Faculty

Institution

Unit

Venue

David B. Smithrud

Associate Professor

University of Cincinnati

Affiliations

College of Arts and Sciences

Chemistry

David B. Smithrud is currently serving as a Chemistry Associate Professor at University of Cincinnati.

Honors

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Experiences

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Education

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David B. Smithrud

University of Cincinnati

Associate Professor

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chemistry pharmacology organic chemistry biomolecular engineering medicinal chemistry immunology organic synthesis cancer research protein science bioorganic chemistry oncology chemical biology chemical synthesis medicinal research host-guest chemistry protein transport antibody engineering intracellular trafficking condensation reactions peptides biological chemistry cellular therapy cancer cells pharmacotherapy cell metabolism cancer biology anti-cancer agents liver cancer antibody ligase cytotoxic agents facile synthesis cellular transport agents intracellular delivery intracellular transport mechanism protein binding domains molecular cancer vascular biology clinical chemistry enzyme inhibition toxins pharmacological research cartilage oncogenes nanometrology nanobiotechnology sensor design sensor technology dna nanotechnology online learning immunochemistry peptide engineering biocatalysis enzyme catalysis biliary cancer cell proliferation angiogenesis cancer growth treatment effects tumor targeting treatment development selective toxicity protein synthesis biomolecular interactions cancer treatment clinical pharmacology pharmacokinetics thixotropy chemoprevention strategies real-time sensing single chemicals aromatic rings salt bridge formation antibody-catalyzed reaction online homework software pencil-paper learning cation-p sites molecular recognition biochemistry cell transport rational drug design peptide science

Notable Scholarly Works

Notable Federal Grants

Collaborators

Small Molecule Cjoc42 Improves Chemo-Sensitivity and Increases Levels of Tumor Suppressor Proteins in Hepatoblastoma Cells and in Mice by Inhibiting Oncogene Gankyrin. Frontiers in Pharmacology (2021)

Amber M. D’SouzaAshley CastMeenasri KumbajiMaria RivasRuhi GulatiMichael JohnstonDavid SmithrudJames GellerNikolai Timchenko

medicinehepatoblastoma cellspharmacologysmall moleculespharmacokineticscancer researchliver cancerpharmacotherapyoncologyoncogene gankyrinmedicinal researchcancer treatmenttumor suppressor proteinscancer biologyclinical pharmacologytumor biologypharmacological researchcell biology

Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation. Cellular and Molecular Gastroenterology and Hepatology (2018)

Amber M. D’SouzaYanjun JiangAshley CastLeila ValanejadMary WrightKyle LewisMeenasri KumbajiSheeniza ShahDavid SmithrudRebekah KarnsSoona ShinNikolai Timchenko

metastasisbiliary cancertumor-suppressor protein degradationmolecular cancervascular biologycell proliferationcancer biologyhepatocyte proliferationdermatologycancer researchcancer growthhepatologytumor biologyimmunologycarcinogenesisangiogenesispharmacologymedicinal researchcancer cellscellular therapy

Inhibition of Gankyrin as a Therapeutic Approach for Pediatric Liver Cancer. Pediatric Blood & Cancer (2018)

pharmacologypediatric liver cancerradiation oncologycancer researchliver cancerpharmacotherapytherapeutic targetsoncologyhepatologymedicinal researchhepatocellular carcinomatherapeutic approaches

Ca2+ Selective Host Rotaxane is Highly Toxic Against Prostate Cancer Cells. Acs Medicinal Chemistry Letters (2017)

carcinogenesispharmacologyradiation oncologycancer researchanti-cancer agentsoncogenescancer cellschemoprevention strategiesprostate cancer

Ca 2+ Selective Host Rotaxane is Highly Toxic Against Prostate Cancer Cells. ACS Medicinal Chemistry Letters (2017)

David B. SmithrudLucas PowersJennifer LunnScott AbernathyMichael PeschkaShuk-mei HoPheruza Tarapore

medicinal chemistrytumor targetingmedicineenzyme inhibitionpharmacologytreatment developmentcancer researchclinical chemistrytreatment effectsurologytoxinscellular therapyanti-cancer agentsoncologytoxicologyselective toxicityprostate cancerprostate cancer cells

A Versatile Axle for the Construction of Disassemblage Rotaxanes. Molecules (2016)

Lucas PowersDavid Smithrud

materials sciencemechanical engineeringmaterials engineeringdisassemblage rotaxanesversatile axle

A Versatile Axle for the Construction of Dissasemblage Rotaxanes. Molecules (2016)

biomechanical engineeringmechanical engineeringcartilagethixotropyversatile axle

Pencil–Paper Learning Should Be Combined With Online Homework Software. Journal of Chemical Education (2015)

David B. SmithrudAllan R. Pinhas

pencil-paper learningonline learningonline homework softwarechemistryeducational technologyeducational research

