Faculty

Institution

Unit

Venue

Chris Vanderwal

Professor

University of California, Irvine

Affiliations

School of Physical Sciences

Department of Chemistry

Chris Vanderwal is currently serving as a Chemistry Professor at University of California, Irvine.

Honors

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Experiences

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Education

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Chris Vanderwal

University of California, Irvine

Professor

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chemistry organic synthesis organic chemistry chemical synthesis pharmacology biochemistry medicinal chemistry transition metal chemistry molecular biology chemical sciences catalysis natural product synthesis structural biology drug discovery enantioselective synthesis protein science structural chemistry synthetic chemistry organometallic catalysis natural products coordination chemistry zincke aldehydes natural product research biological chemistry medicinal research heterocyclic heterocycle chemistry tumor targeting redox chemistry concise synthesis short synthesis general chemistry molecular cancer biological inorganic chemistry phytochemistry peptide synthesis synthesis methods protein function stereoselective synthesis structure elucidation protein synthesis longest linear sequence chemical feasibility concise formal synthesis stereoselective halogenation postulated biogenesis zincke ring-opening biological relevance cellular biochemistry molecular physiology cellular physiology plant science molecular science brain tumor research proteinlipid interaction natural product biosynthesis halogenation conformational studies molecular catalysis pharmaceutical chemistry phycology plant biology catalytic synthesis cancer biology cancer genomics cancer treatment cancer genetics polymer synthesis oncogenic agent functional selectivity chemical rationalization direct precursor allylic alcohol derivatives stereoselective dichlorination cascade reactions intramolecular cycloadditions organic process research asymmetric catalysis

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents. Journal of the American Chemical Society (2024)

Griffin L. BarnesNicholas L. MagannDaniele PerrottaFabian M. HörmannSebastian FernandezPratap VydyamJae-Yeon ChoiJacques PrudhommeArmund NealKarine G. Le RochChoukri Ben MamounChristopher D. Vanderwal

antiprotozoal agentschemistrychemical synthesischemical sciencesorganic synthesisdivergent synthesis

A Fluorescence-Based Assay for Measuring Polyamine Biosynthesis Aminopropyl Transferase-Mediated Catalysis. Journal of Biological Chemistry (2024)

Pallavi SinghJae-Yeon ChoiWeiwei WangTukiet LamPhilip LechnerChristopher D VanderwalSovitj PouAaron NilsenChoukri Ben Mamoun

fluorescence spectroscopyprotein scienceenzyme catalysisbiochemical engineeringpeptide scienceenzymesbiological chemistryfluorescence-based assaychemical biologypolyamine biosynthesisfluorescencebiochemistryenzyme specificityprotein synthesismolecular metabolismbiomolecular engineeringstructural molecular biologytransferase-mediated catalysismolecular biologyexperimental biophysics

A Kalihinol Analog Disrupts Apicoplast Function and Vesicular Trafficking in P. Falciparum Malaria. Science (2024)

Z. ChahineS. AbelT. HollinG. L. BarnesJ. H. ChungM. E. DaubI. RenardJ. Y. ChoiP. VydyamA. PalM. Alba-ArgomanizC. A. S. BanksJ. KirkwoodA. SarafI. CaminoP. CastanedaM. C. CuevasJ. De Mercado-ArnanzE. Fernandez-AlvaroA. Garcia-PerezN. IbarzS. Viera-MorillaJ. PrudhommeC. J. JoynerA. K. BeiL. FlorensC. Ben MamounC. D. VanderwalK. G. Le Roch

microbiologyinfectious diseasesmalariaimmunologyintracellular traffickingtropical medicinevesicular traffickingcell trafficking

An Enantiospecific Synthesis of Isoneoamphilectane Confirms Its Strained Tricyclic Structure. Journal of the American Chemical Society (2023)

Natalie C. DwuletZeinab ChahineKarine G. Le RochChristopher D. Vanderwal

chemistryorganic chemistrychemical synthesisstrained tricyclic structureenantiospecific synthesisorganic synthesis

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

biophysicschemistrycrystal diffraction studycrystal engineeringcrystal researchcrystallographycrystal structuresccdc 2157502structure elucidationstructure determinationchemical structuredeposited datasetstructural chemistry

Enantioselective Syntheses of Wickerols a and B. Journal of the American Chemical Society (2023)

Jonathan ChungJoseph S. CapaniMatthias GöhlPhilipp C. RoosenChristopher D. Vanderwal

chemical synthesisorganic synthesischemistryenantioselective synthesis

Hydrogen‐Atom‐Transfer‐Initiated Radical/Polar Crossover Annulation Cascade for Expedient Access to Complex Tetralins. Angewandte Chemie International Edition (2023)

