Faculty

Institution

Unit

Venue

Masuko Ushio-Fukai

Professor of Medicine

Augusta University

Affiliations

Medical College of Georgia

Department of Medicine

Masuko Ushio-fukai is currently serving as a Medicine Professor of Medicine at Augusta University.

Honors

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Experiences

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Education

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Masuko Ushio-Fukai

Augusta University

Professor of Medicine

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vascular biology pharmacology physiology membrane biology cardiology liver physiology redox biology angiogenesis cell biology cardiovascular research health sciences hematology circulatory physiology regenerative medicine inflammation cardiovascular physiology redox signaling cellular physiology oxidative stress free radical biology angiology medicinal research atherosclerosis cell signaling vascular disease antioxidants applied physiology neovascularization endothelial dysfunction cerebrovascular disease thrombosis hemostasis novel role enzyme inhibition stem cell research endothelial cells molecular physiology cell physiology protein transport angiotensin ii respiratory medicine cardiovascular function reactive oxygen species arterial disease biological chemistry tissue physiology cell migration metalloproteins mitochondrial function vascular smooth muscle bioactive metal in vivo systems human physiology renal function vascular pharmacology biological inorganic chemistry catalyst activation extracellular superoxide dismutase hindlimb ischemia cutaneous biology copper transport cancer biology translational physiology nadph oxidase angiotensin ii-induced hypertension clinical medicine protein phosphorylation cellular biology molecular regulation vascular function critical component nadph oxidase-derived ros vegf signaling redox regulation platelet activation neointimal formation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Endothelial Cu Uptake Transporter Ctr1 Senses Disturbed Flow to Promote Atherosclerosis Through Cuproptosis. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Varadarajan SudhaharZhen XiaoArchita DasDipankar AshShikha YadavCarson D. MatierAidan T. PezackiBarun ChatterjeeOlga A. AntipovaStefan VogtMalgorzata McMenaminStephanie KelleyGabor CsanyiJaekwon LeeHanjoong JoChristopher J. ChangJianghong RaoJack H. KaplanMasuko Ushio-FukaiTohru Fukai

biophysicsendothelial cublood flowsystems biologyvascular biologyendothelial dysfunctionvascular diseasecardiovascular researchmolecular biologyatherosclerosiscardiovascular disease

Pfkfb3 Connects Glycolytic Metabolism With Endothelial Dysfunction in Human and Rodent Obesity. Antioxidants (2025)

RK BatoriZ BordanCA PadgettY HuoF ChenRT AtawiaR Lucas...

metabolic healthmetabolismoxidative stressbiochemistryvascular biologyreactive oxygen speciesantioxidantsrodent obesitymetabolic regulationmetabolic syndromeobesity

Abstract 4142846: Endothelial Copper Uptake Transporter Ctr1 Senses Disturbed Flow to Promote Atherosclerosis Through Cuproptosis. Circulation (2024)

Sudhahar VaradarajanZhen XiaoArchita DasDipankar AshShikha YadavBarun ChatterjeeMalgorzata McMenaminStephanie KelleyJianghong RaoJack KaplanMasuko Ushio-FukaiTohru Fukai

cardiovascular physiologyblood flowvascular biologyendothelial dysfunctionphysiologyvascular diseasecardiovascular researchatherosclerosiscardiovascular disease

Abstract 4143291: Macrophage Drp1 Sulfenylation Drives Neovascularization and Regeneration of Ischemic Muscle via Promoting Reparative Polarization and Metabolic Reprograming. Circulation (2024)

Shikha YadavSheela NagarkotiSudhahar VaradarajanArchita DasMalgorzata McMenaminStephanie KelleyTohru FukaiMasuko Ushio-Fukai

skeletal musclecell biologymuscle functionmetabolic reprogramingvascular adaptationcirculatory physiologywound healingblood flowreparative polarizationbiochemistryvascular biologyphysiologyischemic muscleregeneration (biology)inflammationblood vesselsregenerative medicineneovascularizationcellular physiology

Abstract 4143778: Ros-Dependent Sumoylation of Copper Chaperone Atox1 Orchestrates Endothelial Inflammatory and Angiogenic Signaling, Promoting Neovascularization Following Ischemic Injury. Circulation (2024)

