Faculty

Institution

Unit

Venue

Lee Bardwell

Professor Vice Chair

University of California, Irvine

Affiliations

School of Biological Sciences

Department of Developmental and Cell Biology

Lee Bardwell is currently serving as a Developmental And Cell Biology Professor Vice Chair at University of California, Irvine.

Honors

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Experiences

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Education

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Lee Bardwell

University of California, Irvine

Professor Vice Chair

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molecular biology genetics cell signaling biochemistry gene expression protein science yeast cell biology signal transduction dna repair enzymes protein function structural biology mammalian biology membrane biology signaling pathways molecular regulation molecular docking transcription (biology) genome biology molecular cell biology biological chemistry biochemical sciences enzyme inhibition transcription regulation protein phosphorylation mitogen-activated protein kinase biomolecular interactions protein chemistry cell regulation molecular physiology gene function protein expression nucleotide excision repair molecular science gene regulation pheromone response pathway high-affinity interaction cognate mapks mapk kinases dna helicase multisite phosphorylation saccharomyces cerevisiae stem cell research theoretical biology avian biology system science nucleic acids structural molecular biology experimental medicine cell lineage embryonic development host-microbe interactions gene evolution host specificity signal recognition breeding behavior biological function biochemical interaction recombination dynamic molecular biotechnology fungal cell biology molecular microbiology biochemical genetics molecular substrates rna biology protein purification protein genetics gene characterization extraembryonic lineages dual roles multiprotein complex specific cleavage repair intermediates model recombination invasive growth gene regulatory networks pathway analysis protein kinases

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cyclin B3 is a Dominant Fast-Acting Cyclin That Drives Rapid Early Embryonic Mitoses. The Journal of Cell Biology (2024)

Pablo Lara-GonzalezSmriti VariyarShabnam MogharehAnh Cao Ngoc NguyenAmrutha KizhedathuJacqueline BudrewiczAleesa SchlientzNeha VarshneyAndrew BellaartKaren OegemaLee BardwellArshad Desai

developmental biologygene expressioncell biologycytogeneticsmolecular biology

Mitogen-Activated Protein Kinase (Mapk) Cascades—a Yeast Perspective. The Enzymes (2023)

Lee BardwellJeremy Thorner

yeast perspectivegeneticsyeastcell signalingbiochemistrymitogen-activated protein kinasemolecular biology

The Ww Domain of Iqgap1 Binds Directly to the P110α Catalytic Subunit of Pi 3-Kinase. Biochemical Journal (2023)

A. Jane BardwellMadhuri PaulKiku C. YonedaMaría D. Andrade-LudeñaOanh T. NguyenDavid A. FrumanLee Bardwell

biochemical sciencesenzymesprotein sciencecell signalingprotein structuremembrane proteinsbiochemistrypharmacologyww domainmolecular biologyprotein functionstructural biology

Erk2 Map Kinase Regulates Sufu Binding by Multisite Phosphorylation of Gli1. Life Science Alliance (2022)

A Jane BardwellBeibei WuKavita Y SarinMarian L WatermanScott X AtwoodLee Bardwell

developmental biologyepigeneticsgeneticstumor biologyprotein phosphorylationcell regulationsufu bindingprotein sciencecell signalingneurosciencemolecular regulationprotein functionmammalian biologysignal transductiontranscription regulationgene expressionenzyme inhibitionmultisite phosphorylation

The Hippo Pathway Kinases Lats1 and Lats2 Attenuate Cellular Responses to Heavy Metals Through Phosphorylating Mtf1. Nature Cell Biology (2022)

Han HanHiroki J. NakaokaLine HofmannJeff Jiajing ZhouClinton YuLisha ZengJunyu NanGayoung SeoRebecca Elizabeth VargasBing YangRuxi QiLee BardwellDmitry A. FishmanKen W. Y. ChoLan HuangRay LuoRahul WarriorWenqi Wang

avian biologyprotein phosphorylationgene expressionheavy metalscell biologycell signalingimmunologymembrane biologymolecular biologyhippo pathway

Cancer Mutations: Molecular Mekanisms. Current Biology (2020)

Lee Bardwell

molecular mekanismscancer biologybiologycancer mutationsmolecular biology

PSEUDOKINASES: Flipping the Atp for Ampylation. Current Biology (2019)

Lee Bardwell

protein phosphorylationenzymesprotein biosynthesisprotein scienceenzyme catalysisstructural molecular biologybiologybiochemistrymolecular biologyenzyme inhibition

Miles to Go (Mtgo) Encodes Fndc3 Proteins That Interact With the Chaperonin Subunit Cct3 and Are Required for Nmj Branching and Growth in Drosophila. Developmental Biology (2018)

Adeela SyedTamás LukacsovichMiles PomeroyA. Jane BardwellGentry Thomas DeckerKatrina G. WaymireJudith PurcellWeijian HuangJames GuiEmily M. PadillaCindy ParkAntor PaulThai Bin T. PhamYanete RodriguezStephen WeiShane WorthgeRonak ZebarjediBing ZhangLee BardwellJ. Lawrence MarshGrant R. MacGregor

developmental biologygeneticsnmj branching

The Ww Domain of the Scaffolding Protein Iqgap1 is Neither Necessary nor Sufficient for Binding to the Mapks Erk1 and Erk2. Journal of Biological Chemistry (2017)

