Faculty

Institution

Unit

Venue

Michael C. Fitzgerald

Professor

Duke University

Affiliations

Duke University School of Medicine

Biochemistry

Trinity College of Arts & Sciences

Chemistry

Michael C. Fitzgerald is currently serving as a Biochemistry Professor at Duke University.

Honors

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Experiences

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Education

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Michael C. Fitzgerald

Duke University

Professor

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biophysics mass spectrometry protein science molecular biology proteomics structural biology biochemistry analytical chemistry protein folding pharmacology thermodynamic analysis enzymes thermodynamics protein structure protein chemistry enzyme inhibition biological inorganic chemistry structural molecular biology cancer biology protein-ligand binding interactions clinical proteomics biological chemistry redox biology transition metal chemistry conformational studies hydrogen bond ligand binding protein stability complex biological mixtures mass spectrometry-based method stability measurements maldi-tof data medicinal research molecular diagnostics clinical biochemistry clinical microbiology biochemical sciences high-throughput screening cancer genomics biomedical research enzyme catalysis protein function protein transport protein mass spectrometry microbial physiology protein-drug interactions proteomic scale total chemical synthesis large-scale analysis large-scale protein folding thermodynamic stability protein-ligand binding analysis protein target discovery thoracic oncology respiratory medicine molecular cell biology clinical chemistry tumor targeting clinical medicine spectral analysis cancer detection radiation chemistry analytical biotechnology dna sequencing dna analysis sequence analysis genome analysis enzymatic modification experimental biophysics biomolecular interactions protein bioinformatics treatment effects in vivo systems sample preparation antiviral therapy combinatorial chemistry biomolecular engineering protein refolding biomolecular structure molecular biophysics disease detection protein modeling

Notable Scholarly Works

Notable Federal Grants

Collaborators

Analysis of Brain Protein Stability Changes in a Mouse Model of Alzheimer’s Disease. Journal of Proteome Research (2024)

Yun TangHye-Jin ParkShengyu LiMichael C. Fitzgerald

proteome researchalzheimer's diseaseneurodegenerative diseasesprotein scienceneuroscienceproteomicsmouse model

Selective Targeting of Plasmodium Falciparum Hsp90 Disrupts the 26S Proteasome. Cell chemical biology (2024)

Christopher R. MansfieldBaiyi QuanMichael E. ChirgwinBenjamin EdufulPhilip F. HughesGaëlle NeveuKayla SylvesterDaniel H. RyanBjörn F.C. KafsackTimothy A.J. HaysteadJames W. LeahyMichael C. FitzgeraldEmily R. Derbyshire

infectious diseasescell biologymalariamolecular biologyselective targeting

Stability-Based Proteomics for Investigation of Structured Rna–Protein Interactions. Analytical Chemistry (2024)

Morgan A. BaileyJustin G. MartyrAmanda E. HargroveMichael C. Fitzgerald

proteomicsmolecular biologystability-based proteomicsstructured rna-protein interactionsanalytical chemistrystructural biology

Top-Down Stability of Proteins From Rates of Oxidation (Td-Sprox) Approach for Measuring Proteoform-Specific Folding Stability. Analytical Chemistry (2024)

You ZouChe-Fan HuangGrace R. SturrockNeil L. KelleherMichael C. Fitzgerald

biophysicsproteoform-specific folding stabilityprotein sciencebiomolecular structureprotein structureprotein foldingbiochemistrystructural molecular biologyprotein modelingmolecular biologytop-down stabilityanalytical chemistrybiophysical chemistrystructural biology

Comparative Analysis of Protein Folding Stability-Based Profiling Methods for Characterization of Biological Phenotypes. Journal of the American Society for Mass Spectrometry (2023)

Morgan A. BaileyYun TangHye-Jin ParkMichael C. Fitzgerald

biophysicsbiological phenotypesmass spectrometrystability-based profiling methodsprotein foldingproteomics

Protein Folding Stability Profiling of Colorectal Cancer Chemoresistance Identifies Functionally Relevant Biomarkers. Journal of Proteome Research (2023)

Baiyi QuanMorgan A. BaileyJohn MantyhDavid S. HsuMichael C. Fitzgerald

biophysicstumor biologycolorectal canceroncologycancer biologyprotein scienceprotein foldingpharmacologyproteomicsclinical proteomicshealth sciencesstructural biology

Analysis of Copper-Induced Protein Precipitation Across the E. Coli Proteome. Metallomics (2022)

Amy T R RobisonGrace R SturrockJacqueline M Zaengle-BaroneNancy WiebelhausAzim DharaniIsabella G WilliamsMichael C FitzgeraldKatherine J Franz

elemental metalinorganic chemistryinfectious diseasesprotein sciencemetalsbiological inorganic chemistrymaterials scienceproteomicscopper-induced protein precipitationtransition metal chemistrymicrobial proteomicsstructural biology

