Faculty

Institution

Unit

Venue

Eric Underbakke

Associate Professor

Iowa State University

Affiliations

College of Liberal Arts and Sciences

Biochemistry, Biophysics, and Molecular Biology

College of Agriculture and Life Sciences

Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology

Eric Underbakke is currently serving as a Biochemistry, Biophysics, And Molecular Biology Associate Professor at Iowa State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Eric Underbakke

Iowa State University

Associate Professor

You can click a keyword to filter the displayed items

enzymes protein science biochemistry pharmacology neuroscience membrane biology biophysics structural biology redox biology cell signaling structural molecular biology molecular neuroscience enzyme inhibition protein structure gene expression neurophysiology biological chemistry neurochemistry molecular physiology medicinal research protein expression functional regulation molecular regulation soluble guanylate cyclase biomolecular structure biochemical sciences molecular science biological inorganic chemistry conformational studies protein biosynthesis cellular neurobiology enzyme catalysis molecular imprinting receptor tyrosine kinases nuclear science nature method molecular structure structural chemistry theoretical biology mammalian biology biomolecular interactions heme trafficking heme signaling heme homeostasis heme transport single-molecule detection remedial action microbial genetics protein purification rna biology signal recognition enzyme specificity protein phosphorylation transcription regulation biochemical genetics pharmacokinetics molecular neurobiology protein mass spectrometry biological function cross-link gene regulation electron transfer calmodulin activation nitric oxide single-particle em higher-order domain architecture kinase domain oligomerization structural basis higher-order interactions catalytic domains nitric oxide receptor calmodulin-induced conformational control kinase activities selective inhibition peptide substrates isotope-coded affinity tags molecular cell biology cell biology signal transduction molecular biology multi-protein assembly protein assembly

Notable Scholarly Works

Notable Federal Grants

Collaborators

Molecularly Imprinted Nanoparticles Reveal Regulatory Scaffolding Features in Pyk2 Tyrosine Kinase. RSC Chemical Biology (2024)

Tania M. Palhano ZanelaMilad ZangiabadiYan ZhaoEric S. Underbakke

regulatory scaffolding featuresreceptor tyrosine kinasesmolecular imprintingprotein sciencecell signalingmolecular sciencemedicinal chemistrypharmacologymolecular biologymolecular engineeringsignal transductionbiomolecular engineering

Activation Loop Phosphorylation Tunes Conformational Dynamics Underlying Pyk2 Tyrosine Kinase Activation. Structure (2023)

Tania M. Palhano ZanelaAlexzandrea WoudenbergKaren G. Romero BelloEric S. Underbakke

biophysicsenzymesneurosciencemolecular biologyprotein structuresignal transductionstructural molecular biologystructural biology

Probing Protein Dynamics in Neuronal Nitric Oxide Synthase by Quantitative Cross-Linking Mass Spectrometry. Biochemistry (2023)

Ting JiangGuanghua WanHaikun ZhangYadav Prasad GyawaliEric S. UnderbakkeChangjian Feng

biophysicsprotein scienceneurosciencebiochemistryprotein dynamicsstructural biology

Intricate Coupling Between the Transactivation and Basic-Leucine Zipper Domains Governs Phosphorylation of Transcription Factor Atf4 by Casein Kinase 2. Journal of Biological Chemistry (2022)

Steven SiangEric S. UnderbakkeJulien Roche

protein expressionprotein phosphorylationstructural molecular biologygeneticsenzymesbasic-leucine zippercell signalingtranscription factorsintricate couplingtranscription regulationmolecular biologygene expressionprotein biosynthesisbiochemistrybiological chemistrybiochemical geneticsstructural biologyprotein sciencemolecular physiologymolecular cell biology

Controlling Kinase Activities by Selective Inhibition of Peptide Substrates. Journal of the American Chemical Society (2021)

Xiaowei LiTania M. Palhano ZanelaEric S. UnderbakkeYan Zhao

peptide substratesenzymeskinase activitiespharmacologyselective inhibition

Pyk2 Tyrosine Kinase Conformations Probed by Molecular Imprinted Nanoparticles. The FASEB Journal (2021)

Tania Palhano ZanelaXiaowei LiYan ZhaoEric Underbakke

biophysicsreceptor tyrosine kinasesmolecular imprintingnanotechnologypharmacologymolecular imprinted nanoparticles

Structural Basis for Alk2/Bmpr2 Receptor Complex Signaling Through Kinase Domain Oligomerization. Nature Communications (2021)

Christopher AgnewPelin AyazRisa KashimaHanna S. LovingPrajakta GhatpandeJennifer E. KungEric S. UnderbakkeYibing ShanDavid E. ShawAkiko HataNatalia Jura

kinase domain oligomerizationstructural molecular biologycell signalingimmunologycell biologymembrane biologypharmacologyprotein structurestructural basisreceptorsstructural biology

Conformational Dynamics of Ferm-Mediated Autoinhibition in Pyk2 Tyrosine Kinase. Biochemistry (2019)

Hanna S. LovingEric S. Underbakke

enzymesbiochemistryconformational dynamicspharmacologyferm-mediated autoinhibition

Mapping Regulatory Interactions in Proline‐Rich Tyrosine Kinase 2 by Cross‐Linking. The FASEB Journal (2019)

Natalie A. McClureHanna S. LovingEric S. Underbakke

regulatory interactionsenzymescross-linkphysiologyprotein sciencecell signalingredox biologycell biologybiological functionenzyme inhibitionfunctional regulationmolecular physiologymembrane biologypharmacologysignal transductionreceptorsmolecular regulation

N-Terminal Fusion of the N-Terminal Domain of Bacterial Enzyme I Facilitates Recombinant Expression and Purification of the Human Rna Demethylases Fto and Alkbh5. Protein Expression and Purification (2019)

