Faculty

Institution

Unit

Venue

Carson Thoreen

Associate Professor

Yale University

Affiliations

Biological & Biomedical Sciences

Cellular & Molecular Physiology

Carson Thoreen is currently serving as a Biological & Biomedical Sciences Associate Professor at Yale University.

Honors

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Experiences

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Education

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Carson Thoreen

Yale University

Associate Professor

You can click a keyword to filter the displayed items

molecular biology pharmacology genetics gene expression signal transduction drug discovery membrane biology cell biology cell signaling protein science mammalian biology medicinal research rna biology tumor biology enzyme inhibition molecular regulation genomics medicinal chemistry transcription regulation molecular cell biology cell regulation pharmaceutical chemistry molecular physiology cellular physiology cell metabolism biological chemistry biochemical sciences genome biology gene regulation protein synthesis translational pharmacology biological inorganic chemistry drug targeting translational physiology mammalian physiology gene expression profiling atp-competitive mammalian target liver physiology cellular biochemistry developmental cell developmental science autophagy tissue development insulin signaling protein phosphorylation protein biosynthesis protein transport protein secretion receptor tyrosine kinases cytogenetics cellular biology sequence motif epigenomics tumor targeting drug targets cancer biology signaling pathways quality control biological evolution protein evolution cell growth tandem mass spectrometry large-scale protein analysis yeast proteome multidimensional chromatography protein ubiquitination mrna translation unifying model insulin-regulated inhibitor mtor inhibitor multiple myeloma cells human genome cytogenetic landmarks draft sequence post-transcriptional control dynamic features

Notable Scholarly Works

Notable Federal Grants

Collaborators

Larp1 Supports Brain Growth and Spatial Memory via Post-Transcriptional Control of the Translation Machinery. bioRxiv (Cold Spring Harbor Laboratory) (2025)

molecular neurosciencecortical remodelingmolecular cell biologyneuroscience

Using Spidrs to Map the Rna-Protein Web. Molecular Cell (2025)

Quantitative Profiling of Human Translation Initiation Reveals Elements That Potently Regulate Endogenous and Therapeutically Modified Mrnas. Molecular Cell (2024)

Cole J T LewisLi H XieShivani Milind BhandarkarDanni JinKyrillos AbdallahAustin S DraycottYixuan ChenCarson C ThoreenWendy V Gilbert

gene expressionmolecular cell biologytranscription (biology)systems biologymolecular regulationmolecular biologygene expression profilingquantitative profiling

Quantitative Profiling of Human Translation Initiation Reveals Regulatory Elements That Potently Affect Endogenous and Therapeutically Modified Mrnas. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Cole J.T. LewisLi XieShivani BhandarkarDanni JinKyrillos S. AbdallahAustin S. DraycottYixuan ChenCarson C. ThoreenWendy V. Gilbert

translational medicinegene expressiontranslational physiologybioinformaticsfunctional genomicsneurosciencepharmacologymembrane biologymammalian biologytranscription regulationmolecular biologygene expression profilingtranslational bioinformaticstranscriptomics technologyquantitative profiling

Measuring Mrna Decay With Roadblock‐Qpcr. Current Protocols (2022)

Maegan J. WatsonCarson C. Thoreen

mrna decaybioinformaticsrna biologybiostatistics

Mrna 5′ Terminal Sequences Drive 200-Fold Differences in Expression Through Effects on Synthesis, Translation and Decay. PLoS Genetics (2022)

Antonia M. G. van den ElzenMaegan J. WatsonCarson C. Thoreen

epigeneticsgeneticsgene expressionterminal sequencesgenomicsrna biologygenome biologymolecular biologyepigenetic changes

Split-Personality Inhibitors. Nature Chemical Biology (2021)

Carson C. Thoreen

split-personality inhibitorsharm reductionneurosciencepharmacologyproximate causebehavioural pharmacologyneuropsychopharmacologypersonality psychologypersonalitytreatment optionspsychiatryneuropharmacologychemical biologypsychopathologyindividualized medicinemedicinal researchcombined modality treatmentmolecular psychiatrypharmacotherapy

Author Correction: Cooperative Nutrient Accumulation Sustains Growth of Mammalian Cells. Scientific Reports (2020)

