Faculty

Institution

Unit

Venue

Jack Griffith

Kenan Distinguished Professor

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Microbiology and Immunology

Jack Griffith is currently serving as a Microbiology And Immunology Kenan Distinguished Professor at University of North Carolina At Chapel Hill.

Honors

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Experiences

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Education

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Jack Griffith

University of North Carolina at Chapel Hill

Kenan Distinguished Professor

You can click a keyword to filter the displayed items

molecular biology biochemistry genetics structural biology structural molecular biology protein science nucleic acids protein structure gene expression biological chemistry cell biology dna replication dna repair biomolecular structure molecular cell biology genome biology virus research virology molecular genetics chromatin nuclear organization bacteriophages rna biology viral genetics electron microscopy molecular virology phage biology protein assembly mammalian biology chromatin remodeling sequence assembly biological macromolecules molecular structure vascular biology chromosome biology nucleic acid chemistry virus structure protein function cancer biology viral structural protein yeast mitochondrial biogenesis mitochondrial function biomolecules general virology gene structure electron microscope dna analysis gene function transcription regulation biomolecular interactions reca protein electron microscopic visualization peptide science oncogenes cancer genomics cellular biology dna sequencing genome instability protein x-ray crystallography protein biosynthesis protein synthesis duplex dna single-stranded dna-binding protein mammalian mitochondria telomeric dna single-stranded dna strand exchange holliday junctions replication forks extracellular vesicles chromatin structure sticky dna myotonic dystrophy gene kinetoplast dna dna loops cell aging aging cell cellular senescence carcinogenesis developmental biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cd81 Fusion Alters Sars-Cov-2 Spike Trafficking. mBio (2024)

Allaura S. ConeYijun ZhouRyan P. McNamaraAnthony. B. EasonGabriel F. AriasJustin T. LandisKyle W. ShifflettMeredith G. ChambersRunjie YuanSmaranda WillcoxJack D. GriffithDirk P. Dittmer

infectious diseasesvirologyimmunologyhost responsecell traffickingsars-cov-2covid-19spike traffickingvirus research

Linear Dna-Driven Recombination in Mammalian Mitochondria. Nucleic Acids Research (2024)

Georgios FragkoulisAnu HangasZsófia FeketeCraig MichellCarlos T MoraesSmaranda WillcoxJack D GriffithSteffi GoffartJaakko L O Pohjoismäki

biological engineeringgenetic engineeringmammalian mitochondriagenome biologylinear dna-driven recombinationmolecular biologymammalian biologyredox biologyrna biologygenetics

The Valine-Arginine Dipeptide Repeat Protein Encoded by Mammalian Telomeric Rna Appears Highly Expressed in Mitosis and May Repress Global Translation. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Taghreed M. Al-TurkiVenkata MantriSmaranda WillcoxC. Allie MillsLaura E. HerringSu-Ji ChoHannah LeeCailyn MeyerE. S. AntonJack D. Griffith

global translationtranscription (biology)molecular biologymammalian telomeric rnagene expression

Binding of Microrna-122 to the Hepatitis C Virus 5′ Untranslated Region Modifies Interactions With Poly(C) Binding Protein 2 and the Ns5B Viral Polymerase. Nucleic Acids Research (2023)

Seth ScottYou LiOya BermekJack D GriffithStanley M LemonKyung H Choi

protein expressionviral hepatitisvirologyvirus-host interactionsnucleic acidsmicrobiologymolecular biologymolecular virologygene expressionrna biologybiomolecular engineeringvirus research

Electron Microscopy Mapping of the Dna-Binding Sites of Monomeric, Dimeric, and Multimeric Kshv Rta Protein. Journal of Virology (2023)

Jayla C. CalhounBlossom DamaniaJack D. GriffithLindsey M. Costantini

virologyprotein scienceimmunologybiochemistrymolecular biologydna-binding sitesprotein structureviral geneticsstructural biologyviral structural proteinvirus research

Large‐Scale Heparin‐Based Bind‐and‐Elute Chromatography Identifies Two Biologically Distinct Populations of Extracellular Vesicles. Journal of Extracellular Vesicles (2023)

Yijun ZhouRunjie YuanAllaura S. ConeKyle W. ShifflettGabriel F. AriasAlice PengMeredith G. ChambersRyan P. McNamaraSmaranda WillcoxJustin T. LandisYue PanJack GriffithDirk P. Dittmer

membrane biologycell biologymolecular biologyextracellular vesicles

Mammalian Telomeric Rna (Terra) Can Be Translated to Produce Valine–Arginine and Glycine–Leucine Dipeptide Repeat Proteins. Proceedings of the National Academy of Sciences (2023)

Taghreed M. Al-TurkiJack D. Griffith

molecular and cellular biologymammalian telomeric rnaprotein scienceprotein biosynthesisbiochemistrygene regulationmammalian biologymolecular cell biologytranscription (biology)molecular biologygene functionprotein structureprotein synthesisgene expressionrna biologygenetics

Exosome-Encased Nucleic Acid Scaffold Chemotherapeutic Agents for Superior Anti-Tumor and Anti-Angiogenesis Activity. ACS Bio & Med Chem Au (2022)

Ryan P. McNamaraAnthony B. EasonYijun ZhouRachele BigiJack D. GriffithLindsey M. CostantiniMichelle A. RudekNicole M. AndersBlossom A. DamaniaDirk P. Dittmer

anti-cancer agentsanti-angiogenesis activitytumor biologyclinical chemistrycancer researchmolecular biologycancer treatmentbiomolecular engineeringradiation oncologynucleic acidsmedicinal researchmolecular cancermedicinal chemistryexosome-encased nucleic acidcancer carechemotherapeutic agentstumor targetingmolecular medicinenucleic acid amplificationcancer genomicsoncology

