Faculty

Institution

Unit

Venue

Michael E Johnson

Professor Emeritus

University of Illinois Chicago

Affiliations

Herbert M. and Carol H. Retzky College of Pharmacy

Pharmaceutical Sciences

Michael E Johnson is currently serving as a Herbert M. And Carol H. Retzky College Of Pharmacy Professor Emeritus at University of Illinois Chicago.

Honors

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Experiences

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Education

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Michael E Johnson

University of Illinois Chicago

Professor Emeritus

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pharmacology medicinal chemistry drug discovery biochemistry structural biology molecular biology protein science medicine enzymes enzyme inhibition protein structure bioorganic chemistry antiviral drug development pharmaceutical chemistry chemical synthesis virology antiviral research clinical chemistry structural molecular biology medicinal research peptide synthesis virus research clinical microbiology biomolecular structure pharmaceutical sciences rational drug design structure determination biological chemistry applied microbiology biochemical sciences peptides protein chemistry drug targeting general virology antimicrobial agents electron paramagnetic resonance drug development antiviral therapy molecular recognition protein nmr crystal structures x-ray crystallography biological evaluation bacillus anthracis structure-based design conformational analysis pharmacotherapy clinical pharmacology pharmaceutical biotechnology viral structural protein antiviral compounds antiviral drugs phytochemistry high-throughput screening viral hepatitis protein expression protein purification experimental biophysics heterocyclic heterocycle chemistry heme trafficking antimicrobial chemotherapy saturation transfer novel series small molecule inhibitors virus-host interactions molecular virology mers-cov papain-like protease mycobacterium tuberculosis spin label inhibitor design implications benzimidazole-based fabi inhibitors nmr data benzimidazole inhibitors rapid motions staphylococcus aureus dihydroorotase computational biology structural bioinformatics staphylococcus aureus signal transduction molecular technology biomolecular engineering

Notable Scholarly Works

Notable Federal Grants

Collaborators

Discovery and Characterization of Highly Potent and Selective Covalent Inhibitors of Sars-Cov-2 Plpro. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Jian WuTasneem M. VaidHoshin KimJun LuRobel DemissieHyun LeeLeslie W.-M. FungJia ChenChenghao XiZhezhou YangYu HuangZhantao ZhangJingqing ZhangFengfeng YanMichael E. JohnsonMin Li

antiviral drug developmentselective covalent inhibitorsmedicinal chemistrysars-cov-2biochemistrypharmacologymolecular biologydrug discoveryvirus research

Mapping the Energy Landscape of Protac-Mediated Protein-Protein Interactions. Computational and Structural Biotechnology Journal (2023)

José A. VillegasTasneem M. VaidMichael E. JohnsonTerry W. Moore

biophysicsbiological engineeringenergy landscapeprotac-mediated protein-protein interactionssystems biologycomputational biologybiotechnologycomputational biophysicsstructural biology

Synergistic Inhibition Guided Fragment-Linking Strategy and Quantitative Structure–Property Relationship Modeling to Design Inhalable Therapeutics for Asthma Targeting Csf1r. ACS Omega (2023)

Tasneem M. VaidRobel DemissieYoungjin KwonThao TranHyung-Geun MoonJosé A. VillegasGye Young ParkMichael E. JohnsonHyun Lee

synergistic inhibitiondermatologyquantitative structure-property relationshipimmunotherapyimmunologypharmacologyrespiratory medicinefragment-linking strategyrational drug designdrug discoveryasthmamedicinal researchinhalable therapeutics

Evaluation of Interactions Between the Hepatitis C Virus Ns3/4A and Sulfonamidobenzamide Based Molecules Using Molecular Docking, Molecular Dynamics Simulations and Binding Free Energy Calculations. Journal of Computer-Aided Molecular Design (2022)

Jinhong RenTasneem M. VaidHyun LeeIsabel OjedaMichael E. Johnson

molecular dynamics simulationspharmacologymolecular dockingnanotechnology

Identification of Small Molecule Inhibitors Against Staphylococcus Aureus Dihydroorotase via Hts. International Journal of Molecular Sciences (2021)

Amy J. RiceRussell P. PesaventoJinhong RenIsoo YounYoungjin KwonKassapa EllepolaChun-Tao CheMichael E. JohnsonHyun Lee

small molecule inhibitorsenzymeslead identificationstaphylococcus aureus dihydroorotasemedicinal chemistryimmunologypharmacologybiochemistrydrug targetingmolecular pharmacologyenzyme inhibitiondrug discovery

Baicalein is a Phytohormone That Signals Through the Progesterone and Glucocorticoid Receptors. Hormones and Cancer (2020)

Julia R. AustinBrenna J. KirkpatrickRocío Rivera RodríguezMichael E. JohnsonDaniel D. LantvitJoanna E. Burdette

endocrinologyglucocorticoid receptorspharmacology

Cytotoxic and Non-Cytotoxic Cardiac Glycosides Isolated From the Combined Flowers, Leaves, and Twigs of Streblus Asper. Bioorganic & Medicinal Chemistry (2020)

Yulin RenQingwei TanKimberly HeathSijin WuJames R. WilsonJinhong RenPratik ShriwasChunhua YuanTran Ngoc NinhHee-Byung ChaiXiaozhuo ChenDjaja D. SoejartoMichael E. JohnsonXiaolin ChengJoanna E. BurdetteA. Douglas Kinghorn

plant biologycombined flowersorganic chemistryphytochemistrymedicinal chemistrypharmacologystreblus asper

