Faculty

Institution

Unit

Venue

Deborah Wuttke

Professor

University of Colorado Boulder

Affiliations

Natural Sciences

Biochemistry Department

College of Arts and Sciences

Natural Sciences

Deborah Wuttke is currently serving as a Biochemistry Professor at University of Colorado Boulder.

Honors

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Experiences

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Education

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Deborah Wuttke

University of Colorado Boulder

Professor

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molecular biology structural biology biochemistry genetics gene expression nucleic acids protein structure rna biology biophysics structural molecular biology protein science dna repair genomics transcription factors molecular cell biology gene recognition biomolecular structure genome biology bioinformatics enzymes gene function yeast biomolecular interactions molecular science peptides molecular structure structural bioinformatics protein structure prediction transcription regulation peptide science enzyme inhibition protein nmr pharmaceutical sciences structure elucidation protein function protein assembly molecular recognition rna processing solution structure biomolecules biological macromolecules bioenergetics transition metal chemistry virus research host specificity sequence analysis biological inorganic chemistry genome structure protein evolution virus-host interactions viral replication protein modeling protein genetics pharmaceutical research molecular docking molecular regulation molecular biological method electron transfer single-stranded dna dna-binding domain inhibitory activity molecular substrates molecular basis intermediate host ob-fold proteins nucleic acid recognition electron-tunneling pathways macromolecular structures maximum likelihood superpositioning tfiiia bound cognate dna sequence sequence specificity zinc fingers conserved structure ruthenium-modified proteins domain packing

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dna Affinity Driven Chromatin Dynamics Determine Estrogen Receptor α Transcriptional Activity Independent of Rna Binding. Research Square (2026)

chromatin remodelingchromatin dynamicsnucleic acidscell biologytranscription factorsgene regulationmolecular cell biologynuclear organizationtranscription (biology)molecular biologychromatintranscription regulationdna affinitygene expressionhormonal receptor

Mecp2 Mbd-Id Module: A Unified Dna/Rna Binding Interface Disrupted in Rett Syndrome. bioRxiv (Cold Spring Harbor Laboratory) (2026)

oncogenesgenetic disordersgenome instabilityrecombination dynamicnucleic acidscell biologygenome biologygenomic mechanismsmecp2 mbd-id modulerett syndromemolecular geneticsmolecular cell biologymolecular biologychromatindna repairgenetics

The Canonical Rpa Complex Interacts With Est3 to Regulate Yeast Telomerase Activity. Proceedings of the National Academy of Sciences (2025)

molecular and cellular biologynucleic acidscell biologytranscription factorsmolecular cell biologyyeastmolecular regulationmolecular biologychromatintranscription regulationyeast telomerase activitygene expressiondna repaircellular biochemistry

A Distinct Mechanism of Rna Recognition by the Transcription Factor Gata1. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Daniella A. UgayRobert T. BateyDeborah S. Wuttke

rna recognitionmolecular recognitiontranscription factorstranscription (biology)molecular biologygene recognitiongene expressionrna biology

Guardians of the Genome: How the Single-Stranded Dna-Binding Proteins Rpa and Cst Facilitate Telomere Replication. Biomolecules (2024)

Conner L. OlsonDeborah S. Wuttke

dna replicationmolecular biologybiomolecules

The Rna-Binding Domain of Hnrnp U Extends Beyond the Rgg/Rg Motifs. Biochemistry (2024)

Otto A. KletzienDeborah S. WuttkeRobert T. Batey

rna-binding domaingene expressionmolecular biologybiochemistry

The Rna-Binding Selectivity of the Rgg/Rg Motifs of Hnrnp U is Abolished by Elements Within the C-Terminal Intrinsically Disordered Region. Journal of Molecular Biology (2024)

Otto A KletzienDeborah S WuttkeRobert T Batey

biophysicsmolecular and cellular biologybiochemistrymolecular cell biologymolecular biologychromatinprotein structuregene expressionstructural molecular biologyrna biologystructural biologyrna-binding selectivitygene structure

Transcription Factors Erα and Sox2 Have Differing Multiphasic Dna- and Rna-Binding Mechanisms. RNA (2024)

