Faculty

Institution

Unit

Venue

Jieqing Zhu

Investigator Versiti Blood Research Institute; Professor

Medical College of Wisconsin

Affiliations

Biochemistry

Jieqing Zhu is currently serving as a Biochemistry Investigator Versiti Blood Research Institute; Professor at Medical College of Wisconsin.

Honors

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Experiences

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Education

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Jieqing Zhu

Medical College of Wisconsin

Investigator Versiti Blood Research Institute; Professor

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molecular biology immunology cell biology hematology biochemistry blood platelet structural biology cell signaling membrane biology immune responses integrin activation biological chemistry thrombosis vascular biology molecular cell biology virus research molecular and cellular biology medicinal chemistry structural molecular biology cellular biology virus-host interactions cell surface cell and molecular biology cellular physiology protein science redox biology biomolecular structure cell adhesion immunoglobulin e platelet antagonist signaling pathways blood cells viral pathogenesis ligand binding von willebrand factor structure-guided design structural basis cell research laboratory medicine medicinal research free radical biology transition metal chemistry peptides cell biomechanics translational physiology pharmaceutical sciences translational pharmacology arterial disease integrative biology glycosylation protein chemistry stabilization (medicine) cellular immune responses cell interactions cell regulation intracellular trafficking lipid science phagocytes coagulopathy membrane transport molecular biological method molecular microbiology pharmaceutical chemistry host-microbe interactions redox signaling biomolecular interactions structure relationships structural evidence transmembrane domains integrin outside-in signaling high-affinity platelet intracranial bleeding deadbolt models conformational regulation closure-stabilizing integrin inhibitors general chemical principle

Notable Scholarly Works

Notable Federal Grants

Collaborators

Borrelia Burgdorferi Tolerates Alteration to P66 Porin Function in a Murine Infectivity Model. Frontiers in Cellular and Infection Microbiology (2025)

Christa H. FierrosMarie-Line FaucillionBeth L. HahnPhillip AndersonMari BondeJulie R. KesslerMatthew C. SurdelKyler S. CrawfordYan GaoJieqing ZhuSven BergströmJenifer Coburn

microbial diseaseinfectious diseasespathogenic bacteriamurine infectivity modelmicrobiologypathogensmicrobial pathogenesis

Luminescent Sensing of Conformational Integrin Activation in Living Cells. Cell Reports (2025)

Giulia VillariNoemi GioelliMarta GinoHeng ZhangKelly HodgeFrancesca CorderoSara ZanivanJieqing ZhuGuido Serini

luminescent sensingconformational integrin activationcell biologycellular biologyliving cells

Oxidized Ldl Stimulates Pkm2-Mediated Mtros Production and Phagocytosis. Journal of Lipid Research (2025)

Jue ZhangJackie ChangVaya ChenMirza Ahmar BegWenxin HuangLance VickYaxin WangHeng ZhangErin YttreAnkan GuptaMark CastleberryZiyu ZhangWen DaiJieqing ZhuShan SongMoua YangAshley Kaye BrownZhen XuYan-Qing MaBrian C SmithJacek ZielonkaJames G TraylorCyrine Ben DhaouA Wayne OrrWeiguo CuiYiliang Chen

lipidsbiochemistrylipid scienceoxidative stressphagocytesredox biology

The Pivotal Role of Von Willebrand Factor Binding to Platelet αIibβ3 in Stabilizing the Formation of a Platelet Plug at Sites of Injury. Haematologica (2025)

Qizhen ShiJeremy G MattsonPatricia A MorateckPamela A ChristophersonJocelyn A SchroederScot A FahsJessica RaptenMarie L SchulteHartmut WeilerJieqing ZhuSandra L HaberichterVeronica H FloodRobert R Montgomery

von willebrand factorimmunologyhematologyblood plateletplatelet plug

Facilitating and Restraining Virus Infection Using Cell-Attachable Soluble Viral Receptors. Proceedings of the National Academy of Sciences (2024)

Heng ZhangZhengli WangHuong T. T. NguyenMarjorie Cornejo PontelliWanrong QiLiem RaoZhuoming LiuSean P. J. WhelanJieqing Zhu

systems biologyvirus infectionvirologyvirus research

Prothrombotic Antibodies Targeting the Spike Protein's Receptor-Binding Domain in Severe Covid-19. Blood (2024)

Wen ZhuYongwei ZhengMei YuNathan WitmanLu ZhouJianhui WeiYongguang ZhangPaytsar TopchyanChristine NguyenRae JaneckeAnand PadmanabhanLisa Baumann KreuzigerGilbert C WhiteParameswaran HariTongjun GuAlexander Thompson FieldsLucy KornblithRichard H AsterJieqing ZhuWeiguo CuiShawn M JobeMary Beth GrahamDemin WangDavid WangRenren Wen

viral pathogenesisinfectious diseasesimmunologyprothrombotic antibodiesreceptor-binding domaincovid-19spike proteinvirus research

A Single F153Sβ3 Mutation Causes Constitutive Integrin αIibβ3 Activation in a Variant Form of Glanzmann Thrombasthenia. Blood Advances (2023)

Sevasti B. KoukouritakiAye Myat M. ThinnKatrina J. AshworthJuan FangHaley S. SlaterLily M. DuHuong Thi Thu NguyenXavier PilloisAlan T. NurdenChristopher J. NgJorge Di PaolaJieqing ZhuDavid A. Wilcox

thrombosishematologyblood plateletglanzmann thrombastheniagenetics

Family-Wide Analysis of Integrin Structures Predicted by Alphafold2. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Heng ZhangDaniel S. ZhuJieqing Zhu

family-wide analysismolecular biologyintegrin structures

Integrin α 5 β 1 Contributes to Cell Fusion and Inflammation Mediated by Sars-Cov-2 Spike via Rgd-Independent Interaction. Proceedings of the National Academy of Sciences (2023)

