Faculty

Institution

Unit

Venue

Christopher Yengo

Professor

Pennsylvania State University

Affiliations

Penn State College of Medicine

Department of Biochemistry & Molecular Biology

Department of Cellular & Molecular Physiology

Department of Medicine

Department of Neural and Behavioral Sciences

Department of Neurosurgery

Department of Pathology and Laboratory Medicine

Department of Pediatrics

Department of Pharmacology

Department of Public Health Sciences

Department of Radiation Oncology

Department of Radiology

Department of Surgery

Department of Public Health Sciences

Division of Biostatistics and Bioinformatics

Department of Pathology and Laboratory Medicine

Division of Clinical Pathology

Division of Experimental Pathology

Department of Pediatrics

Division of Critical Care Medicine

Department of Medicine

Division of Gastroenterology and Hepatology

Division of Hematology and Oncology

Department of Surgery

Division of Plastic Surgery

Division of Thoracic Surgery

Christopher Yengo is currently serving as a Biochemistry & Molecular Biology Professor at Pennsylvania State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Christopher Yengo

Pennsylvania State University

Professor

You can click a keyword to filter the displayed items

biophysics protein science cell biology molecular biology cardiology molecular biophysics structural biology membrane biology biochemistry cellular physiology experimental biophysics mammalian biology molecular physiology cardiomyopathy gene expression protein structure medical biophysics biomechanics biological chemistry cell and molecular biology vascular biology cardiac muscle applied physiology human physiology cardiovascular physiology cardiovascular research cell motility muscle function skeletal muscle structural molecular biology molecular regulation cellular biochemistry liver physiology protein function protein transport cell biomechanics physiological research biomolecular interactions actin protrusions biochemical sciences redox biology cellular biology intracellular trafficking mechanotransduction cellular structure in vivo systems smooth muscle myosin clinical biochemistry molecular cell biology circulatory physiology immunosuppression integrative biology mutagenesis cell regulation molecular neurobiology physiological regulation chronic ankle instability tick saliva immunosuppressor kinetic mechanism hair cells functional role conformational changes class iii myosins motor drives cell trafficking orthopedic biomechanics receptor (biochemistry) mucosal immunology medical microbiology structural state directionality reversal myosin vi motor actin filaments myosin iiia sensorimotor function blebbistatin inhibition cytoskeleton myosin motors

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2025 - a Critical Salt Bridge Between the Relay Helix and Activation Loop in Beta-Cardiac Myosin Coordinates Actin Activation of the Power Stroke and Phosphate Release. Biophysical Journal (2025)

Skylar M.L. BodtWen MaChristopher M. Yengo

biophysicsbeta-cardiac myosin coordinatesrelay helixpower strokebiophysical modelingphosphate releaseactivation loopbiophysical chemistry

Bps2025 - Cardiac Myosin 25-Hep E525K Mutated Construct With Mavacamten is Stabilized by Three Blocked Head Subfragment-2 Interactions. Biophysical Journal (2025)

Ruchi SharmaJinghua GeChristopher M. YengoRoger CraigRaul Padron

biophysicsbiophysical aspectbiophysical modelingbiomedical engineeringvascular biologymechanotransductionmolecular biologyexperimental biophysicsbiophysical chemistrybiophysical reviewcardiac muscle

Bps2025 - Differential Modulation of Beta-Cardiac Myosin Conformations by Cardiomyopathy-Associated Mutations in the Converter Domain. Biophysical Journal (2025)

Jinghua GeSebastian Duno-MirandaArun Kumar SomavarapuSkylar M.L. BodtRuchi Gautam SharmaSamantha Beck PrevisAngela PloysangngamRoger CraigRaul PadronDavid M. WarshawChristopher M. Yengo

biophysicsbiophysical modelingcardiomyopathy-associated mutationsconverter domaindifferential modulationbeta-cardiac myosin conformationsbiophysical chemistrybiophysical review

Bps2025 - Impact of Magnesium and Ionic Strength Reveals a Role of Crucial Salt Bridge in the Motor Domain of Human Cardiac Myosin Abolished by the E525K Mutation. Biophysical Journal (2025)

Jinghua GeMichael R. EbertSkylar M.L. BodtChristopher M. Yengo

biophysicshuman cardiac myosincrucial salt bridgemotor domainmolecular motorsionic strengthbiophysical reviewcardiac muscle

Bps2025 - Mavacamten and Omecamtiv Mecarbil Modulate the Structure of the Interacting-Heads Motif by Inducing Distinct Subfragment-2 Conformations. Biophysical Journal (2025)

Arun Kumar SomavarapuJinghua GeChristopher M. YengoRaul PadronRoger Craig

biophysicsbiophysical modelingbiophysical chemistryinteracting-heads motifbiophysical review

A Single-Molecule Characterization of Load-Dependent Phosphate Rebinding to Myosin Va. Biophysical Journal (2024)

