Faculty

Institution

Unit

Venue

Nicholas Farrell

Emeritus

Virginia Commonwealth University

Affiliations

College of Humanities and Sciences

Department of Chemistry

Nicholas Farrell is currently serving as a College Of Humanities And Sciences Emeritus at Virginia Commonwealth University.

Honors

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Experiences

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Education

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Nicholas Farrell

Virginia Commonwealth University

Emeritus

You can click a keyword to filter the displayed items

inorganic chemistry coordination chemistry transition metal chemistry pharmacology molecular biology chemistry biological inorganic chemistry medicinal chemistry biochemistry oncology tumor biology structural biology cancer research medicinal research organometallic chemistry anti-cancer agents tumor targeting inorganic synthesis cancer treatment drug discovery enzyme inhibition molecular cancer coordination complex cancer biology structural molecular biology nucleic acids structural chemistry protein science pharmacotherapy dna binding inorganic compounds dinuclear platinum complexes molecular structure molecular complexes material chemistry cancer genomics organometallic catalysis metal complexes brain tumor research antiviral research functional modification pharmaceutical chemistry drug targeting chemical sciences biological chemistry dna nanotechnology platinum complexes dna analysis conformational studies protein chemistry biomolecular interactions geometric isomerism rna biology clinical pharmacology metal toxicity dna sequencing surface reactivity clinical therapeutics biological activity trinuclear platinum complex antitumor activity phosphate clamp therapeutic efficacy catalyst activation virus-host interactions antiviral therapy synthetic chemistry radiation chemistry metalloproteins polynuclear platinum complexes platinum compounds conformational changes dna interactions dna-dna interstrand cross-links trinuclear platinum complexes anticancer agents medicine infection control clinical infectious disease infectious diseases infectious diseases (medical specialty)

Notable Scholarly Works

Notable Federal Grants

Collaborators

Mitochondrial Disease Patients and Rotavirus Infection Complications. Journal of Allergy & Infectious Diseases (2024)

Savannah BattlesonAnna BetlerHayden DiversJack KloeckerIradukunda EsperanceNicholas FarrellMolly SawyerAzhar RahamaOjus DalviGary Vanderlaan

mitochondrial disease patientsallergyrespiratory medicinehepatologyinfectious diseaseshealth sciences

Spermine and Spermidine Si-Ppcs: Molecular Dynamics Reveals Enhanced Biomolecular Interactions. International Journal of Biological Macromolecules (2024)

Frederico Henrique do C. FerreiraNicholas P. FarrellLuiz Antônio S. Costa

biomolecular interactionsbiological macromoleculesbiochemistryspermidine si-ppcs

A Comparison of DI- and Trinuclear Platinum Complexes Interacting With Glycosaminoglycans for Targeted Chemotherapy. ACS Medicinal Chemistry Letters (2023)

Samantha J. KatnerEric P. GinsburgJames D. HamptonErica J. PetersonJennifer E. KoblinskiNicholas P. Farrell

medicinal chemistrytumor targetingmedicinepharmaceutical chemistrypharmacologytargeted chemotherapyclinical chemistryclinical therapeuticscoordination chemistrypharmacotherapytrinuclear platinum complexesdrug discoveryoncologyinorganic chemistrydrug targetingcancer treatmenttransition metal chemistry

Antitumor Active Trans‑Platinum Complexes Through Metabolic Stability and Enhanced Cellular Accumulation. Journal of Inorganic Biochemistry (2023)

Vijay MenonSamantha J. KatnerDaniel E. LeeErica J. PetersonJennifer E. KoblinskiNicholas P. Farrell

pharmacologycoordination chemistrycellular accumulationmetabolic stabilityinorganic chemistrytransition metal chemistry

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

biophysicsstructure elucidationcrystal researchcrystal diffraction studystructure determinationstructural chemistryccdc 2157502chemistrydeposited datasetcrystal engineeringchemical structurecrystal structurescrystallography

Glycosaminoglycan-Directed Cobalt Complexes. Journal of Inorganic Biochemistry (2023)

Jessica M. ChristianMary ZoepflWyatt E. JohnsonEric GinsburgErica J. PetersonJ. David HamptonNicholas P. Farrell

glycosaminoglycan-directed cobalt complexescoordination chemistryinorganic chemistrybiochemistrytransition metal chemistry

Probing Disaccharide Binding to Triplatin as Models for Tumor Cell Heparan Sulfate (Gag) Interactions. Inorganic Chemistry (2023)

Anil K. GorleAlpeshkumar K. MaldeChih-Wei ChangPremraj RajaratnamMark von ItzsteinSusan J. Berners-PriceNicholas P. Farrell

biomolecular interactionspharmacologyprotein modelingmolecular modellingcoordination chemistrybiomolecular engineeringbiological inorganic chemistrymolecular biologystructural molecular biologyinorganic chemistrystructural biologyprotein sciencetumor biology

Supplementary Figures From Exploitation of Sulfated Glycosaminoglycan Status for Precision Medicine of Triplatin in Triple-Negative Breast Cancer. (2023)

