Faculty

Institution

Unit

Venue

Blake Hill

Professor and Chair Pharmaceutical Sciences

Medical College of Wisconsin

Affiliations

Biochemistry

Blake Hill is currently serving as a Biochemistry Professor and Chair Pharmaceutical Sciences at Medical College of Wisconsin.

Honors

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Experiences

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Education

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Blake Hill

Medical College of Wisconsin

Professor and Chair Pharmaceutical Sciences

You can click a keyword to filter the displayed items

molecular biology biochemistry biophysical chemistry structural biology vascular biology vascular disease mitochondrial function mitochondrial fission systems biology diabetes protein structure molecular cell biology endothelial dysfunction biophysical modeling gene regulation human resistance arteries genetics enzymes bioactive compounds therapeutic targets mechanobiology medicinal research peptide science peptides animal physiology mammalian biology autophagy protein science diabetes research mammalian physiology veterinary physiology homeostatic mechanisms mitochondrial dynamics mitochondrial biogenesis mitophagy molecular regulation biophysical aspect protein assembly dysglycemic conditions reduces vascular inflammation cardiac function endurance exercise polg mice mitochondrial homeostasis intramolecular regulation dynamin mechanoenzyme molecular mechanisms mitochondrial fusion membrane biology membrane bilayers cellular biochemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

Intramolecular Regulation of Fis1 Activity in Fission and Mitophagy. The FASEB Journal (2021)

Ugochukwu IhenachoJohn EgnerMegan HarwigBlake Hill

gene regulationsystems biologycell signalingmolecular and cellular biologymolecular regulationintramolecular regulationmolecular cell biologymolecular biologymitophagysignal transductionautophagybiochemistry

A Novel Fis1 Inhibiting Peptide Reverses Diabetic Endothelial Dysfunction in Human Resistance Arteries. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Kelsey A. NoldenMamatha KakarlaJohn M. EgnerJingli WangMegan C. HarwigVenkata K. PuppalaBenjamin C. HofeldLeggy A. ArnoldDavid Z. TrykallFrancis C. PetersonMichelle L. RobertsDavid M. JensonR. Blake HillMichael E. Widlansky

diabetespeptidespeptide sciencesystems biologyvascular biologytherapeutic targetsvascular diseasebioactive compoundsendothelial dysfunctionmolecular biologymedicinal researchhuman resistance arteriesbiochemistry

Suppressing or Blocking Fis1 Reverses Diabetic Endothelial Dysfunction in Human Resistance Arteries. (2020)

Mamatha KakarlaJohn M. EgnerJingli WangMegan C. HarwigKelsey MeachamVenkata K. PuppalaBenjamin C. HofeldLeggy A. ArnoldDavid Z. TrykallR. Blake HillMichael E. Widlansky

diabetesvascular biologyvascular diseaseendothelial dysfunctionhuman resistance arteriesdiabetes researchhealth sciences

Evidence That Endurance Exercise Improves Cardiac Function in Polg Mice. The FASEB Journal (2019)

Blake HillVivian FuGeorge UgrasTomas Prolla

physiologyendurance exercisemammalian physiologyanimal physiologyexercise physiologymammalian biologypolg micecardiac functionneuroscienceveterinary physiology

Abstract 14250: Fis1 Knockdown Rescues Vascular Monolayer Integrity and Reduces Vascular Inflammation Under Dysglycemic Conditions. Circulation (2018)

Mamatha KakarlaDavid TrykallJingli WangSudhi TyagiRong YingMegan HarwigJohn EgnerBlake HillMichael Widlansky

dysglycemic conditionsbiomedical engineeringvascular biologyvascular diseasereduces vascular inflammationinflammation

Phase Separation of the Variable Domain of Dynamin Related Protein 1 in Tmao Suggests a Role in Assembly. Biophysical Journal (2018)

Blake HillAmmon PoseyMehran BagheriNolan KennedyJames Harden

protein assemblybiophysical chemistrybiophysics

Reconstitution of a Tail‐Anchored Mitochondrial Membrane Protein. The FASEB Journal (2018)

Amber L. BakkumBlake Hill

biophysicsmembranesprotein structuremitochondrial functionmolecular biologymembrane proteinsstructural biologyprotein sciencemembrane biologybiochemistry

Srcp1 Conveys Resistance to Polyglutamine Aggregation. Molecular Cell (2018)

Stephanie SantarriagaHolly N. HaverAdam J. KanackAlicia S. FikejsSamantha L. SisonJohn M. EgnerJonathan R. BostromEmily R. SeminaryR. Blake HillBrian A. LinkAllison D. EbertK. Matthew Scaglione

geneticsmolecular cell biologyenzymesmolecular biologybiochemistry

Recruitment of Drp1 in Mitochondrial Fission. The FASEB Journal (2017)

John M EgnerAmber BakkumAlex GardnerBlake Hill

gene expressionmitochondrial fissionmolecular biologybiochemistrygene regulationcell biology

