Faculty

Institution

Unit

Venue

Jeffrey N. Johnston

Stevenson Professor of Chemistry

Vanderbilt University

Affiliations

College of Arts and Science

Chemistry

Graduate School

Chemistry

Jeffrey N. Johnston is currently serving as a Chemistry Stevenson Professor of Chemistry at Vanderbilt University.

Honors

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Experiences

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Education

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Jeffrey N. Johnston

Vanderbilt University

Stevenson Professor of Chemistry

You can click a keyword to filter the displayed items

chemistry organic synthesis organic chemistry chemical synthesis pharmacology enantioselective synthesis catalysis medicinal chemistry synthetic chemistry biochemistry chemical sciences chemical engineering drug discovery transition metal chemistry stereoselective synthesis asymmetric catalysis coordination chemistry organometallic chemistry enzyme inhibition peptide synthesis catalytic synthesis total synthesis receptors organic process research peptides cardiovascular research organometallic catalysis natural product synthesis electron-rich amines umpolung amide synthesis biological chemistry biomolecular structure catalyst activation molecular catalysis phytochemistry biocatalysis catalyst preparation cardiovascular physiology decagram scale chiral proton catalysis protein science cellular physiology molecular physiology redox biology sustainable chemistry experimental medicine enzyme catalysis melanoma anti-cancer agents mechanisms of action natural product biosynthesis achiral counterion control direct entry a-nitro esters chiral b-diketimines b-diamino acids material chemistry apoptosis cancer immunosurveillance tumor suppressors molecular communication intermittently connected device functional modification host-guest chemistry anaerobic digestion biomimetic chemistry energy homeostasis mitochondrial function integrative biology microbial physiology umpolung reactivity diastereoselective mukaiyama-michael reactions bronsted acid-catalyzed iodolactonization stilbene cis-diamines concise preparation bifunctional asymmetric catalysis natural product research bioorganic chemistry chemical biology biomolecular engineering cheminformatics

Notable Scholarly Works

Notable Federal Grants

Collaborators

Elucidating Fluorine Steering Effects in Diels‐Alder Reactions Interfaced With Charge‐Enhanced Reactivity. European Journal of Organic Chemistry (2025)

Sabrina HofordJulius JanJeffrey N. JohnstonTravis Dudding

interface chemistrychemical engineeringphysical organic chemistryorganic chemistrysurface reactivitytransition metal chemistryorganic synthesismolecular biologybiomolecular engineeringcatalysiscoordination chemistrydiels-alder reactionsorganometallic chemistryresidual stresssupramolecular chemistrycharge-enhanced reactivity

End-To-End Backbone Cyclization Enhances Passive Permeability of Bro5 Oligomeric Depsipeptides With Nonlinear Size Dependence. ACS Medicinal Chemistry Letters (2025)

Madelaine P. ThorpeCorey R. HopkinsJeffrey N. Johnston

nanoparticle researchtherapeutic targetsbiomolecular engineeringmacromolecular chemistrynonlinear size dependencemolecular biophysicsmedicinal chemistrypeptide engineeringprotein structurelarge scale structurepeptide sciencedrug discoverybiophysicspharmaceutical chemistrymolecular biologypeptidesbiological macromoleculesbioactive materialsbiomolecules

Performance-Enhancing Asymmetric Catalysis Driven by Achiral Counterion Design. Journal of the American Chemical Society (2025)

asymmetric catalysischemical engineeringchemical reaction engineeringachiral counterion designcatalysischemical scienceschemistry

Total Synthesis of Feglymycin Using Umpolung Amide Synthesis. Angewandte Chemie International Edition (2025)

medicinal chemistrypharmacologysynthetic chemistryorganic synthesispharmaceutical chemistrynatural product researchtotal synthesisorganic process researchnatural product synthesischemical synthesis

Backbone-Determined Antiarrhythmic Structure–Activity Relationships for a Mirror Image, Oligomeric Depsipeptide Natural Product. Journal of Medicinal Chemistry (2024)

Madelaine P. ThorpeDaniel J. BlackwellBjorn C. KnollmannJeffrey N. Johnston

medicinal chemistrypharmacologynatural productsdrug discoverymirror imagebiomolecular engineering

Ccdc 2287760: Experimental Crystal Structure Determination. The Cambridge Structural Database (2024)

crystal researchchemical structurestructural biologycrystal structuresstructural chemistrystructure determinationcrystal engineeringcrystallographystructure elucidationccdc 2287760chemistry

Ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2-/- Mice. Biophysical Journal (2024)

Aaron GochmanTri Q. DoKyungsoo KimJacob SchwarzMadelaine P. ThorpeDaniel BlackwellAbigail N. SmithWendell S. AkersRazvan L. CorneaDerek R. LaverJeffrey N. JohnstonBjorn C. Knollmann

pharmacologybiophysical chemistryreceptorsbiophysicsneuroscienceryanodine receptor channelscell signalingneuropharmacologymammalian biologyelectrophysiology

