Faculty

Institution

Unit

Venue

Cullen BR

Duke University

Affiliations

Duke University School of Medicine

Molecular Genetics & Microbiology

NoneCullen Br is currently serving as a Duke University School Of Medicine faculty at Duke University.

Honors

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Experiences

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Education

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Cullen BR

Duke University

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virology immunology genetics molecular biology hiv viral genetics gene expression virus research rna biology general virology molecular virology virus-host interactions cell biology viral evolution medical virology viral replication viral pathogenesis human retrovirus gene function genome biology protein science epigenetics gene therapy medicinal research transcription regulation molecular genetics genomics mammalian biology antiviral research immune responses molecular cell biology gene regulation viral oncology virus transmission avian biology molecular regulation clinical microbiology cellular biology gene vector human immunodeficiency virus molecular science molecular physiology crispr viral gene expression infection control nucleic acids rna processing epigenomics animal virus cancer biology gene editing nuclear export structural molecular biology host-microbe interactions cell regulation viral structural protein viral persistence activation domain functional characterization gene delivery developmental genetics sequence analysis protein expression transcriptomics technology antiviral therapy rev function viral micrornas rna interference mutational analysis short hairpin rnas mrna expression cell tropism placental alkaline phosphatase sequence requirements cellular micrornas alu retrotransposition

Notable Scholarly Works

Notable Federal Grants

Collaborators

Author Correction: Rna Conformational Propensities Determine Cellular Activity. Nature (2023)

Megan L. KenRohit RoyAinan GengLaura R. GanserAkanksha ManghraniBryan R. CullenUrsula Schulze-GahmenDaniel HerschlagHashim M. Al-Hashimi

cell biologymembrane biologycellular activityauthor correctionmolecular biologyrna conformational propensitiesrna biology

Genome Editing Using Staphylococcus Aureus Cas9 in a Canine Model of Glycogen Storage Disease Ia. Molecular Therapy — Methods & Clinical Development (2023)

Benjamin ArnsonHye Ri KangElizabeth D. BrooksDorothy GheorghiuEkaterina IlichDavid CourtneyJeffrey I. EverittBryan R. CullenDwight D. Koeberl

veterinary medicinegenome editinggeneticscanine model

Rna Conformational Propensities Determine Cellular Activity. Nature (2023)

Megan L. KenRohit RoyAinan GengLaura R. GanserAkanksha ManghraniBryan R. CullenUrsula Schulze-GahmenDaniel HerschlagHashim M. Al-Hashimi

cell biologycellular activitymolecular biologyrna conformational propensitiesgene expressionrna biology

The Smc5/6 Complex: An Emerging Antiviral Restriction Factor That Can Silence Episomal Dna. PLoS Pathogens (2023)

Ishak D. IrwanBryan R. Cullen

infectious diseasesvirologyepisomal dnaimmunologymicrobiologyantiviral restriction factor

Epigenetic Silencing by the Smc5/6 Complex Mediates Hiv-1 Latency. Nature Microbiology (2022)

Ishak D. IrwanHal P. BogerdBryan R. Cullen

viral pathogenesisinfectious diseasesvirologyvirus-host interactionsimmunologyhivepigeneticsepigenetic silencingmicrobiology

Epitranscriptomic Addition of M 6 a Regulates Hiv-1 Rna Stability and Alternative Splicing. Genes & Development (2021)

Kevin TsaiHal P. BogerdEdward M. KennedyAnn EmeryRonald SwanstromBryan R. Cullen

viral geneticsvirologyimmunologyhivepigeneticsalternative splicinggene functionmolecular biologyviral evolutionmolecular virologygeneral virologygene expressionepitranscriptomic additionrna biologygenetics

Mapping of Pseudouridine Residues on Cellular and Viral Transcripts Using a Novel Antibody-Based Technique. RNA (2021)

Cecilia Martinez CamposKevin TsaiDavid G. CourtneyHal P. BogerdChristopher L. HolleyBryan R. Cullen

virologyimmunologycell biologypseudouridine residuesmolecular biologynovel antibody-based techniqueviral transcriptstranscriptomics technologygene expressionrna biologybioinformatics

Mapping Rna Modifications Using Photo-Crosslinking-Assisted Modification Sequencing. Methods in molecular biology (2021)

Bryan R. CullenKevin Tsai

translational bioinformaticsgenomicsrna modificationsmolecular biologytranscriptomics technologygene expressionrna biologybioinformatics

Tax Induces the Recruitment of Nf-κB to Unintegrated Hiv-1 Dna to Rescue Viral Gene Expression and Replication. Journal of Virology (2021)

