Faculty

Institution

Unit

Venue

Megan Harwig

Medical College of Wisconsin

Affiliations

Physiology

NoneMegan Harwig is currently serving as a Physiology faculty at Medical College of Wisconsin.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Megan Harwig

Medical College of Wisconsin

You can click a keyword to filter the displayed items

molecular biology biochemistry biophysics vascular biology structural biology protein science mitochondrial dynamics vascular disease mitochondrial fission evolutionary biology therapeutic targets biophysical chemistry biological imaging biological chemistry medicinal research biomolecular structure mitochondrial function endothelial dysfunction biophysical modeling structural studies endocrinology oxidative stress genetic variation cancer immunotherapy redox biology mammalian biology oncogenes cancer cells structural molecular biology membrane science biological macromolecules peptide science peptides medical image computing biomedical imaging mitochondrial biogenesis tumor targeting melanoma therapeutic efficacy anti-cancer agents cancer immunosurveillance mutagenesis membrane systems intracellular trafficking membrane transport nuclear magnetic resonance spectroscopy protein nmr biomolecular interactions renal pathophysiology renal function kidney research bioimage analysis phase separation cardiovascular function yeast gene regulation mitophagy molecular regulation organellar form mammalian mitochondrial morphology divergent mechanisms melanoma progression synchronous effects immune cells human fission protein dynamic region yeast mitochondrial fission pk measurements postrecruitment role targeted mutation nucleosome phase separation membrane-bound state

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 4146321: Mitochondrial Fission Protein 1 (Fis1) Regulates Endothelial Function in Resistance Arterioles in Health and Cardiometabolic Disease. Circulation (2024)

Jingli WangKelsey NoldenJohn EgnerMamatha KakarlaMegan HarwigMichelle RobertsLeggy ArnoldBenjamin HofeldRong YingTaylor WilcoxR. HillMichael Widlansky

cardiovascular functioncardiometabolic diseaseresistance arteriolesvascular biologyendothelial functioncell biologycardiovascular disease

A Novel Automated Method for Comprehensive Renal Cast Quantification From Rat Kidney Sections Using Qupath. AJP Renal Physiology (2024)

Lauren YunkerMegan Cleland HarwigAlison J. Kriegel

physiologykidney researchrat kidney sectionsrenal functionnephrologyrenal pathophysiology

Human Fis1 Directly Interacts With Drp1 in an Evolutionarily Conserved Manner to Promote Mitochondrial Fission. Journal of Biological Chemistry (2023)

Kelsey A. NoldenMegan C. HarwigR. Blake Hill

mitochondrial fissionmolecular biologybiological chemistryevolutionary biologybiochemistry

The Variable Domain From Dynamin‐Related Protein 1 Promotes Liquid–Liquid Phase Separation That Enhances Its Interaction With Cardiolipin‐Containing Membranes. Protein Science (2023)

Ammon E. PoseyKyle A. RossMehran BagheriElizabeth N. LanumMisha A. KhanChristine E. JenningsMegan C. HarwigNolan W. KennedyVincent J. HilserJames L. HardenR. Blake Hill

biomolecular interactionsliquid-liquid phase separationbiophysicsbiomedical engineeringprotein structurevariable domainbiomolecular engineeringstructural biologycardiolipin-containing membranesprotein scienceprotein engineering

The Variable Domain From the Mitochondrial Fission Mechanoenzyme Drp1 Promotes Liquid-Liquid Phase Separation. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Ammon E. PoseyMehran BagheriKyle A. RossElizabeth N. LanumMisha A. KhanChristine M. JenningsMegan C. HarwigNolan W. KennedyVincent J. HilserJames L. HardenR. Blake Hill

liquid-liquid phase separationbiophysicsprotein structurevariable domainmolecular biologymembrane biologystructural biologyphase separationbiological engineering

Histone H3 and H4 Tails Play an Important Role in Nucleosome Phase Separation. Biophysical Chemistry (2022)