Generality-Driven Catalyst Development: A Universal Catalyst for Enantioselective Nitroalkene Reduction. Journal of the American Chemical Society (2024)

Zihang DengMelanie A. PadalinoJulius E. L. JanSangjun ParkMichael W. DannemanJeffrey N. Johnston

sustainable chemistrychemical engineeringcatalytic synthesisgenerality-driven catalyst developmentcatalyst preparationgreen chemistrycatalysisindustrial catalysismolecular catalysisenantioselective nitroalkene reductionuniversal catalyst

Ent -Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2 −/− Mice. Molecular Pharmacology (2024)

Aaron GochmanTri Q. DoKyungsoo KimJacob A. SchwarzMadelaine P. ThorpeDaniel J. BlackwellPaxton A. RitschelAbigail N. SmithRobyn T. RebbeckWendell S. AkersRazvan L. CorneaDerek R. LaverJeffrey N. JohnstonBjorn C. Knollmann

geneticspharmacologyreceptorsmedicinegene expressionsignal transductionenzyme inhibitionryanodine receptor channelscell signalingneuromodulation (medicine)molecular pharmacologymammalian biologyinhibitory activity

The Backbone Constitution Drives Passive Permeability Independent of Side Chains in Depsipeptide and Peptide Macrocycles. Chem. Sci. (2024)

membrane biologybiomolecular structurebiophysicspeptide scienceproteinlipid interactionpeptide synthesispeptide macrocyclesbiochemistrybiomolecular engineeringmembrane proteinspeptidesside chainsbiomolecules

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Jeffrey N. Johnston

Stevenson Professor of Chemistry

Vanderbilt University

Affiliations

College of Arts and Science

Chemistry

Graduate School

Chemistry

Jeffrey N. Johnston is currently serving as a Chemistry Stevenson Professor of Chemistry at Vanderbilt University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jeffrey N. Johnston

Vanderbilt University

Stevenson Professor of Chemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Elucidating Fluorine Steering Effects in Diels‐Alder Reactions Interfaced With Charge‐Enhanced Reactivity. European Journal of Organic Chemistry (2025)

Sabrina HofordJulius JanJeffrey N. JohnstonTravis Dudding

End-To-End Backbone Cyclization Enhances Passive Permeability of Bro5 Oligomeric Depsipeptides With Nonlinear Size Dependence. ACS Medicinal Chemistry Letters (2025)

Madelaine P. ThorpeCorey R. HopkinsJeffrey N. Johnston

Performance-Enhancing Asymmetric Catalysis Driven by Achiral Counterion Design. Journal of the American Chemical Society (2025)

asymmetric catalysischemical engineeringchemical reaction engineeringachiral counterion designcatalysischemical scienceschemistry

Total Synthesis of Feglymycin Using Umpolung Amide Synthesis. Angewandte Chemie International Edition (2025)

medicinal chemistrypharmacologysynthetic chemistryorganic synthesispharmaceutical chemistrynatural product researchtotal synthesisorganic process researchnatural product synthesischemical synthesis

Backbone-Determined Antiarrhythmic Structure–Activity Relationships for a Mirror Image, Oligomeric Depsipeptide Natural Product. Journal of Medicinal Chemistry (2024)

Madelaine P. ThorpeDaniel J. BlackwellBjorn C. KnollmannJeffrey N. Johnston

medicinal chemistrypharmacologynatural productsdrug discoverymirror imagebiomolecular engineering

Ccdc 2287760: Experimental Crystal Structure Determination. The Cambridge Structural Database (2024)

crystal researchchemical structurestructural biologycrystal structuresstructural chemistrystructure determinationcrystal engineeringcrystallographystructure elucidationccdc 2287760chemistry

Ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2-/- Mice. Biophysical Journal (2024)

Aaron GochmanTri Q. DoKyungsoo KimJacob SchwarzMadelaine P. ThorpeDaniel BlackwellAbigail N. SmithWendell S. AkersRazvan L. CorneaDerek R. LaverJeffrey N. JohnstonBjorn C. Knollmann

pharmacologybiophysical chemistryreceptorsbiophysicsneuroscienceryanodine receptor channelscell signalingneuropharmacologymammalian biologyelectrophysiology

Generality-Driven Catalyst Development: A Universal Catalyst for Enantioselective Nitroalkene Reduction. Journal of the American Chemical Society (2024)

Zihang DengMelanie A. PadalinoJulius E. L. JanSangjun ParkMichael W. DannemanJeffrey N. Johnston

Ent -Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2 −/− Mice. Molecular Pharmacology (2024)

The Backbone Constitution Drives Passive Permeability Independent of Side Chains in Depsipeptide and Peptide Macrocycles. Chem. Sci. (2024)

1
2
3
4
5
17
10 / page

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University of Virginia

pharmacology

organic synthesis

Rajeev Prabhakar

Institution

University of Miami

biochemistry

enzymes

Robin Polt

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University of Arizona

lipid chemistry

biomolecular engineering

Barry Snider

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general chemistry

Daniel Romo

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chemistry

Keith Woerpel

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