Wayne O HemphillHalley R SteinerJackson R KominskyDeborah S WuttkeThomas R Cech

transcription factors eratranscription factorsrna binding mechanismsmolecular biologymultiphasic dna

Quantification of Transcriptome Changes to Investigate the Role of Glucocorticoid Receptor-Rna Binding During Dexamethasone Treatment. BMC Research Notes (2023)

Nickolaus C. LammerMary A. AllenRobert T. BateyDeborah S. Wuttke

tumor biologyprotein sciencemolecular medicinecell biologymedicinal researchtranscriptome changesmembrane biologygene functionmolecular biologypharmacologymolecular pharmacologyglucocorticoid receptor-rna bindingendocrinologypharmacological researchdexamethasone treatmentrna biologytherapeutic efficacy

Rna Binding by the Glucocorticoid Receptor Attenuates Dexamethasone-Induced Gene Activation. Scientific Reports (2023)

Nickolaus C. LammerHumza M. AshrafDaniella A. UgaySabrina L. SpencerMary A. AllenRobert T. BateyDeborah S. Wuttke

rna bindingmolecular pharmacologydexamethasone-induced gene activationgene functionmolecular regulationmolecular biologypharmacologyscientific dataglucocorticoid receptorrna biologygenetics

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Deborah Wuttke

Professor

University of Colorado Boulder

Affiliations

Natural Sciences

Biochemistry Department

College of Arts and Sciences

Natural Sciences

Deborah Wuttke is currently serving as a Biochemistry Professor at University of Colorado Boulder.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Deborah Wuttke

University of Colorado Boulder

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dna Affinity Driven Chromatin Dynamics Determine Estrogen Receptor α Transcriptional Activity Independent of Rna Binding. Research Square (2026)

Mecp2 Mbd-Id Module: A Unified Dna/Rna Binding Interface Disrupted in Rett Syndrome. bioRxiv (Cold Spring Harbor Laboratory) (2026)

The Canonical Rpa Complex Interacts With Est3 to Regulate Yeast Telomerase Activity. Proceedings of the National Academy of Sciences (2025)

A Distinct Mechanism of Rna Recognition by the Transcription Factor Gata1. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Daniella A. UgayRobert T. BateyDeborah S. Wuttke

rna recognitionmolecular recognitiontranscription factorstranscription (biology)molecular biologygene recognitiongene expressionrna biology

Guardians of the Genome: How the Single-Stranded Dna-Binding Proteins Rpa and Cst Facilitate Telomere Replication. Biomolecules (2024)

Conner L. OlsonDeborah S. Wuttke

dna replicationmolecular biologybiomolecules

The Rna-Binding Domain of Hnrnp U Extends Beyond the Rgg/Rg Motifs. Biochemistry (2024)

Otto A. KletzienDeborah S. WuttkeRobert T. Batey

rna-binding domaingene expressionmolecular biologybiochemistry

The Rna-Binding Selectivity of the Rgg/Rg Motifs of Hnrnp U is Abolished by Elements Within the C-Terminal Intrinsically Disordered Region. Journal of Molecular Biology (2024)

Otto A KletzienDeborah S WuttkeRobert T Batey

Transcription Factors Erα and Sox2 Have Differing Multiphasic Dna- and Rna-Binding Mechanisms. RNA (2024)

Wayne O HemphillHalley R SteinerJackson R KominskyDeborah S WuttkeThomas R Cech

transcription factors eratranscription factorsrna binding mechanismsmolecular biologymultiphasic dna

Quantification of Transcriptome Changes to Investigate the Role of Glucocorticoid Receptor-Rna Binding During Dexamethasone Treatment. BMC Research Notes (2023)

Nickolaus C. LammerMary A. AllenRobert T. BateyDeborah S. Wuttke

Rna Binding by the Glucocorticoid Receptor Attenuates Dexamethasone-Induced Gene Activation. Scientific Reports (2023)

Nickolaus C. LammerHumza M. AshrafDaniella A. UgaySabrina L. SpencerMary A. AllenRobert T. BateyDeborah S. Wuttke

rna bindingmolecular pharmacologydexamethasone-induced gene activationgene functionmolecular regulationmolecular biologypharmacologyscientific dataglucocorticoid receptorrna biologygenetics

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