The B Domain of the Mitochondrial Fission Mechanoenzyme Drp1 is Intrinsically Disordered and Coacervates Under Crowding Conditions. The FASEB Journal (2017)

Blake HillAmmon PoseyMehran BagheriNolan KennedyMisha KhanJames Harden

biophysicsprotein structuremitochondrial functionmolecular biologymechanobiologystructural biologybiochemistry

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Blake Hill

Professor and Chair Pharmaceutical Sciences

Medical College of Wisconsin

Affiliations

Biochemistry

Blake Hill is currently serving as a Biochemistry Professor and Chair Pharmaceutical Sciences at Medical College of Wisconsin.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Blake Hill

Medical College of Wisconsin

Professor and Chair Pharmaceutical Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Intramolecular Regulation of Fis1 Activity in Fission and Mitophagy. The FASEB Journal (2021)

Ugochukwu IhenachoJohn EgnerMegan HarwigBlake Hill

A Novel Fis1 Inhibiting Peptide Reverses Diabetic Endothelial Dysfunction in Human Resistance Arteries. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Suppressing or Blocking Fis1 Reverses Diabetic Endothelial Dysfunction in Human Resistance Arteries. (2020)

Mamatha KakarlaJohn M. EgnerJingli WangMegan C. HarwigKelsey MeachamVenkata K. PuppalaBenjamin C. HofeldLeggy A. ArnoldDavid Z. TrykallR. Blake HillMichael E. Widlansky

diabetesvascular biologyvascular diseaseendothelial dysfunctionhuman resistance arteriesdiabetes researchhealth sciences

Evidence That Endurance Exercise Improves Cardiac Function in Polg Mice. The FASEB Journal (2019)

Blake HillVivian FuGeorge UgrasTomas Prolla

physiologyendurance exercisemammalian physiologyanimal physiologyexercise physiologymammalian biologypolg micecardiac functionneuroscienceveterinary physiology

Abstract 14250: Fis1 Knockdown Rescues Vascular Monolayer Integrity and Reduces Vascular Inflammation Under Dysglycemic Conditions. Circulation (2018)

Mamatha KakarlaDavid TrykallJingli WangSudhi TyagiRong YingMegan HarwigJohn EgnerBlake HillMichael Widlansky

dysglycemic conditionsbiomedical engineeringvascular biologyvascular diseasereduces vascular inflammationinflammation

Phase Separation of the Variable Domain of Dynamin Related Protein 1 in Tmao Suggests a Role in Assembly. Biophysical Journal (2018)

Blake HillAmmon PoseyMehran BagheriNolan KennedyJames Harden

protein assemblybiophysical chemistrybiophysics

Reconstitution of a Tail‐Anchored Mitochondrial Membrane Protein. The FASEB Journal (2018)

Amber L. BakkumBlake Hill

biophysicsmembranesprotein structuremitochondrial functionmolecular biologymembrane proteinsstructural biologyprotein sciencemembrane biologybiochemistry

Srcp1 Conveys Resistance to Polyglutamine Aggregation. Molecular Cell (2018)

Stephanie SantarriagaHolly N. HaverAdam J. KanackAlicia S. FikejsSamantha L. SisonJohn M. EgnerJonathan R. BostromEmily R. SeminaryR. Blake HillBrian A. LinkAllison D. EbertK. Matthew Scaglione

geneticsmolecular cell biologyenzymesmolecular biologybiochemistry

Recruitment of Drp1 in Mitochondrial Fission. The FASEB Journal (2017)

John M EgnerAmber BakkumAlex GardnerBlake Hill

gene expressionmitochondrial fissionmolecular biologybiochemistrygene regulationcell biology

The B Domain of the Mitochondrial Fission Mechanoenzyme Drp1 is Intrinsically Disordered and Coacervates Under Crowding Conditions. The FASEB Journal (2017)

Blake HillAmmon PoseyMehran BagheriNolan KennedyMisha KhanJames Harden

biophysicsprotein structuremitochondrial functionmolecular biologymechanobiologystructural biologybiochemistry

1
2
10 / page

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Similar Faculty Members

Jialing Lin

Institution

University of Oklahoma

translational research

pediatrics

Jonathan S. Marchant

Institution

Medical College of Wisconsin

pharmacology

autophagy

Theodore G Wensel

Institution

Baylor College of Medicine

biological chemistry

photoreceptor biology

David Bernlohr

Institution

University of Minnesota

metabolic disorder

health science

Jack Kaplan

Institution

University of Illinois Chicago

molecular biology

membrane protein

Henry Pownall

Institution

Weill Cornell Medicine

health science

atherosclerosis

Sakthivel Sadayappan, PhD, MBA

Institution

University of Cincinnati

metabolism

cardiomyopathy

Hiromi Sesaki

Institution

Johns Hopkins University

cell biology

molecular biology

Julian Borejdo

Institution

University of North Texas Health Science Center

augmentation

kinetics

Suresh K. Joseph

Institution

Thomas Jefferson University

proteomics

inositol trisphosphate receptor