Bet V 1 and Other Birch Allergens Are More Resistant to Proteolysis and More Abundant Than Other Birch Pollen Proteins. Allergy (2022)

Aurora CabreraAlexander C. Y. FooMichael C. FitzgeraldGeoffrey A. Mueller

allergy

Discovery of the Xenon–Protein Interactome Using Large-Scale Measurements of Protein Folding and Stability. Journal of the American Chemical Society (2022)

Nancy WiebelhausNiven SinghPeng ZhangStephen L. CraigDavid N. BeratanMichael C. Fitzgerald

biophysicsprotein foldingxenon-protein interactomeproteomicslarge-scale measurementsstructural biology

Analysis of Brain Protein Stability Changes in Mouse Models of Normal Aging and α-Synucleinopathy Reveals Age- and Disease-Related Differences. Journal of Proteome Research (2021)

Renze MaJulia H. R. JohnsonYun TangMichael C. Fitzgerald

neuroscience of agingneurodegenerative diseasesaging-associated diseasesgeriatricsmouse modelsneuroscienceageinggeriatric medicineproteomicsmammalian biologydisease-related differencesneurologydegenerative diseasehealth sciencesbiogerontologyexperimental gerontology

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Michael C. Fitzgerald

Professor

Duke University

Affiliations

Duke University School of Medicine

Biochemistry

Trinity College of Arts & Sciences

Chemistry

Michael C. Fitzgerald is currently serving as a Biochemistry Professor at Duke University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Michael C. Fitzgerald

Duke University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Analysis of Brain Protein Stability Changes in a Mouse Model of Alzheimer’s Disease. Journal of Proteome Research (2024)

Yun TangHye-Jin ParkShengyu LiMichael C. Fitzgerald

proteome researchalzheimer's diseaseneurodegenerative diseasesprotein scienceneuroscienceproteomicsmouse model

Selective Targeting of Plasmodium Falciparum Hsp90 Disrupts the 26S Proteasome. Cell chemical biology (2024)

infectious diseasescell biologymalariamolecular biologyselective targeting

Stability-Based Proteomics for Investigation of Structured Rna–Protein Interactions. Analytical Chemistry (2024)

Morgan A. BaileyJustin G. MartyrAmanda E. HargroveMichael C. Fitzgerald

proteomicsmolecular biologystability-based proteomicsstructured rna-protein interactionsanalytical chemistrystructural biology

Top-Down Stability of Proteins From Rates of Oxidation (Td-Sprox) Approach for Measuring Proteoform-Specific Folding Stability. Analytical Chemistry (2024)

You ZouChe-Fan HuangGrace R. SturrockNeil L. KelleherMichael C. Fitzgerald

Comparative Analysis of Protein Folding Stability-Based Profiling Methods for Characterization of Biological Phenotypes. Journal of the American Society for Mass Spectrometry (2023)

Morgan A. BaileyYun TangHye-Jin ParkMichael C. Fitzgerald

biophysicsbiological phenotypesmass spectrometrystability-based profiling methodsprotein foldingproteomics

Protein Folding Stability Profiling of Colorectal Cancer Chemoresistance Identifies Functionally Relevant Biomarkers. Journal of Proteome Research (2023)

Baiyi QuanMorgan A. BaileyJohn MantyhDavid S. HsuMichael C. Fitzgerald

biophysicstumor biologycolorectal canceroncologycancer biologyprotein scienceprotein foldingpharmacologyproteomicsclinical proteomicshealth sciencesstructural biology

Analysis of Copper-Induced Protein Precipitation Across the E. Coli Proteome. Metallomics (2022)

Amy T R RobisonGrace R SturrockJacqueline M Zaengle-BaroneNancy WiebelhausAzim DharaniIsabella G WilliamsMichael C FitzgeraldKatherine J Franz

Bet V 1 and Other Birch Allergens Are More Resistant to Proteolysis and More Abundant Than Other Birch Pollen Proteins. Allergy (2022)

Aurora CabreraAlexander C. Y. FooMichael C. FitzgeraldGeoffrey A. Mueller

allergy

Discovery of the Xenon–Protein Interactome Using Large-Scale Measurements of Protein Folding and Stability. Journal of the American Chemical Society (2022)

Nancy WiebelhausNiven SinghPeng ZhangStephen L. CraigDavid N. BeratanMichael C. Fitzgerald

biophysicsprotein foldingxenon-protein interactomeproteomicslarge-scale measurementsstructural biology

Analysis of Brain Protein Stability Changes in Mouse Models of Normal Aging and α-Synucleinopathy Reveals Age- and Disease-Related Differences. Journal of Proteome Research (2021)

Renze MaJulia H. R. JohnsonYun TangMichael C. Fitzgerald

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