Faculty

Institution

Unit

Venue

Rajesh Ramachandran

Associate Professor

Case Western Reserve University

Affiliations

School of Medicine

Physiology and Biophysics

Rajesh Ramachandran is currently serving as a Physiology And Biophysics Associate Professor at Case Western Reserve University.

Honors

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Experiences

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Education

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Rajesh Ramachandran

Case Western Reserve University

Associate Professor

You can click a keyword to filter the displayed items

molecular biology biophysics membrane biology structural biology cell biology protein science neuroscience protein structure mitochondrial fission structural molecular biology redox biology molecular physiology mitochondrial function cell and molecular biology gene expression molecular cell biology molecular science biomolecular structure mammalian biology liver physiology membrane proteins protein folding signal transduction biochemical sciences cellular physiology protein function protein transport molecular structure structural chemistry biological chemistry proteinlipid interaction lipid science lipoprotein metabolism conformational studies cellular biology cell physiology protein expression molecular biological method mitochondrial division cholesterol-dependent cytolysin biological macromolecules peptides mitochondrial dynamics g protein-coupled receptor receptor (biochemistry) crystal structures membrane structure molecular substrates structural bioinformatics biomolecular interactions protein chemistry colorimetry cell biomechanics inhibitory activity path dependence human sciences tissue physiology splicing variant functional modification protein evolution fragmentation effect lipid disorders protein nmr full-length murine lipid binding membrane-anchoring mechanism clathrin-mediated endocytosis b-strand alignment membrane-dependent conformational changes cholesterol-dependent cytolysin oligomerization mitochondrial membranes mitochondrial membrane fission dynamin middle domain bioenergetics defects mitochondrial fragmentation gtp-dependent conformational changes endocytic pathway molecular and cellular biology intracellular trafficking biochemistry

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Allosteric Control of Dynamin-Related Protein 1 Through a Disordered C-Terminal Short Linear Motif. Nature Communications (2024)

Isabel Pérez-JoverKristy RochonDi HuMukesh MahajanPooja Madan MohanIsaac Santos-PérezJulene Ormaetxea GisasolaJuan Manuel Martinez GalvezJon AgirreXin QiJason A MearsAnna V ShnyrovaRajesh Ramachandran

allosteric controlstructural biologyneuroscience

Structural Basis for Regulated Assembly of the Mitochondrial Fission Gtpase Drp1. Nature Communications (2024)

Kristy RochonBrianna L. BauerNathaniel A. RoethlerYuli BuckleyChih-Chia SuWei HuangRajesh RamachandranMaria S. K. StollEdward W. YuDerek J. TaylorJason A. Mears

enzymessequence assemblybiochemistryprotein assemblymolecular biologyprotein structurestructural basisstructural molecular biologystructural biologygenetics

Allosteric Control of Dynamin-Related Protein 1-Catalyzed Mitochondrial Fission Through a Conserved Disordered C-Terminal Short Linear Motif. Research Square (2023)

Isabel Pérez-JoverKristy RochonDi HuPooja Madan MohanIsaac Santos-PerezJulene Ormaetxea GisasolaJuan Manuel Martinez GalvezJon AgirreXin QiJason A. MearsAnna V. ShnyrovaRajesh Ramachandran

biophysicscatalysisallosteric controlmolecular biology

Disease-Associated Mutations in Drp1 Have Fundamentally Different Effects on the Mitochondrial Fission Machinery. Human Molecular Genetics (2023)

Brianna L BauerKristy RochonJasmine C LiuRajesh RamachandranJason A Mears

disease-associated mutationsmolecular geneticsmitochondrial fission machinerycancer geneticsmolecular biologymedical geneticsgenetics

Review of:"[Review] Structural and Functional Roles of Non-Bilayer Lipid Phase in Mitochondria". (2023)

Rajesh Ramachandran

biophysicslipidsfunctional rolesbiomolecular structurebiochemistrymolecular biologymitochondrial functionstructural biologynon-bilayer lipid phase

Conserved Pib2 Regions Have Distinct Roles in Torc1 Regulation at the Vacuole. Journal of Cell Science (2022)

Kayla K. TroutmanNatalia V. VarlakhanovaBryan A. TornabeneRajesh RamachandranMarijn G. J. Ford

regulationcell physiologyphysiologycell signalingcell biologycellular physiologymembrane biologymolecular cell biologymolecular regulationmolecular biologycellular biologycell regulationcellular biochemistrydistinct rolesconservation biologycell and molecular biology

Drp1 and the Cytoskeleton: Mechanistic Nexus in Mitochondrial Division. Current Opinion in Physiology (2022)

Jason A MearsRajesh Ramachandran

biophysicsphysiologymechanistic nexushuman biologyneurophysiologycytoskeletonmolecular biologymitochondrial divisionhuman physiology

Evidence for Novel Phosphorylation Sites in the Central C4-C5 Domains of Murine Cardiac Myosin Binding Protein C. Biophysical Journal (2022)