Christopher MarangBrent ScottLaura K. GuntherChristopher M. YengoEdward P. Debold

biophysicsprotein sciencemolecular biophysicsneurosciencebiomedical engineeringsingle-molecule characterizationload-dependent phosphate rebinding

Cardiomyopathy-Associated Mutations in the Converter Domain of Beta-Cardiac Myosin Differentially Alter Formation of the Super Relaxed State and Interacting Heads Motif. Biophysical Journal (2024)

Jinghua GeSebastian Duno-MirandaSkylar M.L. BodtDavid M. WarshawChristopher M. Yengo

biophysicscardiomyopathybeta-cardiac myosingeneticscardiologycardiomyopathy-associated mutationsmolecular biophysicsconverter domainmolecular biologyalter formationheads motif

Dilated Cardiomyopathy Mutation in Beta-Cardiac Myosin Enhances Actin Activation of the Power Stroke and Phosphate Release. PNAS Nexus (2024)

Skylar M L BodtJinghua GeWen MaDavid V RasicciRohini DesettyJ Andrew McCammonChristopher M Yengo

cardiomyopathygeneticspower strokecardiologycardiomyopathy mutationphosphate releasepharmacology

Impact of Chronic Alcohol Consumption on Cardiac Myosin Function: Role of Oxidative Stress. Biophysical Journal (2024)

Adrien P. ChenDavid V. RasicciJinghua GeNeil WoodSkylar M.L. BodtOmid GolestanianMd Shahrier AminAnne PruznakMichael J. PrevisCharles H. LangChristopher M. Yengo

biophysicschronic alcohol consumptionoxidative stresscardiologycardiovascular physiologycardiac myosin functionneurosciencebioenergeticsmedical biophysicsphysiologyalcohol dependencecardiovascular researchcardiovascular disease

Myosin-Dependent Short Actin Filaments Contribute to Peripheral Widening in Developing Stereocilia. Research Square (Research Square) (2024)

Benjamin PerrinXiayi LiaoChun-Yu TungJocelyn KreyGhazaleh BehnammaneshJoseph CiriloMert ColpanChristopher YengoPeter Barr-GillespieJonathan Bird

developmental biologycytoskeletonmorphogenesiscellular differentiationstem cellscell biologymembrane biologyvascular biologycell researchintracellular traffickingperipheral wideningmolecular biology

1
2
3
4
5
13
10 / page

Christopher Yengo

Professor

Pennsylvania State University

Affiliations

Penn State College of Medicine

Department of Biochemistry & Molecular Biology

Department of Cellular & Molecular Physiology

Department of Medicine

Department of Neural and Behavioral Sciences

Department of Neurosurgery

Department of Pathology and Laboratory Medicine

Department of Pediatrics

Department of Pharmacology

Department of Public Health Sciences

Department of Radiation Oncology

Department of Radiology

Department of Surgery

Department of Public Health Sciences

Division of Biostatistics and Bioinformatics

Department of Pathology and Laboratory Medicine

Division of Clinical Pathology

Division of Experimental Pathology

Department of Pediatrics

Division of Critical Care Medicine

Department of Medicine

Division of Gastroenterology and Hepatology

Division of Hematology and Oncology

Department of Surgery

Division of Plastic Surgery

Division of Thoracic Surgery

Christopher Yengo is currently serving as a Biochemistry & Molecular Biology Professor at Pennsylvania State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Christopher Yengo

Pennsylvania State University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Skylar M.L. BodtWen MaChristopher M. Yengo

biophysicsbeta-cardiac myosin coordinatesrelay helixpower strokebiophysical modelingphosphate releaseactivation loopbiophysical chemistry

Bps2025 - Cardiac Myosin 25-Hep E525K Mutated Construct With Mavacamten is Stabilized by Three Blocked Head Subfragment-2 Interactions. Biophysical Journal (2025)

Ruchi SharmaJinghua GeChristopher M. YengoRoger CraigRaul Padron

biophysicsbiophysical aspectbiophysical modelingbiomedical engineeringvascular biologymechanotransductionmolecular biologyexperimental biophysicsbiophysical chemistrybiophysical reviewcardiac muscle

Bps2025 - Differential Modulation of Beta-Cardiac Myosin Conformations by Cardiomyopathy-Associated Mutations in the Converter Domain. Biophysical Journal (2025)

Jinghua GeSebastian Duno-MirandaArun Kumar SomavarapuSkylar M.L. BodtRuchi Gautam SharmaSamantha Beck PrevisAngela PloysangngamRoger CraigRaul PadronDavid M. WarshawChristopher M. Yengo

biophysicsbiophysical modelingcardiomyopathy-associated mutationsconverter domaindifferential modulationbeta-cardiac myosin conformationsbiophysical chemistrybiophysical review

Bps2025 - Impact of Magnesium and Ionic Strength Reveals a Role of Crucial Salt Bridge in the Motor Domain of Human Cardiac Myosin Abolished by the E525K Mutation. Biophysical Journal (2025)

