Faculty

Institution

Unit

Venue

Wesley Sundquist

Samuels Professor and Co-Chair of the Department of Biochemistry

University of Utah

Affiliations

Spencer Fox Eccles School of Medicine

Biochemistry

Wesley Sundquist is currently serving as a Biochemistry Samuels Professor and Co-Chair of the Department of Biochemistry at University of Utah.

Honors

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Experiences

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Education

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Wesley Sundquist

University of Utah

Samuels Professor and Co-Chair of the Department of Biochemistry

You can click a keyword to filter the displayed items

virology hiv immunology molecular biology structural biology protein structure protein science genetics cell biology viral genetics virus research structural molecular biology general virology viral structural protein virus-host interactions virus structure membrane biology medical virology viral evolution biomolecular structure biological chemistry gene expression molecular virology protein assembly enzymes molecular structure clinical microbiology antiviral research viral pathogenesis hiv budding molecular cell biology viral replication crystallography matrix biology crystal structures protein transport protein function structural basis developmental science mammalian biology human retrovirus antiviral therapy virus transmission host-microbe interactions retrovirus budding three-dimensional structure electron cryotomography medicinal research nature andrology molecular recognition cellular biology protein x-ray crystallography yeast structural bioinformatics biomolecular interactions biological inorganic chemistry human cyclophilin x-ray structures virus budding matrix protein ubiquitin interactions biochemical analyses tissue development embryonic development drug targeting microbial physiology virus phylogeny rna biology x-ray crystallography gene function guanine tetrads hairpin loops telomeric dna dimerizes protein network global landscape cell and molecular biology hiv restriction biomolecular engineering

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cell-Free Assays Reveal the Hiv-1 Capsid Protects Reverse Transcripts From Cgas. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Tiana M. ScottLydia M. ArnoldJordan A. PowersDelaney A. McCannAna B. RoweDevin E. ChristensenMiguel J. PereiraWen ZhouRachel M. TorrezJanet H. IwasaPhilip J. KranzuschWesley I. SundquistJarrod S. Johnson

virus researchhivvirus structurecell-free assaysmolecular biologyinfectious diseases

The Calpain-7 Protease Functions Together With the Escrt-III Protein Ist1 Within the Midbody to Regulate the Timing and Completion of Abscission. eLife (2023)

Elliott L PaineJack J SkalickyFrank G WhitbyDouglas R MackayKatharine S UllmanChristopher P HillWesley I Sundquist

protein functioncell signalingenzymesmolecular biologysignal transductionprotein sciencebiochemistrycell biology

Hiv-1 Preintegration Complex Preferentially Integrates the Viral Dna Into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Nicklas SappNathaniel BurgeKhan CoxSantosh ThapaPrem PrakashMuthukumar BalasubramaniamDevin ChristensonMin LiJared LinderbergerMamuka KvaratskheliaJui PandhareRobert CraigieWesley SundquistMichael G PoirierChandravanu Dash

immunologyhivviral dnaviral geneticsvirologymolecular biologycell biology

Recurrent Evolution of an Inhibitor of Escrt-Dependent Virus Budding and Line-1 Retrotransposition in Primates. Current Biology (2022)

Lara RheinemannDiane Miller DownhourKristen A. DavenportAlesia N. McKeownWesley I. SundquistNels C. Elde

escrt-dependent virus buddingvirologyviral evolutionrecurrent evolutionevolutionary biology

Identification of Abscission Checkpoint Bodies as Structures That Regulate Escrt Factors to Control Abscission Timing. eLife (2021)

Lauren K StrohackerDouglas R MackayMadeline A WhitneyGenevieve C CouldwellWesley I SundquistKatharine S Ullman

abscission timingescrt factorsneuroscienceabscission checkpoint bodiescell biology

Interactions Between Amot Ppxy Motifs and Nedd4L Ww Domains Function in Hiv-1 Release. Journal of Biological Chemistry (2021)

Lara RheinemannTuscan ThompsonGaelle MercenneElliott L. PaineFrancis C. PetersonBrian F. VolkmanSteven L. AlamAkram AlianWesley I. Sundquist

immunologyhivgene expressionpharmacologyvirus-host interactionscell signalinggeneral virologymolecular virologyviral geneticssequence motifvirologyamot ppxy motifsmolecular biologybiological chemistryviral structural proteinprotein science

Recurrent Emergence of an Antiviral Defense Through Repeated Retrotransposition and Truncation of Chmp3. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Lara RheinemannDiane Miller DownhourKristen A. DavenportAlesia N. McKeownWesley I. SundquistNels C. Elde

immunologyrecurrent emergencevirologyviral evolutionantiviral defense

Retrochmp3 Blocks Budding of Enveloped Viruses Without Blocking Cytokinesis. Cell (2021)

