Faculty

Institution

Unit

Venue

James Manning

Emeritus faculty

Northeastern University

Affiliations

College of Science

Biology

James Manning is currently serving as a Biology Emeritus faculty at Northeastern University.

Honors

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Experiences

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Education

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James Manning

Northeastern University

Emeritus faculty

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biochemistry molecular biology protein science enzymes pharmacology protein chemistry structural biology biological chemistry biophysics protein structure membrane biology enzyme inhibition hematology enzyme catalysis medicinal chemistry chemical biology biochemical sciences redox biology biotechnology structural molecular biology peptides applied microbiology biological inorganic chemistry d-amino acid transaminase clinical microbiology biochemical genetics mammalian biology protein transport methyl acetyl phosphate cellular biochemistry yeast protein function protein expression biocatalysis protein genetics enzyme specificity molecular substrates enzymatic modification functional modification protein synthesis clinical biochemistry experimental medicine medicinal research heme homeostasis heme degradation heme trafficking structure-function enzyme kinetics polymerization kinetics biomolecular interactions protein purification amino groups amadori rearrangement alpha-amino groups subunit interfaces sickle hemoglobin clinical chemistry clinical investigation clinical evidence clinical physiology molecular regulation gene function epigenomics clinical medicine molecular catalysis experimental biology surface reactivity pharmaceutical chemistry d-amino acid aminotransferase l-amino acid residues sickle cell anemia bacterial growth pyridoxal phosphate recombinant hemoglobins acylpeptide hydrolase sickle cell hemoglobin fetal hemoglobins structural bioinformatics biomolecular structure protein structure prediction protein folding

Notable Scholarly Works

Notable Federal Grants

Collaborators

Embryonic and Fetal Human Hemoglobins: Structures, Oxygen Binding, and Physiological Roles. Sub-cellular biochemistry/Subcellular biochemistry (2020)

James M. ManningLois R. ManningAntoine DumoulinJulio C. PadovanBrian Chait

physiologyoxygen bindinggeneticsfetal human hemoglobinsembryonic stem cellsdevelopmental biologystructural biologyembryonic developmentembryology

Nano Gel Filtration Reveals How Fish Hemoglobins Release Oxygen: The Root Effect. Analytical Biochemistry (2020)

Lois R. ManningJames M. Manning

physiologyroot effectfish biologyavian biologyanimal physiologyredox biologymammalian biologytissue oxygenationfish hemoglobinsmolecular biologymembrane biologybiochemistry

Characterization of a Novel Cysteine-Rich Antifungal Protein From Fusarium Graminearum With Activity Against Maize Fungal Pathogens. International Journal of Food Microbiology (2018)

Belén PatiñoCovadonga VázquezJames M. ManningMaría Isabel G. RonceroDolores Córdoba-CañeroAntonio Di PietroÁlvaro Martínez-del-Pozo

fusarium graminearumbiotechnologymaize fungal pathogensfood microbiologymicrobiology

Phosphorylation of Serine Induces Lysine P K a Increases in Histone N-Termini and Signaling for Acetylation. Transcription Implications. Biochemistry (2018)

Lois R. ManningJames M. Manning

gene expressionpharmacologytranscription regulationcell signalingprotein phosphorylationtranscription factorstranscription implicationssignal transductionbiochemistry

Contributions to Nucleosome Dynamics in Chromatin From Interactive Propagation of Phosphorylation/Acetylation and Inducible Histone Lysine Basicities. Protein Science (2017)

Lois R. ManningJames M. Manning

biophysicsepigenomicsprotein structureprotein phosphorylationmolecular biologychromatinstructural biologyinteractive propagationprotein sciencebiochemistry

Gel Filtration of Dilute Human Embryonic Hemoglobins Reveals Basis for Their Increased Oxygen Binding. Analytical Biochemistry (2016)

Lois R. ManningAnthony M. PopowiczJulio C. PadovanBrian T. ChaitJames M. Manning

gel filtrationdevelopmental biologymembrane biologybiochemistrycell biology

Intrinsic Regulation of Hemoglobin Expression by Variable Subunit Interface Strengths. FEBS Journal (2011)

James M. ManningAnthony M. PopowiczJulio C. PadovanBrian T. ChaitLois R. Manning

hemoglobin expressionhematologysystems biologygeneticsmolecular regulationmolecular biologyintrinsic regulationmembrane biology

Chiral Discrimination Among Aminotransferases: Inactivation by 4-Amino-4,5-Dihydrothiophenecarboxylic Acid. Biochemistry (2010)

Bryan W. LeporeDali LiuYing PengMengmeng FuChad YasudaJames M. ManningRichard B. SilvermanDagmar Ringe

enzymeschiral discriminationbiochemistry

Developmental Expression of Human Hemoglobins Mediated by Maturation of Their Subunit Interfaces. Protein Science (2010)

Lois R. ManningAnthony M. PopowiczJulio PadovanBrian T. ChaitJ. Eric RussellJames M. Manning

subunit interfacesgeneticsdevelopmental expressiondevelopmental biologyprotein scienceprotein engineeringhuman hemoglobins

