Faculty

Institution

Unit

Venue

Joan Heller Brown

Distinguished Professor & Past Chair Program Director NIH T32 in Pharmacological Sciences

University of California, San Diego

Affiliations

School Of Medicine

Pharmacology

Joan Heller Brown is currently serving as a Pharmacology Distinguished Professor & Past Chair Program Director NIH T32 in Pharmacological Sciences at University of California, San Diego.

Honors

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Experiences

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Education

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Joan Heller Brown

University of California, San Diego

Distinguished Professor & Past Chair Program Director NIH T32 in Pharmacological Sciences

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cardiology physiology molecular biology cell biology cardiovascular research cell signaling biochemistry signal transduction cardiovascular physiology gene expression molecular physiology membrane biology cellular physiology inflammation vascular biology circulatory physiology receptors biological chemistry electrophysiology signaling pathways cardiac muscle medicinal research protein science g protein-coupled receptor cell regulation mammalian biology mitochondrial function molecular cell biology cell death cardiomyopathy liver physiology redox biology molecular regulation cardiac pathologies enzyme inhibition respiratory medicine cardiovascular pharmacology protein phosphorylation animal physiology receptor tyrosine kinases apoptosis reperfusion injury cancer biology receptor (biochemistry) cardiovascular function transcription regulation protein function cardiac mechanics astrocytoma cells redox signaling human physiology inhibitory activity clinical physiology gene regulation intracellular trafficking mammalian physiology phosphoinositide hydrolysis cardiac myocytes myocardial infarction functional regulation angiogenesis respiratory neurobiology cardiac hypertrophy muscarinic receptors cell physiology calcium mobilization cyclic amp formation cardiac function mitochondrial death pathway ventricular myocytes gaq signaling cardiac myocyte apoptosis adult rat cardiomyocytes b-adrenergic receptor phospholipase ce muscarinic receptor activation pharmacology gliomas cam kinase brain tumor research molecular cancer molecular pharmacology tumor growth

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract Mo137: Modulation of the Inflammatory and Fibrotic Effects of Angiotensin on Cardiomyocytes Through Yap-Mediated Transcription.. Circulation Research (2024)

Van NinhCameron BrandMelissa BarlowSidar AydinJamie FranciscoDominic Del ReJoan Heller Brown

biochemistrycell biologymolecular physiologymechanobiologybiomolecular engineeringcardiomyopathycirculatory physiologyvascular biologygene expressioninflammationcardiovascular researchreactive oxygen speciescardiologyfibrotic effectscardiovascular translational researchg protein-coupled receptorcardiovascular pharmacologycell signalingmedicinal researchyap-mediated transcription

Ca2+/Calmodulin‐Dependent Kinase IiδC‐Induced Chronic Heart Failure Does Not Depend on Sarcoplasmic Reticulum Ca2+ Leak. ESC Heart Failure (2024)

Matthias DewenterTilmann SeitzJulia H. SteinbrecherB. Daan WestenbrinkHaiyun LingStephan E. LehnartXander H.T. WehrensJohannes BacksJoan Heller BrownLars S. MaierStefan Neef

health sciencescardiovascular diseasecardiologycardiac pathologiesheart failure

A Kinase Interacting Protein 1 (Akip1) Promotes Cardiomyocyte Elongation and Physiological Cardiac Remodelling. Scientific Reports (2023)

Kirsten T. NijholtPablo I. Sánchez-AguileraHarmen G. BooijSilke U. Oberdorf-MaassMartin M. DokterAnouk H. G. WoltersBen N. G. GiepmansWiek H. van GilstJoan H. BrownRudolf A. de BoerHerman H. W. SilljéB. Daan Westenbrink

cardiovascular physiologyphysiological cardiac remodellingcardiomyocyte elongationcardiologymechanobiologymolecular biologycell biologyphysiology

Gα12 Signaling Regulates Transcriptional and Phenotypic Responses That Promote Glioblastoma Tumor Invasion. Scientific Reports (2023)

