Faculty

Institution

Unit

Venue

Oksana Lockridge

Professor

University of Nebraska Medical Center

Affiliations

Eppley Institute for Research in Cancer and Allied Fields

Oksana Lockridge is currently serving as an Eppley Institute For Research In Cancer And Allied Fields Professor at University of Nebraska Medical Center.

Honors

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Experiences

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Education

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Oksana Lockridge

University of Nebraska Medical Center

Professor

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biochemistry molecular biology enzymes biomolecular engineering protein science enzyme inhibition pharmacology chemical biology toxicology human butyrylcholinesterase structural molecular biology peptide science peptides protein structure medicinal research medicinal chemistry redox biology mass spectrometry biochemical engineering structural biology inhibitory activity enzymatic modification knockout mice neurochemistry protein chemistry enzyme catalysis biochemical interaction analytical toxicology structure-function enzyme kinetics biomolecular structure biochemical sciences transition metal chemistry biomolecular interactions protein phosphorylation protein mass spectrometry molecular neurodegeneration molecular metabolism molecular neurobiology catalyst activation enzyme specificity protein biosynthesis pharmacological research vascular biology mammalian biology secondary metabolites cellular enzymology proteinlipid interaction functional selectivity selective toxicity key site experimental pharmacology molecular evidence toxicological mechanism biological function biocatalysis experimental toxicology molecular substrates clinical pharmacology human polymorphisms functional modification chemical safety human plasma genetic variants acetylcholinesterase knockout mouse acetylcholinesterase-deficient mice human albumin butyrylcholinesterase knockout mouse human acetylcholinesterase chlorpyrifos oxon human serum cholinesterase aerotoxic syndrome cresyl saligenin phosphate organophosphorus toxicants human serum albumin monoclonal antibodies organophosphorus poisons protein purification

Notable Scholarly Works

Notable Federal Grants

Collaborators

Francisella Tularensis Universal Stress Protein Contributes to Persistence During Growth Arrest and Paraquat-Induced Superoxide Stress. Journal of Bacteriology (2025)

Benjamin GirardoYinshi YueOksana LockridgeAmanda M. BartlingLawrence M. SchopferLeonardo AugustoMarilynn A. Larson

paraquat-induced superoxide stressgrowth arrestmicrobiologybacteriabacteriology

Mass Spectrometry of Putrescine, Spermidine, and Spermine Covalently Attached to Francisella Tularensis Universal Stress Protein and Bovine Albumin. Biochemistry Research International (2024)

Lawrence M. SchopferBenjamin GirardoOksana LockridgeMarilynn A. Larson

bovine albuminmass spectrometrybiochemistry

Pharmacokinetics and Fate of Free and Encapsulated Ird800Cw-Labelled Human Bche Intravenously Administered in Mice. International Journal of Biological Macromolecules (2024)

Tatiana PashirovaZukhra ShaihutdinovaDmitry TatarinovAngelina TitovaAlbina MalanyevaOlga VasilevaKamil GabdurakhmanovSergei DudnikovLawrence M SchopferOksana LockridgePatrick Masson

pharmacokineticsbiological macromoleculesbiochemistry

Polyaminated, Acetylated and Stop Codon Readthrough of Recombinant Francisella Tularensis Universal Stress Protein in Escherichia Coli. PLoS ONE (2024)

Benjamin GirardoLawrence M SchopferYinshi YueOksana LockridgeMarilynn A Larson

clinical microbiologymolecular microbiologymicrobiologymolecular biologyescherichia colimicrobial pathogenesis

Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-Linking. Chemical Research in Toxicology (2023)

Diego Muñoz-TorreroLawrence M. SchopferOksana Lockridge

toxicologyprotein cross-linking

Drug and Pro-Drug Substrates and Pseudo-Substrates of Human Butyrylcholinesterase. Biochemical Pharmacology (2023)

Patrick MassonZukhra ShaihutdinovaOksana Lockridge

bioactive compoundspharmacologytherapeutic targetsclinical pharmacologypharmaceutical chemistryhuman butyrylcholinesterasedrug metabolismdrug discoverypharmacotherapymedicinal researchbiochemistrymedicinal chemistrypro-drug substratesremedial actionpeptide sciencefunctional selectivitymolecular substratespharmacological researchenzyme inhibitionbiomolecular engineering

Esterases. Elsevier eBooks (2023)