Archita DasSudhahar VaradarajanShikha YadavDavid FultonStephanie KelleyMalgorzata McMenaminJunichi AbeJack KaplanMasuko Ushio-FukaiTohru Fukai

cerebral blood flowcell biologyfree radical biologyendothelial dysfunctionvascular diseasecardiovascular diseaseoxidative stressischemic injuryangiogenesismembrane biologyredox biologyros-dependent sumoylationvascular biologyphysiologyendothelial inflammatorythrombosisredox signalinginflammationbiomolecular engineeringangiogenic signalingblood vesselsneovascularization

Altered Copper Transport in Oxidative Stress-Dependent Brain Endothelial Barrier Dysfunction Associated With Alzheimer's Disease. Vascular Pharmacology (2024)

Md Selim HossainArchita DasAshiq M RafiqFerenc DeákZsolt BagiRashelle OutlawVaradarajan SudhaharMai YamamotoJack H KaplanMasuko Ushio-FukaiTohru Fukai

cerebral blood flowneurodegenerative diseasesalzheimer's diseaseneuroscienceendothelial dysfunctioncopper transportoxidative stressmolecular neurodegenerationneurologyneuropharmacologyvascular pharmacologyneurovascular diseasesredox biologyvascular cognitive disordervascular biologytrace metalsbiomolecular engineeringneuroscience of agingbrain injury

Endothelial Drp1 Couples Vegf-Induced Redox Signaling With Glycolysis Through Cysteine Oxidation to Drive Angiogenesis. Research Square (Research Square) (2024)

Masuko Ushio-FukaiSheela NagarkotiYoung-Mee KimArchita DasDipankar AshEric VitriolTracy-Ann ReadVaradarajan SudhaharMd. Selim HossainShikha YadavMalgorzata McMenaminStephanie KelleyRudolf LucasDavid SteppEric Belin de ChantemeleRuth CaldwellDavid FultonTohru Fukai

cell biologypharmacologyendothelial dysfunctiongene expressionvascular adaptationliver physiologycirculatory physiologyangiogenesismembrane biologytissue engineeringredox biologyvascular biologyphysiologyredox signalinghematologycatalyst activationinflammationcysteine oxidationcellular physiology

Endothelial Mitochondrial Gtpase Miro1 Protects Against Retinal Ischemia-Reperfusion-Induced Neurovascular Damage and Preserves Visual Function. Free Radical Biology and Medicine (2024)

Dipankar AshMai YamamotoYukika OishiMaggie McMenaminStephanie KelleyRuth CaldwellTohru FukaiMasuko Ushio-Fukai

retinafree radical biologyneurovascular diseasesmedicine

Myeloid Drp1 Deficiency Limits Revascularization in Ischemic Muscles via Inflammatory Macrophage Polarization and Metabolic Reprograming. JCI Insight (2024)

Shikha YadavVijay C. GantaSudhahar VaradarajanVy OngYang ShiArchita DasDipankar AshSheela NagarkotiMalgorzata McMenaminStephanie KelleyTohru FukaiMasuko Ushio-Fukai

muscle functionfunctional recoverymammalian biologymyelopoiesisinflammatory macrophage polarizationmotor controlmetabolic reprogramingvascular adaptationstrokeneurophysiologyrehabilitationgeneticsvascular biologyanimal physiologymedicinal researchischemic musclesinflammationin vivo systemsdermatologyregenerative medicinecellular physiology

Novel Role of Copper Transporter Ctr1 and Therapeutic Potential of Copper Chelators in Retinal Ischemia-Reperfusion Injury. Free Radical Biology and Medicine (2024)

Mai YamamotoDipankar AshSudhahar VaradarajanSyed Adeel ZaidiModesto A. RojasZhimin XuMaggie McMenaminStephanie KelleyRuth CaldwellTohru FukaiMasuko Ushio-Fukai

radiation biologymedicinereactive oxygen speciesfree radical biologyophthalmologynovel roletumor biologyretinal ischemia-reperfusion injuryoxidative stressmembrane biologydrug discoverycopper chelatorsradiation oncologyredox biologyophthalmology retinaretinavascular biologymedicinal researchinflammationtherapeutic potentialocular surface physiologyreperfusion injury

