Faculty

Institution

Unit

Venue

James S. Nowick

Professor

University of California, Irvine

Affiliations

School of Physical Sciences

Department of Chemistry

School of Pharmacy and Pharmaceutical Sciences

Department of Pharmaceutical Sciences

James S. Nowick is currently serving as a Chemistry Professor at University of California, Irvine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James S. Nowick

University of California, Irvine

Professor

You can click a keyword to filter the displayed items

chemistry molecular biology organic chemistry biochemistry structural biology protein science medicinal chemistry peptides alzheimer's disease biophysics chemical biology drug discovery crystallography x-ray crystallography protein structure chemical sciences peptide science protein chemistry peptide synthesis protein synthesis artificial b-sheets biomolecular structure molecular recognition peptide engineering x-ray crystallographic structure enzyme inhibition clinical chemistry supramolecular chemistry molecular design unnatural amino acid molecular scaffolds molecular science structural chemistry medicinal research molecular neurobiology synthetic chemistry nanoscale chemistry protein assembly neurochemistry tripeptide b-strand artificial b-sheet chemical models amyloid oligomers b-sheet peptides molecular neurodegeneration redox biology structural molecular biology virus research material chemistry biomolecular interactions protein x-ray crystallography pharmaceutical chemistry antiviral drug development supramolecular assemblies hydrogen bond enantioselective synthesis adenine-thymine base-pairing sds micelles macrocyclic b-hairpin peptides teixobactin pharmacophore x-ray crystallographic structures cyclic peptide inhibitor nanometer-sized amino acids biological chemistry synthesis methods rna biology molecular catalysis active ingredient combinatorial chemistry biological inorganic chemistry interactomics bioinformatics database protein bioinformatics structural bioinformatics ion exchange drug targeting molecular diversity natural product research biomolecular engineering general chemistry bioorganic chemistry amyloid diseases

Notable Scholarly Works

Notable Federal Grants

Collaborators

Amyloid-α Peptide Formed Through Alternative Processing of the Amyloid Precursor Protein Attenuates Alzheimer’s Amyloid-β Toxicity via Cross-Chaperoning. Journal of the American Chemical Society (2024)

Ariel J. KuhnKa ChanMaria SajimonStan YooVitor Hugo Balasco SerrãoJack LeeBenjamin AbramsJames S. NowickVladimir N. UverskyChristopher WheelerJevgenij A. Raskatov

amyloid-a peptidechemistryalzheimer's diseaseamyloid precursor proteinneurosciencealternative processingamyloid-b toxicitymolecular biology

A Turn for the Worse: Aβ β-Hairpins in Alzheimer’s Disease. Bioorganic & Medicinal Chemistry (2024)

Sarah M. RuttenbergJames S. Nowick

medicineclinical chemistryalzheimer's diseaseneurodegenerative diseasesmedicinal chemistrybioorganic chemistryneurosciencepharmacologyab b-hairpins

Correction to “Structure–Activity Relationship Studies of the Peptide Antibiotic Clovibactin”. The Journal of Organic Chemistry (2024)

Jackson E. H. BrunicardiJames H. GriffinMichael J. FerracaneAdam G. KreutzerJeramiah SmallAna-Teresa MendozaJoseph W. ZillerJames S. Nowick

peptide antibiotic clovibactinchemistryorganic chemistryantibioticsstructure-activity relationship studiespeptides

Drug Catalyzed Polymerization Yields One Pot Nanomedicines. RSC Applied Polymers (2024)

Paul Joshua HurstKyle J. GassawayMohammed Faris AbouchalehNehal S. IdrisChelsea R. JonesChris A. DicksionJames S. NowickJoseph P. Patterson

pharmaceutical technologypharmaceutical sciencesmedicinepharmaceutical nanotechnologytechnologypharmaceutical biotechnologymaterials sciencepolymer sciencetherapeutic nanomaterialsnanomedicinenanotechnology

Investigation of Isobactin Analogues of Teixobactin. ACS Medicinal Chemistry Letters (2024)

Chelsea R. JonesGrant H. LaiMaria Sophia Teresa Lee PadillaJames S. Nowick

isobactin analoguespharmaceutical chemistryclinical chemistrymedicinal chemistrypharmacologydrug discovery

