Faculty

Institution

Unit

Venue

Ian G. Macara

Professor

Vanderbilt University

Affiliations

Graduate School

Cell and Developmental Biology

School of Medicine

Department of Cell and Developmental Biology

Ian G. Macara is currently serving as a Cell And Developmental Biology Professor at Vanderbilt University.

Honors

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Experiences

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Education

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Ian G. Macara

Vanderbilt University

Professor

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cell biology molecular biology cell signaling biochemistry molecular cell biology signal transduction genetics membrane biology protein science gene expression cellular physiology biological chemistry molecular and cellular biology cellular biochemistry structural biology cellular biology cell regulation cell polarity protein function oncogenes mammalian biology signaling pathways protein structure rna biology cancer biology enzymes molecular physiology protein transport biochemical sciences structural molecular biology developmental cell molecular regulation medicinal research mammary gland redox biology genome biology protein expression nuclear organization cell physiology biomolecular interactions cancer genetics intracellular trafficking nuclear import vascular biology enzyme inhibition gene function membrane transport transcription regulation apoptosis cell migration tissue development receptor (biochemistry) gene regulation biological inorganic chemistry protein secretion protein chemistry biological function hematological malignancies chromosome biology host specificity mutagenesis gtpase-activating protein tunicate blood cells short hairpin rnas par proteins ras superfamily phosphatidylinositol turnover nucleocytoplasmic shuttling mammalian septins conformational switch dendritic spine morphogenesis systems analysis muscarinic receptors epidermal growth factor ras-dependent signalling pathway rna-protein interactions developmental biology stem cell research cancer initiation breast cancer

Notable Scholarly Works

Notable Federal Grants

Collaborators

Non-Canonical Egfr Signaling is Essential for Mapk-Mediated Apical Extrusion of Epithelial Cells. bioRxiv (Cold Spring Harbor Laboratory) (2025)

non-canonical egfr signalingsignaling pathwayscellular physiologycell signalingepithelial cellsreceptor tyrosine kinasesmatrix biologymolecular cell biologycell-matrix interactionsoncogenesmapk-mediated apical extrusiondevelopmental biologysignal transductioncell biology

Actomyosin Contractility is a Potent Suppressor of Mesoderm Induction by Human Pluripotent Stem Cells. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Loic FortWenjun WangIan G Macara

mesoderm inductionstem cellsactomyosin contractilitycell biology

A Size Filter at the Golgi Regulates Apical Membrane Protein Sorting. Nature Cell Biology (2024)

Christian de CaesteckerIan G Macara

apical membrane proteinmembranesmolecular biologymembrane proteinscellular biologymembrane biologycell biology

Scalable Single-Cell Pooled Crispr Screens With Conventional Knockout Vector Libraries. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Mirazul IslamYilin YangAlan J. SimmonsYanwen XuEmilie L. FisherWentao DengBrian C GriebPaola MolinaChristian de CaesteckerMarisol A. Ramirez-SolanoQi LiuWilliam P. TanseyIan G. MacaraJeffrey C. RathmellRobert J. CoffeyKen S. Lau

single-cell analysisbiomolecular engineeringscalable single-cellmolecular biologycrispr screenscomputational biologybiological engineeringcrispr

Temporal Recording of Mammalian Development and Precancer. Nature (2024)

Mirazul IslamYilin YangAlan J. SimmonsVishal M. ShahKrushna Pavan MusaleYanwen XuNaila TasneemZhengyi ChenLinh T. TrinhPaola MolinaMarisol A. Ramirez-SolanoIannish D. SadienJinzhuang DouAndrea RolongKen ChenMark A. MagnusonJeffrey C. RathmellIan G. MacaraDouglas J. WintonQi LiuHamim ZafarReza KalhorGeorge M. ChurchMartha J. ShrubsoleRobert J. CoffeyKen S. Lau

temporal recordingbiologymammalian biologydevelopmental neurobiologydevelopmental biologymammalian development

A Junction-Dependent Mechanism Drives Murine Mammary Cell Intercalation for Ductal Elongation. Developmental Cell (2023)

Alexander PfannensteinIan G. Macara

neurologydermatologyductal elongationstem cell researchdevelopmental celltissue developmentmammalian biologymammary glanddevelopmental neurobiologyjunction-dependent mechanism drivesdevelopmental biologydevelopmental scienceembryonic development

A Size Filter Regulates Apical Protein Sorting. Research Square (Research Square) (2023)

Ian MacaraChristian de Caestecker

technologysize filterbiophysicsnanotechnology

A Junction-Dependent Mechanism Drives Mammary Cell Intercalation for Ductal Elongation. bioRxiv (Cold Spring Harbor Laboratory) (2022)

ductal elongationcellular physiologydevelopmental cellcell growthmorphogenesismolecular cell biologymammary glanddevelopmental biologycellular differentiationcell migrationcell biology

Stem Cell Conversion to the Cardiac Lineage Requires Nucleotide Signalling From Apoptosing Cells. Nature Cell Biology (2022)

