Faculty

Institution

Unit

Venue

R John Solaro

Distinguished University Professor

University of Illinois Chicago

Affiliations

College of Medicine

Department of Physiology and Biophysics

R John Solaro is currently serving as a College Of Medicine Distinguished University Professor at University of Illinois Chicago.

Honors

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Experiences

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Education

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R John Solaro

University of Illinois Chicago

Distinguished University Professor

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cardiology physiology pharmacology cardiovascular research cardiovascular physiology biochemistry molecular biology circulatory physiology electrophysiology cellular physiology molecular physiology animal physiology membrane biology mammalian biology cardiac muscle protein science cell signaling applied physiology protein phosphorylation structural biology cardiomyopathy signal transduction gene expression vascular biology biological chemistry mammalian physiology human physiology cardiovascular function endocrinology cardiovascular pharmacology protein function respiratory medicine medicinal research muscle function biochemical sciences veterinary physiology cellular biochemistry skeletal muscle medical biophysics experimental biophysics physiological regulation signaling pathways redox biology physiological research enzyme inhibition cardiac myofilaments protein transport brain circulation molecular regulation cell motility diastolic function familial hypertrophic cardiomyopathy redox signaling tissue physiology cardiac myocytes cardiac function cell biomechanics biological function cardiac contractility receptor (biochemistry) cell physiology biochemical genetics protein expression translational physiology sarcoplasmic reticulum atpase activity hypertrophic cardiomyopathy cardiac troponin biological inorganic chemistry protein kinase myofilament proteins myofilament calcium sensitivity myofilament response acidic ph differential effects cardiac myofibrils mechanobiology cell biology cardiac dynamics endothelial dysfunction

Notable Scholarly Works

Notable Federal Grants

Collaborators

A New Era of Understanding of the Control of Thick Filament States in the Heartbeat. Proceedings of the National Academy of Sciences (2025)

biophysicscardiac mechanicscirculatory physiologyelectrophysiological evaluationcardiovascular physiologyelectrophysiologyneurosciencethick filament statesphysiologyneurophysiologynew eranervous systembiophysical reviewcardiac muscle

Ca2+ Sensitivity Changes in Skinned Myocardial Fibers Induced by Myosin–Actin Crossbridge-Independent Sarcomere Stretch: Role of N-Domain of Mybp-C. Journal of Molecular and Cellular Cardiology (2025)

Xutu WangNathan KallishR John SolaroWen-Ji Dong

cardiac mechanicscell biologycardiovascular researchcutaneous biologycirculatory physiologymechanobiologybiomedical engineeringmatrix biologyskinned myocardial fiberscytoskeletonvascular biologyphysiologymyocardial infarctionfibrosisinflammationcardiologyextracellular matrixcellular physiologycardiac muscle

Mechano- and Inflammatory-Signaling Alterations in Hearts of a Porcine Hcm Model Harboring a β-Myosin Heavy Chain (Myh7-R403Q) Gene Mutation. Journal of Molecular and Cellular Cardiology Plus (2025)

cardiomyopathycirculatory physiologyinflammatory-signaling alterationsgene mutationcardiovascular physiologycell biologycell signalingmolecular cell biologymechanobiologyporcine hcm modelcardiac pathologiesphysiologysignal transductioncardiovascular researchdisease pathophysiologycellular physiologymolecular physiologycardiac muscle

Myosin-Actin Crossbridge Independent Sarcomere Length Induced Ca2+ Sensitivity Changes in Skinned Myocardial Fibers: Role of Myosin Heads. Journal of Molecular and Cellular Cardiology (2025)

Xutu WangR John SolaroWen-Ji Dong

skeletal musclecell biologyfiberscirculatory physiologymechanobiologyskinned myocardial fiberscytoskeletonbone researchimmunologyvascular biologyphysiologytissue (biology)intermediate hostmyocardial infarctionmyosin-actin crossbridgemyosin headscardiologyextracellular matrixcellular physiologymicrovascular dysfunctioncardiac muscle

Reduction in Myofilament Ca2+ Sensitivity Partially Ameliorates the Cardiac Phenotype in Hypertrophic Cardiomyopathy Linked to a Tnt-R92Q Mutation. Frontiers in Physiology (2025)

cardiomyopathycirculatory physiologymyositiscardiologycardiac phenotypetnt-r92q mutationphysiologycardiovascular researchmolecular biologymyofilament ca2+ sensitivitymolecular physiologycardiac muscle

P21 ‐Activated Kinase 1 (Pak1) as an Element in Functional and Dysfunctional Interplay Among the Myocardium, Adipose Tissue, and Pancreatic Beta Cells. Comprehensive physiology (2025)

adipose tissuesignaling pathwaysmolecular and cellular biologycell regulationpancreatic beta cellscell biologycell signalingmolecular cell biologyphysiologysignal transductionkinase 1cell metabolismcellular physiologymolecular physiologycellular biochemistry

The 14-3-3Gamma Interactome Integrates Changes in Myofilament Mechanotransduction With the Metabolic Machinery in the Heart. Journal of Molecular and Cellular Cardiology Plus (2025)

metabolic machinerymetabolismmolecular metabolismcirculatory physiologyskeletal muscleapplied physiologytranslational physiologymetabolic remodelingmechanobiologysystems biologymyofilament mechanotransductionphysiologysignal transductionmechanotransductioncell metabolismcellular physiologymolecular physiologycardiac muscle