Olga Meiri ChaimShunichiro MikiBriana C. PragerJianhui MaAnthony Y. JeongJacqueline LaraNancy K. TranJeffrey M. SmithJeremy N. RichJ. Silvio GutkindShigeki MiyamotoFrank B. FurnariJoan Heller Brown

scientific datacell regulationgeneticscancer biologymolecular cancercancer researchneuroscienceneuro-oncologyphenotypic responsesmolecular cell biologygene expressiononcologybrain tumor researchcancer geneticsimmunologysignaling pathwaysglioblastoma tumor invasionhost responsecell signalingmedicinal research

Nitric Oxide Modulates Ca 2+ Leak and Arrhythmias via S-Nitrosylation of Camkii. Circulation Research (2023)

Amelia S. PowerEsther U. AsamudoLuke P.I. WorthingtonChidera C. AlimRaquel E. ParackalRachel S. WallaceObialunanma V. EbenebeJoan Heller BrownMark J. KohrDonald M. BersJeffrey R. Erickson

neurologyrespiratory medicinecardiologyneurosciencerespiratory neurobiologyelectrophysiologyphysiology

Nitric Oxide Modulates Spontaneous Ca 2+ Release and Ventricular Arrhythmias During β-Adrenergic Signalling Through S -Nitrosylation of Calcium/Calmodulin Dependent Kinase II. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Amelia S. PowerEsther AsamudoLuke P. I. WorthingtonChidera C. AlimRaquel ParackalRachel S. WallaceObialunanma V. EbenebeJoan Heller BrownMark J. KohrDonald M. BersJeffrey R. Erickson

pharmacologycardiologyneuroscienceventricular arrhythmiasbiochemistrynitric oxideneuropharmacologyneurophysiologyelectrophysiology

Effects of Mango and Mint Pod-Based E-Cigarette Aerosol Inhalation on Inflammatory States of the Brain, Lung, Heart, and Colon in Mice. eLife (2022)

Alex MoshenskyCameron S BrandHasan AlhaddadJohn ShinJorge A Masso-SilvaIra AdvaniDeepti GungeAditi SharmaSagar MehtaArya JahanSedtavut NilaadJarod OlayWanjun GuTatum SimonsonDaniyah AlmarghalaniJosephine PhamSamantha PereraKenneth ParkRita Al-KollaHoyoung MoonSoumita DasMin Kwang ByunZahoor ShahYoussef SariJoan Heller BrownLaura E Crotty Alexander

neurologypharmacologypulmonary diseasesrespiratory medicineinflammationrespiratory toxicologyaerosol sciencechronic inflammationregulatory toxicologyhealth effectsphytotherapy researchinhalation toxicologymedicinal researchcardiovascular diseaseinflammatory stateselectrophysiologyphysiology

Regulation of Glioblastoma Stem Cell Properties and Tumor Invasion by G ⍺12 Signaling. The FASEB Journal (2022)

Olga M. ChaimShunichiro MikiFrank FurnariShigeki MiyamotoJoan H. Brown

surgical oncologycell regulationcancer biologycancer researchneuroscienceneuro-oncologycancer genomicstumor biologyneurologycancer treatmentoncologybrain tumor researchsignaling pathwaysstem cell researchcancer caretumor invasionradiation oncologycell signalingmedicinal research

Rhoa Signaling Increases Mitophagy and Protects Cardiomyocytes Against Ischemia by Stabilizing Pink1 Protein and Recruiting Parkin to Mitochondria. Cell Death and Differentiation (2022)

Michelle TuValerie P. TanJustin D. YuRaghav TripathiZahna BighamMelissa BarlowJeffrey M. SmithJoan Heller BrownShigeki Miyamoto

membrane biologymitochondrial functiongene expressionsignal transductionmammalian biologyliver physiologycardiologyneuroscienceheme homeostasiscellular physiologyprotein functiondeath studiescell signalingmitophagycell regulationcell biologycell deathphysiology

Splicing and Dicing: A Deeper Dive Into Camkiiδ and Cardiac Inflammation. Circulation Research (2022)

Joan Heller BrownShigeki Miyamoto

health sciencesmedicineinflammationrespiratory medicinecardiologycardiac inflammationphysiology

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Joan Heller Brown

Distinguished Professor & Past Chair Program Director NIH T32 in Pharmacological Sciences

