Faculty

Institution

Unit

Venue

Peter Edwards

Distinguished Research Professor Biological Chemistry; Distinguished Research Professor Medicine

University of California, Los Angeles

Affiliations

David Geffen School of Medicine

Biological Chemistry

Peter Edwards is currently serving as a Biological Chemistry Distinguished Research Professor Biological Chemistry; Distinguished Research Professor Medicine at University of California, Los Angeles.

Honors

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Experiences

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Education

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Peter Edwards

University of California, Los Angeles

Distinguished Research Professor Biological Chemistry; Distinguished Research Professor Medicine

You can click a keyword to filter the displayed items

membrane biology biochemistry molecular biology liver physiology pharmacology biological chemistry genetics enzymes gene expression vascular biology protein science clinical lipidology hepatology lipids hematology molecular physiology redox biology lipid science endocrinology mammalian biology atherosclerosis biochemical sciences lipoprotein metabolism cardiovascular research medicinal research gene function cell metabolism molecular regulation gene regulation transcription regulation protein expression protein transport lipid chemistry enzyme inhibition lipid analysis thrombosis cellular physiology metabolic regulation protein chemistry angiology cellular biochemistry membrane transport protein synthesis lipid disorders receptor (biochemistry) hyperlipidemia steroid metabolism renal function biocatalysis functional modification rna biology human monocyte-macrophages functional regulation dyslipidemia host response host specificity mutagenesis biological inorganic chemistry biochemical genetics cell regulation cholesterol efflux bile acids rat liver isolated rat hepatocytes farnesoid x-activated receptor cholesterol metabolism signaling pathways cholesterol biosynthetic pathway circadian rhythm rat hepatocytes enzyme activity reductase activity nuclear receptor fxr cellular cholesterol efflux nuclear receptors lipid homeostasis

Notable Scholarly Works

Notable Federal Grants

Collaborators

Fxr Activation Protects Against Nafld via Bile-Acid-Dependent Reductions in Lipid Absorption. Cell Metabolism (2021)

Bethan L. CliffordLeslie R. SedgemanKevin J. WilliamsPauline MorandAngela ChengKelsey E. JarrettAlvin P. ChanMadelaine C. Brearley-SholtoAnnika WahlströmJulianne W. AshbyWilliam BarshopJames WohlschlegelAnna C. CalkinYingying LiuAnders ThorellPeter J. MeikleBrian G. DrewJulia J. MackHanns-Ulrich MarschallElizabeth J. TarlingPeter A. EdwardsThomas Q. de Aguiar Vallim

lipid absorptioninflammationvascular biologyclinical lipidologytumor biologyliver physiologyphysiologybile-acid-dependent reductionshepatologyhematologycell metabolismmembrane biologypharmacologyhealth sciences

Transcription Factor Maff (Maf Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism. Circulation (2021)

Moritz von ScheidtYuqi ZhaoThomas Q. de Aguiar VallimNam CheMichael WiererMarcus M. SeldinOscar FranzénZeyneb KurtShichao PangDario BongiovanniMasayuki YamamotoPeter A. EdwardsArno RuusaleppJason C. KovacicMatthias MannJohan L.M. BjörkegrenAldons J. LusisXia YangHeribert Schunkert

inflammationcardiologytranscription factorsatherosclerosistranscription factor maffmembrane biologycholesterol metabolismhealth sciences

A Mafg-Lncrna Axis Links Systemic Nutrient Abundance to Hepatic Glucose Metabolism. Nature Communications (2020)

