Faculty

Institution

Unit

Venue

Patrick Reardon

NMR Facility Director

Oregon State University

Affiliations

College of Science

Department of Biochemistry and Biophysics

Department of Statistics

Patrick Reardon is the NMR Facility Director in the Department of Biochemistry & Biophysics at Oregon State University. He earned his Ph.D. in Biochemistry from Duke University in 2011 and completed postdoctoral research at the Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory. His research applies nuclear magnetic resonance spectroscopy to structural biology, focusing on intrinsically disordered proteins, membrane-associated ferlin C2 domains, and phase separation in SARS-CoV-2 nucleocapsid proteins. Recent work includes studies on Hsp90 nitration, LC8-mediated 53BP1 oligomerization, and kombucha microbial community dynamics. He received a 2023 NSF MRI award for helium recovery equipment and collaborates with institutions across North America, Europe, Asia, and Australia.

Honors

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Patrick Reardon

Oregon State University

NMR Facility Director

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molecular biology structural biology protein science biophysics genetics protein structure gene expression membrane biology nuclear magnetic resonance virus research structural molecular biology biomolecular structure viral genetics sars-cov-2 biological chemistry biomolecular interactions materials science virology molecular genetics molecular science molecular virology rna biology general virology nucleic acids genome biology viral structural protein molecular physiology virus-host interactions nuclear magnetic resonance spectroscopy molecular regulation protein function protein phosphorylation avian biology cheminformatics virus structure epigenomics interactomics protein synthesis biochemical genetics protein genetics multivalent binding autonomous synthesis cataract-associated deamidations experimental gerontology mammalian biology animal science insect molecular biology electrode-electrolyte interfaces biological inorganic chemistry structural composition nanofibers biogerontology rational drug design rna processing antibody engineering antiviral therapy gene expression profiling dna analysis molecular recognition laparoscopy gene regulation transcription regulation rna structure prediction geobacter sulfurreducens conductive bacterial nanowires monoclonal antibody therapeutics lactate dehydrogenase expression drosophila melanogaster paralog-specific drug design automated framework increased aggregation human gs-crystallin protein dynamics metj repressor interactions in-cell nmr wet flue gas biophysical chemistry molecular biophysics molecular structure structural bioinformatics

Notable Scholarly Works

Notable Federal Grants

Collaborators

Author Response: Lc8 Enhances 53Bp1 Foci Through Heterogeneous Bridging of 53Bp1 Oligomers. (2025)

author responsebiological macromoleculesprotein assemblyprotein structuremolecular structurebiomolecular structureheterogeneous bridgingmolecular biologystructural molecular biologystructural biologybiochemistrynucleic acids

Changes in Microbial Community Structure During Adaptation of Kombucha Symbiotic Culture of Bacteria and Yeast to Fermentation of Sweet and Acid Whey. Journal of Dairy Science (2025)

microbiomesymbiotic culturemicrobial diversitybiological engineeringfood fermentationapplied microbiologymicrobial community structureenvironmental microbiologymicrobial ecologymicroorganismsacid wheybacteriafood microbiologymicrobiology

Disordered Ferlin C2A–C2B Linkers Bind Membranes and Encode Small Linear Motifs. Journal of Molecular Biology (2025)

biomolecular interactionsmolecular scienceprotein structuremolecular structurebiomolecular structurebiomolecular engineeringmolecular biologymembrane proteinsstructural chemistrystructural molecular biologymembrane structurestructural biology

Ferlin C2A-C2B Linkers Are Alternatively Spliced, Intrinsically Disordered, and Interact With Negatively Charged Membranes. bioRxiv (Cold Spring Harbor Laboratory) (2025)

biophysicsmembranesmembrane systemsmolecular sciencemolecular structureferlin c2a-c2b linkersmolecular biologymembrane proteinsmembrane sciencemembrane structuremembrane biology

Lc8 Enhances 53Bp1 Foci Through Heterogeneous Bridging of 53Bp1 Oligomers. eLife (2025)

molecular scienceprotein structuremolecular structurebiomolecular structureheterogeneous bridgingmolecular biologystructural molecular biologybiochemistrystructural biologychemical structure

Nitration-Driven Structural Changes in Hsp90 Linked to Gain of Pathological Functions. Biochemical Journal (2025)

protein functionpathological functionsprotein structureproteome researchnitration-driven structural changesmolecular biologymolecular basisbiochemistrystructural biologyprotein scienceprotein folding

Dna-Based Assay for Calorimetric Determination of Protein Concentrations in Pure or Mixed Solutions. PLoS ONE (2024)

Matthew W. EskewPatrick ReardonAlbert S. Benight

proteomicsmixed solutionsdna-based assayprotein concentrationsplo biologygeneticsmolecular biologycalorimetric determination