Lucas K. JohnsonGriffin L. BarnesSebastian A. FernandezChristopher D. Vanderwal

chemistrychemical synthesisorganic synthesisradical (chemistry)computational chemistrytransition metal chemistry

Lessons Learned: Asphyxiation Hazard Associated With Dry Ice. ACS Chemical Health & Safety (2023)

Bonnie J. ParkChristopher D. Vanderwal

chemistrydry icepublic healthchemical safetysafety sciencesafetychemical engineering

Stereocontrolled Access to Quaternary Centers by Birch Reduction/Alkylation of Chiral Esters of Salicylic Acids. The Journal of Organic Chemistry (2023)

Ryan A. KozlowskiHanh T. NguyenMichael E. LehmanChristopher D. Vanderwal

organic chemistrychiral estersquaternary centerssalicylic acidsstereocontrolled access

Synthesis of a Complex Brasilicardin Analogue Utilizing a Cobalt-Catalyzed Mhat-Induced Radical Bicyclization Reaction. Organic Letters (2023)

Scott W. NimanRoberta BuonoDavid A. FrumanChristopher D. Vanderwal

organic chemistrychemical synthesismedicinal chemistrysynthetic chemistryorganic synthesisbiochemistrypharmacologymolecular biologycomplex brasilicardin analoguecatalysis

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Chris Vanderwal

Professor

University of California, Irvine

Affiliations

School of Physical Sciences

Department of Chemistry

Chris Vanderwal is currently serving as a Chemistry Professor at University of California, Irvine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Chris Vanderwal

University of California, Irvine

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents. Journal of the American Chemical Society (2024)

antiprotozoal agentschemistrychemical synthesischemical sciencesorganic synthesisdivergent synthesis

A Fluorescence-Based Assay for Measuring Polyamine Biosynthesis Aminopropyl Transferase-Mediated Catalysis. Journal of Biological Chemistry (2024)

Pallavi SinghJae-Yeon ChoiWeiwei WangTukiet LamPhilip LechnerChristopher D VanderwalSovitj PouAaron NilsenChoukri Ben Mamoun

A Kalihinol Analog Disrupts Apicoplast Function and Vesicular Trafficking in P. Falciparum Malaria. Science (2024)

microbiologyinfectious diseasesmalariaimmunologyintracellular traffickingtropical medicinevesicular traffickingcell trafficking

An Enantiospecific Synthesis of Isoneoamphilectane Confirms Its Strained Tricyclic Structure. Journal of the American Chemical Society (2023)

Natalie C. DwuletZeinab ChahineKarine G. Le RochChristopher D. Vanderwal

chemistryorganic chemistrychemical synthesisstrained tricyclic structureenantiospecific synthesisorganic synthesis

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

Enantioselective Syntheses of Wickerols a and B. Journal of the American Chemical Society (2023)

Jonathan ChungJoseph S. CapaniMatthias GöhlPhilipp C. RoosenChristopher D. Vanderwal

chemical synthesisorganic synthesischemistryenantioselective synthesis

Hydrogen‐Atom‐Transfer‐Initiated Radical/Polar Crossover Annulation Cascade for Expedient Access to Complex Tetralins. Angewandte Chemie International Edition (2023)

Lucas K. JohnsonGriffin L. BarnesSebastian A. FernandezChristopher D. Vanderwal

chemistrychemical synthesisorganic synthesisradical (chemistry)computational chemistrytransition metal chemistry

Lessons Learned: Asphyxiation Hazard Associated With Dry Ice. ACS Chemical Health & Safety (2023)

Bonnie J. ParkChristopher D. Vanderwal

chemistrydry icepublic healthchemical safetysafety sciencesafetychemical engineering

Stereocontrolled Access to Quaternary Centers by Birch Reduction/Alkylation of Chiral Esters of Salicylic Acids. The Journal of Organic Chemistry (2023)

Ryan A. KozlowskiHanh T. NguyenMichael E. LehmanChristopher D. Vanderwal

organic chemistrychiral estersquaternary centerssalicylic acidsstereocontrolled access

Synthesis of a Complex Brasilicardin Analogue Utilizing a Cobalt-Catalyzed Mhat-Induced Radical Bicyclization Reaction. Organic Letters (2023)

Scott W. NimanRoberta BuonoDavid A. FrumanChristopher D. Vanderwal

organic chemistrychemical synthesismedicinal chemistrysynthetic chemistryorganic synthesisbiochemistrypharmacologymolecular biologycomplex brasilicardin analoguecatalysis

1
2
3
4
5
16
10 / page

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