Faculty

Institution

Unit

Venue

Seock-Won Youn

Research Assistant Professor

University of Illinois Chicago

Affiliations

College of Medicine

Department of Physiology and Biophysics

Seock-won Youn is currently serving as a College Of Medicine Research Assistant Professor at University of Illinois Chicago.

Honors

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Experiences

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Education

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Seock-Won Youn

University of Illinois Chicago

Research Assistant Professor

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vascular biology cardiology angiogenesis pharmacology cell biology health sciences cardiovascular research hematology inflammation membrane biology liver physiology regenerative medicine cardiovascular physiology circulatory physiology immunology medicinal research endothelial dysfunction gene expression cellular physiology cell signaling cell death stem cell research redox biology applied physiology neovascularization cardiovascular function blood vessels enzyme inhibition free radical biology antioxidants hemostasis angiology vascular disease endothelial cells molecular physiology vascular adaptation redox signaling cellular therapy signaling pathways apoptosis cutaneous biology hypoxia (medicine) cell regulation heme homeostasis cardiomyopathy integrin-linked kinase animal physiology bioactive metal in vivo systems host factors vascular pharmacology heme signaling reperfusion injury myocardial infarction gene transfer mitochondrial function trace metals balloon injury transcription factor function cellular senescence molecular regulation cell physiology tissue development clinical therapeutics redox regulation copper transport smooth muscle cells adipokine resistin rabbit carotid artery key player direct conversion adult skin fibroblasts defined factors immediate early gene foxo3a transduction early stage real-time imaging systems biology genetic engineering cardiovascular disease

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cell-Type Specific Ribosomal Tagging Allows for Simultaneous Multi-Tissue Translatomic Analysis. bioRxiv (Cold Spring Harbor Laboratory) (2025)

computational biologybiomedical analysiscell biologysingle-cell analysismolecular cell biologysystems biologybioinformaticsmultiomics

Notch Signaling Regulates Unc5B to Suppress Endothelial Proliferation, Migration, Junction Activity, and Retinal Plexus Branching. Scientific Reports (2024)

Qanber RazaTaliha NadeemSeock-Won YounBhairavi SwaminathanAhana GuptaTimothy SargisJing DuHenar CuervoAnne EichmannSusan L. AckermanL. A. NaicheJan Kitajewski

vascular biologyangiogenesiscatalyst activationendothelial proliferationretinal plexus branchingcell signalingcell biologyneurosciencesignaling pathwaysmembrane biologysignal transductionmolecular neuroscienceophthalmologygene expressioncell regulationjunction activitycell migration

Abstract 4605: Chronic Vegf-C Signaling Exacerbates the Progression of Non-Alcoholic Steatohepatitis and Hepatocarcinoma Through Endothelial Vegfr2 and Vegfr3. Cancer Research (2023)

Seock-Won YounJason W.-L. EngBhairavi SwaminathanPamela TeneqexhiRahul VadakathJan K. Kitajewski

epidemiologyliver physiologyvascular biologycancer researchcancer treatmenthealth sciencesradiation oncologymedicinal researchmolecular cancercancer carecancer managementcancer biologyinflammationliver cancernon-alcoholic steatohepatitishepatologychronic vegf-c signalingcancer growthclinical researchoncology

Abstract 12127: Protein Disulfide Isomerase A1 as Novel Redox Sensor in Vegfr2 Signaling and Angiogenesis. Circulation (2022)

Sheela NagarkotiYoung-mee N KimDipankar AshArchita DasEric VitriolSeock-Won YounSudhahar VaradarajanMalgorzata McMenaminYali HouHarriet BoatwrightRuth B CaldwellDavid W EssexJaehyung ChoTohru FukaiMasuko Ushio-Fukai

cardiovascular researchvascular biologyregenerative medicinecardiologytumor biologycirculatory physiologyangiogenesisphysiologymedicinal researchredox signalinghemostasisbiochemistrymembrane biologypathway analysispharmacologygene expressionredox biologycardiovascular physiology

Abstract 12879: Endothelial Cu Exporter Atp7A Deficiency Promotes Cu-Dependent Endothelial-To-Mesenchymal Transition and Atherosclerosis via Orchestrating Glycolysis and Ros Signaling. Circulation (2022)

Dipankar AshSeock-Won YounSudhahar VaradarajanArchita DasYali HouMalgorzata McMenaminHarriet BoatwrightBradford G HillJack H KaplanMasuko Ushio-FukaiTohru Fukai

cardiovascular diseaseepidemiologyliver physiologyhyperlipidemiavascular biologyclinical lipidologynephrologycirculatory physiologyvascular diseaseatherosclerosishematologyhealth sciencescardiovascular physiologycardiologyendothelial dysfunctionglobal healthros signalingblood flowcardiovascular researchcu-dependent endothelial-to-mesenchymal transition

Abstract 3207: Notch Decoys as Potential Anti-Angiogenic Biotherapeutics. Cancer Research (2022)

Timothy SargisSeock-Won YounHyun LeeL.A. NaicheJan Kitajewski

vascular biologyradiation oncologyangiogenesistumor biologycancer researchmedicinecancer treatmentcancer careoncologycancer biology

Endothelial Notch Signaling Directly Regulates the Small Gtpase Rnd1 to Facilitate Notch Suppression of Endothelial Migration. Scientific Reports (2022)

Bhairavi SwaminathanSeock-Won YounL. A. NaicheJing DuStephanie R. VillaJordan B. MetzHuijuan FengChaolin ZhangRaphael KopanPeter A. SimsJan K. Kitajewski

vascular biologyendothelial migrationcell biologynotch suppressiondevelopmental biologymembrane biology

