Faculty

Institution

Unit

Venue

Chao Zhang

Associate Professor of Chemistry

University of Southern California

Affiliations

Natural Sciences

Chemistry

College of Letters, Arts and Sciences

Natural Sciences

Chao Zhang is currently serving as a Chemistry Associate Professor of Chemistry at University of Southern California.

Honors

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Experiences

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Education

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Chao Zhang

University of Southern California

Associate Professor of Chemistry

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molecular biology pharmacology cell biology cell signaling genetics signal transduction drug discovery molecular cell biology gene expression protein science enzyme inhibition medicinal chemistry oncogenes medicinal research tumor biology signaling pathways cell regulation enzymes molecular cancer biological chemistry anti-cancer agents protein phosphorylation structural biology molecular physiology pharmacotherapy cancer treatment yeast receptor tyrosine kinases cancer biology cancer genetics drug targeting transcription regulation virus research leukemia cellular therapy cancer discovery molecular regulation gene regulation structural molecular biology chemical genetics tumor targeting receptor (biochemistry) cancer genomics gene function drug development inhibitory activity molecular neurobiology protein function rna biology mammalian biology general virology melanoma protein expression rna polymerase ii tumor suppressors cellular biology pathway analysis brain science neural science pharmaceutical sciences chemical genetic analysis protein kinases raf inhibitors skin cancer protein assembly kinase activity meiotic recombination enzyme recruitment transit system security games opportunistic criminals multi-agent diverse team raf dimers braf-mutant melanoma clinical efficacy erk signalling general chemistry chemical biology biochemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

Mono- and Difluoromethylation of 3(2 H )-Pyridazinones. Organic Letters (2024)

Ziyue ZhuJiaqi TangSamantha KyriazakosAlexander KniebYijie XuChao ZhangG. K. Surya Prakash

natural productsorganic chemistryheterocycle chemistrytransition metal chemistryorganic synthesisbioactive compoundschemical synthesischemistry

Raf Inhibitors Activate the Integrated Stress Response by Direct Activation of Gcn2. bioRxiv (Cold Spring Harbor Laboratory) (2024)

pharmacological researchpharmacologydrug discoveryoncogenesintegrated stress responsemechanisms of actiondirect activationbiochemistryg protein-coupled receptorcell signalingraf inhibitorsmolecular regulationtherapeutic targets

Alkyne as a Latent Warhead to Covalently Target Sars-Cov-2 Main Protease. Journal of Medicinal Chemistry (2023)

Chau NgoWilliam FriedSaba AliyariJoshua FengChao QinShilei ZhangHanjing YangJean ShanaaPinghui FengGenhong ChengXiaojiang S. ChenChao Zhang

medicinal chemistrypharmacologysars-cov-2medicinedrug discoverymolecular medicinelatent warheadvirus researchmolecular biologytranslational medicinemedicinal researchantiviral research

Bgs-2456 is a Novel Potent Covalent Inhibitor of Flt3 That Highly Discriminates Against Kit and is Not Toxic Toward Normal Hematopoiesis in Vitro. Blood (2023)

Ariel Leyte-VidalStacey PhanPrachi KhareFeiFei HuChao ZhangPing CaoNeil P. Shah

pharmacologymedicinal chemistryhealth sciencesmedicinedrug discoverydrug resistancehaematopoiesisclinical chemistryhematology

Development of Highly Fluorogenic Styrene Probes for Visualizing Rna in Live Cells. ACS Chemical Biology (2023)

Moon Jung KimYida LiJason A. JungeNathan K. KimScott E. FraserChao Zhang

membrane biologymolecular imagingfluorogenic styrene probesrna biologybiological chemistrychemical biotechnologyredox biologydevelopmental biologymolecular biologytranscriptomics technologylive cellsdirect observationcell biologybiological imagingchemical biologyfluorescence

Identification of Covalent Ligands – From Single Targets to Whole Proteome. Israel Journal of Chemistry (2023)

Chau NgoArunika EkanayakeChao Zhang

proteomicssingle-molecule detectionproteome researchbiochemistrycovalent ligandssingle targetschemistry

Structural and Functional Analyses of a Germline Kras T50I Mutation Provide Insights Into Raf Activation. JCI Insight (2023)

Pan-Yu ChenBenjamin J HuangMax HarrisChristopher BooneWeijie WangHeidi CariasBrian MesionaDaniela MavriciAmanda C KohlerGideon BollagChao ZhangYing ZhangKevin Shannon

structural biologymolecular biologyraf activation

Reactivity-Based Chemical-Genetic Study of Protein Kinases. RSC Medicinal Chemistry (2022)

Renata Rezende MirandaChao Zhang

geneticsmedicinal chemistryreactivity-based chemical-genetic studyprotein kinases

Sars-Cov-2 Couples Evasion of Inflammatory Response to Activated Nucleotide Synthesis. Proceedings of the National Academy of Sciences (2022)

Chao QinYouliang RaoHao YuanTing-Yu WangJun ZhaoBianca EspinosaYongzhen LiuShu ZhangAli Can SavasQizhi LiuMehrnaz ZarinfarStephanie RiceJill HenleyLucio ComaiNicholas A. GrahamCasey ChenChao ZhangPinghui Feng

geneticspharmacologysars-cov-2gene expressionvirologyinflammationmedical virologyvirus researchimmunologymedicinal researchmolecular virologyinflammatory responsegeneral virology