Erin F. HammondsMegan Cleland HarwigEmeleeta A. PaintsilEmma A. TillisonR. Blake HillEmma A. Morrison

nucleosome phase separationbiophysical chemistrybiophysics

Novel Dnm1L Variants Impair Mitochondrial Dynamics Through Divergent Mechanisms. Life Science Alliance (2022)

Kelsey A NoldenJohn M EgnerJack J CollierOliver M RussellCharlotte L AlstonMegan C HarwigMichael E WidlanskySouphatta SasorithInês A BarbosaAndrew GL DouglasJulia BaptistaMark WalkerDeirdre E DonnellyAndrew A MorrisHui Jeen TanManju A KurianKathleen GormanSantosh MordekarCharu DeshpandeRajib SamantaRobert McFarlandR Blake HillRobert W TaylorMonika Oláhová

mitochondrial dynamicsgeneticsbiologygenetic variationmolecular biologydivergent mechanisms

Structural Studies of Human Fission Protein Fis1 Reveal a Dynamic Region Important for Gtpase Drp1 Recruitment and Mitochondrial Fission. Journal of Biological Chemistry (2022)

John M. EgnerKelsey A. NoldenMegan Cleland HarwigRyan P. BonateJaime De AndaMaxx H. TessmerElizabeth L. NoeyUgochukwu K. IhenachoZiwen LiuFrancis C. PetersonGerard C.L. WongMichael E. WidlanskyR. Blake Hill

biophysicsstructural studieshuman fission proteinmolecular biologystructural biologydynamic regionbiochemistry

Intramolecular Regulation of Fis1 Activity in Fission and Mitophagy. The FASEB Journal (2021)

Ugochukwu IhenachoJohn EgnerMegan HarwigBlake Hill

gene regulationsystems biologycell signalingmolecular and cellular biologymolecular regulationintramolecular regulationmolecular cell biologymolecular biologymitophagysignal transductionautophagybiochemistry

Mitochondrial Fission Protein 1: Emerging Roles in Organellar Form and Function in Health and Disease. Frontiers in Endocrinology (2021)

Ugochukwu Kelvin IhenachoKelsey A. MeachamMegan Cleland HarwigMichael E. WidlanskyR. Blake Hill

mitochondrial dynamicsmitochondrial fissionorganellar formendocrinologyredox biologymitochondrial functionmolecular biologymitochondrial biogenesisoxidative stress

1
2
3
10 / page

Megan Harwig

Medical College of Wisconsin

Affiliations

Physiology

NoneMegan Harwig is currently serving as a Physiology faculty at Medical College of Wisconsin.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Megan Harwig

Medical College of Wisconsin

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 4146321: Mitochondrial Fission Protein 1 (Fis1) Regulates Endothelial Function in Resistance Arterioles in Health and Cardiometabolic Disease. Circulation (2024)

Jingli WangKelsey NoldenJohn EgnerMamatha KakarlaMegan HarwigMichelle RobertsLeggy ArnoldBenjamin HofeldRong YingTaylor WilcoxR. HillMichael Widlansky

cardiovascular functioncardiometabolic diseaseresistance arteriolesvascular biologyendothelial functioncell biologycardiovascular disease

A Novel Automated Method for Comprehensive Renal Cast Quantification From Rat Kidney Sections Using Qupath. AJP Renal Physiology (2024)

Lauren YunkerMegan Cleland HarwigAlison J. Kriegel

physiologykidney researchrat kidney sectionsrenal functionnephrologyrenal pathophysiology

Human Fis1 Directly Interacts With Drp1 in an Evolutionarily Conserved Manner to Promote Mitochondrial Fission. Journal of Biological Chemistry (2023)

Kelsey A. NoldenMegan C. HarwigR. Blake Hill

mitochondrial fissionmolecular biologybiological chemistryevolutionary biologybiochemistry

The Variable Domain From Dynamin‐Related Protein 1 Promotes Liquid–Liquid Phase Separation That Enhances Its Interaction With Cardiolipin‐Containing Membranes. Protein Science (2023)

Ammon E. PoseyKyle A. RossMehran BagheriElizabeth N. LanumMisha A. KhanChristine E. JenningsMegan C. HarwigNolan W. KennedyVincent J. HilserJames L. HardenR. Blake Hill