Imaging of Surface Microdomains on Individual Extracellular Vesicles in 3‐D. Journal of Extracellular Vesicles (2022)

Ryan P. McNamaraYijun ZhouAnthony B. EasonJustin T. LandisMeredith G. ChambersSmaranda WillcoxTiffany A. PetersonBlake SchouestNicholas J. ManessAndrew G. MacLeanLindsey M. CostantiniJack D. GriffithDirk Peter Dittmer

tissue imagingsurface microdomainsindividual extracellular vesiclesbiological imagingcell biology3d imaging

Peptide Amphiphile Supramolecular Nanofibers Designed to Target Abdominal Aortic Aneurysms. ACS Nano (2022)

Benjamin T. LedfordAdam W. AkermanKui SunDavid C. GillisJenna M. WeissJohnny VangSmaranda WillcoxTristan D. ClemonsHiroaki SaiRuomeng QiuMark R. KarverJack D. GriffithNick D. TsihlisSamuel I. StuppJohn S. IkonomidisMelina R. Kibbe

biological engineeringvascular biologypa nanofibersdrug deliverymatrix biologypeptide engineeringpeptide therapeuticsnanomedicineabdominal aortic aneurysmpeptide sciencepeptideslocalized dilationbiomedical engineeringnanoparticle researchextracellular matrixbiomolecular engineeringbiofabrication

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Jack Griffith

Kenan Distinguished Professor

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Microbiology and Immunology

Jack Griffith is currently serving as a Microbiology And Immunology Kenan Distinguished Professor at University of North Carolina At Chapel Hill.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jack Griffith

University of North Carolina at Chapel Hill

Kenan Distinguished Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cd81 Fusion Alters Sars-Cov-2 Spike Trafficking. mBio (2024)

Allaura S. ConeYijun ZhouRyan P. McNamaraAnthony. B. EasonGabriel F. AriasJustin T. LandisKyle W. ShifflettMeredith G. ChambersRunjie YuanSmaranda WillcoxJack D. GriffithDirk P. Dittmer

infectious diseasesvirologyimmunologyhost responsecell traffickingsars-cov-2covid-19spike traffickingvirus research

Linear Dna-Driven Recombination in Mammalian Mitochondria. Nucleic Acids Research (2024)

Georgios FragkoulisAnu HangasZsófia FeketeCraig MichellCarlos T MoraesSmaranda WillcoxJack D GriffithSteffi GoffartJaakko L O Pohjoismäki

biological engineeringgenetic engineeringmammalian mitochondriagenome biologylinear dna-driven recombinationmolecular biologymammalian biologyredox biologyrna biologygenetics

Taghreed M. Al-TurkiVenkata MantriSmaranda WillcoxC. Allie MillsLaura E. HerringSu-Ji ChoHannah LeeCailyn MeyerE. S. AntonJack D. Griffith

global translationtranscription (biology)molecular biologymammalian telomeric rnagene expression

Binding of Microrna-122 to the Hepatitis C Virus 5′ Untranslated Region Modifies Interactions With Poly(C) Binding Protein 2 and the Ns5B Viral Polymerase. Nucleic Acids Research (2023)

Seth ScottYou LiOya BermekJack D GriffithStanley M LemonKyung H Choi

protein expressionviral hepatitisvirologyvirus-host interactionsnucleic acidsmicrobiologymolecular biologymolecular virologygene expressionrna biologybiomolecular engineeringvirus research

Electron Microscopy Mapping of the Dna-Binding Sites of Monomeric, Dimeric, and Multimeric Kshv Rta Protein. Journal of Virology (2023)

Jayla C. CalhounBlossom DamaniaJack D. GriffithLindsey M. Costantini

virologyprotein scienceimmunologybiochemistrymolecular biologydna-binding sitesprotein structureviral geneticsstructural biologyviral structural proteinvirus research

Large‐Scale Heparin‐Based Bind‐and‐Elute Chromatography Identifies Two Biologically Distinct Populations of Extracellular Vesicles. Journal of Extracellular Vesicles (2023)

Yijun ZhouRunjie YuanAllaura S. ConeKyle W. ShifflettGabriel F. AriasAlice PengMeredith G. ChambersRyan P. McNamaraSmaranda WillcoxJustin T. LandisYue PanJack GriffithDirk P. Dittmer

membrane biologycell biologymolecular biologyextracellular vesicles

Mammalian Telomeric Rna (Terra) Can Be Translated to Produce Valine–Arginine and Glycine–Leucine Dipeptide Repeat Proteins. Proceedings of the National Academy of Sciences (2023)

Taghreed M. Al-TurkiJack D. Griffith

Exosome-Encased Nucleic Acid Scaffold Chemotherapeutic Agents for Superior Anti-Tumor and Anti-Angiogenesis Activity. ACS Bio & Med Chem Au (2022)

Ryan P. McNamaraAnthony B. EasonYijun ZhouRachele BigiJack D. GriffithLindsey M. CostantiniMichelle A. RudekNicole M. AndersBlossom A. DamaniaDirk P. Dittmer

Imaging of Surface Microdomains on Individual Extracellular Vesicles in 3‐D. Journal of Extracellular Vesicles (2022)

tissue imagingsurface microdomainsindividual extracellular vesiclesbiological imagingcell biology3d imaging

Peptide Amphiphile Supramolecular Nanofibers Designed to Target Abdominal Aortic Aneurysms. ACS Nano (2022)

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