University of California, San Diego

Affiliations

School Of Medicine

Pharmacology

Joan Heller Brown is currently serving as a Pharmacology Distinguished Professor & Past Chair Program Director NIH T32 in Pharmacological Sciences at University of California, San Diego.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Joan Heller Brown

University of California, San Diego

Distinguished Professor & Past Chair Program Director NIH T32 in Pharmacological Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract Mo137: Modulation of the Inflammatory and Fibrotic Effects of Angiotensin on Cardiomyocytes Through Yap-Mediated Transcription.. Circulation Research (2024)

Van NinhCameron BrandMelissa BarlowSidar AydinJamie FranciscoDominic Del ReJoan Heller Brown

Ca2+/Calmodulin‐Dependent Kinase IiδC‐Induced Chronic Heart Failure Does Not Depend on Sarcoplasmic Reticulum Ca2+ Leak. ESC Heart Failure (2024)

Matthias DewenterTilmann SeitzJulia H. SteinbrecherB. Daan WestenbrinkHaiyun LingStephan E. LehnartXander H.T. WehrensJohannes BacksJoan Heller BrownLars S. MaierStefan Neef

health sciencescardiovascular diseasecardiologycardiac pathologiesheart failure

A Kinase Interacting Protein 1 (Akip1) Promotes Cardiomyocyte Elongation and Physiological Cardiac Remodelling. Scientific Reports (2023)

cardiovascular physiologyphysiological cardiac remodellingcardiomyocyte elongationcardiologymechanobiologymolecular biologycell biologyphysiology

Gα12 Signaling Regulates Transcriptional and Phenotypic Responses That Promote Glioblastoma Tumor Invasion. Scientific Reports (2023)

Olga Meiri ChaimShunichiro MikiBriana C. PragerJianhui MaAnthony Y. JeongJacqueline LaraNancy K. TranJeffrey M. SmithJeremy N. RichJ. Silvio GutkindShigeki MiyamotoFrank B. FurnariJoan Heller Brown

Nitric Oxide Modulates Ca 2+ Leak and Arrhythmias via S-Nitrosylation of Camkii. Circulation Research (2023)

Amelia S. PowerEsther U. AsamudoLuke P.I. WorthingtonChidera C. AlimRaquel E. ParackalRachel S. WallaceObialunanma V. EbenebeJoan Heller BrownMark J. KohrDonald M. BersJeffrey R. Erickson

neurologyrespiratory medicinecardiologyneurosciencerespiratory neurobiologyelectrophysiologyphysiology

Amelia S. PowerEsther AsamudoLuke P. I. WorthingtonChidera C. AlimRaquel ParackalRachel S. WallaceObialunanma V. EbenebeJoan Heller BrownMark J. KohrDonald M. BersJeffrey R. Erickson

pharmacologycardiologyneuroscienceventricular arrhythmiasbiochemistrynitric oxideneuropharmacologyneurophysiologyelectrophysiology

Effects of Mango and Mint Pod-Based E-Cigarette Aerosol Inhalation on Inflammatory States of the Brain, Lung, Heart, and Colon in Mice. eLife (2022)

Regulation of Glioblastoma Stem Cell Properties and Tumor Invasion by G ⍺12 Signaling. The FASEB Journal (2022)

Olga M. ChaimShunichiro MikiFrank FurnariShigeki MiyamotoJoan H. Brown

Rhoa Signaling Increases Mitophagy and Protects Cardiomyocytes Against Ischemia by Stabilizing Pink1 Protein and Recruiting Parkin to Mitochondria. Cell Death and Differentiation (2022)

Michelle TuValerie P. TanJustin D. YuRaghav TripathiZahna BighamMelissa BarlowJeffrey M. SmithJoan Heller BrownShigeki Miyamoto

Splicing and Dicing: A Deeper Dive Into Camkiiδ and Cardiac Inflammation. Circulation Research (2022)

Joan Heller BrownShigeki Miyamoto

health sciencesmedicineinflammationrespiratory medicinecardiologycardiac inflammationphysiology

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gpcr expression

Daria Mochly-Rosen

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