Lc8 Enhances 53Bp1 Foci Through Heterogeneous Bridging of 53Bp1 Oligomers. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jesse HoweDouglas WalkerKyle TenglerMaya SonpatkiPatrick N ReardonJustin W.C. LeungElisar J Barbar

biophysicsprotein assemblyself-assemblyheterogeneous bridgingmolecular biologyprotein sciencelarge scale structurebiochemistry

Phosphorylation in the Ser/Arg-Rich Region of the Nucleocapsid of Sars-Cov-2 Regulates Phase Separation by Inhibiting Self-Association of a Distant Helix. Journal of Biological Chemistry (2024)

Hannah StuwePatrick N. ReardonZhen YuSahana ShahKaitlyn HughesElisar J. Barbar

virus researchgene expressionsars-cov-2geneticsmolecular and cellular biologyviral geneticsprotein phosphorylationdistant helixmolecular biologybiological chemistrycell and molecular biologystructural molecular biologystructural biologyviral structural proteinprotein sciencemolecular physiologybiochemistry

Abstract 1826: Accessing Isotopically Labeled Proteins Containing Genetically Encoded Phosphoserine for Nmr With Optimized Expression Conditions. Journal of Biological Chemistry (2023)

Cat VeselyPatrick ReardonZhen YuElisar BarbarRyan MehlRichard Cooley

medicinal chemistrygene expressionpharmacologymolecular biologybiological chemistryprotein expressionnuclear magnetic resonanceprotein scienceprotein engineeringbiological engineering

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Patrick Reardon

NMR Facility Director

Oregon State University

Affiliations

College of Science

Department of Biochemistry and Biophysics

Department of Statistics

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Patrick Reardon

Oregon State University

NMR Facility Director

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Author Response: Lc8 Enhances 53Bp1 Foci Through Heterogeneous Bridging of 53Bp1 Oligomers. (2025)

Changes in Microbial Community Structure During Adaptation of Kombucha Symbiotic Culture of Bacteria and Yeast to Fermentation of Sweet and Acid Whey. Journal of Dairy Science (2025)

Disordered Ferlin C2A–C2B Linkers Bind Membranes and Encode Small Linear Motifs. Journal of Molecular Biology (2025)

Ferlin C2A-C2B Linkers Are Alternatively Spliced, Intrinsically Disordered, and Interact With Negatively Charged Membranes. bioRxiv (Cold Spring Harbor Laboratory) (2025)

biophysicsmembranesmembrane systemsmolecular sciencemolecular structureferlin c2a-c2b linkersmolecular biologymembrane proteinsmembrane sciencemembrane structuremembrane biology

Lc8 Enhances 53Bp1 Foci Through Heterogeneous Bridging of 53Bp1 Oligomers. eLife (2025)

molecular scienceprotein structuremolecular structurebiomolecular structureheterogeneous bridgingmolecular biologystructural molecular biologybiochemistrystructural biologychemical structure

Nitration-Driven Structural Changes in Hsp90 Linked to Gain of Pathological Functions. Biochemical Journal (2025)

protein functionpathological functionsprotein structureproteome researchnitration-driven structural changesmolecular biologymolecular basisbiochemistrystructural biologyprotein scienceprotein folding

Dna-Based Assay for Calorimetric Determination of Protein Concentrations in Pure or Mixed Solutions. PLoS ONE (2024)

Matthew W. EskewPatrick ReardonAlbert S. Benight

proteomicsmixed solutionsdna-based assayprotein concentrationsplo biologygeneticsmolecular biologycalorimetric determination

Lc8 Enhances 53Bp1 Foci Through Heterogeneous Bridging of 53Bp1 Oligomers. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jesse HoweDouglas WalkerKyle TenglerMaya SonpatkiPatrick N ReardonJustin W.C. LeungElisar J Barbar

biophysicsprotein assemblyself-assemblyheterogeneous bridgingmolecular biologyprotein sciencelarge scale structurebiochemistry

Phosphorylation in the Ser/Arg-Rich Region of the Nucleocapsid of Sars-Cov-2 Regulates Phase Separation by Inhibiting Self-Association of a Distant Helix. Journal of Biological Chemistry (2024)

Hannah StuwePatrick N. ReardonZhen YuSahana ShahKaitlyn HughesElisar J. Barbar

Abstract 1826: Accessing Isotopically Labeled Proteins Containing Genetically Encoded Phosphoserine for Nmr With Optimized Expression Conditions. Journal of Biological Chemistry (2023)

Cat VeselyPatrick ReardonZhen YuElisar BarbarRyan MehlRichard Cooley

medicinal chemistrygene expressionpharmacologymolecular biologybiological chemistryprotein expressionnuclear magnetic resonanceprotein scienceprotein engineeringbiological engineering

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