Faculty

Institution

Unit

Venue

Jamie Arnold

Research Associate Professor

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Cell Biology and Physiology

Microbiology and Immunology

Jamie Arnold is currently serving as a Cell Biology And Physiology Research Associate Professor at University of North Carolina At Chapel Hill.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jamie Arnold

University of North Carolina at Chapel Hill

Research Associate Professor

You can click a keyword to filter the displayed items

molecular biology virology virus research genetics biochemistry viral genetics rna biology molecular virology immunology structural biology gene expression general virology enzymes genome biology viral replication virus-host interactions protein science molecular genetics biological chemistry medicinal research viral evolution rna-dependent rna polymerase structural molecular biology nucleic acids mitochondrial function viral structural protein transcription (biology) membrane biology enzyme inhibition microbial pathogenesis medical virology viral pathogenesis virus structure transcription regulation plo biology avian biology molecular cell biology antiviral research organic electronics protein purification protein expression gene regulation viral diagnostics biochemical sciences cell research biochemical genetics cellular biology fragmentation effect virus transmission arbovirus rna-dependent rna polymerases structure-function relationships nucleotidyl transfer rna virus single-cell virology high-throughput magnetic tweezers viral attenuation rna viruses surface chemistry surface nanotechnology surface modification viral hepatitis supramolecular assemblies molecular self-assembly antiviral therapy mutagenesis cell manipulation genetic technologies transcriptomics technology quasispecies diversity viral population cooperative interactions rna virus mutagen organic molecules electron transfer conjugated organic oligomers nucleic acid chemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Post-Assembly Conformational Change Makes the Sars-Cov-2 Polymerase Elongation-Competent. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Misha KleinArnab DasSubhas C. BeraThomas K. AndersonDana KocincovaHery W. LeeBing WangFlavia S. PapiniJohn C. MareckiJamie J. ArnoldCraig E. CameronKevin D. RaneyIrina ArtsimovitchMathias GötteRobert N. KirchdoerferMartin DepkenDavid Dulin

sars-cov-2molecular biologyprotein structurepost-assembly conformational changeviral structural proteinvirus research

Discovery of a Cell-Active Chikungunya Virus Nsp2 Protease Inhibitor Using a Covalent Fragment-Based Screening Approach. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Eric M. MertenJohn D. SearsTina M. LeisnerPaul B. HardyAnirban GhoshalMohammad Anwar HossainKesatebrhan Haile AsressuPeter J. BrownMichael A. StashkoLaura HerringAngie L. MordantThomas S. WebbChristine A. MillsNatalie K. BarkerZachary J. StreblowSumera PerveenCheryl ArrowsmithJamie J. ArnoldCraig E CameronDaniel N. StreblowNathaniel J. MoormanMark HeiseTimothy M. WillsonKonstantin PopovKenneth H. Pearce

clinical microbiologyviral diagnosticsvirologylaboratory investigationmicrobiologyglobal healthmolecular diagnosticsmolecular biologydrug discoveryvirus research

Identification of a Cell-Active Chikungunya Virus Nsp2 Protease Inhibitor Using a Covalent Fragment-Based Screening Approach. Proceedings of the National Academy of Sciences (2024)

Eric M. MertenJohn D. SearsTina M. LeisnerP. Brian HardyAnirban GhoshalMohammad Anwar HossainKesatebrhan Haile AsressuPeter J. BrownEdwin G. TseMichael A. StashkoKelin LiJacqueline L. Norris-DrouinLaura E. HerringAngie L. MordantThomas S. WebbChristine A. MillsNatalie K. BarkerZachary J. StreblowSumera PerveenCheryl H. ArrowsmithRafael Miguez CouñagoJamie J. ArnoldCraig E. CameronDaniel N. StreblowNathaniel J. MoormanMark T. HeiseTimothy M. WillsonKonstantin I. PopovKenneth H. Pearce

antiviral drug developmentvirologybiochemistrymicrobiologyantiviral researchmolecular diagnosticsmolecular biologymolecular virologyprotein structureviral diagnosticsenzyme inhibitionvirus research

Single-Cell Virology: On-Chip, Quantitative Characterization of the Dynamics of Virus Spread From One Single Cell to Another. Viruses (2024)

Wu LiuClaus O. WilkeJamie J. ArnoldMohamad S. SotoudeganCraig E. Cameron

single-cell virologyvirologyvirus transmissionquantitative characterizationvirus research