Potent Analogues of Clovibactin From Commercially Available Amino Acid Building Blocks. (2024)

Jackson BrunicardiJeramiah SmallMaria Sophia Teresa Lee PadillaJovanna Carrera PlancarteJames Nowick

biomolecular engineeringchemical synthesismedicinal chemistryprotein sciencepeptide librarybiochemical engineeringpeptide synthesispeptide scienceorganic synthesisbiochemistryprotein synthesismolecular substratesmolecular biologydrug discoverypotent analoguesmedicinal research

Supramolecular Interactions of Teixobactin Analogues in the Crystal State. The Journal of Organic Chemistry (2024)

Hyunjun YangAdam G. KreutzerJames S. Nowick

chemistryorganic chemistryteixobactin analoguessupramolecular interactionspharmacologysupramolecular chemistrycrystal state

Teixobactin “Swapmers” With L Tail Stereochemistry Retain Antibiotic Activity. The Journal of Organic Chemistry (2024)

James H. GriffinAna-Teresa MendozaJames S. Nowick

antibiotic activityantibioticschemistryorganic chemistry

Α-Methylation Enables the X-Ray Crystallographic Observation of Oligomeric Assemblies Formed by a β-Hairpin Peptide Derived From Aβ. The Journal of Organic Chemistry (2024)

Tuan D. SamdinAdam G. KreutzerVictoria SahraiMichał WierzbickiJames S. Nowick

chemistryorganic chemistryb-hairpin peptidex-ray crystallographyoligomeric assembliesx-ray crystallographic observation

Antibodies Raised Against an Aβ Oligomer Mimic Recognize Pathological Features in Alzheimer’s Disease and Associated Amyloid-Disease Brain Tissue. ACS Central Science (2023)

Adam G. KreutzerChelsea Marie T. ParrochaSepehr HaerianardakaniGretchen GuaglianoneJennifer T. NguyenMichelle N. DiabWilliam YongMari Perez-RosendahlElizabeth HeadJames S. Nowick

antibody engineeringalzheimer's diseaseab oligomerimmunologypharmacologyneurologyamyloid-disease brain tissuepathological features

1
2
3
4
5
18
10 / page

James S. Nowick

Professor

University of California, Irvine

Affiliations

School of Physical Sciences

Department of Chemistry

School of Pharmacy and Pharmaceutical Sciences

Department of Pharmaceutical Sciences

James S. Nowick is currently serving as a Chemistry Professor at University of California, Irvine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James S. Nowick

University of California, Irvine

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Ariel J. KuhnKa ChanMaria SajimonStan YooVitor Hugo Balasco SerrãoJack LeeBenjamin AbramsJames S. NowickVladimir N. UverskyChristopher WheelerJevgenij A. Raskatov

amyloid-a peptidechemistryalzheimer's diseaseamyloid precursor proteinneurosciencealternative processingamyloid-b toxicitymolecular biology

A Turn for the Worse: Aβ β-Hairpins in Alzheimer’s Disease. Bioorganic & Medicinal Chemistry (2024)

Sarah M. RuttenbergJames S. Nowick

medicineclinical chemistryalzheimer's diseaseneurodegenerative diseasesmedicinal chemistrybioorganic chemistryneurosciencepharmacologyab b-hairpins

Correction to “Structure–Activity Relationship Studies of the Peptide Antibiotic Clovibactin”. The Journal of Organic Chemistry (2024)

Jackson E. H. BrunicardiJames H. GriffinMichael J. FerracaneAdam G. KreutzerJeramiah SmallAna-Teresa MendozaJoseph W. ZillerJames S. Nowick

peptide antibiotic clovibactinchemistryorganic chemistryantibioticsstructure-activity relationship studiespeptides

Drug Catalyzed Polymerization Yields One Pot Nanomedicines. RSC Applied Polymers (2024)

Paul Joshua HurstKyle J. GassawayMohammed Faris AbouchalehNehal S. IdrisChelsea R. JonesChris A. DicksionJames S. NowickJoseph P. Patterson