Oksana LockridgeDaniel M QuinnZoran Radić

Human Butyrylcholinesterase in Cohn Fraction IV-4 Purified in a Single Chromatography Step on Hupresin. PLoS ONE (2023)

Lawrence M. SchopferEmilie DavidSteven H. HinrichsOksana Lockridge

single chromatography stephuman butyrylcholinesterasedrug analysisanalytical chemistrychromatographybiochemistrycohn fraction

Overview of Adductomics in Toxicology. Current Protocols (2023)

Oksana Lockridge

toxicologyexperimental toxicology

REVIEW: Organophosphorus Toxicants, in Addition to Inhibiting Acetylcholinesterase Activity, Make Covalent Adducts on Multiple Proteins and Promote Protein Crosslinking Into High Molecular Weight Aggregates. Chemico-Biological Interactions (2023)

Oksana LockridgeLawrence M. Schopfer

natural productscovalent adductsmultiple proteinspharmacologystructural molecular biologypeptideschemical biologyinhibitory activitybiochemical engineeringselective toxicitybiochemistrymedicinal chemistryprotein structureacetylcholinesterase activityproteinlipid interactionprotein scienceprotein chemistrypeptide scienceorganophosphorus toxicantscatalyst activationenzyme inhibitionbiomolecular engineering

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Oksana Lockridge

Professor

University of Nebraska Medical Center

Affiliations

Eppley Institute for Research in Cancer and Allied Fields

Oksana Lockridge is currently serving as an Eppley Institute For Research In Cancer And Allied Fields Professor at University of Nebraska Medical Center.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Oksana Lockridge

University of Nebraska Medical Center

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Francisella Tularensis Universal Stress Protein Contributes to Persistence During Growth Arrest and Paraquat-Induced Superoxide Stress. Journal of Bacteriology (2025)

Benjamin GirardoYinshi YueOksana LockridgeAmanda M. BartlingLawrence M. SchopferLeonardo AugustoMarilynn A. Larson

paraquat-induced superoxide stressgrowth arrestmicrobiologybacteriabacteriology

Mass Spectrometry of Putrescine, Spermidine, and Spermine Covalently Attached to Francisella Tularensis Universal Stress Protein and Bovine Albumin. Biochemistry Research International (2024)

Lawrence M. SchopferBenjamin GirardoOksana LockridgeMarilynn A. Larson

bovine albuminmass spectrometrybiochemistry

Pharmacokinetics and Fate of Free and Encapsulated Ird800Cw-Labelled Human Bche Intravenously Administered in Mice. International Journal of Biological Macromolecules (2024)

Tatiana PashirovaZukhra ShaihutdinovaDmitry TatarinovAngelina TitovaAlbina MalanyevaOlga VasilevaKamil GabdurakhmanovSergei DudnikovLawrence M SchopferOksana LockridgePatrick Masson

pharmacokineticsbiological macromoleculesbiochemistry

Polyaminated, Acetylated and Stop Codon Readthrough of Recombinant Francisella Tularensis Universal Stress Protein in Escherichia Coli. PLoS ONE (2024)

Benjamin GirardoLawrence M SchopferYinshi YueOksana LockridgeMarilynn A Larson

clinical microbiologymolecular microbiologymicrobiologymolecular biologyescherichia colimicrobial pathogenesis

Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-Linking. Chemical Research in Toxicology (2023)

Diego Muñoz-TorreroLawrence M. SchopferOksana Lockridge

toxicologyprotein cross-linking

Drug and Pro-Drug Substrates and Pseudo-Substrates of Human Butyrylcholinesterase. Biochemical Pharmacology (2023)

Patrick MassonZukhra ShaihutdinovaOksana Lockridge

Esterases. Elsevier eBooks (2023)

Oksana LockridgeDaniel M QuinnZoran Radić

Human Butyrylcholinesterase in Cohn Fraction IV-4 Purified in a Single Chromatography Step on Hupresin. PLoS ONE (2023)

Lawrence M. SchopferEmilie DavidSteven H. HinrichsOksana Lockridge

single chromatography stephuman butyrylcholinesterasedrug analysisanalytical chemistrychromatographybiochemistrycohn fraction

Overview of Adductomics in Toxicology. Current Protocols (2023)

Oksana Lockridge

toxicologyexperimental toxicology

Oksana LockridgeLawrence M. Schopfer

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protein modeling

protein structure

Robert J. Fletterick

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Carol Fierke

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