Faculty

Institution

Unit

Venue

James M. Dewar

Assistant Professor of Biochemistry

Vanderbilt University

Affiliations

School of Medicine

Department of Biochemistry

James M. Dewar is currently serving as a Biochemistry Assistant Professor of Biochemistry at Vanderbilt University.

Honors

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Experiences

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Education

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James M. Dewar

Vanderbilt University

Assistant Professor of Biochemistry

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genetics molecular biology dna repair cell biology dna replication replication gene expression genome biology developmental biology genomics cytogenetics structural biology protein science molecular cell biology avian biology dna replication termination vertebrate replication termination checkpoint activation genetic engineering genome editing biomolecular structure structural molecular biology medicinal research mammalian biology enzyme inhibition genomic mechanisms mechanism (biology) gene editing gene function poisoning experimental toxicology functional modification yeast semantic networks conflict management chromosome biology rna biology sequence assembly cell regulation cancer genetics cancer genomics animal reproduction replication-coupled proteolysis dna-protein crosslink replication-fork convergence g-quadruplex structures single-strand dna breaks vertebrate replisome replication termination actin dynamics enhancer analysis genomewide suppressor cellular processes dna double-strand breaks topoisomerase ii genome instability dna synthesis nucleic acid chemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

Control of Dna Replication in Vitro Using a Reversible Replication Barrier. Nature Protocols (2024)

Emma J. VontalgeTamar KavlashviliSteven N. DahmenMatthew T. CranfordJames M. Dewar

geneticsmolecular biologydna repairdna replicationreversible replication barrier

Dna Replication Recruits a Friend to Overcome a Challenging Break-Up. The EMBO Journal (2024)

James M Dewar

dna replicationmolecular biologybiology

Rtel1 and Mcm10 Overcome Topological Stress During Vertebrate Replication Termination. Cell Reports (2023)

Lillian V. CamposSabrina X. Van RavensteinEmma J. VontalgeBriana H. GreerDarren R. HeintzmanTamar KavlashviliW. Hayes McDonaldKristie Lindsey RoseBrandt F. EichmanJames M. Dewar

replicationgeneticsmolecular biologydna repairstructural biologyprotein sciencevertebrate replication terminationcell biology

Approaches to Monitor Termination of Dna Replication Using Xenopus Egg Extracts. Methods in molecular biology (2022)

Tamar KavlashviliJames M. Dewar

replicationavian biologyxenopus egg extractsgeneticsmolecular biologydna replication

Replication Fork Collapse in Vitro Using Xenopus Egg Extracts. Methods in enzymology on CD-ROM/Methods in enzymology (2022)

Sara C. ConwellMatthew T. CranfordTamar KavlashviliJames M. Dewar

replicationavian biologyxenopus egg extractsreplication fork collapsegeneticsanimal reproductiondevelopmental biologycell biology

Topoisomerase II Poisons Inhibit Vertebrate Dna Replication Through Distinct Mechanisms. The EMBO Journal (2022)

Sabrina X Van RavensteinKavi P MehtaTamar KavlashviliJo Ann W BylRunxiang ZhaoNeil OsheroffDavid CortezJames M Dewar

genome biologyfunctional modificationgene expressionpharmacologyenzyme inhibitionexperimental toxicologydistinct mechanismsgeneticsmammalian biologyvertebrate dna replicationmolecular biologytoxicologytopoisomerase ii poisonsdna replicationprotein sciencepoisoning

Single-Strand Dna Breaks Cause Replisome Disassembly. Molecular Cell (2021)

Kyle B VrtisJames M DewarGheorghe ChistolR Alex WuThomas G W GrahamJohannes C Walter

genomicssingle-strand dna breaksgeneticsmolecular biologydna repair

Uncoupling of the Replicative Helicase Induces Nascent Strand Degradation and Replication Fork Remodeling. The FASEB Journal (2021)

James DewarTamar Kavlashvili

molecular biologymolecular and cellular biologydevelopmental biology

Topoisomerase II is Crucial for Fork Convergence During Vertebrate Replication Termination. Cell Reports (2019)

Darren R. HeintzmanLillian V. CamposJo Ann W. BylNeil OsheroffJames M. Dewar

replicationtopoisomerase iimolecular biologyfork convergencedevelopmental biologyvertebrate replication terminationcell biology

Crl2 Lrr1 Promotes Unloading of the Vertebrate Replisome From Chromatin During Replication Termination. Genes & Development (2017)

