Faculty

Institution

Unit

Venue

Lawrence Grossman

Professor and Director

Wayne State University

Lawrence Grossman is currently serving as a Professor and Director at Wayne State University.

Honors

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Experiences

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Education

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Lawrence Grossman

Wayne State University

Professor and Director

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molecular biology genetics biochemistry mammalian biology genomics membrane biology evolutionary biology molecular genetics gene expression genome biology redox biology enzymes mitochondrial function molecular evolution structural biology liver physiology protein science molecular physiology bioenergetics human genetics avian biology protein genetics yeast molecular regulation biological chemistry cellular physiology cytogenetics gene function gene structure rna biology animal physiology obstetrics and gynaecology protein evolution evolutionary genetics apoptosis cancer biology nucleic acids animal science primatology reperfusion injury maternal-fetal medicine cell death biological evolution animal genetics fetal medicine cell regulation neonatology gene regulation anthropoid primates yeast mitochondrial dna human disease adaptive evolution molecular cell biology neurochemistry mitochondrial dna cellular neurobiology brain science protein synthesis dna sequencing cellular biology dna analysis protein function sequence analysis gene characterization protein expression nucleotide sequence mitochondrial respiration molecular mechanisms agarose gels placental mammals global ischemia cdna clone subunit iv subunit viic structural organization mitochondrial oxidative phosphorylation metabolism molecular metabolism mitochondrial diseases disease gene identification mitochondrial genetics pharmacology cell metabolism molecular medicine

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Mitochondrial Regulator Protein, Mnrr1, is Elevated in the Maternal Blood of Women With Preeclampsia. The Journal of Maternal-Fetal & Neonatal Medicine (2024)

Manaphat SuksaiRoberto RomeroMariachiara BoscoFrancesca GotschEunjung JungPiya ChaemsaithongAdi L. TarcaDereje W. GudichaNardhy Gomez-LopezMarcia Arenas-HernandezArun MeyyazhaganLawrence I. GrossmanSiddhesh ArasTinnakorn Chaiworapongsa

gynecologymitochondrial functionmedicineobstetrics and gynaecologyneonatologymaternal-fetal medicinematernal healthwomen's healthmitochondrial regulator proteinhealth sciencesfetal medicinematernal blood

Author Correction: To Boldly Go Where No Micrornas Have Gone Before: Spaceflight Impact on Risk for Small-For-Gestational-Age Infants. Communications Biology (2024)

Giada CortiJangKeun KimFrancisco J EnguitaJoseph W GuarnieriLawrence I GrossmanSylvain V CostesMatias FuentealbaRyan T ScottAndrea MagriniLauren M SandersKanhaiya SinghChandan K SenCassandra M JuranAmber M PaulDavid FurmanJean Calleja-AgiusChristopher E MasonDiego GaleanoMassimo BottiniAfshin Beheshti

early life exposuresspaceflight impactbiologypublic healthmortalityhealth sciencessmall-for-gestational-age infants

Er-Tethered Stress Sensor Crebh Regulates Mitochondrial Unfolded Protein Response to Maintain Energy Homeostasis. Proceedings of the National Academy of Sciences (2024)

Hyunbae KimQi ChenDonghong JuNeeraja PurandareXuequn ChenLobelia SamavatiLi LiRen ZhangLawrence I. GrossmanKezhong Zhang

molecular biologyprotein foldingenergy homeostasisstress (biology)

Mitochondrial Cytochrome C Oxidase Subunit 4 Isoform 2 (Cox4I2) Promotes Hypoxia-Induced Reduction of the Electron Transport System in Pulmonary Arterial Smooth Muscle Cells. Biochimica et Biophysica Acta (BBA) - Bioenergetics (2024)

Luca GiordanoIlka WittigAnika Nolte-GrütznerAlfredo Cabrera-OreficeSandipan JashOleg PakFenja KnoeppKerstin RamserJoel WahlPetr PecinaWerner SeegerNorbert WeissmannLawrence I. GrossmanMaik HüttemannNatascha Sommer

biophysicsmitochondrial functionhypoxia (medicine)cardiologyelectron transport systemprotein sciencehypoxia-induced reductionredox biologybiochemistrymembrane biologyfree radical biologyphysiologybioelectrochemistrycellular physiologymolecular physiology

Mitochondrial Cytochrome C Oxidase Subunit 4 Isoform 2 Regulates T-Cell Activation and Inflammation During Viral Infection. Biochimica et Biophysica Acta (BBA) - Bioenergetics (2024)

Vidya Srokshna Balasubramanian LakshmiThilo BergerClaudia GarciaSara VölkelJulian BetterMohammad EstiriLuca GiordanoClaudio NardielloWerner SeegerOleg PakUlrich MattSusanne HeroldLawrence I. GrossmanMaik HüttemannNorbert WeissmannChrysanthi SkevakiNatascha Sommer

virologyt-cell activationinflammationcell biologybioenergeticsimmunologyphysiologyviral infection

Pseudohypoxia-Stabilized Hif2⍺ Transcriptionally Inhibits Mnrr1, a Druggable Target in Melas. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Neeraja PurandareVignesh PasupathiYue XiVikram RajanCaleb VeghSteven FirestineTamas KoziczAndrew M. FribleyLawrence I. GrossmanSiddhesh Aras

transcription (biology)transcription factorsbiologybiochemistrymolecular biology

Regulation of Mitochondrial Oxidative Phosphorylation Through Tight Control of Cytochrome C Oxidase in Health and Disease – Implications for Ischemia/Reperfusion Injury, Inflammatory Diseases, Diabetes, and Cancer. Redox Biology (2024)