Investigation of Isobactin Analogues of Teixobactin. ACS Medicinal Chemistry Letters (2024)

Chelsea R. JonesGrant H. LaiMaria Sophia Teresa Lee PadillaJames S. Nowick

isobactin analoguespharmaceutical chemistryclinical chemistrymedicinal chemistrypharmacologydrug discovery

Potent Analogues of Clovibactin From Commercially Available Amino Acid Building Blocks. (2024)

Jackson BrunicardiJeramiah SmallMaria Sophia Teresa Lee PadillaJovanna Carrera PlancarteJames Nowick

Supramolecular Interactions of Teixobactin Analogues in the Crystal State. The Journal of Organic Chemistry (2024)

Hyunjun YangAdam G. KreutzerJames S. Nowick

chemistryorganic chemistryteixobactin analoguessupramolecular interactionspharmacologysupramolecular chemistrycrystal state

Teixobactin “Swapmers” With L Tail Stereochemistry Retain Antibiotic Activity. The Journal of Organic Chemistry (2024)

James H. GriffinAna-Teresa MendozaJames S. Nowick

antibiotic activityantibioticschemistryorganic chemistry

Α-Methylation Enables the X-Ray Crystallographic Observation of Oligomeric Assemblies Formed by a β-Hairpin Peptide Derived From Aβ. The Journal of Organic Chemistry (2024)

Tuan D. SamdinAdam G. KreutzerVictoria SahraiMichał WierzbickiJames S. Nowick

chemistryorganic chemistryb-hairpin peptidex-ray crystallographyoligomeric assembliesx-ray crystallographic observation

Antibodies Raised Against an Aβ Oligomer Mimic Recognize Pathological Features in Alzheimer’s Disease and Associated Amyloid-Disease Brain Tissue. ACS Central Science (2023)

Adam G. KreutzerChelsea Marie T. ParrochaSepehr HaerianardakaniGretchen GuaglianoneJennifer T. NguyenMichelle N. DiabWilliam YongMari Perez-RosendahlElizabeth HeadJames S. Nowick

antibody engineeringalzheimer's diseaseab oligomerimmunologypharmacologyneurologyamyloid-disease brain tissuepathological features

1
2
3
4
5
18
10 / page

Similar Faculty Members

Scott K Silverman

Institution

University of Illinois Urbana-Champaign

nucleic acid

biotechnology

Richard B. Silverman

Institution

Northwestern University

pharmacology

medicinal chemistry

Larry W. McLaughlin

Institution

Boston College

nucleic acid chemistry

dna sequences

Alanna Schepartz

Institution

University of California, Berkeley

chemical biology

molecular biology

Stephen Hanessian

Institution

University of California, Irvine

organic chemistry

medicinal chemistry

Paramjit Arora

Institution

New York University

bond formation

synthetic chemistry

Barbara Imperiali

Institution

Massachusetts Institute of Technology

biochemistry

molecular biology

Jianfeng Cai

Institution

University of South Florida

protein-protein interactions

biomolecular engineering

Paul R. Carlier

Institution

University of Illinois Chicago

infectious diseases (medical specialty)

malaria

Dale F. Mierke

Institution

Dartmouth College

high resolution nmr

biomolecular engineering

Similar Faculty Members

Scott K Silverman

Institution

University of Illinois Urbana-Champaign

nucleic acid

biotechnology

Richard B. Silverman

Institution

Northwestern University

pharmacology

medicinal chemistry

Larry W. McLaughlin

Institution

Boston College

nucleic acid chemistry

dna sequences

Alanna Schepartz

Institution

University of California, Berkeley

chemical biology

molecular biology

Stephen Hanessian

Institution

University of California, Irvine

organic chemistry

medicinal chemistry

Paramjit Arora

Institution

New York University

bond formation

synthetic chemistry

Barbara Imperiali

Institution

Massachusetts Institute of Technology

biochemistry

molecular biology

Jianfeng Cai

Institution

University of South Florida

protein-protein interactions

biomolecular engineering

Paul R. Carlier

Institution

University of Illinois Chicago

infectious diseases (medical specialty)

malaria

Dale F. Mierke

Institution

Dartmouth College

high resolution nmr

biomolecular engineering