Editorial Board. Brachytherapy (2024)

A SyedMichael ZelefskyBethany AndersonGastrointestinal StrnadSteven FrankMatthew HarkenriderMitchell KamravaEye HeadPhillip DevlinChirag ShahGilad CohenMark RivardInvited FeaturesScott GlaserUsa TheranosticsNeil TaunkJaroslaw HepelJean Michael Hannoun-LeviFrance GastrointestinalPeter HassAlexandra StewartAmandeep TaggarMira KeyesGerard MortonPeter OrioChad TangEmma FieldsEric LeungWilliam SmallNeck SkinAngeles RovirosaLuca TagliaferriNikhil JoshiMartin TomAntonio DamatoChristopher DeufelDaniel ScanderbegDavid Aramburu NúñezIvan BuzurovicMauricio CambeiroMark CorkumJean-Marc CossetBrett CoxJuanita CrookJoao LuisDa SilvaBrian DavisLaura DoylePatricia EifelShirin EngerGabriel FonsecaRazvan GalalaeJose GuinotChristina GutiérrezLara HathoutEric HorwitzPeter HoskinJun ItamiChristian KirisitsManon KisselMarisa KollmeierRajat KudchadkerUsama MahmoodPatrick MclaughlinKevin MartellCanada Victor Munoz-GarzonBradley PietersCsaba PolgarAron PopovtzerLouis PottersBradley PrestidgeMarcus RandallSusan RichardsonMack RoachSimona ShaitelmanFrank-Andre SiebertNelson StoneEric VigneaultAkila ViswanathanTe VuongJunjie WangChina WernickeCatheryn YasharAtsunori YoruzuDavid Newcombe

Emerging Concepts of Mechanisms Controlling Cardiac Tension: Focus on Familial Dilated Cardiomyopathy (Dcm) and Sarcomere-Directed Therapies. Biomedicines (2024)

R. SolaroPaul GoldspinkBeata Wolska

geneticsmedicinecardiac tensioncardiologysarcomere-directed therapiesbiomedical researchbiomedical engineeringclinical researchmedicinal research

The Role of Cardiac Troponin and Other Emerging Biomarkers Among Athletes and Beyond: Underlying Mechanisms, Differential Diagnosis, and Guide for Interpretation. Biomolecules (2024)

Mihail CeleskiAndrea SegretiFilippo CrisciRiccardo CriccoMariagrazia PiscioneGiuseppe Di GioiaAnnunziata NuscaChiara FossatiFabio PigozziGian Paolo UssiaRoss John SolaroFrancesco Grigioni

underlying mechanismscardiac troponinathletic trainingsystems biologybiochemistrybiomoleculesphysiological measurementsstress biomarkerscardiac pathologiescardiovascular researchmolecular biologybiological functionexercise physiologybiomarkers

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R John Solaro

Distinguished University Professor

University of Illinois Chicago

Affiliations

College of Medicine

Department of Physiology and Biophysics

R John Solaro is currently serving as a College Of Medicine Distinguished University Professor at University of Illinois Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

R John Solaro

University of Illinois Chicago

Distinguished University Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A New Era of Understanding of the Control of Thick Filament States in the Heartbeat. Proceedings of the National Academy of Sciences (2025)

Xutu WangNathan KallishR John SolaroWen-Ji Dong

Myosin-Actin Crossbridge Independent Sarcomere Length Induced Ca2+ Sensitivity Changes in Skinned Myocardial Fibers: Role of Myosin Heads. Journal of Molecular and Cellular Cardiology (2025)

Xutu WangR John SolaroWen-Ji Dong

Reduction in Myofilament Ca2+ Sensitivity Partially Ameliorates the Cardiac Phenotype in Hypertrophic Cardiomyopathy Linked to a Tnt-R92Q Mutation. Frontiers in Physiology (2025)

P21 ‐Activated Kinase 1 (Pak1) as an Element in Functional and Dysfunctional Interplay Among the Myocardium, Adipose Tissue, and Pancreatic Beta Cells. Comprehensive physiology (2025)

The 14-3-3Gamma Interactome Integrates Changes in Myofilament Mechanotransduction With the Metabolic Machinery in the Heart. Journal of Molecular and Cellular Cardiology Plus (2025)

Editorial Board. Brachytherapy (2024)

Emerging Concepts of Mechanisms Controlling Cardiac Tension: Focus on Familial Dilated Cardiomyopathy (Dcm) and Sarcomere-Directed Therapies. Biomedicines (2024)

R. SolaroPaul GoldspinkBeata Wolska

geneticsmedicinecardiac tensioncardiologysarcomere-directed therapiesbiomedical researchbiomedical engineeringclinical researchmedicinal research

The Role of Cardiac Troponin and Other Emerging Biomarkers Among Athletes and Beyond: Underlying Mechanisms, Differential Diagnosis, and Guide for Interpretation. Biomolecules (2024)

Mihail CeleskiAndrea SegretiFilippo CrisciRiccardo CriccoMariagrazia PiscioneGiuseppe Di GioiaAnnunziata NuscaChiara FossatiFabio PigozziGian Paolo UssiaRoss John SolaroFrancesco Grigioni

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cardiovascular translational research

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