Balabhadra KhatiwadaJeffrey A. PurslowEric S. UnderbakkeVincenzo Venditti

biological engineeringprotein expressionenzymeshuman rna demethylasesn-terminal domainn-terminal fusionprotein purificationbiotechnologyprotein engineeringmicrobial geneticsgene expressionrna biologybiomolecular engineeringgenetics

1
2
3
10 / page

Eric Underbakke

Associate Professor

Iowa State University

Affiliations

College of Liberal Arts and Sciences

Biochemistry, Biophysics, and Molecular Biology

College of Agriculture and Life Sciences

Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology

Eric Underbakke is currently serving as a Biochemistry, Biophysics, And Molecular Biology Associate Professor at Iowa State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Eric Underbakke

Iowa State University

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Molecularly Imprinted Nanoparticles Reveal Regulatory Scaffolding Features in Pyk2 Tyrosine Kinase. RSC Chemical Biology (2024)

Tania M. Palhano ZanelaMilad ZangiabadiYan ZhaoEric S. Underbakke

Activation Loop Phosphorylation Tunes Conformational Dynamics Underlying Pyk2 Tyrosine Kinase Activation. Structure (2023)

Tania M. Palhano ZanelaAlexzandrea WoudenbergKaren G. Romero BelloEric S. Underbakke

biophysicsenzymesneurosciencemolecular biologyprotein structuresignal transductionstructural molecular biologystructural biology

Probing Protein Dynamics in Neuronal Nitric Oxide Synthase by Quantitative Cross-Linking Mass Spectrometry. Biochemistry (2023)

Ting JiangGuanghua WanHaikun ZhangYadav Prasad GyawaliEric S. UnderbakkeChangjian Feng

biophysicsprotein scienceneurosciencebiochemistryprotein dynamicsstructural biology

Intricate Coupling Between the Transactivation and Basic-Leucine Zipper Domains Governs Phosphorylation of Transcription Factor Atf4 by Casein Kinase 2. Journal of Biological Chemistry (2022)

Steven SiangEric S. UnderbakkeJulien Roche

Controlling Kinase Activities by Selective Inhibition of Peptide Substrates. Journal of the American Chemical Society (2021)

Xiaowei LiTania M. Palhano ZanelaEric S. UnderbakkeYan Zhao

peptide substratesenzymeskinase activitiespharmacologyselective inhibition

Pyk2 Tyrosine Kinase Conformations Probed by Molecular Imprinted Nanoparticles. The FASEB Journal (2021)

Tania Palhano ZanelaXiaowei LiYan ZhaoEric Underbakke

biophysicsreceptor tyrosine kinasesmolecular imprintingnanotechnologypharmacologymolecular imprinted nanoparticles

Structural Basis for Alk2/Bmpr2 Receptor Complex Signaling Through Kinase Domain Oligomerization. Nature Communications (2021)

Christopher AgnewPelin AyazRisa KashimaHanna S. LovingPrajakta GhatpandeJennifer E. KungEric S. UnderbakkeYibing ShanDavid E. ShawAkiko HataNatalia Jura

kinase domain oligomerizationstructural molecular biologycell signalingimmunologycell biologymembrane biologypharmacologyprotein structurestructural basisreceptorsstructural biology

Conformational Dynamics of Ferm-Mediated Autoinhibition in Pyk2 Tyrosine Kinase. Biochemistry (2019)

Hanna S. LovingEric S. Underbakke

enzymesbiochemistryconformational dynamicspharmacologyferm-mediated autoinhibition

Mapping Regulatory Interactions in Proline‐Rich Tyrosine Kinase 2 by Cross‐Linking. The FASEB Journal (2019)

Natalie A. McClureHanna S. LovingEric S. Underbakke

Balabhadra KhatiwadaJeffrey A. PurslowEric S. UnderbakkeVincenzo Venditti

1
2
3
10 / page

Similar Faculty Members

Mark M Rasenick

Institution

University of Illinois Chicago

psychiatry

biological psychiatry

Gourisankar Ghosh

Institution

University of California, San Diego

mrna transport

gene expression

Brian E. Wadzinski

Institution

Vanderbilt University

biological chemistry

structure-function enzyme kinetics

James Wohlschlegel

Institution

University of California, Los Angeles

molecular informatics

bioinformatics

Craig C. Malbon

Institution

Stony Brook University

bioethics

philosophy

Michael A. Marletta

Institution

University of California, Berkeley

biochemistry

enzymes

Vann Bennett

Institution

Duke University

membrane biology

cell biology

LUBNA Tahtamouni

Institution

Colorado State University

neuroscience

cell biology

Charles R. Sanders

Institution

Vanderbilt University

protein misfolding

membrane protein

Eugenia V. Gurevich

Institution

Vanderbilt University

neuroscience

plastic changes

Similar Faculty Members

Mark M Rasenick

Institution

University of Illinois Chicago

psychiatry

biological psychiatry

Gourisankar Ghosh

Institution

University of California, San Diego

mrna transport

gene expression

Brian E. Wadzinski

Institution

Vanderbilt University

biological chemistry

structure-function enzyme kinetics

James Wohlschlegel

Institution

University of California, Los Angeles

molecular informatics

bioinformatics

Craig C. Malbon

Institution

Stony Brook University

bioethics

philosophy

Michael A. Marletta

Institution

University of California, Berkeley

biochemistry

enzymes

Vann Bennett

Institution

Duke University

membrane biology

cell biology

LUBNA Tahtamouni

Institution

Colorado State University

neuroscience

cell biology

Charles R. Sanders

Institution

Vanderbilt University

protein misfolding

membrane protein

Eugenia V. Gurevich

Institution

Vanderbilt University

neuroscience

plastic changes