Crown Ether Host-Rotaxanes as Cytotoxic Agents. ACS Medicinal Chemistry Letters (2012)

David B. SmithrudXiaoyang WangPheruza TaraporeShuk-mei Ho

medicinal chemistrycytotoxic agentspharmacology

Real-Time Sensing and Discrimination of Single Chemicals Using the Channel of Phi29 Dna Packaging Nanomotor. ACS Nano (2012)

Farzin HaqueJennifer LunnHuaming FangDavid SmithrudPeixuan Guo

sensor technologymaterials sciencenanobiotechnologydna nanotechnologyreal-time sensingsensor designsensorssingle chemicalsnanomaterialsnanotechnologynanometrologyinstrumentation

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David B. Smithrud

Associate Professor

University of Cincinnati

Affiliations

College of Arts and Sciences

Chemistry

David B. Smithrud is currently serving as a Chemistry Associate Professor at University of Cincinnati.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

David B. Smithrud

University of Cincinnati

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Amber M. D’SouzaAshley CastMeenasri KumbajiMaria RivasRuhi GulatiMichael JohnstonDavid SmithrudJames GellerNikolai Timchenko

Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation. Cellular and Molecular Gastroenterology and Hepatology (2018)

Amber M. D’SouzaYanjun JiangAshley CastLeila ValanejadMary WrightKyle LewisMeenasri KumbajiSheeniza ShahDavid SmithrudRebekah KarnsSoona ShinNikolai Timchenko

Inhibition of Gankyrin as a Therapeutic Approach for Pediatric Liver Cancer. Pediatric Blood & Cancer (2018)

pharmacologypediatric liver cancerradiation oncologycancer researchliver cancerpharmacotherapytherapeutic targetsoncologyhepatologymedicinal researchhepatocellular carcinomatherapeutic approaches

Ca2+ Selective Host Rotaxane is Highly Toxic Against Prostate Cancer Cells. Acs Medicinal Chemistry Letters (2017)

carcinogenesispharmacologyradiation oncologycancer researchanti-cancer agentsoncogenescancer cellschemoprevention strategiesprostate cancer

Ca 2+ Selective Host Rotaxane is Highly Toxic Against Prostate Cancer Cells. ACS Medicinal Chemistry Letters (2017)

David B. SmithrudLucas PowersJennifer LunnScott AbernathyMichael PeschkaShuk-mei HoPheruza Tarapore

A Versatile Axle for the Construction of Disassemblage Rotaxanes. Molecules (2016)

Lucas PowersDavid Smithrud

materials sciencemechanical engineeringmaterials engineeringdisassemblage rotaxanesversatile axle

A Versatile Axle for the Construction of Dissasemblage Rotaxanes. Molecules (2016)

biomechanical engineeringmechanical engineeringcartilagethixotropyversatile axle

Pencil–Paper Learning Should Be Combined With Online Homework Software. Journal of Chemical Education (2015)

David B. SmithrudAllan R. Pinhas

pencil-paper learningonline learningonline homework softwarechemistryeducational technologyeducational research

Crown Ether Host-Rotaxanes as Cytotoxic Agents. ACS Medicinal Chemistry Letters (2012)

David B. SmithrudXiaoyang WangPheruza TaraporeShuk-mei Ho

medicinal chemistrycytotoxic agentspharmacology

Real-Time Sensing and Discrimination of Single Chemicals Using the Channel of Phi29 Dna Packaging Nanomotor. ACS Nano (2012)

Farzin HaqueJennifer LunnHuaming FangDavid SmithrudPeixuan Guo

sensor technologymaterials sciencenanobiotechnologydna nanotechnologyreal-time sensingsensor designsensorssingle chemicalsnanomaterialsnanotechnologynanometrologyinstrumentation

1
2
3
4
5
10 / page

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Similar Faculty Members

Matthew R. Pratt

Institution

University of Southern California

glycosylation

protein science

Blake R. Peterson

Institution

Ohio State University

circular dichroism

medicinal chemistry

Paul Hergenrother

Institution

University of Illinois Urbana-Champaign

enzyme inhibitors

antibacterial compounds

Dale F. Mierke

Institution

Dartmouth College

high resolution nmr

biomolecular engineering

Gabor Tigyi

Institution

University of Tennessee Health Science Center

molecular biology

biochemistry

Ronald T. Raines

Institution

University of Wisconsin–Madison

physical organic chemistry

bioorganic chemistry

Charles E. McKenna

Institution

University of Southern California

future medicinal chemistry

medicinal chemistry

Jason Gestwicki

Institution

University of California, San Francisco

protein modeling

protein bioinformatics

David W. Christianson

Institution

University of Pennsylvania

molecular biology

enzyme catalysis

Iwao Ojima

Institution

Stony Brook University

organic chemistry

medicinal chemistry