The Variable Domain From the Mitochondrial Fission Mechanoenzyme Drp1 Promotes Liquid-Liquid Phase Separation. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Ammon E. PoseyMehran BagheriKyle A. RossElizabeth N. LanumMisha A. KhanChristine M. JenningsMegan C. HarwigNolan W. KennedyVincent J. HilserJames L. HardenR. Blake Hill

liquid-liquid phase separationbiophysicsprotein structurevariable domainmolecular biologymembrane biologystructural biologyphase separationbiological engineering

Histone H3 and H4 Tails Play an Important Role in Nucleosome Phase Separation. Biophysical Chemistry (2022)

Erin F. HammondsMegan Cleland HarwigEmeleeta A. PaintsilEmma A. TillisonR. Blake HillEmma A. Morrison

nucleosome phase separationbiophysical chemistrybiophysics

Novel Dnm1L Variants Impair Mitochondrial Dynamics Through Divergent Mechanisms. Life Science Alliance (2022)

mitochondrial dynamicsgeneticsbiologygenetic variationmolecular biologydivergent mechanisms

Structural Studies of Human Fission Protein Fis1 Reveal a Dynamic Region Important for Gtpase Drp1 Recruitment and Mitochondrial Fission. Journal of Biological Chemistry (2022)

biophysicsstructural studieshuman fission proteinmolecular biologystructural biologydynamic regionbiochemistry

Intramolecular Regulation of Fis1 Activity in Fission and Mitophagy. The FASEB Journal (2021)

Ugochukwu IhenachoJohn EgnerMegan HarwigBlake Hill

Mitochondrial Fission Protein 1: Emerging Roles in Organellar Form and Function in Health and Disease. Frontiers in Endocrinology (2021)

Ugochukwu Kelvin IhenachoKelsey A. MeachamMegan Cleland HarwigMichael E. WidlanskyR. Blake Hill

mitochondrial dynamicsmitochondrial fissionorganellar formendocrinologyredox biologymitochondrial functionmolecular biologymitochondrial biogenesisoxidative stress

1
2
3
10 / page

Similar Faculty Members

Rajesh Ramachandran

Institution

Case Western Reserve University

protein structure

protein science

Blake Hill

Institution

Medical College of Wisconsin

molecular biology

membrane protein

Daisy Sahoo, PhD

Institution

Medical College of Wisconsin

endocrinology

obesity

Daniel A Beard

Institution

University of Michigan

physiology

cardiology

Jason Mears

Institution

Case Western Reserve University

mitochondrial fission

molecular metabolism

Youming Xie

Institution

Wayne State University

molecular biology

translational proteomics

Olga Gursky

Institution

Boston University

protein modeling

biomolecular structure

Michael H. Elliott

Institution

University of Oklahoma

pediatrics

developmental behavioral pediatrics

Mariusz Karbowski

Institution

University of Maryland, Baltimore

mitochondrial membrane dynamics

molecular and cellular biology

Mikhail Alexeyev

Institution

University of South Alabama

cell biology

vascular biology

Similar Faculty Members

Rajesh Ramachandran

Institution

Case Western Reserve University

protein structure

protein science

Blake Hill

Institution

Medical College of Wisconsin

molecular biology

membrane protein

Daisy Sahoo, PhD

Institution

Medical College of Wisconsin

endocrinology

obesity

Daniel A Beard

Institution

University of Michigan

physiology

cardiology

Jason Mears

Institution

Case Western Reserve University

mitochondrial fission

molecular metabolism

Youming Xie

Institution

Wayne State University

molecular biology

translational proteomics

Olga Gursky

Institution

Boston University

protein modeling

biomolecular structure

Michael H. Elliott

Institution

University of Oklahoma

pediatrics

developmental behavioral pediatrics

Mariusz Karbowski

Institution

University of Maryland, Baltimore

mitochondrial membrane dynamics

molecular and cellular biology

Mikhail Alexeyev

Institution

University of South Alabama

cell biology

vascular biology