Ishak D. IrwanBryan R. Cullen

general virologyviral replicationvirologyviral geneticsvirus-host interactionsimmunologyhivdna replicationmolecular virologyviral evolutionreplicationgene expressionviral gene expressiongeneticsvirus research

Understanding the Role of Bulge‐Length Dependent Rna Stacking Energetics in Determining Hiv‐1 Tar‐Tat Peptide Binding Energetics in Vitro and in Cells. The FASEB Journal (2021)

Megan KellyRohit RoyHal BogerdDawn MerrimanLaura GanserBryan CullenHashim Al‐Hashimi

immunologyhivgeneticsclinical microbiologybulge-length dependent rnaenzymesviral replicationvirus-host interactionscell biologygeneral virologygene therapyvirologyviral geneticsrna biologyvirus researchprotein scienceantiviral researchmembrane biologymolecular virology

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Cullen BR

Duke University

Affiliations

Duke University School of Medicine

Molecular Genetics & Microbiology

NoneCullen Br is currently serving as a Duke University School Of Medicine faculty at Duke University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Cullen BR

Duke University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Author Correction: Rna Conformational Propensities Determine Cellular Activity. Nature (2023)

Megan L. KenRohit RoyAinan GengLaura R. GanserAkanksha ManghraniBryan R. CullenUrsula Schulze-GahmenDaniel HerschlagHashim M. Al-Hashimi

cell biologymembrane biologycellular activityauthor correctionmolecular biologyrna conformational propensitiesrna biology

Genome Editing Using Staphylococcus Aureus Cas9 in a Canine Model of Glycogen Storage Disease Ia. Molecular Therapy — Methods & Clinical Development (2023)

Benjamin ArnsonHye Ri KangElizabeth D. BrooksDorothy GheorghiuEkaterina IlichDavid CourtneyJeffrey I. EverittBryan R. CullenDwight D. Koeberl

veterinary medicinegenome editinggeneticscanine model

Rna Conformational Propensities Determine Cellular Activity. Nature (2023)

Megan L. KenRohit RoyAinan GengLaura R. GanserAkanksha ManghraniBryan R. CullenUrsula Schulze-GahmenDaniel HerschlagHashim M. Al-Hashimi

cell biologycellular activitymolecular biologyrna conformational propensitiesgene expressionrna biology

The Smc5/6 Complex: An Emerging Antiviral Restriction Factor That Can Silence Episomal Dna. PLoS Pathogens (2023)

Ishak D. IrwanBryan R. Cullen

infectious diseasesvirologyepisomal dnaimmunologymicrobiologyantiviral restriction factor

Epigenetic Silencing by the Smc5/6 Complex Mediates Hiv-1 Latency. Nature Microbiology (2022)

Ishak D. IrwanHal P. BogerdBryan R. Cullen

viral pathogenesisinfectious diseasesvirologyvirus-host interactionsimmunologyhivepigeneticsepigenetic silencingmicrobiology

Epitranscriptomic Addition of M 6 a Regulates Hiv-1 Rna Stability and Alternative Splicing. Genes & Development (2021)

Kevin TsaiHal P. BogerdEdward M. KennedyAnn EmeryRonald SwanstromBryan R. Cullen

Mapping of Pseudouridine Residues on Cellular and Viral Transcripts Using a Novel Antibody-Based Technique. RNA (2021)

Cecilia Martinez CamposKevin TsaiDavid G. CourtneyHal P. BogerdChristopher L. HolleyBryan R. Cullen

virologyimmunologycell biologypseudouridine residuesmolecular biologynovel antibody-based techniqueviral transcriptstranscriptomics technologygene expressionrna biologybioinformatics

Mapping Rna Modifications Using Photo-Crosslinking-Assisted Modification Sequencing. Methods in molecular biology (2021)

Bryan R. CullenKevin Tsai

translational bioinformaticsgenomicsrna modificationsmolecular biologytranscriptomics technologygene expressionrna biologybioinformatics

Tax Induces the Recruitment of Nf-κB to Unintegrated Hiv-1 Dna to Rescue Viral Gene Expression and Replication. Journal of Virology (2021)

Ishak D. IrwanBryan R. Cullen

Understanding the Role of Bulge‐Length Dependent Rna Stacking Energetics in Determining Hiv‐1 Tar‐Tat Peptide Binding Energetics in Vitro and in Cells. The FASEB Journal (2021)

Megan KellyRohit RoyHal BogerdDawn MerrimanLaura GanserBryan CullenHashim Al‐Hashimi

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molecular biology

mutagenesis (molecular biology technique)

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Joseph Sodroski

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Ganes C. Sen

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Garry Nolan

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gene discovery

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