Faculty

Institution

Unit

Venue

Tohru Fukai

Professor

Augusta University

Affiliations

Medical College of Georgia

Department of Medicine

Department of Pharmacology & Toxicology

Tohru Fukai is currently serving as a Medicine Professor at Augusta University.

Honors

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Experiences

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Education

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Tohru Fukai

Augusta University

Professor

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vascular biology pharmacology physiology cardiology membrane biology health sciences liver physiology cardiovascular research hematology angiogenesis circulatory physiology redox biology cardiovascular physiology inflammation cell biology regenerative medicine cellular physiology cardiovascular disease free radical biology redox signaling oxidative stress medicinal research atherosclerosis endothelial dysfunction applied physiology vascular disease antioxidants angiology neovascularization cerebrovascular disease respiratory medicine enzyme inhibition thrombosis mammalian biology hemostasis extracellular superoxide dismutase endothelial cells novel role protein transport molecular physiology arterial disease heme homeostasis extracellular sod cell physiology metalloproteins human physiology bioactive metal tissue physiology reactive oxygen species mitochondrial function animal physiology cell migration renal function biological inorganic chemistry mammalian physiology cardiovascular function catalyst activation hindlimb ischemia clinical medicine trace metals copper transport post-ischemic neovascularization translational physiology angiotensin ii-induced hypertension clinical physiology cancer biology molecular regulation disease progression exercise training shear stress nadph oxidase vegf signaling angiotensin ii vascular injury neointimal formation nuclear translocation ayurveda alternative medicine diabetes research medicine yoga human health

Notable Scholarly Works

Notable Federal Grants

Collaborators

Endothelial Cu Uptake Transporter Ctr1 Senses Disturbed Flow to Promote Atherosclerosis Through Cuproptosis. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Varadarajan SudhaharZhen XiaoArchita DasDipankar AshShikha YadavCarson D. MatierAidan T. PezackiBarun ChatterjeeOlga A. AntipovaStefan VogtMalgorzata McMenaminStephanie KelleyGabor CsanyiJaekwon LeeHanjoong JoChristopher J. ChangJianghong RaoJack H. KaplanMasuko Ushio-FukaiTohru Fukai

biophysicscardiovascular diseasevascular biologycardiovascular researchvascular diseaseendothelial cuatherosclerosisendothelial dysfunctionmolecular biologysystems biologyblood flow

Pfkfb3 Connects Glycolytic Metabolism With Endothelial Dysfunction in Human and Rodent Obesity. Antioxidants (2025)

RK BatoriZ BordanCA PadgettY HuoF ChenRT AtawiaR Lucas...

metabolic syndromevascular biologymetabolismreactive oxygen speciesmetabolic regulationrodent obesitybiochemistryoxidative stressmetabolic healthantioxidantsobesity

Abstract 2074: De Novo Nucleotide Synthesis is Necessary for Dna Damage and Repair in Atheroprone Endothelial Cells. Arteriosclerosis Thrombosis and Vascular Biology (2024)

Qian MaQiuhua YangYongfeng CaiSudhahar VaradarajanZhidan ZhangTohru FukaiYuqing Huo

vascular biologybiochemistryendothelial dysfunctiondna damagemolecular biologydna repairatheroprone endothelial cells

Abstract 4142846: Endothelial Copper Uptake Transporter Ctr1 Senses Disturbed Flow to Promote Atherosclerosis Through Cuproptosis. Circulation (2024)

Sudhahar VaradarajanZhen XiaoArchita DasDipankar AshShikha YadavBarun ChatterjeeMalgorzata McMenaminStephanie KelleyJianghong RaoJack KaplanMasuko Ushio-FukaiTohru Fukai

cardiovascular diseasevascular biologycardiovascular researchphysiologyvascular diseaseatherosclerosisendothelial dysfunctioncardiovascular physiologyblood flow

Abstract 4143291: Macrophage Drp1 Sulfenylation Drives Neovascularization and Regeneration of Ischemic Muscle via Promoting Reparative Polarization and Metabolic Reprograming. Circulation (2024)

