Faculty

Institution

Unit

Venue

Suresh K. Joseph

Professor

Thomas Jefferson University

Affiliations

Sidney Kimmel Medical College

Pathology & Genomic Medicine

Suresh K. Joseph is currently serving as a Pathology & Genomic Medicine Professor at Thomas Jefferson University.

Honors

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Experiences

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Education

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Suresh K. Joseph

Thomas Jefferson University

Professor

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biochemistry molecular biology receptors cell signaling receptor (biochemistry) cell biology signal transduction biological chemistry membrane biology protein science liver physiology medicinal research biochemical sciences redox biology protein phosphorylation intracellular trafficking inhibitory activity receptor tyrosine kinases mitochondrial function biomolecular engineering protein structure vascular biology cellular physiology inositol trisphosphate receptors molecular physiology g protein-coupled receptor electrophysiology gene expression chemical biology enzyme inhibition peptides molecular cell biology cell metabolism structural molecular biology signaling pathways protein transport cellular biochemistry protein assembly molecular regulation cell death redox signaling mitochondrial dynamics wb rat epithelial cells reactive oxygen species biological inorganic chemistry hepatotoxicity bone metabolism membrane transport cell regulation molecular docking cardiac muscle inositol trisphosphate receptor inositol trisphosphate cell physiology molecular neurobiology apoptosis bioelectrochemistry intermediate host molecular immunology protein secretion cellular enzymology renal pathophysiology t-regulatory cell mitochondrial biogenesis inositol triphosphate cell survival isolated hepatocytes inositol polyphosphates rat liver phosphate-dependent glutaminase liver mitochondria redox regulation intracellular second messengers cyclic amp-dependent phosphorylation er-mitochondrial contacts molecular and cellular biology proteomics molecular genetics lysosomal degradation biochemical interaction protein function biochemical genetics biological function

Notable Scholarly Works

Notable Federal Grants

Collaborators

Transcriptional Regulation in the Absence of Inositol Trisphosphate Receptor Calcium Signaling. Frontiers in Cell and Developmental Biology (2024)

Michael YoungDavid M. BoothDavid SmithMarco TiganoGyӧrgy HajnόczkySuresh K. Joseph

biophysicscell signalingbiologytranscriptional regulationtranscription regulationmolecular biology

Erratum to: Msto1 is a Cytoplasmic Pro‐Mitochondrial Fusion Protein, Whose Mutation Induces Myopathy and Ataxia in Humans. EMBO Molecular Medicine (2023)

Aniko GalPeter BaliczaDavid WeaverShamim NaghdiSuresh K JosephPéter VárnaiTibor GyurisAttila HorváthLaszlo NagyErin L SeifertMaria Judit MolnarGyörgy Hajnóczky

medicinemolecular medicinemolecular biologyneuroscience

Micu1 Controls the Sensitivity of the Mitochondrial Ca2+ Uniporter to Activators and Inhibitors. Cell chemical biology (2023)

Macarena Rodríguez-PradosKai-Ting HuangKatalin MártaMelanie PaillardGyörgy CsordásSuresh K. JosephGyörgy Hajnóczky

cell signalingbiochemistryenzyme inhibitionmolecular biologypharmacologymitochondrial functionredox biology

Micu1 Regulates Mitochondrial Cristae Structure and Function Independently of the Mitochondrial Ca 2+ Uniporter Channel. Science Signaling (2023)

Dhanendra TomarManfred ThomasJoanne F. GarbinciusDevin W. KolmetzkyOniel SalikPooja JadiyaSuresh K. JosephApril C. CarpenterGyörgy HajnóczkyJohn W. Elrod

molecular and cellular biologycell signalingmitochondrial cristae structurecell biologysignaling pathwaysbiochemistryintracellular traffickingmitochondrial dynamicscytoskeletonmolecular cell biologymolecular biologymitochondrial functionsignal transductionmolecular regulationstructural biology

Fluorescence Imaging Detection of Nanodomain Redox Signaling Events at Organellar Contacts. STAR Protocols (2022)

David M. BoothPéter VárnaiSuresh K. JosephGyörgy Hajnóczky

organellar contactsfluorescenceredox signalingmolecular biology

Functional Determination of Calcium-Binding Sites Required for the Activation of Inositol 1,4,5-Trisphosphate Receptors. Proceedings of the National Academy of Sciences (2022)

Vikas ArigeLara E. TerryLarry E. WagnerSundeep MalikMariah R. BakerGuizhen FanSuresh K. JosephIrina I. SeryshevaDavid I. Yule

cell signalingcalcium-binding sitescell biologybiochemistryreceptor (biochemistry)molecular biologyfunctional determinationsignal transductionreceptors

Metabolic Adaptation to the Chronic Loss of Ca2+ Signaling Induced by Ko of Ip3 Receptors or the Mitochondrial Ca2+ Uniporter. Journal of Biological Chemistry (2021)

Michael P. YoungZachary T. SchugDavid M. BoothDavid I. YuleKatsuhiko MikoshibaGyӧrgy HajnόczkySuresh K. Joseph

metabolismmolecular metabolismmetabolic regulationmetabolic pathwaysbiochemistrycell metabolismbiologymetabolic remodelingmolecular biologyoxidative stressbiological chemistrymetabolic adaptationsignal transductionchronic loss

Oxidative Bursts of Single Mitochondria Mediate Retrograde Signaling Toward the Er. Molecular Cell (2021)