Abstract P156: Identification of Previously Unknown Targets for Approved Small-Molecule Drugs Using Chemoproteomic Platform Imtactm. Molecular Cancer Therapeutics (2021)

Vivian ZhangCindy HuangChao ZhangPing Cao

pharmacologymedicinal chemistrymolecular cancercancer treatmentmedicinedrug discoveryunknown targetsapproved small-molecule drugscancer researchproteomicsoncologypharmaceutical researchcancer genomicsdrug targetingpharmacotherapymedicinal researchdrug developmentchemoproteomic platform imtactm

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Chao Zhang

Associate Professor of Chemistry

University of Southern California

Affiliations

Natural Sciences

Chemistry

College of Letters, Arts and Sciences

Natural Sciences

Chao Zhang is currently serving as a Chemistry Associate Professor of Chemistry at University of Southern California.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Chao Zhang

University of Southern California

Associate Professor of Chemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Mono- and Difluoromethylation of 3(2 H )-Pyridazinones. Organic Letters (2024)

Ziyue ZhuJiaqi TangSamantha KyriazakosAlexander KniebYijie XuChao ZhangG. K. Surya Prakash

natural productsorganic chemistryheterocycle chemistrytransition metal chemistryorganic synthesisbioactive compoundschemical synthesischemistry

Raf Inhibitors Activate the Integrated Stress Response by Direct Activation of Gcn2. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Alkyne as a Latent Warhead to Covalently Target Sars-Cov-2 Main Protease. Journal of Medicinal Chemistry (2023)

Chau NgoWilliam FriedSaba AliyariJoshua FengChao QinShilei ZhangHanjing YangJean ShanaaPinghui FengGenhong ChengXiaojiang S. ChenChao Zhang

medicinal chemistrypharmacologysars-cov-2medicinedrug discoverymolecular medicinelatent warheadvirus researchmolecular biologytranslational medicinemedicinal researchantiviral research

Bgs-2456 is a Novel Potent Covalent Inhibitor of Flt3 That Highly Discriminates Against Kit and is Not Toxic Toward Normal Hematopoiesis in Vitro. Blood (2023)

Ariel Leyte-VidalStacey PhanPrachi KhareFeiFei HuChao ZhangPing CaoNeil P. Shah

pharmacologymedicinal chemistryhealth sciencesmedicinedrug discoverydrug resistancehaematopoiesisclinical chemistryhematology

Development of Highly Fluorogenic Styrene Probes for Visualizing Rna in Live Cells. ACS Chemical Biology (2023)

Moon Jung KimYida LiJason A. JungeNathan K. KimScott E. FraserChao Zhang

Identification of Covalent Ligands – From Single Targets to Whole Proteome. Israel Journal of Chemistry (2023)

Chau NgoArunika EkanayakeChao Zhang

proteomicssingle-molecule detectionproteome researchbiochemistrycovalent ligandssingle targetschemistry

Structural and Functional Analyses of a Germline Kras T50I Mutation Provide Insights Into Raf Activation. JCI Insight (2023)

Pan-Yu ChenBenjamin J HuangMax HarrisChristopher BooneWeijie WangHeidi CariasBrian MesionaDaniela MavriciAmanda C KohlerGideon BollagChao ZhangYing ZhangKevin Shannon

structural biologymolecular biologyraf activation

Reactivity-Based Chemical-Genetic Study of Protein Kinases. RSC Medicinal Chemistry (2022)

Renata Rezende MirandaChao Zhang

geneticsmedicinal chemistryreactivity-based chemical-genetic studyprotein kinases

Sars-Cov-2 Couples Evasion of Inflammatory Response to Activated Nucleotide Synthesis. Proceedings of the National Academy of Sciences (2022)

geneticspharmacologysars-cov-2gene expressionvirologyinflammationmedical virologyvirus researchimmunologymedicinal researchmolecular virologyinflammatory responsegeneral virology

Abstract P156: Identification of Previously Unknown Targets for Approved Small-Molecule Drugs Using Chemoproteomic Platform Imtactm. Molecular Cancer Therapeutics (2021)

Vivian ZhangCindy HuangChao ZhangPing Cao

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Similar Faculty Members

John Koomen

Institution

University of South Florida

proteomics

chemical cleavage mechanisms

Philip A. Cole

Institution

Johns Hopkins University

molecular biology

biochemistry

Jens Meiler

Institution

Vanderbilt University

molecular informatics

biomolecular engineering

Harvey R. Herschman

Institution

University of California, Los Angeles

imaging genomics

cell biology

Michael B. Yaffe

Institution

Massachusetts Institute of Technology

immunology

dna damage response

Craig W. Lindsley, Ph.D

Institution

Vanderbilt University

neuroscience

medicine

Shantu Amin

Institution

Pennsylvania State University

cancer letter

polycyclic aromatic hydrocarbon

Owen Witte

Institution

University of California, Los Angeles

immunology

genetics

Said M. Sebti

Institution

Virginia Commonwealth University

receptor tyrosine kinase

molecular cancer

Richard A. Young

Institution

Massachusetts Institute of Technology

oncogene

transcription regulation