Faculty

Institution

Unit

Venue

Larry W. McLaughlin

Professor of Chemistry

Boston College

Affiliations

Robert J. Morrissey College of Arts and Sciences

Chemistry Department

Larry W. Mclaughlin is currently serving as a Chemistry Professor of Chemistry at Boston College.

Honors

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Experiences

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Education

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Larry W. McLaughlin

Boston College

Professor of Chemistry

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molecular biology biochemistry biomolecular engineering structural biology genetics nucleic acids organic synthesis rna biology enzymes nucleic acid chemistry protein science chemical synthesis organic chemistry chemical biology molecular genetics nanotechnology structural molecular biology biological chemistry dna analysis oligonucleotides hammerhead ribozyme molecular science biomolecular structure coordination chemistry synthetic chemistry genome biology protein chemistry high-performance liquid chromatography transition metal chemistry structural chemistry dna sequencing enzyme catalysis yeast solution structure molecular structure biocatalysis dna nanotechnology liquid chromatography molecular dynamics efficient cleavage duplex stabilization chemical sciences biochemical sciences redox biology supramolecular chemistry molecular chemistry protein synthesis protein function molecular recognition bacteriophages phosphorothioate diesters dna curvature fluorescent dna oligomer mixed-mode chromatography molecular diagnostics supramolecular assemblies structural bioinformatics biomolecular interactions derivative (chemistry) functional modification biological inorganic chemistry chromatographic analysis bioconjugation bacteriology genome instability heterocyclic dna binding anticodon loop dna decamer magnesium binding fluorescence properties oligonucleotide-directed triplex formation enzyme inhibition molecular properties enzyme specificity protein purification dna sequences dna recognition dna replication

Notable Scholarly Works

Notable Federal Grants

Collaborators

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

biophysicsstructure elucidationcrystal researchcrystal diffraction studystructure determinationstructural chemistryccdc 2157502chemistrydeposited datasetcrystal engineeringchemical structurecrystal structurescrystallography

Effect of Terminal 3′-Hydroxymethyl Modification of an Rna Primer on Nonenzymatic Primer Extension. Chemical Communications (2016)

Ayan PalRajat S. DasWeicheng ZhangMegan LangLarry W. McLaughlinJack W. Szostak

medicinal chemistrychemical biotechnologyrna primermolecular biologychemistrynonenzymatic primer extensionrna biologybiochemistry

The Synthesis and Structural Characterization of Both Diastereomers of 5′-(Hydroxymethyl)-6,5′-Cyclo-2′,5′-Dideoxyuridine Cyclonucleosides. RSC Advances (2014)

Hongchuan YuMark K. SchlegelLarry W. McLaughlin

materials sciencestructural characterizationorganic synthesis

Cheminform Abstract: 2,3‐Dicyclohexylsuccinimide as a Directing/Protecting Group for the Regioselective Glycosylation or Alkylation of Purines.. ChemInform (2013)

Ayan PalKerry J. SalandriaJoseph W. AricoMark K. SchlegelLarry W. McLaughlin

organic chemistryregioselective glycosylationcheminform abstractorganic synthesischemistryglycosylation

Synthesis and Nmr Assignment of the Two Diastereomers of 8,6′-Cyclo-2′,6′-Dideoxyadenosine. Nucleosides Nucleotides & Nucleic Acids (2013)

Han YuehAyan PalKenneth ChangMark K. SchlegelLarry W. McLaughlin

immunologypharmacologynucleic acid chemistryorganic synthesisnmr assignmentnuclear magnetic resonancechemical synthesisbiochemistrynucleic acids

An Efficient Synthetic Approach to 6,5′-(S)- and 6,5′-(R)-Cyclouridine. Chemical Communications (2012)

Christopher S. TheileLarry W. McLaughlin

organic chemistryheterocycle chemistryorganic synthesissynthetic chemistrychemistrychemical synthesissynthetic biologyheterocyclic

Cheminform Abstract: An Efficient Synthetic Approach to 6,5′‐(S)‐ and 6,5′‐(R)‐Cyclouridine.. ChemInform (2012)

Christopher S. TheileLarry W. McLaughlin

cheminform abstractorganic synthesissynthetic chemistrychemistrychemical synthesis

Synthesis and Properties of Dna Containing Cyclonucleosides. Nucleosides Nucleotides & Nucleic Acids (2012)

Han YuehHongchuan YuChristopher S. TheileAyan PalAllen HorhotaNicholas GrecoCarl V. ChristiansonLarry W. McLaughlin

nucleic acid chemistrygeneticsdna analysismolecular biologychemical synthesisnucleic acids

Synthesis of 6,6′-(S)-Cyclo-2′-Deoxyuridine Featuring a Unique Barbier-Style Cyclization. RSC Advances (2012)

Christopher S. TheileLarry W. McLaughlin

heterocyclicchemical synthesischemistryorganic synthesis

Pyrovanadolysis, a Pyrophosphorolysis-Like Reaction Mediated by Pyrovanadate, Mn2+, and Dna Polymerase of Bacteriophage T7. Journal of Biological Chemistry (2011)