James D. HamptonErica J. PetersonSamantha J. KatnerTia H. TurnerMohammad A. AlzubiJ. Chuck HarrellMikhail G. DozmorovJoseph B. McGee TurnerPam J. GigliottiVita KraskauskieneMayuri ShendeMichael O. IdowuMadhavi PuchalapalliBin HuLarisa LitovchickEriko KatsutaKazuaki TakabeNicholas P. FarrellJennifer E. Koblinski

nanomedicineshort-term variabilitysulfated glycosaminoglycan statusbreast oncologyneurologytriple-negative breast cancercancer careanti-cancer agentsbreast cancerhealth sciencescancer researchcancer immunotherapycancer treatmentsupplementary figuresmedical mycologyenzyme inhibitionpharmacologyoncologymedicinal research

Thiazole Orange-Carboplatin Triplex-Forming Oligonucleotide (Tfo) Combination Probes Enhance Targeted Dna Crosslinking. RSC Medicinal Chemistry (2023)

Joseph HennessyPiotr KlimkowskiDaniel SingletonAlex GibneyMalou CocheNicholas P. FarrellAfaf H. El-SagheerTom BrownAndrew Kellett

medicinal chemistrygene therapymedicinepharmacologycombination probesdna crosslinkingdrug discoverymolecular biologyoligonucleotidesnanotechnologydrug development

Controlling Nuclease Degradation of Wireframe Dna Origami With Minor Groove Binders. ACS Nano (2022)

Eike-Christian WamhoffAnna RomanovHellen HuangBenjamin J. ReadEric GinsburgGrant A. KnappeHyun Min KimNicholas P. FarrellDarrell J. IrvineMark Bathe

nanobiotechnologymaterials sciencedna nanotechnologynuclease degradationbiomolecular engineeringwireframe dna origamiminor groove bindersnanotechnologybiological engineeringnanometrologynanoengineering

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Nicholas Farrell

Emeritus

Virginia Commonwealth University

Affiliations

College of Humanities and Sciences

Department of Chemistry

Nicholas Farrell is currently serving as a College Of Humanities And Sciences Emeritus at Virginia Commonwealth University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Nicholas Farrell

Virginia Commonwealth University

Emeritus

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Mitochondrial Disease Patients and Rotavirus Infection Complications. Journal of Allergy & Infectious Diseases (2024)

Savannah BattlesonAnna BetlerHayden DiversJack KloeckerIradukunda EsperanceNicholas FarrellMolly SawyerAzhar RahamaOjus DalviGary Vanderlaan

mitochondrial disease patientsallergyrespiratory medicinehepatologyinfectious diseaseshealth sciences

Spermine and Spermidine Si-Ppcs: Molecular Dynamics Reveals Enhanced Biomolecular Interactions. International Journal of Biological Macromolecules (2024)

Frederico Henrique do C. FerreiraNicholas P. FarrellLuiz Antônio S. Costa

biomolecular interactionsbiological macromoleculesbiochemistryspermidine si-ppcs

A Comparison of DI- and Trinuclear Platinum Complexes Interacting With Glycosaminoglycans for Targeted Chemotherapy. ACS Medicinal Chemistry Letters (2023)

Samantha J. KatnerEric P. GinsburgJames D. HamptonErica J. PetersonJennifer E. KoblinskiNicholas P. Farrell

Antitumor Active Trans‑Platinum Complexes Through Metabolic Stability and Enhanced Cellular Accumulation. Journal of Inorganic Biochemistry (2023)

Vijay MenonSamantha J. KatnerDaniel E. LeeErica J. PetersonJennifer E. KoblinskiNicholas P. Farrell

pharmacologycoordination chemistrycellular accumulationmetabolic stabilityinorganic chemistrytransition metal chemistry

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

Glycosaminoglycan-Directed Cobalt Complexes. Journal of Inorganic Biochemistry (2023)

Jessica M. ChristianMary ZoepflWyatt E. JohnsonEric GinsburgErica J. PetersonJ. David HamptonNicholas P. Farrell

glycosaminoglycan-directed cobalt complexescoordination chemistryinorganic chemistrybiochemistrytransition metal chemistry

Probing Disaccharide Binding to Triplatin as Models for Tumor Cell Heparan Sulfate (Gag) Interactions. Inorganic Chemistry (2023)

Anil K. GorleAlpeshkumar K. MaldeChih-Wei ChangPremraj RajaratnamMark von ItzsteinSusan J. Berners-PriceNicholas P. Farrell

Supplementary Figures From Exploitation of Sulfated Glycosaminoglycan Status for Precision Medicine of Triplatin in Triple-Negative Breast Cancer. (2023)

Thiazole Orange-Carboplatin Triplex-Forming Oligonucleotide (Tfo) Combination Probes Enhance Targeted Dna Crosslinking. RSC Medicinal Chemistry (2023)

Joseph HennessyPiotr KlimkowskiDaniel SingletonAlex GibneyMalou CocheNicholas P. FarrellAfaf H. El-SagheerTom BrownAndrew Kellett

medicinal chemistrygene therapymedicinepharmacologycombination probesdna crosslinkingdrug discoverymolecular biologyoligonucleotidesnanotechnologydrug development

Controlling Nuclease Degradation of Wireframe Dna Origami With Minor Groove Binders. ACS Nano (2022)

Eike-Christian WamhoffAnna RomanovHellen HuangBenjamin J. ReadEric GinsburgGrant A. KnappeHyun Min KimNicholas P. FarrellDarrell J. IrvineMark Bathe

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