Loic FortVivian GamaIan G. Macara

stem cell conversioncardiac lineagestem cellsmolecular biologydevelopmental biologycellular biologycell biology

Abstracts for the Human Genetics Society of Australasia Virtual Conference 24–25 November 2020. Twin research and human genetics (2021)

Fiona LynchBelinda McclarenAmy NisselleClara GaffNicole Van BergenMuktar AhmedFelicity CollinsMark CowleyAnnalisa VetroRussell DaleDaniella HockChristian De CaesteckerMinal MenezesSean MasseyGladys HoTiziana PisanoSeana GloverJovanka GusmanDavid StroudMarcel DingerRenzo GuerriniIan MacaraJohn ChristodoulouJane TillerLouise KeoghAideen Mcinerney-LeoAndrea BelcherKristine Barlow-StewartTiffany BoughtwoodMartin DelatyckiIngrid WinshipMargaret OtlowskiPaul LacazeDaniz KooshavarKate RineyChristopher BarnettJonathon SilbersteinRani SachdevShekeeb MohammadKathryn NorthMichael FaheyIngrid SchefferNicholas SmithTyson WarePaul LockhartRichard LeventerSimranpreet KaurAlejandro Hidalgo-GonzalezHolly VogesKristen VerheyCameron NowellBreane BudaitisYang YueCarolyn EllawayNicola Brunetti-PierriGerarda CappuccioIrene BrunoLia BoyleVincenzo NigroAnnalaura TorellaTony RoscioliMatthew BurtonBitten Schonewolf-GreulichZeynep TümerZornitza StarkNatasha BrownDi MilnesJason PinnerMichael KruerSomayeh BakhtiariBertrand IsidorFrédéric BilanWendy ChungWendy GoldSamantha EdwardsRoyston OngGeorgina HollingsworthKaren HarropSarah MooreBenjamin KamienNicholas PachterMark DavisKaren CarpenterJohn BeilbyNigel LaingRachael JefferyJennifer ThompsonTerri MclarenTina LameyJohn De RoachFred ChenRebecca FoulgerEleanor WilliamsBryony ThompsonChirag PatelIvone LeongLouise DaughertySarah LeighArina PuzriakovaCatherine Snow

genomicshuman geneticsgenetics

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Ian G. Macara

Professor

Vanderbilt University

Affiliations

Graduate School

Cell and Developmental Biology

School of Medicine

Department of Cell and Developmental Biology

Ian G. Macara is currently serving as a Cell And Developmental Biology Professor at Vanderbilt University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ian G. Macara

Vanderbilt University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Non-Canonical Egfr Signaling is Essential for Mapk-Mediated Apical Extrusion of Epithelial Cells. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Actomyosin Contractility is a Potent Suppressor of Mesoderm Induction by Human Pluripotent Stem Cells. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Loic FortWenjun WangIan G Macara

mesoderm inductionstem cellsactomyosin contractilitycell biology

A Size Filter at the Golgi Regulates Apical Membrane Protein Sorting. Nature Cell Biology (2024)

Christian de CaesteckerIan G Macara

apical membrane proteinmembranesmolecular biologymembrane proteinscellular biologymembrane biologycell biology

Scalable Single-Cell Pooled Crispr Screens With Conventional Knockout Vector Libraries. bioRxiv (Cold Spring Harbor Laboratory) (2024)

single-cell analysisbiomolecular engineeringscalable single-cellmolecular biologycrispr screenscomputational biologybiological engineeringcrispr

Temporal Recording of Mammalian Development and Precancer. Nature (2024)

temporal recordingbiologymammalian biologydevelopmental neurobiologydevelopmental biologymammalian development

A Junction-Dependent Mechanism Drives Murine Mammary Cell Intercalation for Ductal Elongation. Developmental Cell (2023)

Alexander PfannensteinIan G. Macara

A Size Filter Regulates Apical Protein Sorting. Research Square (Research Square) (2023)

Ian MacaraChristian de Caestecker

technologysize filterbiophysicsnanotechnology

A Junction-Dependent Mechanism Drives Mammary Cell Intercalation for Ductal Elongation. bioRxiv (Cold Spring Harbor Laboratory) (2022)

ductal elongationcellular physiologydevelopmental cellcell growthmorphogenesismolecular cell biologymammary glanddevelopmental biologycellular differentiationcell migrationcell biology

Stem Cell Conversion to the Cardiac Lineage Requires Nucleotide Signalling From Apoptosing Cells. Nature Cell Biology (2022)

Loic FortVivian GamaIan G. Macara

stem cell conversioncardiac lineagestem cellsmolecular biologydevelopmental biologycellular biologycell biology

Abstracts for the Human Genetics Society of Australasia Virtual Conference 24–25 November 2020. Twin research and human genetics (2021)

genomicshuman geneticsgenetics

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Similar Faculty Members

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cell cycle

cell cycle control

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gastrointestinal oncology

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Michael B. Yaffe

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Massachusetts Institute of Technology

immunology

dna damage response

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gi neoplasia

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