Lara RheinemannDiane Miller DownhourKate BredbennerGaelle MercenneKristen A. DavenportPhuong Tieu SchmittChristina R. NecessaryJohn McCulloughAnthony P. SchmittSanford M. SimonWesley I. SundquistNels C. Elde

enveloped virusesvirologydevelopmental biology

Stephan Oroszlan and the Proteolytic Processing of Retroviral Proteins: Following a Pro. Viruses (2021)

Ronald SwanstromWesley I. Sundquist

immunologyretroviral proteinsproteolytic processingvirologystephan oroszlan

Vaccinia Virus Hijacks Escrt-Mediated Multivesicular Body Formation for Virus Egress. Life Science Alliance (2021)

Moona HuttunenJerzy SamolejRobert J EvansArtur YakimovichIan J WhiteJanos Kriston-ViziJuan Martin-SerranoWesley I SundquistEva-Maria FrickelJason Mercer

viral persistencevirus-host interactionsvaccinia virusvirologyvirus egressmicrobiology

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Wesley Sundquist

Samuels Professor and Co-Chair of the Department of Biochemistry

University of Utah

Affiliations

Spencer Fox Eccles School of Medicine

Biochemistry

Wesley Sundquist is currently serving as a Biochemistry Samuels Professor and Co-Chair of the Department of Biochemistry at University of Utah.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Wesley Sundquist

University of Utah

Samuels Professor and Co-Chair of the Department of Biochemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cell-Free Assays Reveal the Hiv-1 Capsid Protects Reverse Transcripts From Cgas. bioRxiv (Cold Spring Harbor Laboratory) (2024)

virus researchhivvirus structurecell-free assaysmolecular biologyinfectious diseases

The Calpain-7 Protease Functions Together With the Escrt-III Protein Ist1 Within the Midbody to Regulate the Timing and Completion of Abscission. eLife (2023)

Elliott L PaineJack J SkalickyFrank G WhitbyDouglas R MackayKatharine S UllmanChristopher P HillWesley I Sundquist

protein functioncell signalingenzymesmolecular biologysignal transductionprotein sciencebiochemistrycell biology

Hiv-1 Preintegration Complex Preferentially Integrates the Viral Dna Into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification. bioRxiv (Cold Spring Harbor Laboratory) (2022)

immunologyhivviral dnaviral geneticsvirologymolecular biologycell biology

Recurrent Evolution of an Inhibitor of Escrt-Dependent Virus Budding and Line-1 Retrotransposition in Primates. Current Biology (2022)

Lara RheinemannDiane Miller DownhourKristen A. DavenportAlesia N. McKeownWesley I. SundquistNels C. Elde

escrt-dependent virus buddingvirologyviral evolutionrecurrent evolutionevolutionary biology

Identification of Abscission Checkpoint Bodies as Structures That Regulate Escrt Factors to Control Abscission Timing. eLife (2021)

Lauren K StrohackerDouglas R MackayMadeline A WhitneyGenevieve C CouldwellWesley I SundquistKatharine S Ullman

abscission timingescrt factorsneuroscienceabscission checkpoint bodiescell biology

Interactions Between Amot Ppxy Motifs and Nedd4L Ww Domains Function in Hiv-1 Release. Journal of Biological Chemistry (2021)

Lara RheinemannTuscan ThompsonGaelle MercenneElliott L. PaineFrancis C. PetersonBrian F. VolkmanSteven L. AlamAkram AlianWesley I. Sundquist

Recurrent Emergence of an Antiviral Defense Through Repeated Retrotransposition and Truncation of Chmp3. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Lara RheinemannDiane Miller DownhourKristen A. DavenportAlesia N. McKeownWesley I. SundquistNels C. Elde

immunologyrecurrent emergencevirologyviral evolutionantiviral defense

Retrochmp3 Blocks Budding of Enveloped Viruses Without Blocking Cytokinesis. Cell (2021)

enveloped virusesvirologydevelopmental biology

Stephan Oroszlan and the Proteolytic Processing of Retroviral Proteins: Following a Pro. Viruses (2021)

Ronald SwanstromWesley I. Sundquist

immunologyretroviral proteinsproteolytic processingvirologystephan oroszlan

Vaccinia Virus Hijacks Escrt-Mediated Multivesicular Body Formation for Virus Egress. Life Science Alliance (2021)

Moona HuttunenJerzy SamolejRobert J EvansArtur YakimovichIan J WhiteJanos Kriston-ViziJuan Martin-SerranoWesley I SundquistEva-Maria FrickelJason Mercer

viral persistencevirus-host interactionsvaccinia virusvirologyvirus egressmicrobiology

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innate immune system

viral infections

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structure-based immunogen design

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molecular informatics

biomolecular engineering

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