Faculty

Institution

Unit

Venue

Chellappan, Srikumar

University of South Florida

Affiliations

College of Arts and Sciences

School of Natural Sciences and Mathematics

Department of Molecular Biosciences

NoneChellappan, Srikumar is currently serving as a College Of Arts And Sciences faculty at University of South Florida.

Honors

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Experiences

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Education

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Chellappan, Srikumar

University of South Florida

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cell biology tumor biology oncogenes cancer biology cancer research cancer cells oncology cell signaling pharmacology molecular cancer medicinal research cell regulation molecular biology gene expression molecular cell biology signal transduction genetics transcription factors cancer genetics cancer treatment cell death cancer care nicotine molecular regulation thoracic oncology anti-cancer agents transcription regulation enzyme inhibition cancer growth cancer genomics apoptosis tumor targeting cellular therapy gene regulation vascular biology signaling pathways tumor suppressors cell cycle cancer immunotherapy angiogenesis pancreatic cancer pharmacotherapy molecular physiology biological chemistry cell proliferation oncogenic agent breast oncology protein science pharmacological research drug targeting gene function melanoma nicotinic acetylcholine receptors receptor (biochemistry) cellular biology tumor growth breast cancer cells rb function cell control biomolecular interactions transcription factor binding rb protein transcriptional activity nicotine-mediated cell proliferation stem-like cells cyclin-dependent kinases differential utilization histone modifications nicotinic acetylcholine receptor protein expression in vivo systems genitourinary cancers gene regulatory networks epithelial-mesenchymal transition cellular target tumor antigen

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cdk7 and Cdk9 Inhibition Interferes With Transcription, Translation, and Stemness, and Induces Cytotoxicity in Gbm Irrespective of Temozolomide Sensitivity. Neuro-Oncology (2023)

I BhutadaF KhambatiSY ChengDM TiekD DuckettH Lawrence...

neurologymedicineenzyme inhibitiontumor targetingtemozolomide sensitivitybrain tumor researchmolecular cancertranscription factorsneuropharmacologytumor suppressorsanti-cancer agentsinhibitory activityoncologyneuro-oncologyoncogenescancer treatmenttumor biologyneuroscience

Hdac11 Activity Contributes to Mek Inhibitor Escape in Uveal Melanoma. Cancer Gene Therapy (2022)

Sathya Neelature SriramareddyFernanda Faião-FloresMichael F. EmmonsBiswarup SahaSrikumar ChellappanClayton WyattInna SmalleyJonathan D. LichtMichael A. DuranteJ. William HarbourKeiran S. M. Smalley

gene therapymelanomacancer geneticsneurologymedicinetumor targetingcancer careuveal melanomamolecular cancercancer researchcancer immunotherapycancer treatmenttumor biologyinhibitor escapepharmacologypharmacotherapyoncologyoncogenesmedicinal researchskin cancer

Lifetime Ovulatory Years and Ovarian Cancer Gene Expression Profiles. Journal of Ovarian Research (2022)

Naoko SasamotoPaul A. StewartTianyi WangSean J. YoderSrikumar ChellappanJonathan L. HechtBrooke L. FridleyKathryn L. TerryShelley S. Tworoger

health sciencesovarian cancerlifetime ovulatory years

Abstract 1011: Tank Binding Kinase (Tbk1) Inhibitor Bx795 Impairs Anti-Tumor Efficacy of T Cells by Abrogating Granzyme and Perforin Mobilization. Cancer research (2020)

Fatema KhambatiJaya PadmanabhanSriKumar Chellappan

perforin mobilizationanti-tumor efficacycancer caremolecular cancercancer genomicsanti-cancer agentshealth sciencestumor suppressorstherapeutic targetscancer growthdrug targetingtumor biologyimmunotherapyimmunologyradiation oncologyoncologyclinical researchcancer cellsmedicinal researchcellular therapy

Abstract 378: Hdac Inhibition Enhances Mek Antagonist Therapy in Uveal Melanoma Through Combined Blockade of Yap, Akt and Rtk Signaling. Experimental and Molecular Therapeutics (2019)

Fernanda Faiao-FloresMichael EmmonsMichael DuranteBiswarup SahaBin FangJohn KoomenSrikumar ChellappanSilvya Maria-EnglerJonathan LichtWilliam HarbourKeiran Smalley

tumor targetingcancer careuveal melanomamolecular cancercancer genomicsanti-cancer agentshdac inhibitiondermatologyleukemiacancer researchurologytherapeutic targetscancer immunotherapyrtk signalingcancer treatmentpharmacologymek antagonist therapyclinical researchoncologymedicinal researchskin cancercellular therapy

Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Reports (2019)

Shengchen LinChongbiao HuangVenugopal GundaJianwei SunSrikumar P. ChellappanZengxun LiVictoria IzumiBin FangJohn KoomenPankaj K. SinghJihui HaoShengyu Yang

metastasiscell researchcell biologycell interactionshost factorsmolecular cell biologymitochondrial oxidative phosphorylationstructural biologycellular biologymembrane biologyinflammationmitochondrial actin filamentscell-matrix interactionstumor biologysystems biologyredox biologymitochondrial functioncancer cellscellular therapyneuroscience

Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on Pdac Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat Pdac. International Journal of Molecular Sciences (2019)

Marwa AlhothaliMevin MathewGeeta IyerHarshani R. LawrenceShengyu YangSrikumar ChellappanJaya Padmanabhan

cell signalingclinical pharmacologypotential strategyanti-cancer agentspdac cellscytotoxic effectsdermatologycancer researchdrug targetingcancer treatmenttherapeutic agentspharmacological researchimmunologyenzyme inhibitionpharmacologypharmacotherapydrug discoveryoncologyclinical researchmedicinal researchcellular therapy