Jinghua GeMichael R. EbertSkylar M.L. BodtChristopher M. Yengo

biophysicshuman cardiac myosincrucial salt bridgemotor domainmolecular motorsionic strengthbiophysical reviewcardiac muscle

Bps2025 - Mavacamten and Omecamtiv Mecarbil Modulate the Structure of the Interacting-Heads Motif by Inducing Distinct Subfragment-2 Conformations. Biophysical Journal (2025)

Arun Kumar SomavarapuJinghua GeChristopher M. YengoRaul PadronRoger Craig

biophysicsbiophysical modelingbiophysical chemistryinteracting-heads motifbiophysical review

A Single-Molecule Characterization of Load-Dependent Phosphate Rebinding to Myosin Va. Biophysical Journal (2024)

Christopher MarangBrent ScottLaura K. GuntherChristopher M. YengoEdward P. Debold

biophysicsprotein sciencemolecular biophysicsneurosciencebiomedical engineeringsingle-molecule characterizationload-dependent phosphate rebinding

Cardiomyopathy-Associated Mutations in the Converter Domain of Beta-Cardiac Myosin Differentially Alter Formation of the Super Relaxed State and Interacting Heads Motif. Biophysical Journal (2024)

Jinghua GeSebastian Duno-MirandaSkylar M.L. BodtDavid M. WarshawChristopher M. Yengo

biophysicscardiomyopathybeta-cardiac myosingeneticscardiologycardiomyopathy-associated mutationsmolecular biophysicsconverter domainmolecular biologyalter formationheads motif

Dilated Cardiomyopathy Mutation in Beta-Cardiac Myosin Enhances Actin Activation of the Power Stroke and Phosphate Release. PNAS Nexus (2024)

Skylar M L BodtJinghua GeWen MaDavid V RasicciRohini DesettyJ Andrew McCammonChristopher M Yengo

cardiomyopathygeneticspower strokecardiologycardiomyopathy mutationphosphate releasepharmacology

Impact of Chronic Alcohol Consumption on Cardiac Myosin Function: Role of Oxidative Stress. Biophysical Journal (2024)

Adrien P. ChenDavid V. RasicciJinghua GeNeil WoodSkylar M.L. BodtOmid GolestanianMd Shahrier AminAnne PruznakMichael J. PrevisCharles H. LangChristopher M. Yengo

Myosin-Dependent Short Actin Filaments Contribute to Peripheral Widening in Developing Stereocilia. Research Square (Research Square) (2024)

Benjamin PerrinXiayi LiaoChun-Yu TungJocelyn KreyGhazaleh BehnammaneshJoseph CiriloMert ColpanChristopher YengoPeter Barr-GillespieJonathan Bird

developmental biologycytoskeletonmorphogenesiscellular differentiationstem cellscell biologymembrane biologyvascular biologycell researchintracellular traffickingperipheral wideningmolecular biology

1
2
3
4
5
13
10 / page

Similar Faculty Members

Jian-Ping Jin

Institution

University of Illinois Chicago

developmental biology

muscle cell motility

Danuta Szczesna-Cordary

Institution

University of Miami

cardiac muscle

molecular cell biology

Kenneth S. Campbell

Institution

University of Kentucky

physiology

cardiology

Aldrin V. Gomes

Institution

University of California, Davis

protein homeostasis

metabolism

Jack Kaplan

Institution

University of Illinois Chicago

molecular biology

membrane protein

Carol C. Gregorio

Institution

University of Arizona

cardiac muscle

cellular physiology

Matthew J. Tyska

Institution

Vanderbilt University

physiological homeostasis

molecular and cellular biology

David F. Wieczorek

Institution

University of Cincinnati

cardiac muscle

developmental biology

Nipavan Chiamvimonvat

Institution

University of Arizona

circulatory physiology

electrophysiology

R John Solaro

Institution

University of Illinois Chicago

electrophysiology

cellular physiology

Similar Faculty Members

Jian-Ping Jin

Institution

University of Illinois Chicago

developmental biology

muscle cell motility

Danuta Szczesna-Cordary

Institution

University of Miami

cardiac muscle

molecular cell biology

Kenneth S. Campbell

Institution

University of Kentucky

physiology

cardiology

Aldrin V. Gomes

Institution

University of California, Davis

protein homeostasis

metabolism

Jack Kaplan

Institution

University of Illinois Chicago

molecular biology

membrane protein

Carol C. Gregorio

Institution

University of Arizona

cardiac muscle

cellular physiology

Matthew J. Tyska

Institution

Vanderbilt University

physiological homeostasis

molecular and cellular biology

David F. Wieczorek

Institution

University of Cincinnati

cardiac muscle

developmental biology

Nipavan Chiamvimonvat

Institution

University of Arizona

circulatory physiology

electrophysiology

R John Solaro

Institution

University of Illinois Chicago

electrophysiology

cellular physiology