Faculty

Institution

Unit

Venue

Gourisankar Ghosh

Professor

University of California, San Diego

Affiliations

Physical Sciences

Chemistry & Biochemistry

Gourisankar Ghosh is currently serving as a Chemistry & Biochemistry Professor at University of California, San Diego.

Honors

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Experiences

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Education

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Gourisankar Ghosh

University of California, San Diego

Professor

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molecular biology protein science genetics structural biology biochemistry gene expression cell signaling cell biology protein structure signal transduction tumor biology enzymes structural molecular biology molecular regulation molecular genetics biological chemistry protein phosphorylation transcription regulation gene regulation molecular cell biology rna biology cell regulation genome biology protein genetics enzyme inhibition medicinal research molecular structure mammalian biology nucleic acids crystal structures biomolecular structure oncogenes gene function biomolecular interactions yeast molecular science virus research molecular cancer protein function protein expression plo biology signaling pathways cellular biology structural bioinformatics protein chemistry gene recognition molecular docking molecular neurobiology x-ray crystallography cancer genetics x-ray crystal structure functional regulation molecular virology protein assembly molecular complexes protein x-ray crystallography nf-kb dimers structural basis sr protein phosphorylation nf-kb regulation sequence assembly developmental genetics epigenomics human retrovirus genome structure nf-kb signaling module alternative splicing processive phosphorylation nf-kb transcription factors distinct mechanisms transcriptional activity protein kinase protein kinases nf-kb signaling pathway transcriptional regulation nf-kb inactivation systems biology splicing variant rna processing mrna transport transcription (biology)

Notable Scholarly Works

Notable Federal Grants

Collaborators

Chromogranin a Deficiency Attenuates Tauopathy by Altering Epinephrine–Alpha-Adrenergic Receptor Signaling. Research Square (Research Square) (2024)

Sushil MahataSuborno JatiDaniel Munoz-MayorgaShandy ShahabiKechun TangYuren TaoDennis DicksonIrene LitvanGourisankar GhoshXu Chen

receptorsepilepsyhomeostatic mechanismsepinephrine-alpha-adrenergic receptorreceptor (biochemistry)neuropharmacologyendocrinologychromatinneurosciencepharmacologypsychoneuroendocrinologyhormonal receptorreceptor tyrosine kinasesmolecular biologymedicinal research

Cooperativity Among Clustered κB Sites Within Promoters and Enhancers Dictates Transcriptional Specificity of Nf-κB Rela Along With Specific Cofactors. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Shandy ShahabiTapan BiswasYuting ShenYaya ZouRose SanahmadiGourisankar Ghosh

molecular geneticscell biologyprotein sciencepharmacologyfunctional modificationgene expressiontumor biologyenzymestranscriptional specificitysequence motifmembrane biologyspecific cofactorsclustered kb sitesvirus researchmolecular cell biologyredox biologyprotein expressionfunctional selectivitytranscription regulationmolecular biologyenzyme inhibitionnf-kb rela

Cooperativity Among Clustered κB Sites Within Promoters and Enhancers Dictates Transcriptional Specificity of Nf-κB-Rela Along With Specific Cofactors. Research Square (Research Square) (2024)

Shandy ShahabiTapan BiswasYuting ShenRose SanahmadiYaya ZouGourisankar Ghosh

cell biologycell signalingprotein sciencegene expressionchromatinchromatin remodelinggene regulatory networkstranscriptional specificitysystems biologyspecific cofactorsclustered kb sitesgene structuremolecular cell biologytranscription (biology)transcription factorsnucleic acidsgene regulationtranscription regulationmolecular biology

Dual-Specific Autophosphorylation of Kinase Ikk2 Enables Phosphorylation of Substrate IκBα Through a Phosphoenzyme Intermediate. (2024)