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Masuko Ushio-Fukai

Professor of Medicine

Augusta University

Affiliations

Medical College of Georgia

Department of Medicine

Masuko Ushio-fukai is currently serving as a Medicine Professor of Medicine at Augusta University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Masuko Ushio-Fukai

Augusta University

Professor of Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Endothelial Cu Uptake Transporter Ctr1 Senses Disturbed Flow to Promote Atherosclerosis Through Cuproptosis. bioRxiv (Cold Spring Harbor Laboratory) (2025)

biophysicsendothelial cublood flowsystems biologyvascular biologyendothelial dysfunctionvascular diseasecardiovascular researchmolecular biologyatherosclerosiscardiovascular disease

Pfkfb3 Connects Glycolytic Metabolism With Endothelial Dysfunction in Human and Rodent Obesity. Antioxidants (2025)

RK BatoriZ BordanCA PadgettY HuoF ChenRT AtawiaR Lucas...

metabolic healthmetabolismoxidative stressbiochemistryvascular biologyreactive oxygen speciesantioxidantsrodent obesitymetabolic regulationmetabolic syndromeobesity

Abstract 4142846: Endothelial Copper Uptake Transporter Ctr1 Senses Disturbed Flow to Promote Atherosclerosis Through Cuproptosis. Circulation (2024)

Sudhahar VaradarajanZhen XiaoArchita DasDipankar AshShikha YadavBarun ChatterjeeMalgorzata McMenaminStephanie KelleyJianghong RaoJack KaplanMasuko Ushio-FukaiTohru Fukai

cardiovascular physiologyblood flowvascular biologyendothelial dysfunctionphysiologyvascular diseasecardiovascular researchatherosclerosiscardiovascular disease

Abstract 4143291: Macrophage Drp1 Sulfenylation Drives Neovascularization and Regeneration of Ischemic Muscle via Promoting Reparative Polarization and Metabolic Reprograming. Circulation (2024)

Shikha YadavSheela NagarkotiSudhahar VaradarajanArchita DasMalgorzata McMenaminStephanie KelleyTohru FukaiMasuko Ushio-Fukai

Archita DasSudhahar VaradarajanShikha YadavDavid FultonStephanie KelleyMalgorzata McMenaminJunichi AbeJack KaplanMasuko Ushio-FukaiTohru Fukai

Altered Copper Transport in Oxidative Stress-Dependent Brain Endothelial Barrier Dysfunction Associated With Alzheimer's Disease. Vascular Pharmacology (2024)

Md Selim HossainArchita DasAshiq M RafiqFerenc DeákZsolt BagiRashelle OutlawVaradarajan SudhaharMai YamamotoJack H KaplanMasuko Ushio-FukaiTohru Fukai

Endothelial Drp1 Couples Vegf-Induced Redox Signaling With Glycolysis Through Cysteine Oxidation to Drive Angiogenesis. Research Square (Research Square) (2024)

Endothelial Mitochondrial Gtpase Miro1 Protects Against Retinal Ischemia-Reperfusion-Induced Neurovascular Damage and Preserves Visual Function. Free Radical Biology and Medicine (2024)

Dipankar AshMai YamamotoYukika OishiMaggie McMenaminStephanie KelleyRuth CaldwellTohru FukaiMasuko Ushio-Fukai

retinafree radical biologyneurovascular diseasesmedicine

Myeloid Drp1 Deficiency Limits Revascularization in Ischemic Muscles via Inflammatory Macrophage Polarization and Metabolic Reprograming. JCI Insight (2024)

Shikha YadavVijay C. GantaSudhahar VaradarajanVy OngYang ShiArchita DasDipankar AshSheela NagarkotiMalgorzata McMenaminStephanie KelleyTohru FukaiMasuko Ushio-Fukai

Novel Role of Copper Transporter Ctr1 and Therapeutic Potential of Copper Chelators in Retinal Ischemia-Reperfusion Injury. Free Radical Biology and Medicine (2024)

Mai YamamotoDipankar AshSudhahar VaradarajanSyed Adeel ZaidiModesto A. RojasZhimin XuMaggie McMenaminStephanie KelleyRuth CaldwellTohru FukaiMasuko Ushio-Fukai

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