Na+/K+ Atpase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives. Journal of Natural Products (2020)

pharmaceutical chemistrypharmacological researchoxidative stressbioactive compoundsmedicinal chemistrybiochemistrypharmacologycellular pharmacologymolecular pharmacologyna+/k+ atpase-targeted cytotoxicityenzyme inhibitiondrug discoveryredox signaling

Na + /K + -Atpase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives. Journal of Natural Products (2020)

Yulin RenHennrique T. RibasKimberly HeathSijin WuJinhong RenPratik ShriwasXiaozhuo ChenMichael E. JohnsonXiaolin ChengJoanna E. BurdetteA. Douglas Kinghorn

biochemistrypharmacologynatural product researchenzyme inhibitiondrug discoverytoxicology

Structural Approaches to Pathway-Specific Antimicrobial Agents. Translational research (2020)

Michael E. JohnsonLeslie W.-M. Fung

pathway analysistranslational medicinepathway-specific antimicrobial agentspharmacologytranslational researchdrug discoveryapplied microbiologystructural biologystructural chemistry

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Michael E Johnson

Professor Emeritus

University of Illinois Chicago

Affiliations

Herbert M. and Carol H. Retzky College of Pharmacy

Pharmaceutical Sciences

Michael E Johnson is currently serving as a Herbert M. And Carol H. Retzky College Of Pharmacy Professor Emeritus at University of Illinois Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Michael E Johnson

University of Illinois Chicago

Professor Emeritus

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Discovery and Characterization of Highly Potent and Selective Covalent Inhibitors of Sars-Cov-2 Plpro. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Jian WuTasneem M. VaidHoshin KimJun LuRobel DemissieHyun LeeLeslie W.-M. FungJia ChenChenghao XiZhezhou YangYu HuangZhantao ZhangJingqing ZhangFengfeng YanMichael E. JohnsonMin Li

antiviral drug developmentselective covalent inhibitorsmedicinal chemistrysars-cov-2biochemistrypharmacologymolecular biologydrug discoveryvirus research

Mapping the Energy Landscape of Protac-Mediated Protein-Protein Interactions. Computational and Structural Biotechnology Journal (2023)

José A. VillegasTasneem M. VaidMichael E. JohnsonTerry W. Moore

biophysicsbiological engineeringenergy landscapeprotac-mediated protein-protein interactionssystems biologycomputational biologybiotechnologycomputational biophysicsstructural biology

Synergistic Inhibition Guided Fragment-Linking Strategy and Quantitative Structure–Property Relationship Modeling to Design Inhalable Therapeutics for Asthma Targeting Csf1r. ACS Omega (2023)

Tasneem M. VaidRobel DemissieYoungjin KwonThao TranHyung-Geun MoonJosé A. VillegasGye Young ParkMichael E. JohnsonHyun Lee

Jinhong RenTasneem M. VaidHyun LeeIsabel OjedaMichael E. Johnson

molecular dynamics simulationspharmacologymolecular dockingnanotechnology

Identification of Small Molecule Inhibitors Against Staphylococcus Aureus Dihydroorotase via Hts. International Journal of Molecular Sciences (2021)

Amy J. RiceRussell P. PesaventoJinhong RenIsoo YounYoungjin KwonKassapa EllepolaChun-Tao CheMichael E. JohnsonHyun Lee

Baicalein is a Phytohormone That Signals Through the Progesterone and Glucocorticoid Receptors. Hormones and Cancer (2020)

Julia R. AustinBrenna J. KirkpatrickRocío Rivera RodríguezMichael E. JohnsonDaniel D. LantvitJoanna E. Burdette

endocrinologyglucocorticoid receptorspharmacology

Cytotoxic and Non-Cytotoxic Cardiac Glycosides Isolated From the Combined Flowers, Leaves, and Twigs of Streblus Asper. Bioorganic & Medicinal Chemistry (2020)

plant biologycombined flowersorganic chemistryphytochemistrymedicinal chemistrypharmacologystreblus asper

Na+/K+ Atpase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives. Journal of Natural Products (2020)

Na + /K + -Atpase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives. Journal of Natural Products (2020)

Yulin RenHennrique T. RibasKimberly HeathSijin WuJinhong RenPratik ShriwasXiaozhuo ChenMichael E. JohnsonXiaolin ChengJoanna E. BurdetteA. Douglas Kinghorn

biochemistrypharmacologynatural product researchenzyme inhibitiondrug discoverytoxicology

Structural Approaches to Pathway-Specific Antimicrobial Agents. Translational research (2020)

Michael E. JohnsonLeslie W.-M. Fung

pathway analysistranslational medicinepathway-specific antimicrobial agentspharmacologytranslational researchdrug discoveryapplied microbiologystructural biologystructural chemistry

1
2
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4
5
17
10 / page

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Similar Faculty Members

Charles E. McKenna

Institution

University of Southern California

future medicinal chemistry

medicinal chemistry

Peter J. Tonge

Institution

Stony Brook University

biological data

biomedical informatics

Dale F. Mierke

Institution

Dartmouth College

high resolution nmr

biomolecular engineering

Scott G. Franzblau

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antibiotic

tuberculosis

Chang-Guo Zhan

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future medicinal chemistry

molecular docking

Stephen Hanessian

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University of California, Irvine

organic chemistry

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Richard B. Silverman

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pharmacology

medicinal chemistry

Lai-Xi Wang

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University of Maryland, College Park

immunology

biochemistry

Courtney Aldrich

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University of Minnesota

medicinal chemistry

pharmacology

Jianfeng Cai

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protein-protein interactions

biomolecular engineering