Prateeka BorarTapan BiswasAnkur ChaudhuriTom HuxfordSaikat ChakrabartiGourisankar GhoshSmarajit Polley

tumor biologyprotein phosphorylationenzymesdual-specific autophosphorylationprotein scienceprotein engineeringbiochemistrypharmacologysubstrate ikbasignal transductionmolecular biologymedicinal researchphosphoenzyme intermediate

F2,6Bp Restores Mitochondrial Genome Integrity in Huntingtons Disease. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Anirban ChakrabortySanti M. MandalMikita MankevichSravan Gopalkrishnashetty SreenivasmurthyMuralidhar L. HegdeBalaji KrishnanGourisankar GhoshTapas Hazra

microbiologygeneticsgene expressionmolecular geneticshuntington's diseasechromosome biologymitochondrial genome integritygenomicsgenome biologymolecular biologyhuntingtons disease

Fructose-2,6-Bisphosphate Restores Dna Repair Activity of Pnkp and Ameliorates Neurodegenerative Symptoms in Huntington’s Disease. Proceedings of the National Academy of Sciences (2024)

Anirban ChakrabortySravan Gopalkrishnashetty SreenivasmurthyWyatt MillerWeihan HuaiTapan BiswasSanti Mohan MandalLisardo BoscáBalaji KrishnanGourisankar GhoshTapas Hazra

neurodegenerative symptomshuntington's diseaseneurodegenerative diseasesneurosciencebiochemistryrepair activitymolecular neurodegenerationdna repairmolecular biologydegenerative disease

Fructose-2,6-Bisphosphate Restores Tdp-43 Pathology-Driven Genome Repair Deficiency in Motor Neuron Diseases. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Joy MitraAnirban ChakrabortyVikas H. MalojiraoManohar KodavatiSanti M. MandalVelmarini VasquezMikita MankevichGourisankar GhoshMuralidhar L. HegdeTapas Hazra

molecular biologyneurodegenerative diseasesmotor disordersmotor neuron diseases

Hdx-Ms Analysis of Catalytic Activation of Ikk2 in the IκB Kinase Complex. Biochemistry (2024)

William SuryajayaTapan BiswasShandy ShahabiMatthew MealkaTom HuxfordGourisankar Ghosh

enzymescatalyst activationhdx-ms analysiscatalytic activationikb kinase complexbiochemistrysignal transductionmolecular biology

Phosphorylation-Induced Flexibility of Proto-Oncogenic Bcl3 Regulates Transcriptional Activation by Nf-κB P52 Homodimer. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Wenfei PanTapan BiswasShandy ShahabiWilliam SuryajayaAndres VasquezQian DuGourisankar GhoshVivien Ya-fan Wang

cancer biologyprotein sciencephosphorylation-induced flexibilitygene expressiontumor biologymembrane biologygeneticsmolecular cancertranscriptional activationtranscription (biology)transcription factorsredox biologybiochemistrygenome biologygene regulationoncogenestranscription regulationgene functionmolecular biologycancer genetics

Reviewer #2 (Public Review): Dual-Specific Autophosphorylation of Kinase Ikk2 Enables Phosphorylation of Substrate IκBα Through a Phosphoenzyme Intermediate. (2024)

Prateeka BorarTapan BiswasAnkur ChaudhuriTom HuxfordSaikat ChakrabartiGourisankar GhoshSmarajit Polley

dual-specific autophosphorylationprotein sciencecell signalingmolecular regulationpharmacologystructure-function enzyme kineticsmammalian biologymolecular physiologyenzymesmolecular biologymembrane biologyprotein phosphorylationbiochemistrysubstrate ikbaphosphoenzyme intermediateprotein functionmedicinal researchsignal transductionreceptor tyrosine kinasesprotein engineeringenzyme inhibitionpublic review

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Gourisankar Ghosh

Professor

University of California, San Diego

Affiliations

Physical Sciences

Chemistry & Biochemistry

Gourisankar Ghosh is currently serving as a Chemistry & Biochemistry Professor at University of California, San Diego.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Gourisankar Ghosh

