Faculty

Institution

Unit

Venue

Roger F. Duncan

Associate Professor of Pharmacology and Pharmaceutical Sciences

University of Southern California

Affiliations

Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences

Department of Pharmacology and Pharmaceutical Sciences

Roger F. Duncan is currently serving as an Alfred E. Mann School Of Pharmacy And Pharmaceutical Sciences Associate Professor of Pharmacology and Pharmaceutical Sciences at University of Southern California.

Honors

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Experiences

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Education

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Roger F. Duncan

University of Southern California

Associate Professor of Pharmacology and Pharmaceutical Sciences

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biochemistry molecular biology cell biology genetics protein science biological chemistry protein synthesis gene expression mammalian biology virology cell signaling insect molecular biology membrane biology protein phosphorylation molecular regulation rna biology structural biology enzymes cellular physiology redox biology molecular physiology hela cells translational repression heat shock translational control oxidative stress signal transduction biochemical sciences cell regulation transcription regulation liver physiology respiratory medicine nucleic acids insect biochemistry free radical biology translational physiology heat recovery virus-host interactions protein genetics dna sequencing protein function heat shock effects serum depletion initiation factors efficient translation cell death genome biology avian biology protein transport mitochondrial function viral genetics viral hepatitis genome sequencing functional recovery remedial action thermal therapies thermal management epigenetic changes molecular adaptation heme transport heme trafficking heme degradation heme homeostasis heme signaling redox signaling gene regulation protein expression gene function initiation factor modifications heat stress mitochondrion-dependent apoptosis brain mitochondria function jnk signalling c-jun n-terminal kinase covalent modification transcription-regulatory region apoptosis heat shock proteins

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 5513: Discovery of an Orally Active Small-Molecule Irreversible Inhibitor of Protein Disulfide Isomerase (Pdi) for Ovarian Cancer Treatment.. Cancer Research (2013)

Shili XuAlexey N. ButkevichRoppei YamadaYu ZhouBikash DebnathRoger DuncanEbrahim ZandiNicos A. PetasisNouri Neamati

cancer biologypharmacologyenzymesprotein disulfide isomeraseoncologycancer researchcancer carecancer treatmentcancer discoverydrug discoveryovarian cancer treatmentanti-cancer agentsovarian cancermedicinal researchpharmaceutical chemistrybiomolecular engineeringcancer managementmolecular biologyenzyme inhibitionpharmacotherapy

Rapamycin Conditionally Inhibits Hsp90 but Not Hsp70 Mrna Translation in Drosophila: Implications for the Mechanisms of Hsp Mrna Translation. Cell Stress and Chaperones (2008)

Roger F. Duncan

geneticsgene expressionprotein sciencecell signalingmolecular regulationhsp mrna translationpharmacologyrna biologyprotein expressiongene functiontranscription regulationmolecular biologyenzyme inhibition

Inhibition of Hsp90 Function Delays and Impairs Recovery From Heat Shock. FEBS Journal (2005)

Roger F Duncan

thermal therapieswound healingthermal managementremedial actionheat recoveryneurosciencefunctional recoveryrespiratory medicinephysiologycritical careimpairs recoverystress (biology)heat shock

The Induction of the Heat Shock Response as Well as Its Termination is Autoregulated by Heat Shock Protein Activities. Free Radical Biology and Medicine (2005)

biochemical sciencesmolecular and cellular biologymolecular cell biologycell signalingprotein scienceheat shock responseprotein chemistrybiological chemistrybiochemistryphysiologysignal transductionmolecular biologyprotein function

Altered Traffic of Disease–Related Autoantigens During an Aberrant Membrane Traffic Program in Rabbit Lacrimal Acinar Cells.. Investigative ophthalmology & visual science (2004)

R.M. HawkL. QianC.M. RoseR. DuncanA.K. Mircheff

disease-related autoantigensdermatologyophthalmology

Signal Transduction Pathways Leading to Increased Eif4E Phosphorylation Caused by Oxidative Stress. Free Radical Biology and Medicine (2004)

Roger F. DuncanHazel PetersonAlex Sevanian

protein phosphorylationmedicinesignal transduction pathwaysoxidative stresscell signalingredox biologyfree radical biologysignal transductionredox signaling

Translational Regulation of Hsp90 Mrna. Journal of Biological Chemistry (2004)

Ruhi AhmedRoger F. Duncan

geneticsbiological chemistrybiochemistrymembrane biologytranslational regulationmolecular biology

C-Jun N-Terminal Kinase (Jnk)-Mediated Modulation of Brain Mitochondria Function: New Target Proteins for Jnk Signalling in Mitochondrion-Dependent Apoptosis. Biochemical Journal (2003)

Hagen SCHROETERClinton S. BOYDRuhi AHMEDJeremy P. E. SPENCERRoger F. DUNCANCatherine RICE-EVANSEnrique CADENAS

biochemical sciencesmitochondrial functionc-jun n-terminal kinasecell signalingmitochondrion-dependent apoptosisneurosciencebiochemistrymembrane biologybrain mitochondria functionjnk signallingmolecular biologyprotein functioncell death

