Faculty

Institution

Unit

Venue

Ines Batinic-Haberle

Professor Emeritus of Radiation Oncology

Duke University

Affiliations

School of Medicine

Clinical Science Departments

Department of Radiation Oncology

Ines Batinic-haberle is currently serving as a Clinical Science S Professor Emeritus of Radiation Oncology at Duke University.

Honors

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Experiences

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Education

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Ines Batinic-Haberle

Duke University

Professor Emeritus of Radiation Oncology

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oxidative stress free radical biology redox biology biochemistry pharmacology molecular biology reactive oxygen species medicine transition metal chemistry antioxidants redox signaling medicinal research medicinal chemistry enzyme inhibition oncology redox chemistry chemical biology coordination chemistry enzymes membrane biology radiation biology vascular biology inorganic chemistry protein science radiation therapy inflammation mn porphyrins inhibitory activity cancer biology structural chemistry brain tumor research mitochondrial function neuroprotection treatment effects manganese porphyrins photomedicine biological inorganic chemistry anti-cancer agents cancer treatment biological chemistry photobiology photodynamic therapy therapeutic efficacy superoxide dismutase dalton transaction surface reactivity reductive stress redox regulator coordination complex sod mimics cell metabolism chemical sciences radical (chemistry) selective separation catalyst activation inorganic synthesis functional modification novel therapies manganese porphyrin radiation chemistry hypoxia (medicine) neurochemistry pharmaceutical chemistry lipid peroxidation enzyme catalysis second-sphere coordination therapeutic effects mn porphyrin superoxide dismutase mimics radiation-induced injury redox-active therapeutics redox-active compounds therapeutic potential manganese superoxide dismutase superoxide dismutation structure-activity relationships

Notable Scholarly Works

Notable Federal Grants

Collaborators

Brain Distribution of Rotational Isomers of a Superoxide Dismutase Mimic Bmx-001. Free Radical Biology and Medicine (2024)

Gerold KaplanAndrea ChiappettiTigran MargaryanLinnu ShajiWilliam KnightIvan SpasojevicInes Batinic-HaberleShwetal MehtaNader SanaiArtak Tovmasyan

biophysicsrotational isomersneuroimagingfree radical biologyredox biologyneurochemistryreactive oxygen speciesbrain distributionbiomolecular engineeringcentral nervous systemoxidative stressneuroscience

Impact of the Redox-Active Mntnhex-2-Pyp5+ and Cisplatin on the Metabolome of Non-Small Cell Lung Cancer Cells. Biochemical Pharmacology (2024)

Rita B. SoaresJoana PintoFilipa AmaroRita ManguinhasNuno GilRafael RosellInes Batinic-HaberleAna S. FernandesNuno G. OliveiraPaula Guedes de Pinho

lung cancerredox biologybiochemistrymetabolomics

Mapping Manganese Porphyrin Drug Action. Free Radical Biology and Medicine (2024)

Ines Batinic-HaberleIvan SpasojevicArtak TovmasyanSilky SilkyGregory Giles

medicinepharmacologyfree radical biologytherapeutic targetsdrug discoverymedicinal researchoxidative stressdrug targets

Redox-Active Mn Porphyrin-Based Clinical Candidate, Mntnbuoe-2-Pyp5+ (Bmx-001) Reduces Paclitaxel-Induced Neuropathy, While Suppressing Ovarian Cancer Growth. Free Radical Biology and Medicine (2024)

Ivan SpasojevicWelida Tamires Alves da SilvaZhiqing HuangWeina DuanLi DuCathleen ChenJie CaoShasha ZhangHannah LeeGaomong LoJihua FengBella MendietaArtak TovmasyanHuaxin ShengInes Batinic-HaberleAngeles Alvarez Secord

medicinepaclitaxel-induced neuropathyovarian cancer growthfree radical biologycancer growthovarian cancer