Heng ZhangZhengli WangHuong T. T. NguyenAbigail J. WatsonQifang LaoAn LiJieqing Zhu

rgd-independent interactioninflammationinfectious diseasesvirologyimmunologysars-cov-2virus research

Intracellular Tpa–Pai-1 Interaction Determines Vldl Assembly in Hepatocytes. Science (2023)

Wen DaiHeng ZhangHayley LundZiyu ZhangMark CastleberryMaya RodriguezGeorge KuriakoseSweta GuptaMagdalena LewandowskaHayley R. PowersSwati ValmikiJieqing ZhuAmy D. ShapiroM. Mahmood HussainJosé A. LópezMary G. Sorci-ThomasRoy L. SilversteinHenry N. GinsbergDaisy SahooIra TabasZe Zheng

tumor biologycell interactionsimmunologycell biologycellular physiologydermatologycellular immune responsestissue (biology)

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Jieqing Zhu

Investigator Versiti Blood Research Institute; Professor

Medical College of Wisconsin

Affiliations

Biochemistry

Jieqing Zhu is currently serving as a Biochemistry Investigator Versiti Blood Research Institute; Professor at Medical College of Wisconsin.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jieqing Zhu

Medical College of Wisconsin

Investigator Versiti Blood Research Institute; Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Borrelia Burgdorferi Tolerates Alteration to P66 Porin Function in a Murine Infectivity Model. Frontiers in Cellular and Infection Microbiology (2025)

Christa H. FierrosMarie-Line FaucillionBeth L. HahnPhillip AndersonMari BondeJulie R. KesslerMatthew C. SurdelKyler S. CrawfordYan GaoJieqing ZhuSven BergströmJenifer Coburn

microbial diseaseinfectious diseasespathogenic bacteriamurine infectivity modelmicrobiologypathogensmicrobial pathogenesis

Luminescent Sensing of Conformational Integrin Activation in Living Cells. Cell Reports (2025)

Giulia VillariNoemi GioelliMarta GinoHeng ZhangKelly HodgeFrancesca CorderoSara ZanivanJieqing ZhuGuido Serini

luminescent sensingconformational integrin activationcell biologycellular biologyliving cells

Oxidized Ldl Stimulates Pkm2-Mediated Mtros Production and Phagocytosis. Journal of Lipid Research (2025)

lipidsbiochemistrylipid scienceoxidative stressphagocytesredox biology

The Pivotal Role of Von Willebrand Factor Binding to Platelet αIibβ3 in Stabilizing the Formation of a Platelet Plug at Sites of Injury. Haematologica (2025)

von willebrand factorimmunologyhematologyblood plateletplatelet plug

Facilitating and Restraining Virus Infection Using Cell-Attachable Soluble Viral Receptors. Proceedings of the National Academy of Sciences (2024)

Heng ZhangZhengli WangHuong T. T. NguyenMarjorie Cornejo PontelliWanrong QiLiem RaoZhuoming LiuSean P. J. WhelanJieqing Zhu

systems biologyvirus infectionvirologyvirus research

Prothrombotic Antibodies Targeting the Spike Protein's Receptor-Binding Domain in Severe Covid-19. Blood (2024)

viral pathogenesisinfectious diseasesimmunologyprothrombotic antibodiesreceptor-binding domaincovid-19spike proteinvirus research

A Single F153Sβ3 Mutation Causes Constitutive Integrin αIibβ3 Activation in a Variant Form of Glanzmann Thrombasthenia. Blood Advances (2023)

Sevasti B. KoukouritakiAye Myat M. ThinnKatrina J. AshworthJuan FangHaley S. SlaterLily M. DuHuong Thi Thu NguyenXavier PilloisAlan T. NurdenChristopher J. NgJorge Di PaolaJieqing ZhuDavid A. Wilcox

thrombosishematologyblood plateletglanzmann thrombastheniagenetics

Family-Wide Analysis of Integrin Structures Predicted by Alphafold2. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Heng ZhangDaniel S. ZhuJieqing Zhu

family-wide analysismolecular biologyintegrin structures

Integrin α 5 β 1 Contributes to Cell Fusion and Inflammation Mediated by Sars-Cov-2 Spike via Rgd-Independent Interaction. Proceedings of the National Academy of Sciences (2023)

Heng ZhangZhengli WangHuong T. T. NguyenAbigail J. WatsonQifang LaoAn LiJieqing Zhu

rgd-independent interactioninflammationinfectious diseasesvirologyimmunologysars-cov-2virus research

Intracellular Tpa–Pai-1 Interaction Determines Vldl Assembly in Hepatocytes. Science (2023)

tumor biologycell interactionsimmunologycell biologycellular physiologydermatologycellular immune responsestissue (biology)

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Leslie V. Parise

Institution

University of North Carolina at Chapel Hill

health science

cardiovascular disease

Simone Sidoli

Institution

Albert Einstein College of Medicine

protein mass spectrometry

proteome research

Jun Qin

Institution

Case Western Reserve University

cell-matrix interaction

protein structure

Yoshikazu Takada

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extracellular matrix

matrix biology

Suzanne Pfeffer

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Stanford University

neurovirology

infectious diseases

Lawrence Shapiro

Institution

Columbia University

developmental biology

cell adhesion

Parastoo Azadi

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polysaccharide

glycosylation

Ganes C. Sen

Institution

Case Western Reserve University

viral oncology

viral pathogenesis

Peter Walter

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molecular biology

cell biology

Peter Edwards

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membrane biology

biochemistry