Shikha YadavSheela NagarkotiSudhahar VaradarajanArchita DasMalgorzata McMenaminStephanie KelleyTohru FukaiMasuko Ushio-Fukai

muscle functionneovascularizationvascular biologycirculatory physiologyphysiologywound healingcell biologymetabolic reprogramingcellular physiologybiochemistryischemic muscleskeletal musclevascular adaptationblood flowreparative polarizationregeneration (biology)inflammationregenerative medicineblood vessels

Abstract 4143778: Ros-Dependent Sumoylation of Copper Chaperone Atox1 Orchestrates Endothelial Inflammatory and Angiogenic Signaling, Promoting Neovascularization Following Ischemic Injury. Circulation (2024)

Archita DasSudhahar VaradarajanShikha YadavDavid FultonStephanie KelleyMalgorzata McMenaminJunichi AbeJack KaplanMasuko Ushio-FukaiTohru Fukai

cardiovascular diseaseredox signalingneovascularizationros-dependent sumoylationvascular biologyischemic injuryphysiologyvascular diseasecell biologycerebral blood flowoxidative stressangiogenesisendothelial inflammatorythrombosisendothelial dysfunctioninflammationblood vesselsmembrane biologyfree radical biologyredox biologyangiogenic signalingbiomolecular engineering

Altered Copper Transport in Oxidative Stress-Dependent Brain Endothelial Barrier Dysfunction Associated With Alzheimer's Disease. Vascular Pharmacology (2024)

Md Selim HossainArchita DasAshiq M RafiqFerenc DeákZsolt BagiRashelle OutlawVaradarajan SudhaharMai YamamotoJack H KaplanMasuko Ushio-FukaiTohru Fukai

neuropharmacologytrace metalsneuroscienceneurovascular diseasesvascular biologyalzheimer's diseasecopper transportneurodegenerative diseasescerebral blood flowoxidative stressmolecular neurodegenerationendothelial dysfunctionvascular cognitive disorderneurologyneuroscience of agingvascular pharmacologybrain injuryredox biologybiomolecular engineering

Endothelial Drp1 Couples Vegf-Induced Redox Signaling With Glycolysis Through Cysteine Oxidation to Drive Angiogenesis. Research Square (Research Square) (2024)

Masuko Ushio-FukaiSheela NagarkotiYoung-Mee KimArchita DasDipankar AshEric VitriolTracy-Ann ReadVaradarajan SudhaharMd. Selim HossainShikha YadavMalgorzata McMenaminStephanie KelleyRudolf LucasDavid SteppEric Belin de ChantemeleRuth CaldwellDavid FultonTohru Fukai

liver physiologycysteine oxidationredox signalingpharmacologyvascular biologycirculatory physiologyphysiologycell biologyhematologygene expressionangiogenesiscellular physiologyendothelial dysfunctionvascular adaptationtissue engineeringinflammationmembrane biologycatalyst activationredox biology

Endothelial Mitochondrial Gtpase Miro1 Protects Against Retinal Ischemia-Reperfusion-Induced Neurovascular Damage and Preserves Visual Function. Free Radical Biology and Medicine (2024)

Dipankar AshMai YamamotoYukika OishiMaggie McMenaminStephanie KelleyRuth CaldwellTohru FukaiMasuko Ushio-Fukai

neurovascular diseasesretinamedicinefree radical biology

Myeloid Drp1 Deficiency Limits Revascularization in Ischemic Muscles via Inflammatory Macrophage Polarization and Metabolic Reprograming. JCI Insight (2024)

Shikha YadavVijay C. GantaSudhahar VaradarajanVy OngYang ShiArchita DasDipankar AshSheela NagarkotiMalgorzata McMenaminStephanie KelleyTohru FukaiMasuko Ushio-Fukai

functional recoverymuscle functiondermatologyneurophysiologyischemic musclesgeneticsvascular biologyanimal physiologymotor controlinflammatory macrophage polarizationmetabolic reprogramingmedicinal researchcellular physiologymyelopoiesisvascular adaptationstrokerehabilitationinflammationregenerative medicinein vivo systemsmammalian biology