Marta Pradas-JuniNils R. HansmeierJenny C. LinkElena SchmidtBjørk Ditlev LarsenPaul KlemmNicola MeolaHande TopelRute LoureiroInes DhaouadiChristoph A. KieferRobin SchwarzerSajjad KhaniMatteo OliverioMotoharu AwazawaPeter FrommoltJoerg HeerenLudger SchejaMarkus HeineChristoph DieterichHildegard BüningLing YangHaiming CaoDario F. De JesusRohit N. KulkarniBranko ZevnikSimon E. TröderUwe KnippschildPeter A. EdwardsRichard G. LeeMasayuki YamamotoIgor UlitskyEduardo Fernandez-RebolloThomas Q. de Aguiar VallimJan-Wilhelm Kornfeld

liver physiologygeneticstumor biologynaturenutrient physiologylipid sciencemolecular biologyhepatic glucose metabolismrenal functioncellular physiologysystems biologyendocrinologyrna biologymetabolismmolecular metabolismhepatologymolecular physiologymembrane biologymitochondrial function

P1844The Transcription Factor Maff Regulates an Atherosclerosis Relevant Gene Network. European Heart Journal (2018)

M Von ScheidtY ZhaoT Q De Aguiar VallimN CheO FranzenZ KurtM YamamotoP A EdwardsA RuusaleppJ KovacicJ L M BjorkegrenA J LusisX YangH Schunkert

immunologytranscription factorsatherosclerosismolecular biologygene regulatory networksgenetics

Intracellular Localization of Endogenous Mouse Abcg1 is Mimicked by Both Abcg1-L550 and Abcg1-P550—Brief Report. Arteriosclerosis Thrombosis and Vascular Biology (2016)

Elizabeth J. TarlingPeter A. Edwards

vascular biologycardiologyangiologyphysiologycell biologythrombosishematologyatherosclerosismembrane biologymolecular biologymammalian biologyintracellular localization

Mafg is a Transcriptional Repressor of Bile Acid Synthesis and Metabolism. Cell Metabolism (2016)

Thomas Q. de Aguiar VallimElizabeth J. TarlingHannah AhnLee R. HageyCasey E. RomanoskiRichard G. LeeMark J. GrahamHozumi MotohashiMasayuki YamamotoPeter A. Edwards

metabolismtumor biologyliver physiologyphysiologyhepatologycell metabolismgene regulationmolecular physiologymembrane biologygene functiontranscription regulationmolecular biologypharmacologytranscriptional repressorendocrinologyrna biologybile acid synthesis

Abstract 49: The Transcriptional Repressor Mafg Regulates Cholesterol Catabolism. Arteriosclerosis Thrombosis and Vascular Biology (2015)

Thomas Q de Aguiar VallimElizabeth J TarlingHannah AhnLee R HageyCasey E RomanoskiRichard G LeeMark J GrahamHozumi MotohashiMasayuki YamamotoPeter A Edwards

liver physiologypharmacologygeneticsvascular biologyatherosclerosishematologytranscription regulationmolecular biologycardiologyangiologythrombosiscellular physiologygene regulationhepatologytranscriptional repressor mafgmolecular physiologymembrane biologygene functioncancer genetics

Abstract 21: Loss of Abcg1 Drives the Site-Selective Expansion of B-1 B Cells and Secretion of Atheroprotective Natural Antibodies, in Response to Local Accumulation of Specific Oxidized Lipids. Arteriosclerosis Thrombosis and Vascular Biology (2013)

Elizabeth J TarlingAyelet GonenXuchu QueCody DiehlJoseph L WitztumAngel BaldanPeter A Edwards

protein secretionimmunologydermatologytransplant arteriopathyvascular biologyclinical lipidologynephrologycirculatory physiologyvascular diseasecell biologyatheroprotective natural antibodiesatherosclerosishematologysite-selective expansionarterial diseasespecific oxidized lipidscardiologyangiologythrombosiscardiovascular researchhepatologylocal accumulation

Abstract 76: Microrna-144 Regulates Hepatic Abca1 and Plasma Hdl Following Activation of the Nuclear Receptor Fxr. Arteriosclerosis Thrombosis and Vascular Biology (2013)

Thomas VallimElizabeth TarlingTammy KimMete CivelekAngel BaldanChristine EsauPeter A Edwards

lipidsplasma hdl cholesterolpathologymetabolismliver physiologynuclear receptor fxrlipoprotein metabolismcell biologyatherosclerosiscell metabolismmicrorna detectionmolecular physiologyhdl- cholesterolgene expressionlipid synthesis

Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration. Cell Metabolism (2013)

Abdoulaye SeneAslam A. KhanDouglas CoxRei E.I. NakamuraAndrea SantefordBryan M. KimRohini SidhuMichael D. OnkenJ. William HarbourShira Hagbi-LeviItay ChowersPeter A. EdwardsAngel BaldanJohn S. ParksDaniel S. OryRajendra S. Apte

cardiovascular diseasevascular biologymetabolismcardiovascular researchliver physiologyimmunologyhost responseageingdermatologycell metabolismocular diseaseocular pathologyaging-associated diseasescholesterol effluxage-related macular degenerationophthalmologyhost specificitysenescent macrophages

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Peter Edwards

Distinguished Research Professor Biological Chemistry; Distinguished Research Professor Medicine

University of California, Los Angeles

Affiliations

David Geffen School of Medicine

Biological Chemistry

Peter Edwards is currently serving as a Biological Chemistry Distinguished Research Professor Biological Chemistry; Distinguished Research Professor Medicine at University of California, Los Angeles.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Peter Edwards

University of California, Los Angeles

Distinguished Research Professor Biological Chemistry; Distinguished Research Professor Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Fxr Activation Protects Against Nafld via Bile-Acid-Dependent Reductions in Lipid Absorption. Cell Metabolism (2021)

Transcription Factor Maff (Maf Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism. Circulation (2021)

inflammationcardiologytranscription factorsatherosclerosistranscription factor maffmembrane biologycholesterol metabolismhealth sciences

A Mafg-Lncrna Axis Links Systemic Nutrient Abundance to Hepatic Glucose Metabolism. Nature Communications (2020)

P1844The Transcription Factor Maff Regulates an Atherosclerosis Relevant Gene Network. European Heart Journal (2018)

M Von ScheidtY ZhaoT Q De Aguiar VallimN CheO FranzenZ KurtM YamamotoP A EdwardsA RuusaleppJ KovacicJ L M BjorkegrenA J LusisX YangH Schunkert

immunologytranscription factorsatherosclerosismolecular biologygene regulatory networksgenetics

Intracellular Localization of Endogenous Mouse Abcg1 is Mimicked by Both Abcg1-L550 and Abcg1-P550—Brief Report. Arteriosclerosis Thrombosis and Vascular Biology (2016)

Elizabeth J. TarlingPeter A. Edwards

vascular biologycardiologyangiologyphysiologycell biologythrombosishematologyatherosclerosismembrane biologymolecular biologymammalian biologyintracellular localization

Mafg is a Transcriptional Repressor of Bile Acid Synthesis and Metabolism. Cell Metabolism (2016)

Thomas Q. de Aguiar VallimElizabeth J. TarlingHannah AhnLee R. HageyCasey E. RomanoskiRichard G. LeeMark J. GrahamHozumi MotohashiMasayuki YamamotoPeter A. Edwards

Abstract 49: The Transcriptional Repressor Mafg Regulates Cholesterol Catabolism. Arteriosclerosis Thrombosis and Vascular Biology (2015)

Thomas Q de Aguiar VallimElizabeth J TarlingHannah AhnLee R HageyCasey E RomanoskiRichard G LeeMark J GrahamHozumi MotohashiMasayuki YamamotoPeter A Edwards

Elizabeth J TarlingAyelet GonenXuchu QueCody DiehlJoseph L WitztumAngel BaldanPeter A Edwards

Abstract 76: Microrna-144 Regulates Hepatic Abca1 and Plasma Hdl Following Activation of the Nuclear Receptor Fxr. Arteriosclerosis Thrombosis and Vascular Biology (2013)

Thomas VallimElizabeth TarlingTammy KimMete CivelekAngel BaldanChristine EsauPeter A Edwards

Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration. Cell Metabolism (2013)

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