Sungmin SonMark M. StevensHui Xiao ChaoCarson ThoreenAaron M. HosiosLawrence D. SchweitzerYaochung WengKris WoodDavid SabatiniMatthew G. Vander HeidenScott Manalis

molecular and cellular biologycooperative nutrient accumulationauthor correctionnutrient physiologymammalian physiologyneurosciencemammalian cellspharmacologymembrane biologymammalian biologyanimal physiologyneurology

Controversies Around the Function of Larp1. RNA Biology (2020)

Andrea J. BermanCarson C. ThoreenZinaida DedeicJames ChettlePhilippe P. RouxSarah P. Blagden

geneticsgene expressionbiologyrna biologymolecular biology

CORRECTION: An Atp-Competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-Resistant Functions of Mtorc1.. Journal of Biological Chemistry (2020)

Carson C. ThoreenSeong A. KangJae Won ChangQingsong LiuJianming ZhangYi GaoLaurie J. ReichlingTaebo SimDavid M. SabatiniNathanael S. Gray

biomolecular interactionsdrug resistanceprotein sciencepharmacologygene expressionbiological chemistrymembrane biologydrug discoverybiological inorganic chemistryredox biologybiochemistrymedicinal researchpharmaceutical chemistrydrug targetingatp-competitive mammalian targetsignal transductionmolecular biologyenzyme inhibitionhost specificity

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Carson Thoreen

Associate Professor

Yale University

Affiliations

Biological & Biomedical Sciences

Cellular & Molecular Physiology

Carson Thoreen is currently serving as a Biological & Biomedical Sciences Associate Professor at Yale University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Carson Thoreen

Yale University

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Larp1 Supports Brain Growth and Spatial Memory via Post-Transcriptional Control of the Translation Machinery. bioRxiv (Cold Spring Harbor Laboratory) (2025)

molecular neurosciencecortical remodelingmolecular cell biologyneuroscience

Using Spidrs to Map the Rna-Protein Web. Molecular Cell (2025)

Quantitative Profiling of Human Translation Initiation Reveals Elements That Potently Regulate Endogenous and Therapeutically Modified Mrnas. Molecular Cell (2024)

Cole J T LewisLi H XieShivani Milind BhandarkarDanni JinKyrillos AbdallahAustin S DraycottYixuan ChenCarson C ThoreenWendy V Gilbert

gene expressionmolecular cell biologytranscription (biology)systems biologymolecular regulationmolecular biologygene expression profilingquantitative profiling

Quantitative Profiling of Human Translation Initiation Reveals Regulatory Elements That Potently Affect Endogenous and Therapeutically Modified Mrnas. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Cole J.T. LewisLi XieShivani BhandarkarDanni JinKyrillos S. AbdallahAustin S. DraycottYixuan ChenCarson C. ThoreenWendy V. Gilbert

Measuring Mrna Decay With Roadblock‐Qpcr. Current Protocols (2022)

Maegan J. WatsonCarson C. Thoreen

mrna decaybioinformaticsrna biologybiostatistics

Mrna 5′ Terminal Sequences Drive 200-Fold Differences in Expression Through Effects on Synthesis, Translation and Decay. PLoS Genetics (2022)

Antonia M. G. van den ElzenMaegan J. WatsonCarson C. Thoreen

epigeneticsgeneticsgene expressionterminal sequencesgenomicsrna biologygenome biologymolecular biologyepigenetic changes

Split-Personality Inhibitors. Nature Chemical Biology (2021)

Carson C. Thoreen

Author Correction: Cooperative Nutrient Accumulation Sustains Growth of Mammalian Cells. Scientific Reports (2020)

Sungmin SonMark M. StevensHui Xiao ChaoCarson ThoreenAaron M. HosiosLawrence D. SchweitzerYaochung WengKris WoodDavid SabatiniMatthew G. Vander HeidenScott Manalis

Controversies Around the Function of Larp1. RNA Biology (2020)

Andrea J. BermanCarson C. ThoreenZinaida DedeicJames ChettlePhilippe P. RouxSarah P. Blagden

geneticsgene expressionbiologyrna biologymolecular biology

CORRECTION: An Atp-Competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-Resistant Functions of Mtorc1.. Journal of Biological Chemistry (2020)

Carson C. ThoreenSeong A. KangJae Won ChangQingsong LiuJianming ZhangYi GaoLaurie J. ReichlingTaebo SimDavid M. SabatiniNathanael S. Gray

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