Single-Cell Profiling Reveals Immune-Based Mechanisms Underlying Tumor Radiosensitization by a Novel Mn Porphyrin Clinical Candidate, Mntnbuoe-2-Pyp5+ (Bmx-001). Antioxidants (2024)

Sun Up NohJinyeong LimSung-Won ShinYeeun KimWoong-Yang ParkInes Batinic-HaberleChanghoon ChoiWon Park

immunologyantioxidantstumor radiosensitizationtumor microenvironment

Effect of the Nature of the Chelated Metal on the Photodynamic Activity of Metalloporphyrins. Free Radical Research (2023)

Ghadeer AbbasFatemah AlibrahimRawan KankouniSara Al-BelushiDalal A. Al-MutairiArtak TovmasyanInes Batinic-HaberleLudmil Benov

chelated metalfree radical biologyphotochemistrychemistryphotodynamic activitytransition metal chemistry

Formation and Decomposition of the Mn(II)P-No Complex in Vitro: Potential Role in Mitochondrial Peroxynitrite Formation. Free Radical Biology and Medicine (2023)

Valeria ValezAdrian AicardoSebastian CarballalVeronica DemicheliInes Batinic-HaberleDaniel MurgidaRafael Radi

free radical biologyredox biologymitochondrial functionmolecular biologyoxidative stressmitochondrial peroxynitrite formationbiochemistry

Intracarotid Infusion of Redox-Active Manganese Porphyrin, Mntnbuoe-2-Pyp5+, Following Reperfusion Improves Long-Term, 28-Day Post-Stroke Outcomes in Rats. Antioxidants (2023)

Xuan LiWeina DuanLi DuDongmei ChuPeng WangZhong YangXingguang QuZhenxing YangInes Batinic-HaberleIvan SpasojevicDavid S. WarnerJames D. CrapoMiriam M. TreggiariHuaxin Sheng

physiologyneurologyredox-active manganese porphyrinpharmacologyregenerative medicinefree radical biologyreperfusion injurysurvival analysisredox biologyantioxidantsintracarotid infusionstroke rehabilitationstrokeoxidative stressmembrane biology

Ltbk-09. Results of Bmx-Hgg Study: A Multi-Institutional, Randomized Phase 2 Clinical Trial of Concurrent Chemoradiation With or Without Bmx-001 in Patients With Newly Diagnosed High Grade Glioma. Neuro-Oncology (2023)

Katherine PetersAdam CohenNicholas ButowskiJohn VillanoJoe MendezPierre GiglioTresa McGranahanChi ZhangJacob SmeltzerShahzad RazaBurt NaborsMina LobbousJames HerndonEvan BuckleyDavid MacLeodSara PenchevDavid SilbersteinInes Batinic-HaberleIvan SpasojevicShayne GadDavid RadoffDaniel BarboriakJames Crapo

medicinegliomasradiation oncologybrain tumor researchbmx-hgg studyhigh grade gliomaclinical trialsoncologyneuro-oncologyradiation therapyradiationconcurrent chemoradiationneuroscience

Mn(III) Porphyrin, Mntnbuoe-2-Pyp5+, Commonly Known as a Mimic of Superoxide Dismutase Enzyme, Protects Cardiomyocytes From Hypoxia/Reoxygenation Induced Injury via Reducing Oxidative Stress. International Journal of Molecular Sciences (2023)

Sudha SharmaPapori SharmaUtsab SubediSusmita BhattaraiChloe MillerShrivats ManikandanInes Batinic-HaberleIvan SpasojevicHong SunManikandan PanchatcharamSumitra Miriyala

superoxide dismutase enzymeredox signalingfree radical biologycardiovascular researchredox biologymolecular and cellular biologyantioxidantsreactive oxygen speciesenzyme specificitybiomolecular engineeringenzymesbioactive compoundsmolecular biologystructural molecular biologyoxidative stressbiochemistry