Maintenance of a Host-Specific Minority Mutation in the West Nile Virus Ns3. iScience (2023)

Haley S. CaldwellLili KuoJanice D. PataAlan P. DupuisJamie J. ArnoldCalvin YeagerJessica StoutCheri A. KoetznerAnne F. PayneSean M. BialosukniaElyse M. BankerTaylor A. NolenCraig E. CameronAlexander T. Ciota

cytogeneticsviral geneticsvirologyhost geneticsviral evolutionpopulation geneticsgeneticshost-specific minority mutation

Mechanism of Assembly of an Elongation-Competent Sars-Cov-2 Replication Transcription Complex. Biophysical Journal (2023)

Misha KleinSubhas C. BeraThomas K. AndersonBing WangFlavia S. PapiniJamie J. ArnoldCraig E. CameronMartin DepkenRobert N. KirchdoerferIrina ArtsimovitchDavid Dulin

biophysicsgeneral virologyviral geneticsvirologysequence assemblyviral replicationgenome biologysars-cov-2molecular biophysicsmolecular biologyviral evolutionreplicationgene expressionprotein assemblygeneticsvirus research

Structural and Functional Characterization of Enteroviral 2C Protein, an Rna-Stimulated Atpase. Acta Crystallographica Section A Foundations and Advances (2023)

Neela YennawarCalvin YeagerGriffin CarterDavid GoharaEric EnemarkJamie ArnoldCraig Cameron

crystal structuresmolecular structurerna-stimulated atpasestructural molecular biologyprotein x-ray crystallographyenzymesx-ray crystallographymolecular biologyviral structural proteinvirologybiochemistryprotein structurestructural biologyvirus researchbiophysicsprotein sciencestructural chemistrycrystallographyvirus structurefunctional characterization

The Enterovirus Genome Can Be Translated in an Ires-Independent Manner That Requires the Initiation Factors Eif2A/Eif2d. PLoS Biology (2023)

Hyejeong KimDavid Aponte-DiazMohamad S. SotoudeganDjoshkun ShengjulerJamie J. ArnoldCraig E. Cameron

plo biologyvirologyinitiation factorstranscription (biology)molecular biologyenterovirus genomegene expressionires-independent mannergenetics

Contributors. Elsevier eBooks (2022)

Ron AltermanJeffrey E. ArleKerry BradleySergio CanaveroSteven M. FalowskiChad W. FarleyYakov GologorskyJianwen Wendy GuH. Louis JournéeJohn KastOlga KhazenJoachim K. KraussVignessh KumarMark LentRobert M. LevyAndres M. LozanoCharles MackelGeorge T. MandyburBryan L. McLaughlinDaniel R. MerrillAlon Y. MogilnerGabi MolnarGuillermo A. MonsalveRichard B. NorthYunseo Linda ParkJohn ParkerShrey PatelJulie G. PilitsisFrancisco A. PonceJason E. PopeAdolfo Ramirez-ZamoraLouis J. RasoJoshua M. RosenowJay L. ShilsPeter SingleKonstantin V. SlavinMichael D. StaudtMark M. SteckerHuy Q. Truong

Enteroviral 2C Protein is an Rna-Stimulated Atpase and Uses a Two-Step Mechanism for Binding to Rna and Atp. Nucleic Acids Research (2022)

Calvin YeagerGriffin CarterDavid W GoharaNeela H YennawarEric J EnemarkJamie J ArnoldCraig E Cameron

enzymesvirologyvirus-host interactionsprotein sciencetwo-step mechanismnucleic acidsbiochemistryrna-stimulated atpasemolecular biologymolecular virologygene expressionenzyme inhibitionrna biologygenetics

1
2
3
4
5
11
10 / page

Jamie Arnold

Research Associate Professor

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Cell Biology and Physiology

Microbiology and Immunology

Jamie Arnold is currently serving as a Cell Biology And Physiology Research Associate Professor at University of North Carolina At Chapel Hill.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jamie Arnold

University of North Carolina at Chapel Hill

Research Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Post-Assembly Conformational Change Makes the Sars-Cov-2 Polymerase Elongation-Competent. bioRxiv (Cold Spring Harbor Laboratory) (2025)

sars-cov-2molecular biologyprotein structurepost-assembly conformational changeviral structural proteinvirus research