University of California, San Diego

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Chromogranin a Deficiency Attenuates Tauopathy by Altering Epinephrine–Alpha-Adrenergic Receptor Signaling. Research Square (Research Square) (2024)

Sushil MahataSuborno JatiDaniel Munoz-MayorgaShandy ShahabiKechun TangYuren TaoDennis DicksonIrene LitvanGourisankar GhoshXu Chen

Shandy ShahabiTapan BiswasYuting ShenYaya ZouRose SanahmadiGourisankar Ghosh

Cooperativity Among Clustered κB Sites Within Promoters and Enhancers Dictates Transcriptional Specificity of Nf-κB-Rela Along With Specific Cofactors. Research Square (Research Square) (2024)

Shandy ShahabiTapan BiswasYuting ShenRose SanahmadiYaya ZouGourisankar Ghosh

Dual-Specific Autophosphorylation of Kinase Ikk2 Enables Phosphorylation of Substrate IκBα Through a Phosphoenzyme Intermediate. (2024)

Prateeka BorarTapan BiswasAnkur ChaudhuriTom HuxfordSaikat ChakrabartiGourisankar GhoshSmarajit Polley

F2,6Bp Restores Mitochondrial Genome Integrity in Huntingtons Disease. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Anirban ChakrabortySanti M. MandalMikita MankevichSravan Gopalkrishnashetty SreenivasmurthyMuralidhar L. HegdeBalaji KrishnanGourisankar GhoshTapas Hazra

microbiologygeneticsgene expressionmolecular geneticshuntington's diseasechromosome biologymitochondrial genome integritygenomicsgenome biologymolecular biologyhuntingtons disease

Fructose-2,6-Bisphosphate Restores Dna Repair Activity of Pnkp and Ameliorates Neurodegenerative Symptoms in Huntington’s Disease. Proceedings of the National Academy of Sciences (2024)

Anirban ChakrabortySravan Gopalkrishnashetty SreenivasmurthyWyatt MillerWeihan HuaiTapan BiswasSanti Mohan MandalLisardo BoscáBalaji KrishnanGourisankar GhoshTapas Hazra

neurodegenerative symptomshuntington's diseaseneurodegenerative diseasesneurosciencebiochemistryrepair activitymolecular neurodegenerationdna repairmolecular biologydegenerative disease

Fructose-2,6-Bisphosphate Restores Tdp-43 Pathology-Driven Genome Repair Deficiency in Motor Neuron Diseases. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Joy MitraAnirban ChakrabortyVikas H. MalojiraoManohar KodavatiSanti M. MandalVelmarini VasquezMikita MankevichGourisankar GhoshMuralidhar L. HegdeTapas Hazra

molecular biologyneurodegenerative diseasesmotor disordersmotor neuron diseases

Hdx-Ms Analysis of Catalytic Activation of Ikk2 in the IκB Kinase Complex. Biochemistry (2024)

William SuryajayaTapan BiswasShandy ShahabiMatthew MealkaTom HuxfordGourisankar Ghosh

enzymescatalyst activationhdx-ms analysiscatalytic activationikb kinase complexbiochemistrysignal transductionmolecular biology

Phosphorylation-Induced Flexibility of Proto-Oncogenic Bcl3 Regulates Transcriptional Activation by Nf-κB P52 Homodimer. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Wenfei PanTapan BiswasShandy ShahabiWilliam SuryajayaAndres VasquezQian DuGourisankar GhoshVivien Ya-fan Wang

Reviewer #2 (Public Review): Dual-Specific Autophosphorylation of Kinase Ikk2 Enables Phosphorylation of Substrate IκBα Through a Phosphoenzyme Intermediate. (2024)

Prateeka BorarTapan BiswasAnkur ChaudhuriTom HuxfordSaikat ChakrabartiGourisankar GhoshSmarajit Polley

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molecular biology

proteomics

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molecular research

molecular pathway

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