Lucynda PhamTasnim ArroumJunmei WanLauren PavelichJamie BellPaul T MorseIcksoo LeeLawrence I GrossmanThomas H SandersonMoh H MalekMaik Hüttemann

mitochondrial functiondiabetesreactive oxygen speciesfree radical biologymitochondrial oxidative phosphorylationmetabolismtight controloxidative stresssystems biologycell metabolismredox biologybiochemistryredox signalingmolecular metabolisminflammationsignal transductionreperfusion injurymolecular biologyenzyme inhibitionmitochondrial biogenesis

Resonance Raman Spectral Analysis of the Heme Site Structure of Cytochrome C Oxidase With Its Positive Regulator Chchd2. Journal of Inorganic Biochemistry (2024)

Sachiko YanagisawaTakuto KameiAtsuhiro ShimadaStephanie GladyckSiddhesh ArasMaik HüttemannLawrence I GrossmanMinoru Kubo

biophysicsenzymesbiological inorganic chemistrybiochemistryheme site structuremolecular biologystructural biology

To Boldly Go Where No Micrornas Have Gone Before: Spaceflight Impact on Risk for Small-For-Gestational-Age Infants. Communications Biology (2024)

developmental biologygeneticspediatricsspaceflight impactmicrorna detectionneonatologychild developmentsmall-for-gestational-age infants

Clinical Chorioamnionitis at Term is Characterized by Changes in the Plasma Concentration of Chchd2/Mnrr1, a Mitochondrial Protein. The Journal of Maternal-Fetal & Neonatal Medicine (2023)

Mariachiara BoscoRoberto RomeroDahiana M. GalloManaphat SuksaiFrancesca GotschEunjung JungPiya ChaemsaithongAdi L. TarcaNardhy Gomez-LopezMarcia Arenas-HernandezArun MeyyazhaganMalek Al QasemMassimo P. FranchiLawrence I. GrossmanSiddhesh ArasTinnakorn Chaiworapongsa

hematologyplasma concentrationmedicineobstetrics and gynaecologymaternal-fetal medicinepediatricsmaternal healthmitochondrial proteinrespiratory medicinemammalian biologyclinical chorioamnionitisneonatologyfetal medicineepidemiology

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Lawrence Grossman

Professor and Director

Wayne State University

Lawrence Grossman is currently serving as a Professor and Director at Wayne State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Lawrence Grossman

Wayne State University

Professor and Director

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Mitochondrial Regulator Protein, Mnrr1, is Elevated in the Maternal Blood of Women With Preeclampsia. The Journal of Maternal-Fetal & Neonatal Medicine (2024)

Author Correction: To Boldly Go Where No Micrornas Have Gone Before: Spaceflight Impact on Risk for Small-For-Gestational-Age Infants. Communications Biology (2024)

early life exposuresspaceflight impactbiologypublic healthmortalityhealth sciencessmall-for-gestational-age infants

Er-Tethered Stress Sensor Crebh Regulates Mitochondrial Unfolded Protein Response to Maintain Energy Homeostasis. Proceedings of the National Academy of Sciences (2024)

Hyunbae KimQi ChenDonghong JuNeeraja PurandareXuequn ChenLobelia SamavatiLi LiRen ZhangLawrence I. GrossmanKezhong Zhang

molecular biologyprotein foldingenergy homeostasisstress (biology)

Mitochondrial Cytochrome C Oxidase Subunit 4 Isoform 2 Regulates T-Cell Activation and Inflammation During Viral Infection. Biochimica et Biophysica Acta (BBA) - Bioenergetics (2024)

virologyt-cell activationinflammationcell biologybioenergeticsimmunologyphysiologyviral infection

Pseudohypoxia-Stabilized Hif2⍺ Transcriptionally Inhibits Mnrr1, a Druggable Target in Melas. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Neeraja PurandareVignesh PasupathiYue XiVikram RajanCaleb VeghSteven FirestineTamas KoziczAndrew M. FribleyLawrence I. GrossmanSiddhesh Aras

transcription (biology)transcription factorsbiologybiochemistrymolecular biology

Lucynda PhamTasnim ArroumJunmei WanLauren PavelichJamie BellPaul T MorseIcksoo LeeLawrence I GrossmanThomas H SandersonMoh H MalekMaik Hüttemann

Resonance Raman Spectral Analysis of the Heme Site Structure of Cytochrome C Oxidase With Its Positive Regulator Chchd2. Journal of Inorganic Biochemistry (2024)

Sachiko YanagisawaTakuto KameiAtsuhiro ShimadaStephanie GladyckSiddhesh ArasMaik HüttemannLawrence I GrossmanMinoru Kubo

biophysicsenzymesbiological inorganic chemistrybiochemistryheme site structuremolecular biologystructural biology

To Boldly Go Where No Micrornas Have Gone Before: Spaceflight Impact on Risk for Small-For-Gestational-Age Infants. Communications Biology (2024)

developmental biologygeneticspediatricsspaceflight impactmicrorna detectionneonatologychild developmentsmall-for-gestational-age infants

Clinical Chorioamnionitis at Term is Characterized by Changes in the Plasma Concentration of Chchd2/Mnrr1, a Mitochondrial Protein. The Journal of Maternal-Fetal & Neonatal Medicine (2023)

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