Discovery of a Cell-Active Chikungunya Virus Nsp2 Protease Inhibitor Using a Covalent Fragment-Based Screening Approach. bioRxiv (Cold Spring Harbor Laboratory) (2024)

clinical microbiologyviral diagnosticsvirologylaboratory investigationmicrobiologyglobal healthmolecular diagnosticsmolecular biologydrug discoveryvirus research

Identification of a Cell-Active Chikungunya Virus Nsp2 Protease Inhibitor Using a Covalent Fragment-Based Screening Approach. Proceedings of the National Academy of Sciences (2024)

antiviral drug developmentvirologybiochemistrymicrobiologyantiviral researchmolecular diagnosticsmolecular biologymolecular virologyprotein structureviral diagnosticsenzyme inhibitionvirus research

Single-Cell Virology: On-Chip, Quantitative Characterization of the Dynamics of Virus Spread From One Single Cell to Another. Viruses (2024)

Wu LiuClaus O. WilkeJamie J. ArnoldMohamad S. SotoudeganCraig E. Cameron

single-cell virologyvirologyvirus transmissionquantitative characterizationvirus research

Maintenance of a Host-Specific Minority Mutation in the West Nile Virus Ns3. iScience (2023)

cytogeneticsviral geneticsvirologyhost geneticsviral evolutionpopulation geneticsgeneticshost-specific minority mutation

Mechanism of Assembly of an Elongation-Competent Sars-Cov-2 Replication Transcription Complex. Biophysical Journal (2023)

Misha KleinSubhas C. BeraThomas K. AndersonBing WangFlavia S. PapiniJamie J. ArnoldCraig E. CameronMartin DepkenRobert N. KirchdoerferIrina ArtsimovitchDavid Dulin

Structural and Functional Characterization of Enteroviral 2C Protein, an Rna-Stimulated Atpase. Acta Crystallographica Section A Foundations and Advances (2023)

Neela YennawarCalvin YeagerGriffin CarterDavid GoharaEric EnemarkJamie ArnoldCraig Cameron

The Enterovirus Genome Can Be Translated in an Ires-Independent Manner That Requires the Initiation Factors Eif2A/Eif2d. PLoS Biology (2023)

Hyejeong KimDavid Aponte-DiazMohamad S. SotoudeganDjoshkun ShengjulerJamie J. ArnoldCraig E. Cameron

plo biologyvirologyinitiation factorstranscription (biology)molecular biologyenterovirus genomegene expressionires-independent mannergenetics

Contributors. Elsevier eBooks (2022)

Enteroviral 2C Protein is an Rna-Stimulated Atpase and Uses a Two-Step Mechanism for Binding to Rna and Atp. Nucleic Acids Research (2022)

Calvin YeagerGriffin CarterDavid W GoharaNeela H YennawarEric J EnemarkJamie J ArnoldCraig E Cameron

1
2
3
4
5
11
10 / page

Similar Faculty Members

Craig E. Cameron

Institution

University of North Carolina at Chapel Hill

antiviral therapy

virus research

Robert H. Silverman

Institution

Case Western Reserve University

innate immune system

viral infections

Ronald Swanstrom

Institution

University of North Carolina at Chapel Hill

virology

general virology

Jack Griffith

Institution

University of North Carolina at Chapel Hill

genome instability

cellular senescence

Tariq Rana

Institution

University of California, San Diego

rna modification

medical virology

Cullen BR

Institution

Duke University

virology

immunology

Fatah Kashanchi

Institution

George Mason University

viral pathogenesis

human retroviruses

Charles E. Samuel

Institution

University of California, Santa Barbara

Ganes C. Sen

Institution

Case Western Reserve University

viral oncology

viral pathogenesis

Bryan Cullen

Institution

Duke University

virology

genetics

Similar Faculty Members

Craig E. Cameron

Institution

University of North Carolina at Chapel Hill

antiviral therapy

virus research

Robert H. Silverman

Institution

Case Western Reserve University

innate immune system

viral infections

Ronald Swanstrom

Institution

University of North Carolina at Chapel Hill

virology

general virology

Jack Griffith

Institution

University of North Carolina at Chapel Hill

genome instability

cellular senescence

Tariq Rana

Institution

University of California, San Diego

rna modification

medical virology

Cullen BR

Institution

Duke University

virology

immunology

Fatah Kashanchi

Institution

George Mason University

viral pathogenesis

human retroviruses

Charles E. Samuel

Institution

University of California, Santa Barbara

Ganes C. Sen

Institution

Case Western Reserve University

viral oncology

viral pathogenesis

Bryan Cullen

Institution

Duke University

virology

genetics