Energetic Differences at the Subunit Interfaces of Normal Human Hemoglobins Correlate With Their Developmental Profile. Biochemistry (2009)

Lois R. ManningJ. Eric RussellAnthony M. PopowiczRobert S. ManningJulio C. PadovanJames M. Manning

normal human hemoglobinsgene expressionsubunit interfacesdevelopmental profilemammalian biologydevelopmental biologyenergetic differencesbiochemistry

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James Manning

Emeritus faculty

Northeastern University

Affiliations

College of Science

Biology

James Manning is currently serving as a Biology Emeritus faculty at Northeastern University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James Manning

Northeastern University

Emeritus faculty

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Embryonic and Fetal Human Hemoglobins: Structures, Oxygen Binding, and Physiological Roles. Sub-cellular biochemistry/Subcellular biochemistry (2020)

James M. ManningLois R. ManningAntoine DumoulinJulio C. PadovanBrian Chait

physiologyoxygen bindinggeneticsfetal human hemoglobinsembryonic stem cellsdevelopmental biologystructural biologyembryonic developmentembryology

Nano Gel Filtration Reveals How Fish Hemoglobins Release Oxygen: The Root Effect. Analytical Biochemistry (2020)

Lois R. ManningJames M. Manning

physiologyroot effectfish biologyavian biologyanimal physiologyredox biologymammalian biologytissue oxygenationfish hemoglobinsmolecular biologymembrane biologybiochemistry

Characterization of a Novel Cysteine-Rich Antifungal Protein From Fusarium Graminearum With Activity Against Maize Fungal Pathogens. International Journal of Food Microbiology (2018)

Belén PatiñoCovadonga VázquezJames M. ManningMaría Isabel G. RonceroDolores Córdoba-CañeroAntonio Di PietroÁlvaro Martínez-del-Pozo

fusarium graminearumbiotechnologymaize fungal pathogensfood microbiologymicrobiology

Phosphorylation of Serine Induces Lysine P K a Increases in Histone N-Termini and Signaling for Acetylation. Transcription Implications. Biochemistry (2018)

Lois R. ManningJames M. Manning

gene expressionpharmacologytranscription regulationcell signalingprotein phosphorylationtranscription factorstranscription implicationssignal transductionbiochemistry

Contributions to Nucleosome Dynamics in Chromatin From Interactive Propagation of Phosphorylation/Acetylation and Inducible Histone Lysine Basicities. Protein Science (2017)

Lois R. ManningJames M. Manning

biophysicsepigenomicsprotein structureprotein phosphorylationmolecular biologychromatinstructural biologyinteractive propagationprotein sciencebiochemistry

Gel Filtration of Dilute Human Embryonic Hemoglobins Reveals Basis for Their Increased Oxygen Binding. Analytical Biochemistry (2016)

Lois R. ManningAnthony M. PopowiczJulio C. PadovanBrian T. ChaitJames M. Manning

gel filtrationdevelopmental biologymembrane biologybiochemistrycell biology

Intrinsic Regulation of Hemoglobin Expression by Variable Subunit Interface Strengths. FEBS Journal (2011)

James M. ManningAnthony M. PopowiczJulio C. PadovanBrian T. ChaitLois R. Manning

hemoglobin expressionhematologysystems biologygeneticsmolecular regulationmolecular biologyintrinsic regulationmembrane biology

Chiral Discrimination Among Aminotransferases: Inactivation by 4-Amino-4,5-Dihydrothiophenecarboxylic Acid. Biochemistry (2010)

Bryan W. LeporeDali LiuYing PengMengmeng FuChad YasudaJames M. ManningRichard B. SilvermanDagmar Ringe

enzymeschiral discriminationbiochemistry

Developmental Expression of Human Hemoglobins Mediated by Maturation of Their Subunit Interfaces. Protein Science (2010)

Lois R. ManningAnthony M. PopowiczJulio PadovanBrian T. ChaitJ. Eric RussellJames M. Manning

subunit interfacesgeneticsdevelopmental expressiondevelopmental biologyprotein scienceprotein engineeringhuman hemoglobins

Energetic Differences at the Subunit Interfaces of Normal Human Hemoglobins Correlate With Their Developmental Profile. Biochemistry (2009)

Lois R. ManningJ. Eric RussellAnthony M. PopowiczRobert S. ManningJulio C. PadovanJames M. Manning

normal human hemoglobinsgene expressionsubunit interfacesdevelopmental profilemammalian biologydevelopmental biologyenergetic differencesbiochemistry

1
2
3
4
5
16
10 / page

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Institution

University of Georgia

glycan trimming enzymes

glycosylation

Steven Clarke

Institution

University of California, Los Angeles

biochemistry

molecular biology

Michael A. Marletta

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University of California, Berkeley

biochemistry

enzymes

Julian Whitelegge

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molecular informatics

proteomic technologies

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mechanistic kinetics

Thomas Poulos

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Lai-Xi Wang

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