Chang Yoon DohKatherine L. DominicCaitlin E. SwanbergNikhil BharambeLing LiBelinda WillardRajesh RamachandranJulian E. Stelzer

biophysicscardiologyprotein phosphorylationprotein sciencebiophysical reviewprotein functionnovel phosphorylation sitesneurosciencebiochemistrymolecular biophysicsmolecular physiologyexperimental biophysicscardiac musclebiophysical modelingprotein structuremurine cardiac myosinbiophysical chemistrystructural biology

Identification of Phosphorylation and Other Post-Translational Modifications in the Central C4C5 Domains of Murine Cardiac Myosin Binding Protein C. ACS Omega (2022)

Chang Yoon DohKatherine L. DominicCaitlin E. SwanbergNikhil BharambeBelinda B. WillardLing LiRajesh RamachandranJulian E. Stelzer

protein expressionprotein phosphorylationprotein sciencecell signalingcell biologyprotein functionmurine cardiac myosinbiochemistrycardiac musclemolecular physiologymembrane biologysignal transductiongene expressionstructural biologygenetics

Light Scattering Techniques to Assess Self-Assembly and Hydrodynamics of Membrane Trafficking Proteins. Methods in molecular biology (2022)

Marijn G. J. FordRajesh Ramachandran

biophysicsbiological engineeringprotein sciencelight scatteringmembrane trafficking proteinsmolecular biologystructural biology

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Rajesh Ramachandran

Associate Professor

Case Western Reserve University

Affiliations

School of Medicine

Physiology and Biophysics

Rajesh Ramachandran is currently serving as a Physiology And Biophysics Associate Professor at Case Western Reserve University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Rajesh Ramachandran

Case Western Reserve University

Associate Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Allosteric Control of Dynamin-Related Protein 1 Through a Disordered C-Terminal Short Linear Motif. Nature Communications (2024)

allosteric controlstructural biologyneuroscience

Structural Basis for Regulated Assembly of the Mitochondrial Fission Gtpase Drp1. Nature Communications (2024)

Kristy RochonBrianna L. BauerNathaniel A. RoethlerYuli BuckleyChih-Chia SuWei HuangRajesh RamachandranMaria S. K. StollEdward W. YuDerek J. TaylorJason A. Mears

enzymessequence assemblybiochemistryprotein assemblymolecular biologyprotein structurestructural basisstructural molecular biologystructural biologygenetics

Allosteric Control of Dynamin-Related Protein 1-Catalyzed Mitochondrial Fission Through a Conserved Disordered C-Terminal Short Linear Motif. Research Square (2023)

Isabel Pérez-JoverKristy RochonDi HuPooja Madan MohanIsaac Santos-PerezJulene Ormaetxea GisasolaJuan Manuel Martinez GalvezJon AgirreXin QiJason A. MearsAnna V. ShnyrovaRajesh Ramachandran

biophysicscatalysisallosteric controlmolecular biology

Disease-Associated Mutations in Drp1 Have Fundamentally Different Effects on the Mitochondrial Fission Machinery. Human Molecular Genetics (2023)

Brianna L BauerKristy RochonJasmine C LiuRajesh RamachandranJason A Mears

disease-associated mutationsmolecular geneticsmitochondrial fission machinerycancer geneticsmolecular biologymedical geneticsgenetics

Review of:"[Review] Structural and Functional Roles of Non-Bilayer Lipid Phase in Mitochondria". (2023)

Rajesh Ramachandran

biophysicslipidsfunctional rolesbiomolecular structurebiochemistrymolecular biologymitochondrial functionstructural biologynon-bilayer lipid phase

Conserved Pib2 Regions Have Distinct Roles in Torc1 Regulation at the Vacuole. Journal of Cell Science (2022)

Kayla K. TroutmanNatalia V. VarlakhanovaBryan A. TornabeneRajesh RamachandranMarijn G. J. Ford

Drp1 and the Cytoskeleton: Mechanistic Nexus in Mitochondrial Division. Current Opinion in Physiology (2022)

Jason A MearsRajesh Ramachandran

biophysicsphysiologymechanistic nexushuman biologyneurophysiologycytoskeletonmolecular biologymitochondrial divisionhuman physiology

Evidence for Novel Phosphorylation Sites in the Central C4-C5 Domains of Murine Cardiac Myosin Binding Protein C. Biophysical Journal (2022)

Chang Yoon DohKatherine L. DominicCaitlin E. SwanbergNikhil BharambeLing LiBelinda WillardRajesh RamachandranJulian E. Stelzer

Identification of Phosphorylation and Other Post-Translational Modifications in the Central C4C5 Domains of Murine Cardiac Myosin Binding Protein C. ACS Omega (2022)

Chang Yoon DohKatherine L. DominicCaitlin E. SwanbergNikhil BharambeBelinda B. WillardLing LiRajesh RamachandranJulian E. Stelzer

Light Scattering Techniques to Assess Self-Assembly and Hydrodynamics of Membrane Trafficking Proteins. Methods in molecular biology (2022)

Marijn G. J. FordRajesh Ramachandran

biophysicsbiological engineeringprotein sciencelight scatteringmembrane trafficking proteinsmolecular biologystructural biology

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