James M. DewarEmily LowMatthias MannMarkus RäschleJohannes C. Walter

genome biologygene expressiondevelopmental biologyreplication terminationgeneticsgene functionvertebrate replisomemolecular biologychromatinepigenetics

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James M. Dewar

Assistant Professor of Biochemistry

Vanderbilt University

Affiliations

School of Medicine

Department of Biochemistry

James M. Dewar is currently serving as a Biochemistry Assistant Professor of Biochemistry at Vanderbilt University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James M. Dewar

Vanderbilt University

Assistant Professor of Biochemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Control of Dna Replication in Vitro Using a Reversible Replication Barrier. Nature Protocols (2024)

Emma J. VontalgeTamar KavlashviliSteven N. DahmenMatthew T. CranfordJames M. Dewar

geneticsmolecular biologydna repairdna replicationreversible replication barrier

Dna Replication Recruits a Friend to Overcome a Challenging Break-Up. The EMBO Journal (2024)

James M Dewar

dna replicationmolecular biologybiology

Rtel1 and Mcm10 Overcome Topological Stress During Vertebrate Replication Termination. Cell Reports (2023)

Lillian V. CamposSabrina X. Van RavensteinEmma J. VontalgeBriana H. GreerDarren R. HeintzmanTamar KavlashviliW. Hayes McDonaldKristie Lindsey RoseBrandt F. EichmanJames M. Dewar

replicationgeneticsmolecular biologydna repairstructural biologyprotein sciencevertebrate replication terminationcell biology

Approaches to Monitor Termination of Dna Replication Using Xenopus Egg Extracts. Methods in molecular biology (2022)

Tamar KavlashviliJames M. Dewar

replicationavian biologyxenopus egg extractsgeneticsmolecular biologydna replication

Replication Fork Collapse in Vitro Using Xenopus Egg Extracts. Methods in enzymology on CD-ROM/Methods in enzymology (2022)

Sara C. ConwellMatthew T. CranfordTamar KavlashviliJames M. Dewar

replicationavian biologyxenopus egg extractsreplication fork collapsegeneticsanimal reproductiondevelopmental biologycell biology

Topoisomerase II Poisons Inhibit Vertebrate Dna Replication Through Distinct Mechanisms. The EMBO Journal (2022)

Sabrina X Van RavensteinKavi P MehtaTamar KavlashviliJo Ann W BylRunxiang ZhaoNeil OsheroffDavid CortezJames M Dewar

Single-Strand Dna Breaks Cause Replisome Disassembly. Molecular Cell (2021)

Kyle B VrtisJames M DewarGheorghe ChistolR Alex WuThomas G W GrahamJohannes C Walter

genomicssingle-strand dna breaksgeneticsmolecular biologydna repair

Uncoupling of the Replicative Helicase Induces Nascent Strand Degradation and Replication Fork Remodeling. The FASEB Journal (2021)

James DewarTamar Kavlashvili

molecular biologymolecular and cellular biologydevelopmental biology

Topoisomerase II is Crucial for Fork Convergence During Vertebrate Replication Termination. Cell Reports (2019)

Darren R. HeintzmanLillian V. CamposJo Ann W. BylNeil OsheroffJames M. Dewar

replicationtopoisomerase iimolecular biologyfork convergencedevelopmental biologyvertebrate replication terminationcell biology

Crl2 Lrr1 Promotes Unloading of the Vertebrate Replisome From Chromatin During Replication Termination. Genes & Development (2017)

James M. DewarEmily LowMatthias MannMarkus RäschleJohannes C. Walter

genome biologygene expressiondevelopmental biologyreplication terminationgeneticsgene functionvertebrate replisomemolecular biologychromatinepigenetics

1
2
3
10 / page

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Similar Faculty Members

Toru M. Nakamura

Institution

University of Illinois Chicago

molecular biology

yeast

Zhongsheng You

Institution

Washington University in St. Louis

molecular biology

nonsense-mediated rna decay

David MacAlpine

Institution

Duke University

genome stability

replication fork

Kristin Eckert

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Pennsylvania State University

cancer letter

pathology

Duncan Smith

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New York University

molecular biology

epigenetics

Catherine Freudenreich

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Tufts University

molecular biology

genetics

Hannah L. Klein, PhD

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cancer genetics

Peter M. Burgers

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Washington University in St. Louis

dna sequencing

molecular biology

Michael Leffak

Institution

Wright State University

chromosome instability

genome instability

Oscar Aparicio

Institution

University of Southern California

nucleic acid

dna replication