem (2020)

biophysicsstructural molecular biologyprotein sciencebiomolecular structurebiophysical chemistryprotein foldingbiochemistryf nmrzymogen precursor prethrombin-2protein nmrmolecular biologyprotein structurenuclear magnetic resonancestructural biologyfree thrombin

19F Nmr Reveals the Conformational Properties of Free Thrombin and Its Zymogen Precursor Prethrombin-2. Journal of Biological Chemistry (2020)

Eliza A. RubenPrafull S. GandhiZhiwei ChenSarah K. KoesterGregory T. DeKosterCarl FriedenEnrico Di Cera

molecular and cellular biologystructural molecular biologynuclear magnetic resonanceprotein x-ray crystallographyconformational studiesprotein nmrmolecular biologyprotein foldingprotein assemblythrombosisbiochemistrynuclear magnetic resonance spectroscopybiological chemistryprotein structurestructural biologybiophysicsnmr revealsprotein scienceconformational propertiesfree thrombin

Charge Reduction of Membrane Proteins in Native Mass Spectrometry Using Alkali Metal Acetate Salts. Analytical Chemistry (2020)

John T. PetroffAiling TongLawrence J. ChenGregory T. DekosterFarha KhanJeff AbramsonCarl FriedenWayland W. L. Cheng

biophysicsbiological engineeringcharge reductionanalytical chemistrymass spectrometrynative mass spectrometry

Controlling the Rate and Efficiency of Proton-Coupled Transport by Emre. Biophysical Journal (2020)

Nathan ThomasChao WuPeyton SpreackerGrant HusseySamantha WynneEva-Maria UhlemannChristopher TateGregory T. DeKosterKatherine Henzler-Wildman

biophysicsproton-coupled transportcondensed matter physicsphysiology

Molecular Principles Underlying Dual Rna Specificity in the Drosophila Snf Protein. Nature Communications (2018)

Gert WeberGregory T. DeKosterNicole HoltonKathleen B. HallMarkus C. Wahl

drosophila snf proteindual rna specificitymolecular principlesmolecular biologygene expressionrna biologygenetics

APOE: In Vitro Studies of a Small Molecule Effector. Biochemistry (2016)

Tridib MondalHanliu WangGregory T. DeKosterBerevan BabanMichael L. GrossCarl Frieden

small moleculessmall molecule effectorbiochemistry

Structural Determinants of Ligand Binding in the Ternary Complex of Human Ileal Bile Acid Binding Protein With Glycocholate and Glycochenodeoxycholate Obtained From Solution Nmr. FEBS Journal (2015)

Gergő HorváthÁkos BencsuraÁgnes SimonGregory P. TochtropGregory T. DeKosterDouglas F. CoveyDavid P. CistolaOrsolya Toke

lipidsliver physiologystructural determinantssolution nmrpharmacologyligand bindingstructural molecular biologyternary complexcarbohydrate-protein interactionsmolecular biophysicsgastrointestinal pharmacologymolecular biologybiomolecular structurebiochemistryglycobiologyprotein structurefunctional modificationstructural biologyprotein chemistryprotein scienceproteinlipid interactionstructural chemistry

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Gregory DeKoster

Research Instructor

Washington University in St. Louis

Affiliations

School of Medicine

Department of Biochemistry and Molecular Biophysics

Gregory Dekoster is currently serving as a Biochemistry And Molecular Biophysics Research Instructor at Washington University In St. Louis.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Gregory DeKoster

Washington University in St. Louis

Research Instructor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Apolipoprotein E4 Has Extensive Conformational Heterogeneity in Lipid-Free and Lipid-Bound Forms. Proceedings of the National Academy of Sciences (2023)

neurologyproteomicsconformational studiesprotein scienceepigeneticsneurosciencemembrane biologymolecular biologyprotein structurelipid-bound formsstructural biology

Single-Molecule Spectroscopy of Apolipoprotein E Reveals a Complex Conformational Ensemble. Biophysical Journal (2023)

biophysicsconformational studiesprotein sciencecell biologymolecular biophysicsmolecular biologyprotein structuresingle-molecule spectroscopystructural biology

Single-Molecule Fluorescence Spectroscopy of Apolipoprotein E. Biophysical Journal (2022)

Melissa D. Stuchell-BreretonMaxwell I. ZimmermanUpasana L. MallimadugulaJ. Jeremias InciccoDebjit RoyBerevan BabanGregory T. DeKosterGregory BowmanCarl FriedenAndrea Soranno

biophysicsprotein sciencebiophysical chemistrybiochemistryfluorescence spectroscopymolecular biophysicsexperimental biophysicssingle-molecule fluorescence spectroscopymolecular biologyfluorescence

19 F Nmr Reveals the Conformational Properties of Free Thrombin and Its Zymogen Precursor Prethrombin-2. J Biol Chem (2020)

19F Nmr Reveals the Conformational Properties of Free Thrombin and Its Zymogen Precursor Prethrombin-2. Journal of Biological Chemistry (2020)

Eliza A. RubenPrafull S. GandhiZhiwei ChenSarah K. KoesterGregory T. DeKosterCarl FriedenEnrico Di Cera

Charge Reduction of Membrane Proteins in Native Mass Spectrometry Using Alkali Metal Acetate Salts. Analytical Chemistry (2020)

John T. PetroffAiling TongLawrence J. ChenGregory T. DekosterFarha KhanJeff AbramsonCarl FriedenWayland W. L. Cheng

biophysicsbiological engineeringcharge reductionanalytical chemistrymass spectrometrynative mass spectrometry

Controlling the Rate and Efficiency of Proton-Coupled Transport by Emre. Biophysical Journal (2020)

Nathan ThomasChao WuPeyton SpreackerGrant HusseySamantha WynneEva-Maria UhlemannChristopher TateGregory T. DeKosterKatherine Henzler-Wildman

biophysicsproton-coupled transportcondensed matter physicsphysiology

Molecular Principles Underlying Dual Rna Specificity in the Drosophila Snf Protein. Nature Communications (2018)

Gert WeberGregory T. DeKosterNicole HoltonKathleen B. HallMarkus C. Wahl

drosophila snf proteindual rna specificitymolecular principlesmolecular biologygene expressionrna biologygenetics

APOE: In Vitro Studies of a Small Molecule Effector. Biochemistry (2016)

Tridib MondalHanliu WangGregory T. DeKosterBerevan BabanMichael L. GrossCarl Frieden

small moleculessmall molecule effectorbiochemistry

Gergő HorváthÁkos BencsuraÁgnes SimonGregory P. TochtropGregory T. DeKosterDouglas F. CoveyDavid P. CistolaOrsolya Toke

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Similar Faculty Members

Amjad Farooq

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molecular biology

human civilization

Paul Carey

Institution

Case Western Reserve University

biochemistry

molecular biology

David P. Weliky

Institution

Michigan State University

biomolecular structure

protein structure

Sharon Campbell

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University of North Carolina at Chapel Hill

pathology

carcinogenesis

Elisar J. Barbar

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Oregon State University

molecular biology

nuclear magnetic resonance spectroscopy

Thomas Pochapsky

Institution

Brandeis University

biomolecular structure

protein structure

Peter Z. Qin

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Peter G.W. Gettins

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University of Illinois Chicago

biochemistry

molecular biology

Michael Weiss

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molecular biology

structural biology

Ryan Mehl

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synthetic biology

biomolecular engineering