Barak AkabayovArkadiusz W. KulczykSabine R. AkabayovChristopher TheileLarry W. McLaughlinBenjamin BeauchampAntoine M. van OijenCharles C. Richardson

dna polymerasebacteriologypyrophosphorolysis-like reactionchemical biologyenzymesbacteriophagesmolecular biologybiological chemistrymicrobiologybiochemistry

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Larry W. McLaughlin

Professor of Chemistry

Boston College

Affiliations

Robert J. Morrissey College of Arts and Sciences

Chemistry Department

Larry W. Mclaughlin is currently serving as a Chemistry Professor of Chemistry at Boston College.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Larry W. McLaughlin

Boston College

Professor of Chemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

Effect of Terminal 3′-Hydroxymethyl Modification of an Rna Primer on Nonenzymatic Primer Extension. Chemical Communications (2016)

Ayan PalRajat S. DasWeicheng ZhangMegan LangLarry W. McLaughlinJack W. Szostak

medicinal chemistrychemical biotechnologyrna primermolecular biologychemistrynonenzymatic primer extensionrna biologybiochemistry

The Synthesis and Structural Characterization of Both Diastereomers of 5′-(Hydroxymethyl)-6,5′-Cyclo-2′,5′-Dideoxyuridine Cyclonucleosides. RSC Advances (2014)

Hongchuan YuMark K. SchlegelLarry W. McLaughlin

materials sciencestructural characterizationorganic synthesis

Cheminform Abstract: 2,3‐Dicyclohexylsuccinimide as a Directing/Protecting Group for the Regioselective Glycosylation or Alkylation of Purines.. ChemInform (2013)

Ayan PalKerry J. SalandriaJoseph W. AricoMark K. SchlegelLarry W. McLaughlin

organic chemistryregioselective glycosylationcheminform abstractorganic synthesischemistryglycosylation

Synthesis and Nmr Assignment of the Two Diastereomers of 8,6′-Cyclo-2′,6′-Dideoxyadenosine. Nucleosides Nucleotides & Nucleic Acids (2013)

Han YuehAyan PalKenneth ChangMark K. SchlegelLarry W. McLaughlin

immunologypharmacologynucleic acid chemistryorganic synthesisnmr assignmentnuclear magnetic resonancechemical synthesisbiochemistrynucleic acids

An Efficient Synthetic Approach to 6,5′-(S)- and 6,5′-(R)-Cyclouridine. Chemical Communications (2012)

Christopher S. TheileLarry W. McLaughlin

organic chemistryheterocycle chemistryorganic synthesissynthetic chemistrychemistrychemical synthesissynthetic biologyheterocyclic

Cheminform Abstract: An Efficient Synthetic Approach to 6,5′‐(S)‐ and 6,5′‐(R)‐Cyclouridine.. ChemInform (2012)

Christopher S. TheileLarry W. McLaughlin

cheminform abstractorganic synthesissynthetic chemistrychemistrychemical synthesis

Synthesis and Properties of Dna Containing Cyclonucleosides. Nucleosides Nucleotides & Nucleic Acids (2012)

Han YuehHongchuan YuChristopher S. TheileAyan PalAllen HorhotaNicholas GrecoCarl V. ChristiansonLarry W. McLaughlin

nucleic acid chemistrygeneticsdna analysismolecular biologychemical synthesisnucleic acids

Synthesis of 6,6′-(S)-Cyclo-2′-Deoxyuridine Featuring a Unique Barbier-Style Cyclization. RSC Advances (2012)

Christopher S. TheileLarry W. McLaughlin

heterocyclicchemical synthesischemistryorganic synthesis

Pyrovanadolysis, a Pyrophosphorolysis-Like Reaction Mediated by Pyrovanadate, Mn2+, and Dna Polymerase of Bacteriophage T7. Journal of Biological Chemistry (2011)

Barak AkabayovArkadiusz W. KulczykSabine R. AkabayovChristopher TheileLarry W. McLaughlinBenjamin BeauchampAntoine M. van OijenCharles C. Richardson

dna polymerasebacteriologypyrophosphorolysis-like reactionchemical biologyenzymesbacteriophagesmolecular biologybiological chemistrymicrobiologybiochemistry

1
2
3
4
5
19
10 / page

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Similar Faculty Members

John-Stephen Taylor

Institution

Washington University in St. Louis

breast cancer imaging

heat shock proteins

Marvin H. Caruthers

Institution

University of Colorado Boulder

molecular biology

biochemistry

Michael P. Stone

Institution

Vanderbilt University

molecular biology

biochemistry

Scott K Silverman

Institution

University of Illinois Urbana-Champaign

nucleic acid

biotechnology

Carmelo Rizzo

Institution

Vanderbilt University

molecular biology

mutagenesis

James Cowan

Institution

Ohio State University

metallodrug discovery

transition metal chemistry

Alanna Schepartz

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University of California, Berkeley

chemical biology

molecular biology

Charles E. McKenna

Institution

University of Southern California

future medicinal chemistry

medicinal chemistry

Douglas H. Turner

Institution

University of Rochester

nucleic acid chemistry

biomolecular structure

Ryan Mehl

Institution

Oregon State University

synthetic biology

biomolecular engineering