David M BoothPéter VárnaiSuresh K JosephGyörgy Hajnóczky

molecular and cellular biologymitochondrial biogenesiscell signalingreactive oxygen speciescell biologycellular physiologymitochondrial dynamicsbiochemistrycell metabolismredox signalingoxidative burstssingle mitochondria mediatemolecular biologyoxidative stressfree radical biologymitochondrial functionsignal transductionredox biology

Abstract 15070: Micu1 Regulates Mitochondrial Cristae Structure and Function Independent of the Mitochondrial Calcium Uniporter Channel. Circulation (2020)

Dhanendra TomarManfred ThomasJoanne GarbinciusDevin KolmetzkyOniel Salikpooja jadiyaSuresh K JosephApril C CarpenterGyorgy HajnoczkyJohn W Elrod

cardiovascular researchmitochondrial cristae structurecell biologymembrane proteinsmitochondrial dynamicsbiochemistrygene functionmolecular biologymitochondrial functionmolecular regulationstructural biology

Ip3 Receptor Isoforms Differently Regulate Er-Mitochondrial Contacts and Local Calcium Transfer. Nature Communications (2019)

Adam BartokDavid WeaverTünde GolenárZuzana NichtovaMáté KatonaSzáva BánsághiKamil J. AlzayadyV. Kaye ThomasHideaki AndoKatsuhiko MikoshibaSuresh K. JosephDavid I. YuleGyörgy CsordásGyörgy Hajnóczky

protein sciencenatureredox biologyelectrophysiologybiomolecular interactionsneurosciencereceptor (biochemistry)er-mitochondrial contactslocal calcium transfermembrane biologyprotein transportmolecular biologypharmacologymolecular neurosciencemitochondrial functiongene expressionreceptors

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Suresh K. Joseph

Professor

Thomas Jefferson University

Affiliations

Sidney Kimmel Medical College

Pathology & Genomic Medicine

Suresh K. Joseph is currently serving as a Pathology & Genomic Medicine Professor at Thomas Jefferson University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Suresh K. Joseph

Thomas Jefferson University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Transcriptional Regulation in the Absence of Inositol Trisphosphate Receptor Calcium Signaling. Frontiers in Cell and Developmental Biology (2024)

Michael YoungDavid M. BoothDavid SmithMarco TiganoGyӧrgy HajnόczkySuresh K. Joseph

biophysicscell signalingbiologytranscriptional regulationtranscription regulationmolecular biology

Erratum to: Msto1 is a Cytoplasmic Pro‐Mitochondrial Fusion Protein, Whose Mutation Induces Myopathy and Ataxia in Humans. EMBO Molecular Medicine (2023)

Aniko GalPeter BaliczaDavid WeaverShamim NaghdiSuresh K JosephPéter VárnaiTibor GyurisAttila HorváthLaszlo NagyErin L SeifertMaria Judit MolnarGyörgy Hajnóczky

medicinemolecular medicinemolecular biologyneuroscience

Micu1 Controls the Sensitivity of the Mitochondrial Ca2+ Uniporter to Activators and Inhibitors. Cell chemical biology (2023)

Macarena Rodríguez-PradosKai-Ting HuangKatalin MártaMelanie PaillardGyörgy CsordásSuresh K. JosephGyörgy Hajnóczky

cell signalingbiochemistryenzyme inhibitionmolecular biologypharmacologymitochondrial functionredox biology

Micu1 Regulates Mitochondrial Cristae Structure and Function Independently of the Mitochondrial Ca 2+ Uniporter Channel. Science Signaling (2023)

Dhanendra TomarManfred ThomasJoanne F. GarbinciusDevin W. KolmetzkyOniel SalikPooja JadiyaSuresh K. JosephApril C. CarpenterGyörgy HajnóczkyJohn W. Elrod

Fluorescence Imaging Detection of Nanodomain Redox Signaling Events at Organellar Contacts. STAR Protocols (2022)

David M. BoothPéter VárnaiSuresh K. JosephGyörgy Hajnóczky

organellar contactsfluorescenceredox signalingmolecular biology

Functional Determination of Calcium-Binding Sites Required for the Activation of Inositol 1,4,5-Trisphosphate Receptors. Proceedings of the National Academy of Sciences (2022)

Vikas ArigeLara E. TerryLarry E. WagnerSundeep MalikMariah R. BakerGuizhen FanSuresh K. JosephIrina I. SeryshevaDavid I. Yule

cell signalingcalcium-binding sitescell biologybiochemistryreceptor (biochemistry)molecular biologyfunctional determinationsignal transductionreceptors

Metabolic Adaptation to the Chronic Loss of Ca2+ Signaling Induced by Ko of Ip3 Receptors or the Mitochondrial Ca2+ Uniporter. Journal of Biological Chemistry (2021)

Michael P. YoungZachary T. SchugDavid M. BoothDavid I. YuleKatsuhiko MikoshibaGyӧrgy HajnόczkySuresh K. Joseph

Oxidative Bursts of Single Mitochondria Mediate Retrograde Signaling Toward the Er. Molecular Cell (2021)

David M BoothPéter VárnaiSuresh K JosephGyörgy Hajnóczky

Abstract 15070: Micu1 Regulates Mitochondrial Cristae Structure and Function Independent of the Mitochondrial Calcium Uniporter Channel. Circulation (2020)

Dhanendra TomarManfred ThomasJoanne GarbinciusDevin KolmetzkyOniel Salikpooja jadiyaSuresh K JosephApril C CarpenterGyorgy HajnoczkyJohn W Elrod

Ip3 Receptor Isoforms Differently Regulate Er-Mitochondrial Contacts and Local Calcium Transfer. Nature Communications (2019)

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