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Tohru Fukai

Professor

Augusta University

Affiliations

Medical College of Georgia

Department of Medicine

Department of Pharmacology & Toxicology

Tohru Fukai is currently serving as a Medicine Professor at Augusta University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Tohru Fukai

Augusta University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Endothelial Cu Uptake Transporter Ctr1 Senses Disturbed Flow to Promote Atherosclerosis Through Cuproptosis. bioRxiv (Cold Spring Harbor Laboratory) (2025)

biophysicscardiovascular diseasevascular biologycardiovascular researchvascular diseaseendothelial cuatherosclerosisendothelial dysfunctionmolecular biologysystems biologyblood flow

Pfkfb3 Connects Glycolytic Metabolism With Endothelial Dysfunction in Human and Rodent Obesity. Antioxidants (2025)

RK BatoriZ BordanCA PadgettY HuoF ChenRT AtawiaR Lucas...

metabolic syndromevascular biologymetabolismreactive oxygen speciesmetabolic regulationrodent obesitybiochemistryoxidative stressmetabolic healthantioxidantsobesity

Abstract 2074: De Novo Nucleotide Synthesis is Necessary for Dna Damage and Repair in Atheroprone Endothelial Cells. Arteriosclerosis Thrombosis and Vascular Biology (2024)

Qian MaQiuhua YangYongfeng CaiSudhahar VaradarajanZhidan ZhangTohru FukaiYuqing Huo

vascular biologybiochemistryendothelial dysfunctiondna damagemolecular biologydna repairatheroprone endothelial cells

Abstract 4142846: Endothelial Copper Uptake Transporter Ctr1 Senses Disturbed Flow to Promote Atherosclerosis Through Cuproptosis. Circulation (2024)

Sudhahar VaradarajanZhen XiaoArchita DasDipankar AshShikha YadavBarun ChatterjeeMalgorzata McMenaminStephanie KelleyJianghong RaoJack KaplanMasuko Ushio-FukaiTohru Fukai

cardiovascular diseasevascular biologycardiovascular researchphysiologyvascular diseaseatherosclerosisendothelial dysfunctioncardiovascular physiologyblood flow

Abstract 4143291: Macrophage Drp1 Sulfenylation Drives Neovascularization and Regeneration of Ischemic Muscle via Promoting Reparative Polarization and Metabolic Reprograming. Circulation (2024)

Shikha YadavSheela NagarkotiSudhahar VaradarajanArchita DasMalgorzata McMenaminStephanie KelleyTohru FukaiMasuko Ushio-Fukai

Archita DasSudhahar VaradarajanShikha YadavDavid FultonStephanie KelleyMalgorzata McMenaminJunichi AbeJack KaplanMasuko Ushio-FukaiTohru Fukai

Altered Copper Transport in Oxidative Stress-Dependent Brain Endothelial Barrier Dysfunction Associated With Alzheimer's Disease. Vascular Pharmacology (2024)

Md Selim HossainArchita DasAshiq M RafiqFerenc DeákZsolt BagiRashelle OutlawVaradarajan SudhaharMai YamamotoJack H KaplanMasuko Ushio-FukaiTohru Fukai

Endothelial Drp1 Couples Vegf-Induced Redox Signaling With Glycolysis Through Cysteine Oxidation to Drive Angiogenesis. Research Square (Research Square) (2024)

Endothelial Mitochondrial Gtpase Miro1 Protects Against Retinal Ischemia-Reperfusion-Induced Neurovascular Damage and Preserves Visual Function. Free Radical Biology and Medicine (2024)

Dipankar AshMai YamamotoYukika OishiMaggie McMenaminStephanie KelleyRuth CaldwellTohru FukaiMasuko Ushio-Fukai

neurovascular diseasesretinamedicinefree radical biology

Myeloid Drp1 Deficiency Limits Revascularization in Ischemic Muscles via Inflammatory Macrophage Polarization and Metabolic Reprograming. JCI Insight (2024)

Shikha YadavVijay C. GantaSudhahar VaradarajanVy OngYang ShiArchita DasDipankar AshSheela NagarkotiMalgorzata McMenaminStephanie KelleyTohru FukaiMasuko Ushio-Fukai

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