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Ines Batinic-Haberle

Professor Emeritus of Radiation Oncology

Duke University

Affiliations

School of Medicine

Clinical Science Departments

Department of Radiation Oncology

Ines Batinic-haberle is currently serving as a Clinical Science S Professor Emeritus of Radiation Oncology at Duke University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ines Batinic-Haberle

Duke University

Professor Emeritus of Radiation Oncology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Brain Distribution of Rotational Isomers of a Superoxide Dismutase Mimic Bmx-001. Free Radical Biology and Medicine (2024)

Gerold KaplanAndrea ChiappettiTigran MargaryanLinnu ShajiWilliam KnightIvan SpasojevicInes Batinic-HaberleShwetal MehtaNader SanaiArtak Tovmasyan

Impact of the Redox-Active Mntnhex-2-Pyp5+ and Cisplatin on the Metabolome of Non-Small Cell Lung Cancer Cells. Biochemical Pharmacology (2024)

Rita B. SoaresJoana PintoFilipa AmaroRita ManguinhasNuno GilRafael RosellInes Batinic-HaberleAna S. FernandesNuno G. OliveiraPaula Guedes de Pinho

lung cancerredox biologybiochemistrymetabolomics

Mapping Manganese Porphyrin Drug Action. Free Radical Biology and Medicine (2024)

Ines Batinic-HaberleIvan SpasojevicArtak TovmasyanSilky SilkyGregory Giles

medicinepharmacologyfree radical biologytherapeutic targetsdrug discoverymedicinal researchoxidative stressdrug targets

medicinepaclitaxel-induced neuropathyovarian cancer growthfree radical biologycancer growthovarian cancer

Single-Cell Profiling Reveals Immune-Based Mechanisms Underlying Tumor Radiosensitization by a Novel Mn Porphyrin Clinical Candidate, Mntnbuoe-2-Pyp5+ (Bmx-001). Antioxidants (2024)

Sun Up NohJinyeong LimSung-Won ShinYeeun KimWoong-Yang ParkInes Batinic-HaberleChanghoon ChoiWon Park

immunologyantioxidantstumor radiosensitizationtumor microenvironment

Effect of the Nature of the Chelated Metal on the Photodynamic Activity of Metalloporphyrins. Free Radical Research (2023)

Ghadeer AbbasFatemah AlibrahimRawan KankouniSara Al-BelushiDalal A. Al-MutairiArtak TovmasyanInes Batinic-HaberleLudmil Benov

chelated metalfree radical biologyphotochemistrychemistryphotodynamic activitytransition metal chemistry

Formation and Decomposition of the Mn(II)P-No Complex in Vitro: Potential Role in Mitochondrial Peroxynitrite Formation. Free Radical Biology and Medicine (2023)

Valeria ValezAdrian AicardoSebastian CarballalVeronica DemicheliInes Batinic-HaberleDaniel MurgidaRafael Radi

free radical biologyredox biologymitochondrial functionmolecular biologyoxidative stressmitochondrial peroxynitrite formationbiochemistry

Intracarotid Infusion of Redox-Active Manganese Porphyrin, Mntnbuoe-2-Pyp5+, Following Reperfusion Improves Long-Term, 28-Day Post-Stroke Outcomes in Rats. Antioxidants (2023)

Xuan LiWeina DuanLi DuDongmei ChuPeng WangZhong YangXingguang QuZhenxing YangInes Batinic-HaberleIvan SpasojevicDavid S. WarnerJames D. CrapoMiriam M. TreggiariHuaxin Sheng

medicinegliomasradiation oncologybrain tumor researchbmx-hgg studyhigh grade gliomaclinical trialsoncologyneuro-oncologyradiation therapyradiationconcurrent chemoradiationneuroscience

Sudha SharmaPapori SharmaUtsab SubediSusmita BhattaraiChloe MillerShrivats ManikandanInes Batinic-HaberleIvan SpasojevicHong SunManikandan PanchatcharamSumitra Miriyala

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