Abstract 2052: A Novel Phd2/Vhl- Mediated Regulation of Yap1 and Its Role in Vascular Mimicry and Tumor Angiogenesis. Cancer research (2018)

Namrata Bora SinghalBiswarup SahaSrikumar Chellappan

vascular mimicrycancer caretumor angiogenesisvascular biologymolecular cancercancer biologyhealth sciencesviral oncologycancer researchcancer treatmentmolecular physiologycell regulationtumor biologyimmunologyreceptorsangiogenesispharmacologyoncologyclinical researchmedicinal research

Abstract 2310: Targeting Transcription-Associated Cdks is an Effective Way to Combat Glioblastoma and Medulloblastoma With Minimal Effect on Primary Neurons. Cancer research (2018)

Isha BhutadaSrikumar ChellappanJaya Padmanabhan

gene therapycancer geneticsminimal effecteffective wayprimary neuronsneuro-oncologyneurologymedicinetumor targetingcancer carecancer managementmolecular cancercancer genomicsanti-cancer agentscancer researchtumor biologytranscription-associated cdksbrain tumor researchoncologymedicinal researchcellular therapyneuroscience

Abstract 4701: Verteporfin Inhibits Surface Pd-L1 Expression in Triple-Negative Breast Cancer (Tnbc) Cells. Cancer research (2018)

Fatema KhambatiNeha JaiswalSrikumar ChellappanHatem Soliman

breast oncologycell biologytriple-negative breast cancercancer carecancer managementanti-cancer agentsbreast cancercancer biologyleukemiacancer researchverteporfin inhibitscancer treatmenttumor biologyenzyme inhibitionpharmacologyradiation oncologyoncologyclinical researchmedicinal researchcellular therapy

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Chellappan, Srikumar

University of South Florida

Affiliations

College of Arts and Sciences

School of Natural Sciences and Mathematics

Department of Molecular Biosciences

NoneChellappan, Srikumar is currently serving as a College Of Arts And Sciences faculty at University of South Florida.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Chellappan, Srikumar

University of South Florida

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cdk7 and Cdk9 Inhibition Interferes With Transcription, Translation, and Stemness, and Induces Cytotoxicity in Gbm Irrespective of Temozolomide Sensitivity. Neuro-Oncology (2023)

I BhutadaF KhambatiSY ChengDM TiekD DuckettH Lawrence...

Hdac11 Activity Contributes to Mek Inhibitor Escape in Uveal Melanoma. Cancer Gene Therapy (2022)

Sathya Neelature SriramareddyFernanda Faião-FloresMichael F. EmmonsBiswarup SahaSrikumar ChellappanClayton WyattInna SmalleyJonathan D. LichtMichael A. DuranteJ. William HarbourKeiran S. M. Smalley

Lifetime Ovulatory Years and Ovarian Cancer Gene Expression Profiles. Journal of Ovarian Research (2022)

Naoko SasamotoPaul A. StewartTianyi WangSean J. YoderSrikumar ChellappanJonathan L. HechtBrooke L. FridleyKathryn L. TerryShelley S. Tworoger

health sciencesovarian cancerlifetime ovulatory years

Abstract 1011: Tank Binding Kinase (Tbk1) Inhibitor Bx795 Impairs Anti-Tumor Efficacy of T Cells by Abrogating Granzyme and Perforin Mobilization. Cancer research (2020)

Fatema KhambatiJaya PadmanabhanSriKumar Chellappan

Abstract 378: Hdac Inhibition Enhances Mek Antagonist Therapy in Uveal Melanoma Through Combined Blockade of Yap, Akt and Rtk Signaling. Experimental and Molecular Therapeutics (2019)

Fernanda Faiao-FloresMichael EmmonsMichael DuranteBiswarup SahaBin FangJohn KoomenSrikumar ChellappanSilvya Maria-EnglerJonathan LichtWilliam HarbourKeiran Smalley

Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Reports (2019)

Shengchen LinChongbiao HuangVenugopal GundaJianwei SunSrikumar P. ChellappanZengxun LiVictoria IzumiBin FangJohn KoomenPankaj K. SinghJihui HaoShengyu Yang

Marwa AlhothaliMevin MathewGeeta IyerHarshani R. LawrenceShengyu YangSrikumar ChellappanJaya Padmanabhan

Abstract 2052: A Novel Phd2/Vhl- Mediated Regulation of Yap1 and Its Role in Vascular Mimicry and Tumor Angiogenesis. Cancer research (2018)

Namrata Bora SinghalBiswarup SahaSrikumar Chellappan

Abstract 2310: Targeting Transcription-Associated Cdks is an Effective Way to Combat Glioblastoma and Medulloblastoma With Minimal Effect on Primary Neurons. Cancer research (2018)

Isha BhutadaSrikumar ChellappanJaya Padmanabhan

Abstract 4701: Verteporfin Inhibits Surface Pd-L1 Expression in Triple-Negative Breast Cancer (Tnbc) Cells. Cancer research (2018)

Fatema KhambatiNeha JaiswalSrikumar ChellappanHatem Soliman

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proteomics

chemical cleavage mechanisms

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Vanderbilt University

immunology

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oncology

cancer research

Michael B. Yaffe

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dna damage response

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molecular medicine

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cancer biology

Jonathan D Licht

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pathology

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immunology

genetics

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