Heme and Lipid Peroxides in Hemoglobin-Modified Low-Density Lipoprotein Mediate Cell Survival and Adaptation to Oxidative Stress. Blood (2003)

Liana AsatryanOuliana ZiouzenkovaRoger DuncanAlex Sevanian

lipid peroxidesheme degradationcell biologyfree radical biologyliver physiologyoxidative stresshuman biologymembrane biologycell metabolismheme traffickingredox biologyheme homeostasisbiochemistryheme signalingphysiologyhematologyregenerative medicineheme transportcellular physiology

Oxidative Stress Increases Eukaryotic Initiation Factor 4E Phosphorylation in Vascular Cells. Biochemical Journal (2003)

Roger F. DUNCANHazel PETERSONCurt H. HAGEDORNAlex SEVANIAN

biochemical sciencesoxidative stressdermatologycell biologyredox biologyvascular cellsbiochemistryvascular biologycellular physiology

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Roger F. Duncan

Associate Professor of Pharmacology and Pharmaceutical Sciences

University of Southern California

Affiliations

Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences

Department of Pharmacology and Pharmaceutical Sciences

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Roger F. Duncan

University of Southern California

Associate Professor of Pharmacology and Pharmaceutical Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 5513: Discovery of an Orally Active Small-Molecule Irreversible Inhibitor of Protein Disulfide Isomerase (Pdi) for Ovarian Cancer Treatment.. Cancer Research (2013)

Shili XuAlexey N. ButkevichRoppei YamadaYu ZhouBikash DebnathRoger DuncanEbrahim ZandiNicos A. PetasisNouri Neamati

Rapamycin Conditionally Inhibits Hsp90 but Not Hsp70 Mrna Translation in Drosophila: Implications for the Mechanisms of Hsp Mrna Translation. Cell Stress and Chaperones (2008)

Roger F. Duncan

Inhibition of Hsp90 Function Delays and Impairs Recovery From Heat Shock. FEBS Journal (2005)

Roger F Duncan

thermal therapieswound healingthermal managementremedial actionheat recoveryneurosciencefunctional recoveryrespiratory medicinephysiologycritical careimpairs recoverystress (biology)heat shock

The Induction of the Heat Shock Response as Well as Its Termination is Autoregulated by Heat Shock Protein Activities. Free Radical Biology and Medicine (2005)

Altered Traffic of Disease–Related Autoantigens During an Aberrant Membrane Traffic Program in Rabbit Lacrimal Acinar Cells.. Investigative ophthalmology & visual science (2004)

R.M. HawkL. QianC.M. RoseR. DuncanA.K. Mircheff

disease-related autoantigensdermatologyophthalmology

Signal Transduction Pathways Leading to Increased Eif4E Phosphorylation Caused by Oxidative Stress. Free Radical Biology and Medicine (2004)

Roger F. DuncanHazel PetersonAlex Sevanian

protein phosphorylationmedicinesignal transduction pathwaysoxidative stresscell signalingredox biologyfree radical biologysignal transductionredox signaling

Translational Regulation of Hsp90 Mrna. Journal of Biological Chemistry (2004)

Ruhi AhmedRoger F. Duncan

geneticsbiological chemistrybiochemistrymembrane biologytranslational regulationmolecular biology

C-Jun N-Terminal Kinase (Jnk)-Mediated Modulation of Brain Mitochondria Function: New Target Proteins for Jnk Signalling in Mitochondrion-Dependent Apoptosis. Biochemical Journal (2003)

Hagen SCHROETERClinton S. BOYDRuhi AHMEDJeremy P. E. SPENCERRoger F. DUNCANCatherine RICE-EVANSEnrique CADENAS

Heme and Lipid Peroxides in Hemoglobin-Modified Low-Density Lipoprotein Mediate Cell Survival and Adaptation to Oxidative Stress. Blood (2003)

Liana AsatryanOuliana ZiouzenkovaRoger DuncanAlex Sevanian

Oxidative Stress Increases Eukaryotic Initiation Factor 4E Phosphorylation in Vascular Cells. Biochemical Journal (2003)

Roger F. DUNCANHazel PETERSONCurt H. HAGEDORNAlex SEVANIAN

biochemical sciencesoxidative stressdermatologycell biologyredox biologyvascular cellsbiochemistryvascular biologycellular physiology

1
2
3
4
5
10 / page

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stem cell

cancer cell

Gerald Shadel

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University of California, San Diego

molecular biology

genetics

Joan Heller Brown

Institution

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cam kinase

brain tumor research

Lawrence Grossman

Institution

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molecular metabolism

metabolism

Xiongwei Zhu

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health science

biomedical informatics

Ganes C. Sen

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viral pathogenesis

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cell biology

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physiology

endocrinology

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health science

cardiovascular translational research

Neil Osheroff

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dna sequencing

molecular biology