A. Jane BardwellLeonila LagunesRonak ZebarjediLee Bardwell

geneticsprotein scienceprotein structurebiologyww domainmolecular biologystructural biology

Crosstalk Between Map Kinase and Hedgehog Pathways by Direct Phosphorylation of Gli Transcription Factors. The FASEB Journal (2016)

Lee BardwellA Jane BardwellBeibei WuMarian Waterman

gli transcription factorsepigeneticsgeneticstumor biologygene expressionmap kinasecell regulationmolecular neurosciencedirect phosphorylationgene regulatory networksneurosciencemolecular regulationmembrane biologymammalian biologytranscription regulationhedgehog pathwaysmolecular biology

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Lee Bardwell

Professor Vice Chair

University of California, Irvine

Affiliations

School of Biological Sciences

Department of Developmental and Cell Biology

Lee Bardwell is currently serving as a Developmental And Cell Biology Professor Vice Chair at University of California, Irvine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Lee Bardwell

University of California, Irvine

Professor Vice Chair

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cyclin B3 is a Dominant Fast-Acting Cyclin That Drives Rapid Early Embryonic Mitoses. The Journal of Cell Biology (2024)

Pablo Lara-GonzalezSmriti VariyarShabnam MogharehAnh Cao Ngoc NguyenAmrutha KizhedathuJacqueline BudrewiczAleesa SchlientzNeha VarshneyAndrew BellaartKaren OegemaLee BardwellArshad Desai

developmental biologygene expressioncell biologycytogeneticsmolecular biology

Mitogen-Activated Protein Kinase (Mapk) Cascades—a Yeast Perspective. The Enzymes (2023)

Lee BardwellJeremy Thorner

yeast perspectivegeneticsyeastcell signalingbiochemistrymitogen-activated protein kinasemolecular biology

The Ww Domain of Iqgap1 Binds Directly to the P110α Catalytic Subunit of Pi 3-Kinase. Biochemical Journal (2023)

A. Jane BardwellMadhuri PaulKiku C. YonedaMaría D. Andrade-LudeñaOanh T. NguyenDavid A. FrumanLee Bardwell

biochemical sciencesenzymesprotein sciencecell signalingprotein structuremembrane proteinsbiochemistrypharmacologyww domainmolecular biologyprotein functionstructural biology

Erk2 Map Kinase Regulates Sufu Binding by Multisite Phosphorylation of Gli1. Life Science Alliance (2022)

A Jane BardwellBeibei WuKavita Y SarinMarian L WatermanScott X AtwoodLee Bardwell

The Hippo Pathway Kinases Lats1 and Lats2 Attenuate Cellular Responses to Heavy Metals Through Phosphorylating Mtf1. Nature Cell Biology (2022)

avian biologyprotein phosphorylationgene expressionheavy metalscell biologycell signalingimmunologymembrane biologymolecular biologyhippo pathway

Cancer Mutations: Molecular Mekanisms. Current Biology (2020)

Lee Bardwell

molecular mekanismscancer biologybiologycancer mutationsmolecular biology

PSEUDOKINASES: Flipping the Atp for Ampylation. Current Biology (2019)

Lee Bardwell

protein phosphorylationenzymesprotein biosynthesisprotein scienceenzyme catalysisstructural molecular biologybiologybiochemistrymolecular biologyenzyme inhibition

Miles to Go (Mtgo) Encodes Fndc3 Proteins That Interact With the Chaperonin Subunit Cct3 and Are Required for Nmj Branching and Growth in Drosophila. Developmental Biology (2018)

developmental biologygeneticsnmj branching

The Ww Domain of the Scaffolding Protein Iqgap1 is Neither Necessary nor Sufficient for Binding to the Mapks Erk1 and Erk2. Journal of Biological Chemistry (2017)

A. Jane BardwellLeonila LagunesRonak ZebarjediLee Bardwell

geneticsprotein scienceprotein structurebiologyww domainmolecular biologystructural biology

Crosstalk Between Map Kinase and Hedgehog Pathways by Direct Phosphorylation of Gli Transcription Factors. The FASEB Journal (2016)

Lee BardwellA Jane BardwellBeibei WuMarian Waterman

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Similar Faculty Members

Jeremy Thorner

Institution

University of California, Berkeley

signaling pathway

phosphoinositide-dependent signaling

Gourisankar Ghosh

Institution

University of California, San Diego

mrna transport

gene expression

Andrew Emili

Institution

Boston University

interactomics

biomedical informatics

Ian G. Macara

Institution

Vanderbilt University

breast cancer

cancer initiation

Shelley Berger

Institution

University of Pennsylvania

developmental biology

chromatin

Alexander J. Varshavsky

Institution

California Institute of Technology

ubiquitin conjugation

proteome research

Chao Zhang

Institution

University of Southern California

general chemistry

fine chemical

Michael B. Yaffe

Institution

Massachusetts Institute of Technology

immunology

dna damage response

Philip A. Cole

Institution

Johns Hopkins University

molecular biology

biochemistry

Nicola C. Partridge

Institution

New York University

parathyroid gland

pharmacological research