Exercise Improves Angiogenic Function of Circulating Exosomes in Type 2 Diabetes: Role of Exosomal Sod3. The FASEB Journal (2022)

Kareem AbdelsaidVaradarajan SudhaharRyan A. HarrisArchita DasSeock‐Won YounYutao LiuMaggie McMenaminYali HouDavid FultonMark W. HamrickYaoliang TangTohru FukaiMasuko Ushio‐Fukai

cardiovascular functionexercise physiologyproteomicsliver physiologydermatologyexercise scienceextracellular microvesiclesvascular biologycirculatory physiologycell biologyhematologyapplied physiologyhealth sciencesangiogenesiscellular physiologysport physiologyangiogenic functiondiabeteshepatology

Notch1 and Notch4 Core Binding Domain Peptibodies Exhibit Distinct Ligand-Binding and Anti-Angiogenic Properties. Angiogenesis (2022)

Timothy SargisSeock-Won YounKrishna ThakkarL. A. NaicheNa Yoon PaikKostandin V. PajciniJan K. Kitajewski

vascular biologyangiogenesisangiologyimmunologymedicinal researchhematologydevelopmental biologypharmacologyanti-angiogenic propertiesgene expression

Abstract P445: A Combinatorial Approach Comprehensively Improves the Maturation of Human Induced Pluripotent Stem Cell Derived Atrial Cardiomyocytes. Circulation Research (2021)

Olivia T LyGrace BrownHanna ChenLiang HongXinge WangYong Duk HanMahmud Arif PavelArvind SridharMark Maienschein-ClineSeock Won YounBrandon ChalazanMalek G Massadkhaled AbdelhadyJoseph C WuJalees RehmanSALMAN KHETANIDawood Darbar

regenerative medicinecardiologyangiogenesisatrial cardiomyocytesstem cell researchcell biologystem cellssynthetic biologymedicinal researchdevelopmental biologycell transplantationinduced pluripotent stem cellshuman geneticsgenetics

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Seock-Won Youn

Research Assistant Professor

University of Illinois Chicago

Affiliations

College of Medicine

Department of Physiology and Biophysics

Seock-won Youn is currently serving as a College Of Medicine Research Assistant Professor at University of Illinois Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Seock-Won Youn

University of Illinois Chicago

Research Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cell-Type Specific Ribosomal Tagging Allows for Simultaneous Multi-Tissue Translatomic Analysis. bioRxiv (Cold Spring Harbor Laboratory) (2025)

computational biologybiomedical analysiscell biologysingle-cell analysismolecular cell biologysystems biologybioinformaticsmultiomics

Notch Signaling Regulates Unc5B to Suppress Endothelial Proliferation, Migration, Junction Activity, and Retinal Plexus Branching. Scientific Reports (2024)

Qanber RazaTaliha NadeemSeock-Won YounBhairavi SwaminathanAhana GuptaTimothy SargisJing DuHenar CuervoAnne EichmannSusan L. AckermanL. A. NaicheJan Kitajewski

Abstract 4605: Chronic Vegf-C Signaling Exacerbates the Progression of Non-Alcoholic Steatohepatitis and Hepatocarcinoma Through Endothelial Vegfr2 and Vegfr3. Cancer Research (2023)

Seock-Won YounJason W.-L. EngBhairavi SwaminathanPamela TeneqexhiRahul VadakathJan K. Kitajewski

Abstract 12127: Protein Disulfide Isomerase A1 as Novel Redox Sensor in Vegfr2 Signaling and Angiogenesis. Circulation (2022)

Dipankar AshSeock-Won YounSudhahar VaradarajanArchita DasYali HouMalgorzata McMenaminHarriet BoatwrightBradford G HillJack H KaplanMasuko Ushio-FukaiTohru Fukai

Abstract 3207: Notch Decoys as Potential Anti-Angiogenic Biotherapeutics. Cancer Research (2022)

Timothy SargisSeock-Won YounHyun LeeL.A. NaicheJan Kitajewski

vascular biologyradiation oncologyangiogenesistumor biologycancer researchmedicinecancer treatmentcancer careoncologycancer biology

Endothelial Notch Signaling Directly Regulates the Small Gtpase Rnd1 to Facilitate Notch Suppression of Endothelial Migration. Scientific Reports (2022)

Bhairavi SwaminathanSeock-Won YounL. A. NaicheJing DuStephanie R. VillaJordan B. MetzHuijuan FengChaolin ZhangRaphael KopanPeter A. SimsJan K. Kitajewski

vascular biologyendothelial migrationcell biologynotch suppressiondevelopmental biologymembrane biology

Exercise Improves Angiogenic Function of Circulating Exosomes in Type 2 Diabetes: Role of Exosomal Sod3. The FASEB Journal (2022)

Kareem AbdelsaidVaradarajan SudhaharRyan A. HarrisArchita DasSeock‐Won YounYutao LiuMaggie McMenaminYali HouDavid FultonMark W. HamrickYaoliang TangTohru FukaiMasuko Ushio‐Fukai

Notch1 and Notch4 Core Binding Domain Peptibodies Exhibit Distinct Ligand-Binding and Anti-Angiogenic Properties. Angiogenesis (2022)

Timothy SargisSeock-Won YounKrishna ThakkarL. A. NaicheNa Yoon PaikKostandin V. PajciniJan K. Kitajewski

vascular biologyangiogenesisangiologyimmunologymedicinal researchhematologydevelopmental biologypharmacologyanti-angiogenic propertiesgene expression

Abstract P445: A Combinatorial Approach Comprehensively Improves the Maturation of Human Induced Pluripotent Stem Cell Derived Atrial Cardiomyocytes. Circulation Research (2021)

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